Health, economic evaluation, and critical care.

Abstract:

:In the past 2 decades, societal spending on health care has become an international concern. The United States currently spends more than 1.6 trillion dollars per year on health care--approximately 15% of the gross domestic product. The provision of care to critically ill patients accounts for a disproportionate share of these health care dollars--approximately 13% of hospital costs, 4% of national health expenditures, and 0.5% to 1% of the gross domestic product. This enormous investment necessitates careful evaluation of our interventions and their associated expense. Economic evaluation can aid policy makers and health care professionals in comparing the relative and incremental value of disparate and expensive therapies and also inform decisions about which interventions provide good value for the health care dollar. In this review, we will highlight landmark publications over the past decades that have helped to shape the field of economic evaluations for critical care medicine.

journal_name

J Crit Care

journal_title

Journal of critical care

authors

Alsarraf AA,Fowler R

doi

10.1016/j.jcrc.2005.05.004

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

194-7

issue

2

eissn

0883-9441

issn

1557-8615

pii

S0883-9441(05)00041-9

journal_volume

20

pub_type

杂志文章
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    pub_type: 杂志文章,meta分析

    doi:10.1016/j.jcrc.2014.11.008

    authors: Zhang L,Chen J,Jiang D,Zhang P

    更新日期:2015-04-01 00:00:00

  • Effectiveness of end-expiratory lung volume measurements during the lung recruitment maneuver for patients with atelectasis.

    abstract:PURPOSE:The aim of this study was to determine whether the relative change in the end-expiratory lung volume (EELV) obtained by the recruitment maneuver (RM) can serve as an indicator of the change in the P/F ratio. MATERIALS AND METHODS:The effects of the intermittent stepwise increases in the RM (peak inspiratory pr...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2012.11.003

    authors: Nakahashi S,Gando S,Ishikawa T,Wada T,Yanagida Y,Kubota N,Uegaki S,Hayakawa M,Sawamura A

    更新日期:2013-08-01 00:00:00

  • Troponin-I as a prognosticator of mortality in severe sepsis patients.

    abstract:PURPOSE:The purpose of this retrospective study was to evaluate cardiac troponin-I (cTnI) as a 28-day mortality prognosticator and predictor for a drotrecogin alfa (activated) (DrotAA) survival benefit in recombinant human activated Protein C Worldwide Evaluation in Severe Sepsis patients. METHODS:Cardiac troponin-I w...

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    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2009.12.001

    authors: John J,Woodward DB,Wang Y,Yan SB,Fisher D,Kinasewitz GT,Heiselman D

    更新日期:2010-06-01 00:00:00

  • Treatment of severe coagulopathy after gunshot injury to the head using recombinant activated factor VII.

    abstract:PURPOSE:Patients with severe penetrating head injury often have a coagulopathy that is difficult to correct. In this report, we describe 3 such patients who were treated with activated factor VII (FVIIa) to stop ongoing hemorrhage that was refractory to conventional treatment. SUBJECTS AND METHODS:We treated 3 patient...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2005.02.004

    authors: Aiyagari V,Menendez JA,Diringer MN

    更新日期:2005-06-01 00:00:00

  • Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients.

    abstract:OBJECTIVE:Serum concentrations of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, may contribute to endothelial dysfunction and organ failure in sepsis. We aimed at investigating ADMA levels as a potential diagnostic or prognostic biomarker in critically ill patients. METHODS:Two ...

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    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2013.05.016

    authors: Koch A,Weiskirchen R,Kunze J,Dückers H,Bruensing J,Buendgens L,Matthes M,Luedde T,Trautwein C,Tacke F

    更新日期:2013-12-01 00:00:00

  • Changes in internal medicine residents' attitudes about resuscitation after cardiac arrest over a decade.

    abstract:BACKGROUND:Resident physicians' beliefs about cardiopulmonary resuscitation (CPR) may impact their communication with patients about end-of-life care. We sought to understand how these perceptions and experiences have changed in the past decade because both medical education and American society have focused more on th...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2007.12.012

    authors: Deep KS,Griffith CH,Wilson JF

    更新日期:2009-03-01 00:00:00

  • Prognostic nomogram for acute pancreatitis patients: An analysis of publicly electronic healthcare records in intensive care unit.

    abstract:PURPOSE:The mortality rate of severe acute pancreatitis (AP) is 20-30% even after admission to intensive care unit (ICU). Thus we aimed to develop a laboratory-based nomogram to identify AP patients at high risk for mortality. MATERIALS AND METHODS:The primary and validation cohorts were extracted from the Medical Inf...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2018.10.030

    authors: Jiang X,Su Z,Wang Y,Deng Y,Zhao W,Jiang K,Sun C

    更新日期:2019-04-01 00:00:00

  • The impact of non-blinding in critical care medicine trials.

