Abstract:
BACKGROUND:up to 25% of older people in the USA and other Western countries are anaemic by World Health Organization (WHO) criteria. The objective of this study was to examine the long-term relationships of haemoglobin concentration with all-cause and cause-specific mortality in a community-based sample of Australian adults surveyed in 1978. METHODS:a community survey of 2,194 adults aged 40+ years in Busselton, Western Australia in 1978 with mortality follow-up to 2001. Cox regression models were used to investigate the relationships of haemoglobin as a continuous measure and anaemia by WHO criteria (women <12 g/dl (7.5 mmol/l); men <13 g/dl (8.1 mmol/l)) with all-cause, cardiovascular and cancer mortality. RESULTS:anaemia was predominantly mild (>10 g/dl) and normocytic. There was an increased risk of death from all causes and from cancer for men with low haemoglobin. Cancers were predominantly of the prostate and genito-urinary organs, and to a lesser extent the gastrointestinal tract. There was no increased risk of all cause or cancer death in women. CONCLUSION:mild, normocytic anaemia is associated with survival reductions in middle-aged and older men, where it often occurs with prostate, gastrointestinal and other cancers, and should be investigated to exclude treatable causes.
journal_name
Age Ageingjournal_title
Age and ageingauthors
Chalmers KA,Knuiman MW,Divitini ML,Bruce DG,Olynyk JK,Milward EAdoi
10.1093/ageing/afs150subject
Has Abstractpub_date
2012-11-01 00:00:00pages
759-64issue
6eissn
0002-0729issn
1468-2834pii
afs150journal_volume
41pub_type
杂志文章相关文献
AGE AND AGEING文献大全abstract::Myasthenia gravis is probably commoner than previously suspected, the annual incidence being nearer 9-10/million than earlier figures of 2-4/million. The current study found an annual incidence in Croyden of 9.1 per million (95% confidence limits 5.7-13.8 per million). Of the 22 patients (59%) seen in Croyden with new...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/25.1.56
更新日期:1996-01-01 00:00:00
abstract::Cellular immune function declines with age and is implicated in the increased incidence of cancer, and morbidity and mortality associated with infections in elderly people. Elderly people are at risk of nutritional depletion, including of zinc, and zinc is known to influence immunity. The present study assessed zinc s...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/20.5.345
更新日期:1991-09-01 00:00:00
abstract::We evaluated the effect of impaired hearing and vision on balance in a sample of 977 elderly people residing in the community. Of the sample, 21% reported balance problems, 27% vision problems, and 30% hearing problems. The increased relative risk for balance problems was 1.7 for each 10-year age increment. Women were...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/18.1.31
更新日期:1989-01-01 00:00:00
abstract::Alcohol consumption constitutes a substantial burden of disease. Older people are being admitted to hospital for alcohol problems in increasing numbers. A recent systematic review reports cautious supportive evidence for primary prevention interventions in reducing excessive alcohol consumption in older drinkers, but ...
journal_title:Age and ageing
pub_type: 评论,杂志文章
doi:10.1093/ageing/afx191
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVES:To determine the presentation, course and duration of delirium in hospitalized older people. DESIGN:Observational cohort study. SETTING:Inpatient surgical and medical wards at a university hospital. PARTICIPANTS:432 people over the age of 65. MEASUREMENTS:All participants were screened daily for confusio...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/26.3.169
更新日期:1997-05-01 00:00:00
abstract:PURPOSE:health-related quality of life (HRQOL) is an important psycho-social characteristic which may impact an individual's ability to manage their chronic disease. We examined the association between HRQOL and antihypertensive medication adherence in older adults. METHODS:participants were part of a cohort study of ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afq040
更新日期:2010-07-01 00:00:00
abstract::Of 60 patients referred for geriatric assessment with clinically significant hypochromic anaemia, in the absence of frank bleeding, 44 underwent upper gastrointestinal and 27 lower gastrointestinal investigations. The probability of identifying a potential cause at upper gastrointestinal endoscopy was three times that...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/16.6.399
更新日期:1987-11-01 00:00:00
abstract:INTRODUCTION:observational studies do not always find positive associations between physical activity and muscle strength despite intervention studies consistently showing that exercise improves strength in older adults. In previous analyses of the MRC National Survey of Health and Development (NSHD), the 1946 British ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/aft124
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:to analyse socio-demographic differences in the onset and progression of disability. DESIGN:analysis of a cohort of people aged 55-69 in 1988-9 and in 1994. SUBJECTS:a representative sample of 3543 adults. METHODS:we measured severity of disability at baseline and follow-up. We analysed variations in inci...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/29.2.149
更新日期:2000-03-01 00:00:00
abstract:Background:pain is prevalent in frail older adults; however, the association of pain and frailty has not been evaluated yet by a systematic assessment of prospective longitudinal studies. Objective:we aimed to assess the association of persistent pain as a risk factor for frailty incidence, using data from longitudina...
journal_title:Age and ageing
pub_type: 杂志文章,meta分析
doi:10.1093/ageing/afy104
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:we evaluated a specialist community-based dementia service to establish whether high quality care was being delivered and the conditions for doing so. The service was in an urban part of Rushcliffe Primary Care Trust, Nottinghamshire, United Kingdom. The service comprised an assessment team of an occupationa...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afl161
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:in the UK, two-thirds of patients in general hospitals are older than 70, of whom half have dementia or delirium or both. Our objective was to explore doctors, nurses and allied health professionals' perceptions of their preparation to care for confused older patients on general hospital wards....
