A systematic review of treatments for mild traumatic brain injury.

Abstract:

OBJECTIVES:To assess the effectiveness of interventions for mild traumatic brain injury (MTBI) in adults as found in the literature. RESEARCH DESIGN:Systematic review of the literature. METHODS:Six electronic databases and 18 journals within the brain injury field were manually searched between the years 1980-2003. References from articles were scanned for further literature. Studies that met broad inclusion criteria were subjected to a formal test of relevance. Those found to be relevant were qualitatively tested for their methodological soundness. RESULTS:One thousand and fifty-five studies were initially identified and 163 were assessed using the relevance tool, yielding 20 studies for review. Four categories of interventions were identified: Pharmacotherapy, Cognitive Rehabilitation, Patient Education and Other. The majority of studies were weak, however there is evidence to support the effectiveness of patient education interventions. CONCLUSIONS:There are few rigorous studies evaluating treatment of MTBI. Limitations of the current literature are presented.

journal_name

Brain Inj

journal_title

Brain injury

authors

Comper P,Bisschop SM,Carnide N,Tricco A

doi

10.1080/02699050400025042

subject

Has Abstract

pub_date

2005-10-01 00:00:00

pages

863-80

issue

11

eissn

0269-9052

issn

1362-301X

journal_volume

19

pub_type

杂志文章,评审
  • Social-cue perception and mentalizing ability following traumatic brain injury: A human-robot interaction study.

    abstract:PRIMARY OBJECTIVE:Research studies and clinical observations of individuals with traumatic brain injury (TBI) indicate marked deficits in mentalizing-perceiving social information and integrating it into judgements about the affective and mental states of others. The current study investigates social-cognitive mechanis...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/02699052.2018.1531305

    authors: Mutlu B,Duff M,Turkstra L

    更新日期:2019-01-01 00:00:00

  • Use of the Westmead PTA scale to monitor recovery of memory after mild head injury.

    abstract:STUDY OBJECTIVE:Duration of post-traumatic amnesia (PTA) is an important index of severity of head injury. Retrospective assessment of PTA duration is arguably unreliable. Existing objective measures of PTA duration are designed for use over a 24-hour timeframe and, therefore, are not useful for assessing PTA following...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/02699050310001646152

    authors: Ponsford J,Willmott C,Rothwell A,Kelly AM,Nelms R,Ng KT

    更新日期:2004-06-01 00:00:00

  • Effects of intensive repetition of a new facilitation technique on motor functional recovery of the hemiplegic upper limb and hand.

    abstract:OBJECTIVE:To study the effects on the hemiplegic upper limb of repetitive facilitation exercises (RFEs) using a novel facilitation technique, in which the patient's intention to move the hemiplegic upper limb or finger was followed by realization of the movement using multiple sensory stimulations. METHODS:Twenty-thre...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.3109/02699052.2010.506855

    authors: Kawahira K,Shimodozono M,Etoh S,Kamada K,Noma T,Tanaka N

    更新日期:2010-01-01 00:00:00

  • Investigating ioflupane I123 injection and single photon emission tomography as an imaging biomarker for long-term sequelae following mild traumatic brain injury.

    abstract:OBJECTIVE:To determine whether there were differences in clinical outcomes for ioflupane I123 injection (DaTscan) and single photon emission tomography consistent with early Parkinson's disease (PD) among individuals with a history of mild traumatic brain injury (mTBI). METHODS:We performed a case-control study among ...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/02699052.2017.1388443

    authors: Reams N,Anderson J,Perlman R,Li W,Walters S,Tideman S,Wang C,Simon K,Frigerio R,Maraganore DM

    更新日期:2018-01-01 00:00:00

  • Effects of local administration of allogenic adipose tissue-derived mesenchymal stem cells on functional recovery in experimental traumatic brain injury.

    abstract:OBJECTIVE:Traumatic brain injury (TBI) is the leading cause of mortality and morbidity in paediatric patients after the first year of life. The aim of this study was to evaluate effects of locally administered allogeneic mesenchymal stem cells (MSC), in the acute period after a TBI. METHODOLOGY:MSC were isolated from ...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.3109/02699052.2015.1053525

    authors: Mastro-Martínez I,Pérez-Suárez E,Melen G,González-Murillo Á,Casco F,Lozano-Carbonero N,Gutiérrez-Fernández M,Díez-Tejedor E,Casado-Flores J,Ramírez-Orellana M,Serrano-González A

    更新日期:2015-01-01 00:00:00

  • 'We are the forgotten victims': Perspectives of adult siblings of persons with traumatic brain injury.