    abstract:PURPOSE:It is uncertain whether, in critical care medicine, non-blinded trials are associated with a bias toward a different effect size. The aim of our study was to assess if conducting non-blinded/open label studies leads to greater effect size than blinded studies, and to provide an estimate of the weight of this di...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2018.09.031

    authors: Baiardo Redaelli M,Belletti A,Monti G,Lembo R,Ortalda A,Landoni G,Bellomo R

    更新日期:2018-12-01 00:00:00

  • The role of human metapneumovirus in the critically ill adult patient.

    abstract:PURPOSE:The purpose of the study is to describe the role of human metapneumovirus (hMPV) infection in critical illness and acute respiratory distress syndrome (ARDS). MATERIALS AND METHODS:We collected clinical and demographic information from a retrospective chart review, comparing patients with and without an intens...

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    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2015.09.035

    authors: Hasvold J,Sjoding M,Pohl K,Cooke C,Hyzy RC

    更新日期:2016-02-01 00:00:00

  • Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: prevention.

    abstract:BACKGROUND:Ventilator-associated pneumonia (VAP) is an important cause of morbidity and mortality in ventilated critically ill patients. PURPOSE:To develop evidence-based guidelines for the prevention of VAP. DATA SOURCES:MEDLINE, EMBASE, CINAHL, and the Cochrane Database of Systematic Reviews and Register of Control...

    journal_title:Journal of critical care

    pub_type: 杂志文章,实务指引

    doi:10.1016/j.jcrc.2007.11.014

    authors: Muscedere J,Dodek P,Keenan S,Fowler R,Cook D,Heyland D,VAP Guidelines Committee and the Canadian Critical Care Trials Group.

    更新日期:2008-03-01 00:00:00

  • Comparison of circuit patency and exchange rates between 2 different continuous renal replacement therapy machines.

    abstract:BACKGROUND:Continuous renal replacement therapy (CRRT) is an important tool in the care of critically ill patients. However, the impact of a specific CRRT machine type on the successful delivery of CRRT is unclear. The purpose of this study was to evaluate the effectiveness of CRRT delivery with an intensive care unit ...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2013.11.012

    authors: Razavi SA,Still MD,White SJ,Buchman TG,Connor MJ Jr

    更新日期:2014-04-01 00:00:00

  • A noninvasive method for monitoring cerebral perfusion during cardiopulmonary resuscitation.

    abstract:PURPOSE:This study evaluates the use of transcranial Doppler (TCD) ultrasound in assessing the changes experienced by the cerebral circulation during cardiopulmonary resuscitation (CPR) and compares it with measurements of internal carotid artery (ICA) flow rates (ultrasonic flow-meter measurements) and cerebral blood ...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/0883-9441(94)90013-2

    authors: Lewis LM,Stothert JC Jr,Gomez CR,Ruoff BE,Hall IS,Chandel B,Standeven J

    更新日期:1994-09-01 00:00:00

  • The influence of anesthesia on heart rate complexity during elective and urgent surgery in 128 patients.

    abstract:BACKGROUND:As an emerging "new vital sign," heart rate complexity (by sample entropy [SampEn]) has been shown to be a useful trauma triage tool by predicting occult physiologic compromise and need for life-saving interventions. Sample entropy may be confounded by anesthesia possibly limiting its value intraoperatively....

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    pub_type: 杂志文章

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    authors: Naraghi L,Peev MP,Esteve R,Chang Y,Berger DL,Thayer SP,Rattner DW,Lillemoe KD,Kaafarani H,Yeh DD,de Moya MA,Fagenholz PJ,Velmahos GS,King DR

    更新日期:2015-02-01 00:00:00

  • N-terminal pro-brain natriuretic peptide and cardiac troponin I for the prognostic utility in elderly patients with severe sepsis or septic shock in intensive care unit: A retrospective study.

    abstract:BACKGROUNDS:Using biomarkers to predict mortality in patient with severe sepsis or septic shock is of importance, as these patients frequently have high mortality and unsatisfied outcome. N-terminal pro-brain natriuretic peptide (NT-proBNP) and cardiac troponin I (cTnI) play extremely important roles in prognostic valu...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2014.12.008

    authors: Cheng H,Fan WZ,Wang SC,Liu ZH,Zang HL,Wang LZ,Liu HJ,Shen XH,Liang SQ

    更新日期:2015-06-01 00:00:00

  • The clinical features of severe community-acquired pneumonia presenting as septic shock. Norasept II Study Investigators.

