Comparative evaluation of the chemopreventive efficacy of green and black tea polyphenols in the hamster buccal pouch carcinogenesis model.

abstract：:Mycophenolate mofetil is widely used in combination with either cyclosporine or tacrolimus for rejection prophylaxis in renal and heart transplant patients. Although not monitored routinely nearly to the degree that other agents such as cyclosporine or tacrolimus, there is an expanding body of experimental evidence fo...

journal_title：Clinical biochemistry

authors： Shaw LM,Korecka M,DeNofrio D,Brayman KL

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVES:During the development of a testosterone assay by LC-MS/MS, we encountered significant assay interference introduced by blood collection tubes. We examined a number of commonly used blood collection tubes for the presence of interference and its impact on testosterone quantitation. DESIGN AND METHODS:A numb...

journal_title：Clinical biochemistry

authors： Shi RZ,van Rossum HH,Bowen RA

更新日期：2012-12-01 00:00:00

abstract：:Lipoprotein lipase (LPL) of adipose cells is present only in membrane compartments, mainly in the Golgi apparatus. LPL is a typical secretory protein which appears to be active as a homodimer. The process of LPL synthesis and maturation requires multiple steps. LPL is synthesized in the endoplasmic reticulum as an ina...

journal_title：Clinical biochemistry

authors： Ailhaud G

更新日期：1990-10-01 00:00:00

abstract：:Increasing interest in the use of tumor markers in the clinical management of cancer patients has encouraged development of guidelines by local, national and international groups. Such guidelines generally include recommendations about which markers are likely to be most helpful in given circumstances. Particular requ...

journal_title：Clinical biochemistry

authors： Sturgeon CM

更新日期：2001-07-01 00:00:00

abstract：:In hepatobiliary disease, the level of bile acids in the peripheral circulation is greatly increased due to impaired liver function. It has been suggested that serum bile acids are of greater value in confirming hepatobiliary dysfunction than the currently assayed conventional biochemical parameters. Fifty patients wi...

journal_title：Clinical biochemistry

authors： Jarzabek JI,Kampa IS

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:We evaluated the diagnostic efficacy of urinary angiogenin (ANG) and cytokeratin 20 (CK-20) mRNA in comparison with voided urine cytology in the detection of bladder cancer patients. OBJECTIVES AND METHODS:A total of 97 Egyptian patients provided a single voided urine sample for ANG, CK-20 and cytology befo...

journal_title：Clinical biochemistry

authors： Eissa S,Kenawy G,Swellam M,El-Fadle AA,Abd El-Aal AA,El-Ahmady O

更新日期：2004-09-01 00:00:00

abstract：:1. We compare the Roche ion-exchange column chromatography and the Merck antibody inhibition reaction for CK-MB fractionation in 51 sera. Measurements of total CK and CK-MB activities must be done under the same conditions for each method in order to correlate the results. 2. A decisional value must be used for the in...

journal_title：Clinical biochemistry

authors： Desjarlais F,Daigneault R

更新日期：1979-08-01 00:00:00

abstract：OBJECTIVE:We used single-strand conformational polymorphism (SSCP) to screen for mutations at nucleotides 833 and 919 of the cystathionine beta-synthase (CBS) gene in 13 patients with homocystinuria and 11 of their relatives. METHODS:Exon 8 of genomic DNA was selectively amplified by PCR using primers derived from int...

journal_title：Clinical biochemistry

authors： Tsai MY,Hanson NQ,Bignell MK,Schwichtenberg KA

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVES:The fibroblast growth factor receptor 3 gene (FGFR3) plays a critical role in cartilage growth-plate differentiation and bony development. It has been shown that 97% of patients with achondroplasia have a G to A transition mutation at position 1138 (c.1138 G>A) of codon 380 of the FGFR3 gene. DESIGN AND MET...

journal_title：Clinical biochemistry

authors： Hung CC,Lee CN,Chang CH,Jong YJ,Chen CP,Hsieh WS,Su YN,Lin WL

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVES:Breast cancer is the most common malignancy among Egyptian women. The aim of this study is to evaluate the role of both telomerase and TPS estimation in assessment of breast cancer. METHODS:The study included 40 patients with breast cancer, and 20 patients with benign breast diseases. Telomerase activity in...

journal_title：Clinical biochemistry

authors： Kassim SK,Fawzy H,El Rassad MM,Khalil FK,Khalifa A

更新日期：2001-09-01 00:00:00

abstract：:The Laser Nephelometer PDQTM (Hyland Division, Travenol Laboratories Inc.) and the Abbott Bichromatic Analyser 100 (Abbott Laboratories) were compared with a radial immunodiffusion method. Seventy-eight serum specimens collected during routine blood testing were aliquoted and quantitated by the three procedures descri...

