A randomized comparison of balloon angioplasty and stent implantation in the percutaneous treatment of coronary bifurcations.

Abstract:

OBJECTIVE:A prospective randomized multicentre pilot trial, comparing stenting with balloon angioplasty as a treatment for coronary lesions, located in a bifurcation was performed. METHODS AND RESULTS:After balloon dilatation, with a < 30% residual stenosis in the main vessel and < 50% residual stenosis in the side branch, patients were randomized to stay in a "balloon-only" group or to stenting. The stents used were the AVE S 670 for the main vessel and the Bestent, if needed, for the side branch. The primary end point was the incidence of major adverse cardiac events (MACE) at 6 months, secondary end points were in-hospital MACE, acute angiographic results, use of materials and duration of the procedure. One hundred eleven patients were randomized: 55 in the balloon group, 56 in the stent group. No differences in MACE-rates were found at 6 months (22% versus 20%, p = 0.78). The target vessel revascularization rate was 16% in the balloon group and 12.5% in the stent group (p = 0.56). The acute angiographic results were significantly better in the stent group (residual stenosis 8% versus 26% [p < 0.05]). More materials were used, with a near doubling of the duration of the procedure in the stent group (p < 0.05). CONCLUSIONS:Although stenting resulted in better immediate angiographic results during percutaneous treatment of lesions located in a bifurcation, as compared to balloon angioplasty alone, clinical events were comparable in the two treatment arms.

journal_name

Acta Cardiol

journal_title

Acta cardiologica

authors

Dens J,Dubois C,Vermeersch P,Coussement P,Vrolix M,Janssens L,Desmet W,Piessens J

doi

10.2143/AC.60.4.2004986

subject

Has Abstract

pub_date

2005-08-01 00:00:00

pages

379-85

issue

4

eissn

0001-5385

issn

1784-973X

journal_volume

60

pub_type

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