    abstract:PURPOSE:The purpose of this article was to determine the outcome, clinical and prognostic features, and microbiology of a large group of patients with community-acquired pneumonia (CAP) presenting in septic shock. MATERIALS AND METHODS:The placebo limb of the Norasept II database was examined. Data were collected on p...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1053/jcrc.2000.16460

    authors: Marik PE

    更新日期:2000-09-01 00:00:00

  • A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19.

    abstract:PURPOSE:COVID-19 (coronavirus disease 2019) is a public health emergency of international concern. As of this time, there is no known effective pharmaceutical treatment, although it is much needed for patient contracting the severe form of the disease. The aim of this systematic review was to summarize the evidence reg...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2020.03.005

    authors: Cortegiani A,Ingoglia G,Ippolito M,Giarratano A,Einav S

    更新日期:2020-06-01 00:00:00

  • Intensive care admission criteria for traumatic brain injury patients across Europe.

    abstract::Within a prospective, observational, multi-center cohort study 68 hospitals (of which 66 responded), mostly academic (n = 60, 91%) level I trauma centers (n = 44, 67%) in 20 countries were asked to complete questionnaires regarding the "standard of care" for severe neurotrauma patients in their hospitals. From the que...

    journal_title:Journal of critical care

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jcrc.2018.11.002

    authors: Volovici V,Ercole A,Citerio G,Stocchetti N,Haitsma IK,Huijben JA,Dirven CMF,van der Jagt M,Steyerberg EW,Nelson D,Cnossen MC,Maas AIR,Polinder S,Menon DK,Lingsma HF

    更新日期:2019-02-01 00:00:00

  • A modified Delphi process to identify clinical and research priorities in patient and family centred critical care.

    abstract:PURPOSE:To identify elements which enable patient and family centred care (PFCC) in the intensive care unit (ICU) and priorities for PFCC research. MATERIALS AND METHODS:We engaged a panel of multidisciplinary stakeholders in a modified Delphi process. Items generated from a literature review and panelist suggestions ...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2017.08.008

    authors: Oczkowski SJW,Au S,des Ordons AR,Gill M,Potestio ML,Smith O,Sinuff T,Stelfox HT,Fox-Robichaud AE

    更新日期:2017-12-01 00:00:00

  • Organ-specific therapy in critical illness: interfacing molecular mechanisms with physiological interventions.

    abstract::Sepsis and SIRS is the outward manifestation of a generalized uncontrolled inflammatory response, which, if sustained, induces widespread endothelial damage and MODS. Immunomodulating therapies, at present, have proven ineffective in reducing morbidity and mortality, presumably because of the heterogeneous nature of s...

    journal_title:Journal of critical care

    pub_type: 杂志文章,评审

    doi:10.1016/s0883-9441(96)90024-6

    authors: Pinsky MR

    更新日期:1996-06-01 00:00:00

  • Development of the continuous quality improvement questionnaire (CQIQ).

    abstract:PURPOSE:Increasingly, hospitals are engaging in continuous quality improvement (CQI) endeavors, aimed at optimizing patient care. Physician involvement is critical to the success of such initiatives. Little is known about any mediating factors that affect physician participation in these projects, though such knowledge...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1053/jcrc.2001.30165

    authors: Hill A,Gwadry-Sridhar F,Armstrong T,Sibbald WJ

    更新日期:2001-12-01 00:00:00

  • Are thromboelastometric and thromboelastographic parameters associated with mortality in septic patients? A systematic review and meta-analysis.

    abstract:BACKGROUND:Thromboelastometry/elastography (ROTEM/TEG) showed promising results for diagnosis of sepsis-induced coagulopathy, but their association with the outcome is unclear. Our aim was to assess any difference in ROTEM/TEG measurements between septic survivors and non-survivors. METHODS:Pubmed, Web of Science, Emb...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2020.09.034

    authors: Boscolo A,Spiezia L,De Cassai A,Pasin L,Pesenti E,Zatta M,Zampirollo S,Andreatta G,Sella N,Pettenuzzo T,Rose K,Simioni P,Navalesi P

    更新日期:2021-02-01 00:00:00

  • Two perspectives on organ donation: experiences of potential donor families and intensive care physicians of the same event.

    abstract::The aim was to explore how relatives and physicians understood cases where organ donation had been requested and what factors were salient for the decision on donation. Physicians of 25 deceased patients and 20 relatives were interviewed. The material was analyzed using qualitative methods. Eleven patients had declare...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2007.03.002

    authors: Sanner MA

    更新日期:2007-12-01 00:00:00

  • Heterogeneous effect of increasing spinal cord perfusion pressure on sensory evoked potentials recorded from acutely injured human spinal cord.

