Abstract:
:Sleep disordered breathing (SDB) may be associated with cognitive dysfunction in non-demented elderly people. A random sample of 96 retirement village residents were given both neuropsychological assessment and overnight sleep monitoring with a portable microprocessor based system (Vitalog PMS-8). Respiratory disturbance index (RDI) was calculated as the number of apnoeas and hypopnoeas per hour of sleep. RDI was not associated with 'memory', 'verbal', and 'motor' factors identified from the analysis of cognitive tests, but was associated with the 'cerebral efficiency' factor (R2 = 0.21, p less than 0.0001). Seventy-three subjects had repeat neuropsychological tests, median time to follow-up being 17 months. Baseline RDI did not predict changes in scores on the two factors identified from the second analysis. We conclude that mild to moderate disturbance of breathing during sleep is not associated with cognitive dysfunction in non-demented subjects.
journal_name
Age Ageingjournal_title
Age and ageingauthors
Hayward L,Mant A,Eyland A,Hewitt H,Purcell C,Turner J,Goode E,Le Count A,Pond D,Saunders Ndoi
10.1093/ageing/21.2.121subject
Has Abstractpub_date
1992-03-01 00:00:00pages
121-8issue
2eissn
0002-0729issn
1468-2834journal_volume
21pub_type
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