Sleep disordered breathing and cognitive function in a retirement village population.

Abstract:

:Sleep disordered breathing (SDB) may be associated with cognitive dysfunction in non-demented elderly people. A random sample of 96 retirement village residents were given both neuropsychological assessment and overnight sleep monitoring with a portable microprocessor based system (Vitalog PMS-8). Respiratory disturbance index (RDI) was calculated as the number of apnoeas and hypopnoeas per hour of sleep. RDI was not associated with 'memory', 'verbal', and 'motor' factors identified from the analysis of cognitive tests, but was associated with the 'cerebral efficiency' factor (R2 = 0.21, p less than 0.0001). Seventy-three subjects had repeat neuropsychological tests, median time to follow-up being 17 months. Baseline RDI did not predict changes in scores on the two factors identified from the second analysis. We conclude that mild to moderate disturbance of breathing during sleep is not associated with cognitive dysfunction in non-demented subjects.

journal_name

Age Ageing

journal_title

Age and ageing

authors

Hayward L,Mant A,Eyland A,Hewitt H,Purcell C,Turner J,Goode E,Le Count A,Pond D,Saunders N

doi

10.1093/ageing/21.2.121

subject

Has Abstract

pub_date

1992-03-01 00:00:00

pages

121-8

issue

2

eissn

0002-0729

issn

1468-2834

journal_volume

21

pub_type

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