The effect of modafinil on self-esteem in spinal cord injury patients: a report of 2 cases and review of the literature.

Abstract:

:We report on 2 cases of the effect of modafinil on the self-esteem of patients with spinal cord injury (SCI). The first patient was a 33-year-old man with history of polysubstance abuse and a C6 American Spinal Injury Association (ASIA) grade A injury, who presented for follow-up to the outpatient rehabilitation clinic for depression, decreased motivation, and lowered self-esteem. The patient had tried a selective serotonin reuptake inhibitor (SSRI) without success, and reported increasing social and legal stressors. Within 1 month of starting on modafinil, he reported increased self-esteem and motivation, as well as decreased self-consciousness. The second patient was a 36-year-old woman with history of depression and a T11 ASIA grade A injury. She tried various SSRIs for depression and adjustment issues before she was started on modafinil. She lost weight and became more assertive and less self-conscious within 1 month after starting on modafinil. These 2 cases suggest that modafinil should be studied as a therapeutic option for treating lowered self-esteem in patients with SCI.

journal_name

Arch Phys Med Rehabil

authors

Mukai A,Costa JL

doi

10.1016/j.apmr.2005.01.009

subject

Has Abstract

pub_date

2005-09-01 00:00:00

pages

1887-9

issue

9

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(05)00217-0

journal_volume

86

pub_type

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