    abstract:PRIMARY OBJECTIVE:This study determined how the lives of a cross-national sample of adult siblings had changed since their brothers and sisters incurred a traumatic brain injury. RESEARCH DESIGN:A total of 272 participants provided responses to the question, 'How is your life different since your sibling had a TBI?' R...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.3109/02699052.2010.514317

    authors: Degeneffe CE,Olney MF

    更新日期:2010-01-01 00:00:00

  • The good-old-days bias and post-concussion syndrome symptom reporting in a non-clinical sample.

    abstract:PRIMARY OBJECTIVE:To investigate the good-old-days bias, a psychosocial factor associated with post-concussion syndrome (PCS). STUDY DESIGN:Repeated measures comparison of PCS symptoms reported 6 months prior (retrospectively) and currently. A non-clinical sample was used to determine if this bias is a general recall ...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.3109/02699052.2012.666367

    authors: Sullivan KA,Edmed SL

    更新日期:2012-01-01 00:00:00

  • The malingering of multiple sclerosis and mild traumatic brain injury.

    abstract::In this investigation, neuropsychological testing was conducted with 69 college students that were instructed to malinger either multiple sclerosis (MS) or traumatic brain injury (TIB) or were non-malingering controls. The two malingering groups were divided into informed and non-informed groups. The informed groups r...

    journal_title:Brain injury

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/026990597123502

    authors: Klimczak NJ,Donovick PJ,Burright R

    更新日期:1997-05-01 00:00:00

  • Impersistent execution of saccadic eye movements after traumatic brain injury.

    abstract::A dynamic scoring system was developed to quantitatively resolve the ability of a subject to persistently execute a repeated motor act. Saccadic eye movements in response to pseudo-random and periodic stimuli were examined in patients with traumatic brain injury (TBI) and in normal subjects. Results indicated signific...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.3109/02699059509008233

    authors: Glass I,Groswasser Z,Groswasser-Reider I

    更新日期:1995-11-01 00:00:00

  • Effectiveness of valproic acid on destructive and aggressive behaviours in patients with acquired brain injury.

    abstract::Valproic acid, a primary anticonvulsant drug, has recently been studied for purported effectiveness in disparate disorders of mood and behaviour. The psychopharmacological treatment of patients with acquired brain injury frequently includes numerous trials of psychotherapeutic drugs such as antipsychotics, benzodiazep...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/026990597123791

    authors: Wroblewski BA,Joseph AB,Kupfer J,Kalliel K

    更新日期:1997-01-01 00:00:00

  • The Immediate Post-Concussion Assessment and Cognitive Testing battery and traditional neuropsychological measures: a construct and concurrent validity study.

    abstract:PRIMARY OBJECTIVE:This study examined the construct and concurrent validity of ImPACT, a computerized neuropsychological test battery used for evaluating sports-related concussion. RESEARCH DESIGN:Approximately 100 neurologically intact undergraduates completed ImPACT and a battery of traditional neuropsychological te...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.3109/02699052.2010.541897

    authors: Allen BJ,Gfeller JD

    更新日期:2011-01-01 00:00:00

  • The unveiling of traumatic brain injury in an HIV/AIDS population.

    abstract::This study examines the frequency of traumatic brain injury (TBI) in an HIV/AIDS population and its associated symptomatology. A panel of 173 individuals with HIV were split into two groups--those who have experienced a blow to the head within their lifetime (n = 128) and those who have not (n = 45). Self-reported sym...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/026990500120916

    authors: Jaffe MP,O'Neill J,Vandergoot D,Gordon WA,Small B

    更新日期:2000-01-01 00:00:00

  • Relationships between kinesiotherapy methods used in rehabilitation and the course of lost function recovery following surgical treatment of cranio-cerebral trauma.

    abstract:INTRODUCTION AND AIM:This paper aims to outline the relationships between kinesiotherapy methods used in rehabilitation and the recovery of the patient's ability to perform activities of daily living (ADLs), improvement of functional condition, regression of pareses and improvement of conscious state following surgical...

    journal_title:Brain injury

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/02699052.2012.694562

    authors: Brzuszkiewicz-Kuźmicka G,Kuźmicki S,Domaniecki J

    更新日期:2012-01-01 00:00:00

  • Community re-entry of long-term institutionalized brain-injured persons.

    abstract::Although evidence exists for delayed recovery after traumatic brain injury, patients who do not receive rehabilitation early after their injuries often remain permanently in long-term care facilities. Case reports of five severely brain-injured persons who were discharged into long-term nursing care facilities for at ...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.3109/02699059509008201

    authors: Bell KR,Tallman CA

    更新日期:1995-04-01 00:00:00

  • In search of evidence-based treatment for concussion: characteristics of current clinical trials.