journal_title：Clinical biochemistry

authors： Bruver RM,Salkie ML

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:Disease-independent sources of biomarker variability include pre-analytical, analytical and biological variance. The aim of the present study was to evaluate whether the pre-analytical phase has any impact on the emerging heart disease TWEAK and HMGB1 protein markers and miRNA biomarkers, and whether peptido...

journal_title：Clinical biochemistry

authors： Basso D,Padoan A,Laufer T,Aneloni V,Moz S,Schroers H,Pelloso M,Saiz A,Krapp M,Fogar P,Cornoldi P,Zambon CF,Rossi E,La Malfa M,Marotti A,Brefort T,Weis TM,Katus HA,Plebani M

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:To investigate the activities of the main antioxidative enzymes and oxidative stress in women with depressive disorder (DD). METHODS:In 35 drug-naive women with DD and 35 age matched healthy women enzymes superoxide dismutase (CuZnSOD), catalase (CAT), glutathione peroxidase (GPX1), glutathione reductase (G...

journal_title：Clinical biochemistry

authors： Kodydková J,Vávrová L,Zeman M,Jirák R,Macásek J,Stanková B,Tvrzická E,Zák A

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:Living kidney donors have been part of a successful kidney transplant programme in Norway for almost 50 years. Glomerular filtration rates (GFRs) have tended to remain stable at about 70% of pre-donation levels. Plasma total homocysteine (Hcy) has an inverse relationship to kidney function, and previous repor...

journal_title：Clinical biochemistry

authors： Apeland T,Holdaas H,Mansoor MA

更新日期：2014-04-01 00:00:00

abstract：:High-sensitivity cardiac troponin (hs-cTn) assays have been used clinically by thousands of physicians in many countries throughout the world since their clinical introduction seven years ago. In the early diagnosis of myocardial infarction (MI), beyond doubt the most important indication of hs-cTn assays, these simpl...

journal_title：Clinical biochemistry

authors： Twerenbold R,Boeddinghaus J,Nestelberger T,Wildi K,Rubini Gimenez M,Badertscher P,Mueller C

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:The glutathione S-transferases (GSTs) play a critical role in protecting the colorectal mucosa. We investigated the efficacy of using the GSTs activity of plasma as a biomarker of risk for colorectal cancer. METHODS:GSTs activity was measured in the plasma of control individuals (n=39) and in the plasma, tu...

journal_title：Clinical biochemistry

authors： Nomani H,Ghobadloo SM,Yaghmaei B,Rezvanie NA,Yaghmaei K

更新日期：2005-07-01 00:00:00

abstract：CONTEXT:Knee arthroplasty surgery is significant trauma, leading to an activated immune system causing inflammation and oxidative stress. Many current biomarkers are invasive, costly, and often slow to analyse, limiting their use for rapid inflammatory measurements. OBJECTIVES:We have examined the use of urinary neopt...

journal_title：Clinical biochemistry

authors： Baxter-Parker G,Roffe L,Cross S,Frampton C,Hooper GJ,Gieseg SP

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:To compare the analysis of urinary albumin from diabetic patients by four conventional immunoassays including radioimmunoassay (RIA), immunonephelometry (IN), and two different methods of immunoturbidimetry (IT), as well as by high-performance liquid chromatography (HPLC). DESIGN AND METHODS:Urines were col...

journal_title：Clinical biochemistry

authors： Comper WD,Jerums G,Osicka TM

更新日期：2004-02-01 00:00:00

abstract：AIMS:There is increasing interest in using fructosamine measurements in screening for or managing diabetes, yet uncertainty remains as to whether these measurements should be corrected for variation in serum protein concentrations. METHODS:We considered all sets of simultaneous measurements of fructosamine, albumin, t...

journal_title：Clinical biochemistry

authors： Rodríguez-Segade S,Rodríguez J,Camiña F

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:We evaluated the erythrocyte lipid susceptibility to oxidation and erythrocyte antioxidant status in patients with myocardial infarction (MI). DESIGN AND METHODS:Patients with MI were divided into two group according to the severity of the disease as severe (n = 30) or milder (n = 25). Malondialdehyde as a m...

journal_title：Clinical biochemistry

authors： Konukoğlu D,Akçay T,Erdem T

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVES:We emphasize the importance of routine follow-up of subnormal TSH concentrations with QC materials. DESIGN AND METHODS:The functional sensitivity (FS) of the ADVIA Centaur system TSH assay was assessed. We report the values yielded for QC materials in two clinical laboratories. RESULTS:The FS was <0.02 mIU...

