The quality of randomized controlled trials in major anesthesiology journals.

abstract：BACKGROUND:Percutaneous cannulation of the femoral vein, in the pediatric age group, can be technically challenging, especially when performed by residents in training. We examined whether the use of real-time ultrasound guidance is superior to a landmark technique for femoral vein catheterization in children undergoin...

journal_title：Anesthesia and analgesia

authors： Aouad MT,Kanazi GE,Abdallah FW,Moukaddem FH,Turbay MJ,Obeid MY,Siddik-Sayyid SM

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Different drugs have been used to enhance postoperative neuraxial opioid analgesia and reduce adverse effects. METHODS:We randomized 60 patients into 2 groups to receive either 2 mL saline or 0.1 mg/kg dexamethasone IV before the administration of intrathecal anesthesia (15 mg and meperidine 15 mg). After s...

journal_title：Anesthesia and analgesia

authors： Movafegh A,Soroush AR,Navi A,Sadeghi M,Esfehani F,Akbarian-Tefaghi N

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Both propofol infusions with oxygen delivered through nasal cannula and isoflurane/N2O (nitrous oxide) delivered via a laryngeal mask airway (LMA) are used to provide anesthesia for children undergoing magnetic resonance imaging scans. We compared the incidence of adverse events and perioperative physiologic...

journal_title：Anesthesia and analgesia

authors： Heard C,Harutunians M,Houck J,Joshi P,Johnson K,Lerman J

更新日期：2015-01-01 00:00:00

abstract：:The contribution of the lung to the clearance of exogenous dopamine after cardiopulmonary bypass (CPB) was analyzed quantitatively in humans and compared with the contribution of the lung before CPB. The pulmonary and arterial plasma concentration of dopamine and the pulmonary plasma flow were measured simultaneously ...

journal_title：Anesthesia and analgesia

authors： Hayashi Y,Sumikawa K,Yamatodani A,Kamibayashi T,Mammoto T,Kuro M

更新日期：1993-01-01 00:00:00

abstract：:Clinical and metabolic responses to three types of premedication were studied in ASA physical status I patients given any one of the following: (a) 0.5 mg of atropine and 50 mg of meperidine given intramuscularly plus an oral placebo tablet (n = 14), (b) 10 mg of oral diazepam and an intramuscular placebo (2 mL NaCl, ...

journal_title：Anesthesia and analgesia

authors： Kirvelä OA,Kanto JH

更新日期：1991-07-01 00:00:00

abstract：:We examined the percentage of tactile detection of fade in response to train-of-four (TOF), double burst stimulation3,3 (DBS3,3), or DBS3,2 at the index finger compared with that at the thumb during continuous infusion of vecuronium. One hundred five adult patients were studied. At TOF ratios (T4/T1) of 0.41-0.70, fad...

journal_title：Anesthesia and analgesia

authors： Saitoh Y,Nakazawa K,Makita K,Tanaka H,Amaha K

更新日期：1997-06-01 00:00:00

abstract：:The low solubility of sevoflurane in blood suggests that this agent should enter and leave the body more rapidly than isoflurane. However, the closeness of sevoflurane and isoflurane tissue/blood partition coefficients suggests that the rates of equilibration with and elimination from tissues should be similar. We tes...

journal_title：Anesthesia and analgesia

authors： Yasuda N,Lockhart SH,Eger EI 2nd,Weiskopf RB,Liu J,Laster M,Taheri S,Peterson NA

更新日期：1991-03-01 00:00:00

abstract：:We conducted this prospective, randomized study to compare the analgesic effect of femoral nerve block and IV fentanyl administration when given to facilitate the sitting position for spinal anesthesia in patients undergoing surgery for femoral shaft fracture. Five minutes before the placement of spinal block, group F...

journal_title：Anesthesia and analgesia

authors： Sia S,Pelusio F,Barbagli R,Rivituso C

更新日期：2004-10-01 00:00:00

abstract：:Although the pathogenesis of acute renal injury after cardiac surgery is multifactorial, atherosclerosis of the ascending aorta and embolic burden are strong independent predictors. Use of the Symmetry aortic connector device (ACD) for proximal anastomosis of coronary grafts may reduce ascending aortic atheroembolism....

journal_title：Anesthesia and analgesia

authors： Fischer SS,Phillips-Bute B,Swaminathan M,Milano C,Stafford-Smith M

更新日期：2006-01-01 00:00:00

abstract：UNLABELLED:Diabetic patients are at increased risk of wound infection after major surgery, but the effect of perioperative glucose control on postoperative wound infection rates after surgery is uncertain. We tested the effect of an insulin infusion on perioperative neutrophil function in diabetic patients scheduled fo...

