Abstract:
:Pulmonary hypertension (PH) is a progressive, fatal pulmonary circulatory disease that accompanies many conditions (including left to right side shunt) with compensatory elevated cardiac output. PH also complicates chronic hemodialysis (HD) therapy immediately after the creation of an arteriovenous (AV) access, even before starting HD therapy. It tends to regress after temporary AV access closure and after successful kidney transplantation. Affected patients have significantly higher cardiac output. This syndrome is associated with a statistically significant survival disadvantage. The laboratory hallmark of this syndrome is reduced basal and stimulatory nitric oxide (NO) levels. It appears that patients with end-stage renal disease (ESRD) acquire endothelial dysfunction that reduces the ability of their pulmonary vessels to accommodate the AV access-mediated elevated cardiac output, exacerbating the PH. Doppler echocardiographic screening of ESRD patients scheduled for HD therapy for the occurrence of PH is indicated. Early diagnosis enables timely intervention, currently limited to changing dialysis modality or referring for kidney transplantation.
journal_name
Semin Dialjournal_title
Seminars in dialysisauthors
Yigla M,Abassi Z,Reisner SA,Nakhoul Fdoi
10.1111/j.1525-139X.2006.00186.xsubject
Has Abstractpub_date
2006-09-01 00:00:00pages
353-7issue
5eissn
0894-0959issn
1525-139Xpii
SDI186journal_volume
19pub_type
杂志文章,评审abstract::In this article we deal with three aspects of acidosis in patients with chronic renal insufficiency: clinical characteristics, pathophysiology, and therapeutic approach. ...
journal_title:Seminars in dialysis
pub_type: 杂志文章,评审
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journal_title:Seminars in dialysis
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journal_title:Seminars in dialysis
pub_type: 社论,评审
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journal_title:Seminars in dialysis
pub_type: 杂志文章
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journal_title:Seminars in dialysis
pub_type: 杂志文章,评审
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journal_title:Seminars in dialysis
pub_type: 杂志文章
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journal_title:Seminars in dialysis
pub_type: 杂志文章,评审
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journal_title:Seminars in dialysis
pub_type: 杂志文章
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journal_title:Seminars in dialysis
pub_type: 杂志文章,评审
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更新日期:2011-05-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 杂志文章,评审
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更新日期:2017-11-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2016-07-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 杂志文章,评审
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更新日期:2007-01-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 杂志文章
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更新日期:2015-03-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 社论
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更新日期:2002-09-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 杂志文章,评审
doi:10.1111/j.1525-139x.2004.17112.x
更新日期:2004-01-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 杂志文章,评审
doi:10.1111/sdi.12599
更新日期:2017-07-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 杂志文章,评审
doi:10.1111/j.1525-139X.2006.00179.x
更新日期:2006-07-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 杂志文章
doi:10.1111/j.1525-139X.2008.00537.x
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journal_title:Seminars in dialysis
pub_type: 杂志文章,评审
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更新日期:2011-05-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 杂志文章,评审
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更新日期:2007-09-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 杂志文章
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更新日期:2011-11-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 杂志文章
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更新日期:2010-03-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 杂志文章
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journal_title:Seminars in dialysis
pub_type: 杂志文章,评审
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更新日期:2007-11-01 00:00:00
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journal_title:Seminars in dialysis
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journal_title:Seminars in dialysis
pub_type: 杂志文章,评审
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更新日期:2009-11-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 社论
doi:10.1111/sdi.12712
更新日期:2018-09-01 00:00:00
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journal_title:Seminars in dialysis
pub_type: 杂志文章
doi:10.1111/sdi.12904
更新日期:2020-07-23 00:00:00