Genomic and evolutionary aspects of Mimivirus.

Abstract:

:We recently described a giant double stranded DNA virus called Mimivirus, isolated from amoebae, which might represent a new pneumonia-associated human pathogen. Its unique morphological and genomic characteristics allowed us to propose Mimivirus as a member of a new distinct Nucleocytoplasmic Large DNA viruses family, the Mimiviridae. Mimivirus-specific features, namely its size and its genomic complexity, ranged it between viruses and cellular organisms. This paper reviews our current knowledge on Mimivirus structure, life cycle and genome analysis and discusses its putative evolutionary origin in the tree of species of the three domains of life.

journal_name

Virus Res

journal_title

Virus research

authors

Suzan-Monti M,La Scola B,Raoult D

doi

10.1016/j.virusres.2005.07.011

subject

Has Abstract

pub_date

2006-04-01 00:00:00

pages

145-55

issue

1

eissn

0168-1702

issn

1872-7492

pii

S0168-1702(05)00237-6

journal_volume

117

pub_type

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