journal_title：Anesthesia and analgesia

authors： Rassias AJ,Marrin CA,Arruda J,Whalen PK,Beach M,Yeager MP

更新日期：1999-05-01 00:00:00

abstract：:Ocular microtremor (OMT) is a fine physiologic tremor of the eye related to neuronal activity in the reticular formation of the brainstem. The frequency of OMT is suppressed by propofol and sevoflurane and predicts the response to command at emergence from anesthesia. Previous studies have relied on post hoc computer ...

journal_title：Anesthesia and analgesia

authors： Heaney M,Kevin LG,Manara AR,Clayton TJ,Timmons SD,Angel JJ,Smith KR,Ibata B,Bolger C,Cunningham AJ

更新日期：2004-09-01 00:00:00

abstract：:This study was designed to measure the disappearance rate of indocyanine green (ICG) as an indicator of hepatic blood flow in elderly patients undergoing internal fixation of fractured neck of femur. All patients were aged 60-90 yr and were randomized to receive either spinal (n = 10) or isoflurane (n = 10) anesthesia...

journal_title：Anesthesia and analgesia

authors： Darling JR,Murray JM,Hainsworth AM,Trinick TR

更新日期：1994-04-01 00:00:00

abstract：UNLABELLED:Ketamine, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, has psychotomimetic activity. NMDA receptor antagonists cause morphological damage in the posterior cingulate cortex, which may be the brain region responsible for their psychotomimetic effects. Benzodiazepines are effective in preve...

journal_title：Anesthesia and analgesia

authors： Nagata A,Nakao S,Miyamoto E,Inada T,Tooyama I,Kimura H,Shingu K

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Heart rate variability might predict arrhythmias after coronary artery bypass grafting. METHODS:Off-line processing of 10-min electrocardiogram recordings of consecutive patients provided R-R intervals for time domain, frequency domain, Poincaré, and point correlation analyses and subsequent association wit...

journal_title：Anesthesia and analgesia

authors： Chamchad D,Djaiani G,Jung HJ,Nakhamchik L,Carroll J,Horrow JC

更新日期：2006-11-01 00:00:00

abstract：:Interscalene brachial plexus anesthesia for shoulder surgery routinely includes sensory anesthesia of the fourth and fifth cervical nerves. The authors reasoned that some degree of diaphragm paralysis should result from interscalene blocks that produce surgical C3-C5 sensory anesthesia. In this investigation, ultrason...

journal_title：Anesthesia and analgesia

authors： Urmey WF,Talts KH,Sharrock NE

更新日期：1991-04-01 00:00:00

abstract：:Malignant hyperthermia syndrome associated with various anesthetic agents has been well documented, but none has been reported with enflurane (Ethrane). This particular case is the first involving exposure for the second time to enflurane anesthesia after a six-month interval in which malignant hyperthermia resulted. ...

journal_title：Anesthesia and analgesia

authors： Pan TH,Wollack AR,DeMarco JA

更新日期：1975-01-01 00:00:00

abstract：:This research determined the safety and efficacy of two small-dose infusions of dexmedetomidine by evaluating sedation, analgesia, cognition, and cardiorespiratory function. Seven healthy young volunteers provided informed consent and participated on three occasions with random assignment to drug or placebo. Heart rat...

journal_title：Anesthesia and analgesia

authors： Hall JE,Uhrich TD,Barney JA,Arain SR,Ebert TJ

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Hyperkalemia poses serious hazards to patients undergoing orthotopic liver transplantation (OLT), and its predictors have not been thoroughly examined. METHODS:We retrospectively studied 1124 consecutive adult patients who underwent OLT. Hyperkalemia was defined as serum K+ > or =5.5 mmol/L. A total of 47 r...

journal_title：Anesthesia and analgesia

authors： Xia VW,Ghobrial RM,Du B,Chen T,Hu KQ,Hiatt JR,Busuttil RW,Steadman RH

更新日期：2007-09-01 00:00:00

abstract：:In recent years, there have been escalating concerns related to the opioid epidemic. With a steadily increasing opioid supply, it is critical to provide proper education to patients who are prescribed these medications. Education should be emphasized as a means of ensuring safe use and potentially as a strategy for cu...

journal_title：Anesthesia and analgesia

authors： Lee BH,Wu CL

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Many animal models can be used to study the underlying pathophysiological mechanisms of neuropathic pain. Most of these models rely on a partial denervation of the limb of the animal by ligating a selected nerve. In this study, we performed nerve lesions on three peripheral nerves supplying the plantar side ...