journal_title：Clinical biochemistry

authors： Reix N,Massart C,Gasser F,Heurtault B,Agin A

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The availability of reference intervals is essential for physicians to interpret laboratory results. Most of our laboratory reference intervals are derived from data on the foreign population. We have studied the reference intervals of 24 common laboratory biochemical tests in an apparently healthy adult Han...

journal_title：Clinical biochemistry

authors： Yang S,Qiao R,Li Z,Wu Y,Yao B,Wang H,Cui L,Yang Y,Zhang J

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:Recently cortisol level in hair is supposed to be a good biomarker of chronic stress. We had developed a new method based on HPLC-FLU for identification of cortisol in human hair and measured cortisol distribution of each 1-cm segment along hair shaft. DESIGN AND METHODS:Hair sample was pulverized and incuba...

journal_title：Clinical biochemistry

authors： Gao W,Xie Q,Jin J,Qiao T,Wang H,Chen L,Deng H,Lu Z

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Cardiac troponins (cTn) are essential in the diagnostic assessment of non-ST-segment-elevation acute coronary syndrome (NSTE-ACS). Elevated concentrations of cTnT and cTnI predict cardiovascular events in non-acute settings, but the individual troponin isotype association with long-term mortality in patients...

journal_title：Clinical biochemistry

authors： Tveit SH,Myhre PL,Hoff NJS,Le TM,Seljeflot I,Røysland R,Høiseth AD,Røsjø H,Omland T

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:The detection of possible correlation between ribosomal protein RPS27A and multifunctional YB-1 expression in hepatocellular carcinoma (HCC). DESIGN AND METHODS:Tissue microarray slides containing totally 80 cores with 19 tissues of HCC, 1 tissue of hepatocholangiocarcinoma, 10 tissues of liver cirrhosis and...

journal_title：Clinical biochemistry

authors： Gunasekaran VP,Ganeshan M

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:: To test if circulating forms of the soluble urokinase-type plasminogen activator receptor (suPAR) are potential biomarkers of plaque vulnerability. DESIGN AND METHODS:: Plasma concentrations of suPAR(I-III), suPAR(II-III) and uPAR(I) were measured by time-resolved fluorescence immunoassays in Caucasian pa...

journal_title：Clinical biochemistry

authors： Olson FJ,Thurison T,Ryndel M,Høyer-Hansen G,Fagerberg B

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To quantify pepsinogen C (PEPC) and prostaglandin D synthase (PGDS) in breast cyst fluid and examine if these two parameters can be used for breast cyst type classification. DESIGN AND METHODS:We quantified PEPC and PGDS in 92 and 50 breast cyst fluids, respectively, using previously established immunofluoro...

journal_title：Clinical biochemistry

authors： Borchert GH,Melegos DN,Yu H,Giai M,Roagna R,Ponzone R,Sgro L,Diamandis EP

更新日期：1999-02-01 00:00:00

abstract：:The ES 300 system, a fully automated multichannel immunoassay analyzer, was evaluated simultaneously for 9 weeks in four major centers. Precision, accuracy, carryover, comparison to in-house methods, and interferences were assessed for the following 17 tests: T4, T3, FT4, TSH, TBK, TBG, LH, FSH, prolactin, HCG, digoxi...

journal_title：Clinical biochemistry

authors： D'Costa M,Feld R,Laxdal V,Trundle D,Collinsworth WL

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVES:Biallelic mutations in the ARG1 gene result in an uncommon autosomal recessive inborn defect of the urea cycle known as hyperargininemia (OMIM #207800). ARG1 splicing mutations are not reported often, and they are probably related to a more severe phenotype than missense mutations. In this article, we descri...

journal_title：Clinical biochemistry

authors： Villegas-Ruiz V,Campos-Garcia FJ,Contreras-Capetillo S,Moreno-Graciano CM,Maldonado-Solis FA,Maldonado-Solis MA,Zenteno JC

更新日期：2015-12-01 00:00:00

abstract：:Increased hemoglobin A1 (HbA1) occurs in diabetes mellitus as a direct consequence of hyperglycemia, which causes postsynthetic modification of hemoglobin proportional to blood glucose concentration. Glycosylation of hemoglobin is demonstrable also in vitro, not only by glucose, but with other reducing sugars such as ...

journal_title：Clinical biochemistry

authors： Powell HC,Ivor LP,Costello ML,Wolf PL

更新日期：1982-06-01 00:00:00