Correlation of atrophy measures on MRI with neuropsychological sequelae in children and adolescents with traumatic brain injury.

Abstract:

:To examine the relationship between neuropsychological sequelae and atrophy parameters from magnetic resonance imaging (MRI) following paediatric moderate-to-severe traumatic brain injury (TBI), 19 head injured children and adolescents were studied at least 6 years after injury. Three-dimensional MRI scans were obtained. A semi-automatic computerized method was used to estimate ventricular volumes and the corpus callosum area. Tests of intellectual, memory, visuospatial, frontal lobe, and motor speed functioning were administered to all patients and to 19 matched normal control subjects. Patients' performance significantly differed from controls in general intellectual function, visual memory, visuospatial and frontal lobe tests. The corpus callosum area correlated strongly with several measures involving processing speed and visuospatial function. Ventricular enlargement was less related to neuropsychological outcome. In conclusion, quantitative measurement of the corpus callosum on MRI reflects neuropsychological outcome better than ventricular dilation in paediatric patients.

journal_name

Brain Inj

journal_title

Brain injury

authors

Verger K,Junqué C,Levin HS,Jurado MA,Pérez-Gómez M,Bartrés-Faz D,Barrios M,Alvarez A,Bartumeus F,Mercader JM

doi

10.1080/02699050010004059

subject

Has Abstract

pub_date

2001-03-01 00:00:00

pages

211-21

issue

3

eissn

0269-9052

issn

1362-301X

journal_volume

15

pub_type

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