journal_title：Anesthesia and analgesia

authors： Van Remoortere MP,Meert TF,Vissers KC,Coppenolle H,Adriaensen H

更新日期：2007-05-01 00:00:00

abstract：:The hemodynamic effects of esmolol were studied in 40 patients scheduled for elective coronary artery surgery to determine whether the administration of esmolol in chronically beta-blocked patients would result in additional attenuation of sympathetically mediated hemodynamic stress responses to noxious stimuli. Patie...

journal_title：Anesthesia and analgesia

authors： de Bruijn NP,Croughwell N,Reves JG

更新日期：1987-02-01 00:00:00

abstract：:A 62-yr-old man presented for a microdirect laryngoscopy and vocal cord fat grafting under jet ventilation. After a prolonged laryngoscopy, the patient developed hypercapnea and upper airway obstruction secondary to traumatic epiglottitis. The placement of a laryngeal mask airway provided ventilation and allowed for d...

journal_title：Anesthesia and analgesia

authors： Kidani DC,Shah NK

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:The primary objective of this study was to compare the characteristics of culture-positive and culture-negative status in septic patients. We also determined whether culture status is associated with mortality and whether unique variables are associated with mortality in culture-positive and culture-negative...

journal_title：Anesthesia and analgesia

authors： Sigakis MJG,Jewell E,Maile MD,Cinti SK,Bateman BT,Engoren M

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Drug-induced sleep endoscopy (DISE) uses sedative-hypnotics to induce moderate obstruction in sleep apnea patients, thereby facilitating anatomic assessment of obstructive physiology. Implementation of DISE with propofol requires a dosing strategy that reliably and efficiently produces obstruction while mini...

journal_title：Anesthesia and analgesia

authors： Atkins JH,Mandel JE,Rosanova G

更新日期：2014-10-01 00:00:00

abstract：:Contulakin-G is a novel conopeptide with an incompletely defined mechanism of action. To assess nociceptive activity we delivered Contulakin-G as a bolus intrathecally (0.03, 0.1, 0.3, 3 nmol) or epidurally (10, 30, 89 nmol) in rats. Intrathecal Contulakin G significantly decreased Phase II and, to a lesser degree, Ph...

journal_title：Anesthesia and analgesia

authors： Allen JW,Hofer K,McCumber D,Wagstaff JD,Layer RT,McCabe RT,Yaksh TL

更新日期：2007-06-01 00:00:00

abstract：UNLABELLED:We sought to determine whether acute experimental allergic encephalomyelitis (EAE) alters the incorporation of epidurally administered [(3)H]-D-mannitol and [(14)C]-carboxyl-inulin into the lumbar spinal cord in rabbits. Acute EAE is an experimental model for demyelinating spinal cord diseases such as multip...

journal_title：Anesthesia and analgesia

authors： Naidu KA,Fu ES,Prockop LD

更新日期：2002-01-01 00:00:00

abstract：UNLABELLED:We investigated the direct effects of midazolam and diazepam on cardiac excitation-contraction coupling in adult rat ventricular myocytes. Freshly isolated rat ventricular myocytes were loaded with fura-2/AM and field-stimulated at 28 degrees C. Intracellular Ca(2+) transients (340:380 ratio) and myocyte sho...

journal_title：Anesthesia and analgesia

authors： Kanaya N,Murray PA,Damron DS

更新日期：2002-12-01 00:00:00

abstract：UNLABELLED:Flurbiprofen, a nonsteroidal antiinflammatory drug (NSAID), has been used to treat rheumatic and osteoarthritic pain and to reduce postoperative pain. Although other NSAIDs, such as indomethacin, reduce cerebral blood flow (CBF), the effect of flurbiprofen on CBF is unknown. In the present study, we investig...

journal_title：Anesthesia and analgesia

authors： Yoshitani K,Kawaguchi M,Tatsumi K,Sasaoka N,Kurumatani N,Furuya H

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:In this study, we compared the effectiveness of direct laryngoscopy (DL) and the GlideScope videolaryngoscope (GVL) for nasotracheal intubation, as judged by the time to intubation (TTI-the primary outcome) and the ease of intubation. METHODS:Seventy patients requiring nasotracheal intubation for elective s...

journal_title：Anesthesia and analgesia

authors： Jones PM,Armstrong KP,Armstrong PM,Cherry RA,Harle CC,Hoogstra J,Turkstra TP

更新日期：2008-07-01 00:00:00

abstract：:Combinations of alpha 2 agonists and opiates are used in the clinical management of pain to harness their potential synergistic interaction for analgesia while limiting their side-effects. To better predict the clinical consequences of this combination, we studied the behavioral effects of dexmedetomidine, a highly se...

journal_title：Anesthesia and analgesia

authors： Hayashi Y,Guo TZ,Maze M

更新日期：1996-09-01 00:00:00