    abstract:UNLABELLED:Abstract Objective: To assess the characteristics of current clinical trials investigating the treatment of concussion. BACKGROUND:Recent systematic literature reviews have concluded that there is minimal evidence to support any specific treatment for concussion, including the principles of return-to-activi...

    journal_title:Brain injury

    pub_type: 杂志文章,评审

    doi:10.3109/02699052.2014.974673

    authors: Burke MJ,Fralick M,Nejatbakhsh N,Tartaglia MC,Tator CH

    更新日期:2015-01-01 00:00:00

  • Neuroendocrine dysfunction in acute phase of moderate-to-severe traumatic brain injury: a prospective study.

    abstract:OBJECTIVES:Most of the retrospective studies have demonstrated that traumatic brain injury mediated hypopituitarism could be more frequent than previously known. Therefore, this study has prospectively investigated pituitary function and their correlation with severity, pressure effect and Glasgow Outcome Scale in the ...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.3109/02699052.2014.955882

    authors: Prasanna KL,Mittal RS,Gandhi A

    更新日期:2015-01-01 00:00:00

  • Snoezelen: a controlled multi-sensory stimulation therapy for children recovering from severe brain injury.

    abstract:OBJECTIVE:To investigate the effects of Snoezelen therapy on physiological, cognitive and behavioural changes in children recovering from severe traumatic brain injury (TBI). METHODS:An observational study was conducted to assess the physiological, cognitive and behavioural changes of children recovering from severe T...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/02699050600832635

    authors: Hotz GA,Castelblanco A,Lara IM,Weiss AD,Duncan R,Kuluz JW

    更新日期:2006-07-01 00:00:00

  • Neuropsychological functioning during the year following severe traumatic brain injury.

    abstract::The neuropsychological functioning of a group of 65 adults with severe traumatic brain injury was assessed at 6 months and 1 year post-injury. The cognitive domains assessed were pre-morbid intellectual level, current level of general intellectual functioning, simple and complex attention, verbal memory, executive fun...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/02699050010005887

    authors: Kersel DA,Marsh NV,Havill JH,Sleigh JW

    更新日期:2001-04-01 00:00:00

  • The utility of the Convergence Insufficiency Symptom Survey (CISS) post-concussion.

    abstract::Background: The Convergence Insufficiency Symptom Survey (CISS) is being utilized as an assessment measure following concussion despite minimal research. This study explored the sensitivity and specificity of the CISS in identifying receded near point of convergence (NPC) post-concussion. Methods: Prospective study of...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/02699052.2019.1658131

    authors: Trbovich AM,Sherry NK,Henley J,Emami K,Kontos AP

    更新日期:2019-01-01 00:00:00

  • Combined application of polyacrylate scaffold and lipoic acid treatment promotes neural tissue reparation after brain injury.

    abstract:PRIMARY OBJECTIVE:The aim of this study was to investigate the reparative potential of a polymeric scaffold designed for brain tissue repair in combination with lipoic acid. RESEARCH DESIGN:Histological, cytological and structural analysis of a combined treatment after a brain cryo-injury model in rats. METHODS AND P...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.3109/02699052.2015.1091505

    authors: Rocamonde B,Paradells S,Garcia Esparza MA,Vives MS,Sauro S,Ramos CM,Pradas MM,Soria JM

    更新日期:2016-01-01 00:00:00

  • The ethics of using placebo medication in a non-capacitous patient.

    abstract:BACKGROUND:The use of placebo has long been controversial. Whilst evidence accumulates regarding it's beneficial and safe effects, ethical issues around the eroding of patient autonomy and accusations of deception stop most doctors prescribing inert placebo substances. CASE STUDY:This paper presents a case of a non-ca...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.3109/02699052.2012.694560

    authors: Bolton P,Shotton L,Young A,Grace J

    更新日期:2012-01-01 00:00:00

  • Psychometric properties of the simple test for evaluating hand function in patients with stroke.

    abstract:OBJECTIVE:The simple test for evaluating hand function (STEF) is widely used for clinical evaluation of upper extremity function in Japan. However, except for test-re-test reliability, its psychometric properties have not been investigated. The aim of this study is to explore its internal consistency, concurrent validi...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.3109/02699052.2015.1004740

    authors: Shindo K,Oba H,Hara J,Ito M,Hotta F,Liu M

    更新日期:2015-01-01 00:00:00

  • Assessing recovery in middle cerebral artery stroke using functional MRI.