    abstract:PURPOSE:To investigate the effect of increasing spinal cord perfusion pressure (SCPP) on sensory evoked potentials (SEPs) and injury site metabolism in patients with severe traumatic spinal cord injury TSCI. MATERIALS AND METHODS:In 12 TSCI patients we placed a pressure probe, a microdialysis catheter and a strip elec...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2019.12.019

    authors: Gallagher MJ,López DM,Sheen HV,Hogg FRA,Zoumprouli A,Papadopoulos MC,Saadoun S

    更新日期:2020-04-01 00:00:00

  • Development and validation of a clinical prediction rule for candidemia in hospitalized patients with severe sepsis and septic shock.

    abstract:OBJECTIVE:To develop and internally validate a prediction rule for the presence of candidemia in patients with severe sepsis and septic shock (candidemia rule) that will fill the gap left by previous rules. To compare the accuracy of the available Candida prediction models. DESIGN:Retrospective cohort study. SETTING:...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2015.03.010

    authors: Guillamet CV,Vazquez R,Micek ST,Ursu O,Kollef M

    更新日期:2015-08-01 00:00:00

  • Characteristics and outcomes of HIV-1-infected patients with acute respiratory distress syndrome.

    abstract:PURPOSE:We determined the prevalence of risk factors for the development of acute respiratory distress syndrome (ARDS), outcomes of critical illness, and the impact of highly active antiretroviral therapy in HIV-1-infected patients. We hypothesized that in an urban county hospital, HIV-1-infected patients with ARDS wou...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2014.10.020

    authors: Nirappil FJ,Maheshwari A,Andrews J,Martin GS,Esper AM,Cribbs SK

    更新日期:2015-02-01 00:00:00

  • Which one is a better predictor of ICU mortality in septic patients? Comparison between serial serum lactate concentrations and its removal rate.

    abstract:PURPOSE:To predict 28-day mortality with serum lactate and oxygenation profile in sepsis. METHODS:82 patients were admitted to the ICU with sepsis. Comorbid disease, hemodynamic and oxygenation parameters were recorded. Serum lactate was measured at T0, T6, T12 and T24 hours of admission. Arterial and venous oxygen sa...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2017.10.019

    authors: Mahmoodpoor A,Shadvar K,Saghaleini SH,Koleini E,Hamishehkar H,Ostadi Z,Nader ND

    更新日期:2018-04-01 00:00:00

  • Highly visible sepsis publications from 2012 to 2017: Analysis and comparison of altmetrics and bibliometrics.

    abstract:PURPOSE:We sought to delineate highly visible publications related to sepsis. Within these subsets, elements of altmetrics performance, including mentions on Twitter, and the correlation between altmetrics and conventional citation counts were ascertained. MATERIALS AND METHODS:Three subsets of sepsis publications fro...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2018.09.033

    authors: Jabaley CS,Groff RF 4th,Stentz MJ,Moll V,Lynde GC,Blum JM,O'Reilly-Shah VN

    更新日期:2018-12-01 00:00:00

  • L-canavanine, a selective inhibitor of inducible NO synthase, increases plasma endothelin-1 concentrations in dogs with endotoxic shock.

    abstract:PURPOSE:The purpose of this article is to elucidate the effect of L-canavanine, a selective inhibitor of inducible NO synthase (iNOS), on hemodynamics, blood gas parameters, and plasma concentrations of lactate and endothelin-1 (ET-1) during endotoxic shock. MATERIALS AND METHODS:Eleven mongrel dogs under pentobarbita...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1053/jcrc.2001.21792

    authors: Mitaka C,Hirata Y,Yokoyama K,Imai T

    更新日期:2001-03-01 00:00:00

  • Continuous jugular bulb venous oxygen saturation validation and variations during intracranial aneurysm surgery.

    abstract:PURPOSE:During intracranial aneurysm surgery, numerous factors may alter cerebral blood flow and oxygen supply-demand balance. Continuous monitoring of jugular bulb venous oxygen saturation (SvjO2) may help in the anesthetic management of such procedures. MATERIALS AND METHODS:Fiberoptic SvjO2 was continuously monitor...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/s0883-9441(97)90040-x

    authors: Clavier N,Schurando P,Raggueneau JL,Payen DM

    更新日期:1997-09-01 00:00:00

  • Impaired renal function is associated with greater urinary strong ion differences in critically ill patients with metabolic acidosis.

    abstract:PURPOSE:Urinary excretion of chloride corrects metabolic acidosis, but this may be hampered in patients with impaired renal function. We explored the effects of renal function on acid-base characteristics and urinary strong ion excretion using the Stewart approach in critically ill patients with metabolic acidosis. MA...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2011.05.028

    authors: Moviat M,Terpstra AM,van der Hoeven JG,Pickkers P

    更新日期:2012-06-01 00:00:00