    abstract:PRIMARY OBJECTIVE:To understand the temporal evolution of brain reorganization during recovery from stroke. RESEARCH DESIGN:A patient who suffered left middle cerebral artery stroke 9 months earlier was studied on three occasions, approximately 1 month apart. METHODS AND PROCEDURES:Brain activation was studied using ...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/02699050500149858

    authors: Nair DG,Fuchs A,Burkart S,Steinberg FL,Kelso JA

    更新日期:2005-12-01 00:00:00

  • Correlation of atrophy measures on MRI with neuropsychological sequelae in children and adolescents with traumatic brain injury.

    abstract::To examine the relationship between neuropsychological sequelae and atrophy parameters from magnetic resonance imaging (MRI) following paediatric moderate-to-severe traumatic brain injury (TBI), 19 head injured children and adolescents were studied at least 6 years after injury. Three-dimensional MRI scans were obtain...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/02699050010004059

    authors: Verger K,Junqué C,Levin HS,Jurado MA,Pérez-Gómez M,Bartrés-Faz D,Barrios M,Alvarez A,Bartumeus F,Mercader JM

    更新日期:2001-03-01 00:00:00

  • Neurofilament light and tau in serum after head-impact exposure in soccer.

    abstract::Introduction: Blood-based biomarkers can provide valuable information on the effects of repetitive head impacts in sports. This study investigated if repetitive headers or accidental head impacts in soccer could cause structural brain injury, detected as an increase in serum neurofilament light (NfL) or tau.Methods: N...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/02699052.2020.1725129

    authors: Sandmo SB,Filipcik P,Cente M,Hanes J,Andersen TE,Straume-Naesheim TM,Bahr R

    更新日期:2020-04-15 00:00:00

  • The use of bupropion in the treatment of restlessness after a traumatic brain injury.

    abstract::The occurrence of restlessness after a traumatic brain injury (TBI) is common. Severe restlessness can be a barrier in the multidisciplinary treatment of patients with TBI. The following case describes a patient with restlessness after a head-on motor vehicle accident. The patient was tachycardic, diaphoretic, demonst...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/02699050010005931

    authors: Teng CJ,Bhalerao S,Lee Z,Farber J,Morris H,Foran T,Tucker W

    更新日期:2001-05-01 00:00:00

  • Short-term neurocognitive and symptomatic outcomes following mild traumatic brain injury: A prospective multi-centre observational cohort study.

    abstract:OBJECTIVE:To determine the short-term cognitive and symptomatic outcome following mild traumatic brain injury. METHODS:Setting: Emergency Departments of two UK tertiary referral hospitals. PARTICIPANTS:Adult patients presenting to the Emergency Departments of the Royal London Hospital and Salford Royal Hospital with ...

    journal_title:Brain injury

    pub_type: 杂志文章,多中心研究

    doi:10.1080/02699052.2016.1256501

    authors: Bloom BM,Kinsella K,Pott J,Patel HC,Harris T,Lecky F,Pearse R

    更新日期:2017-01-01 00:00:00

  • After traumatic brain injury: a discussion of consequences.

    abstract::Traumatic brain injury is followed by many changes in cognition, emotion, social interaction and functioning, and communication. These changes may range from severe to subtle. They create complex difficulties for the individual and his or her network of support. Presented here is a review of the literature on the chan...

    journal_title:Brain injury

    pub_type: 杂志文章,评审

    doi:10.3109/02699059409151016

    authors: Stratton MC,Gregory RJ

    更新日期:1994-10-01 00:00:00

  • Seeing minds in patients with disorders of consciousness.

    abstract::Objective: To explore the ways in which health care professionals and families understand terms and concepts associated with disorders of consciousness.Methods: Open-ended, semi-structured interviews were conducted with 20 health care professionals and 18 family caregivers affiliated with a disorders of consciousness ...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/02699052.2019.1706000

    authors: Peterson A,Kostick KM,O'Brien KA,Blumenthal-Barby J

    更新日期:2020-02-23 00:00:00

  • Functional recovery following traumatic vs non-traumatic brain injury: a case-controlled study.

    abstract:PRIMARY OBJECTIVE:To explore differences in rate of recovery and functional outcome in case-matched patients with traumatic (TBI) vs non-traumatic brain injury (non-TBI) during inpatient rehabilitation and 1 year post-insult. RESEARCH DESIGN:Retrospective comparison study and case-controlled design. METHODS AND PROCE...

    journal_title:Brain injury

    pub_type: 杂志文章

    doi:10.1080/02699050802530581

    authors: Cullen NK,Park YG,Bayley MT

    更新日期:2008-12-01 00:00:00