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/aft171
更新日期:2014-07-01 00:00:00
abstract:Background:screening for cognitive impairment in Emergency Department (ED) requires short, reliable tools. Objective:to validate the 4AT and 6-Item Cognitive Impairment Test (6-CIT) for ED dementia and delirium screening. Design:diagnostic accuracy study. Setting/subjects:attendees aged ≥70 years in a tertiary care ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afx149
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:thickened fluids are commonly advised to minimise the risk of aspiration in people with dysphagia, although many do not comply with this treatment. In health economics, utilities are values that reflect an individual's preferences for different health states. We examined the healthcare utilities, elicited us...
journal_title:Age and ageing
pub_type: 杂志文章,随机对照试验
doi:10.1093/ageing/afv194
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The very old are expected to become a growing part of the stroke population in the industrialised part of the world. The aims of this study were to evaluate clinical characteristics of patients aged 85 years or more at stroke onset and to investigate very old age as an independent predictor of sh...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afh052
更新日期:2004-03-01 00:00:00
abstract:METHOD:We investigated the association of total serum cholesterol concentrations and subsequent overall and coronary mortality in 304 patients aged > or =65 discharged from hospital after acute myocardial infarction. RESULTS:There was no association between total cholesterol concentrations and mortality due to either ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/28.3.313
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:Visuo-spatial neglect (VSN) after stroke is associated with a poor prognosis for rehabilitation. The co-existence of a visual field deficit (VFD) with VSN may be associated with impaired visuo-spatial functioning and thereby poor functional outcome. OBJECTIVE:To determine whether the presence of a VFD (i) e...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/28.3.257
更新日期:1999-05-01 00:00:00
abstract::This paper describes how a sample of elderly people were identified from the electoral register using an initial postal screen, and reports a technique that was used to increase the response to the screen. ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/16.2.119
更新日期:1987-03-01 00:00:00
abstract::Interest in, and concern about, the abuse of elderly people is growing rapidly. A study of the literature shows little research in the UK, but valuable indicators about risk factors and interventions from North America. One of the major problems has been definition and this paper distinguishes between different kinds ...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/22.1.65
更新日期:1993-01-01 00:00:00
abstract::The change in mental and physical functioning over 5 years for 594 survivors of a community survey of the elderly is described. An increase in cognitive impairment, physical disability and incontinence over the period was found with increasing age. Women in the two oldest age groups had a significantly greater increas...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/18.2.77
更新日期:1989-03-01 00:00:00
abstract::One hundred and sixty centenarians were discovered and followed up for 7 years (1982-88) in Shanghai. The proportion of centenarians in the population was non-significantly greater in the urban than in the rural area and centenarians were in general increasing in both areas over the years. The factors promoting longev...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/22.1.16
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:to evaluate the relationship between serum levels of the soluble Receptor for Advanced Glycation End-products (sRAGE) and mortality in frail and non-frail older adults. METHODS:we studied 691 subjects (141 frail and 550 non-frail) with a median age of 75 years from two population-based cohorts, the Toledo St...
journal_title:Age and ageing
pub_type: 杂志文章,多中心研究
doi:10.1093/ageing/afz073
更新日期:2019-09-01 00:00:00
abstract::Joint geriatric/psychiatric wards are a potential solution to improving care of older patients with both psychiatric and medical illnesses in acute hospitals. A literature search using Medline, PsycINFO, Embase and CINAHL between 1980 and 2010 was carried out for information about joint wards for older people. Thirtee...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/afr080
更新日期:2011-09-01 00:00:00
abstract::Brucellosis is the most commonly reported zoonosis. Nervous system participation can occur at any stage of the disease either in acute or subacute or chronic form. Isolated nervous system involvement or neurobrucellosis is a relatively rare form of the disease. We describe an unusual case of an older patient with deme...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afz020
更新日期:2019-07-01 00:00:00
abstract:Background:measuring the complex needs of care home residents is crucial for resource allocation. Hospital patient administration systems (PAS) may not accurately identify admissions from care homes. Objective:to develop and validate an accurate, practical method of identifying care home resident hospital admission us...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afx182
更新日期:2018-05-01 00:00:00
abstract:INTRODUCTION:increasing public costs for the care of the elderly have created fundamental changes that are redefining the basic principles of health care funding. In the past, overall institutional funding was predominantly tied to spending. In view of the limitations of this approach to funding long-term care faciliti...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/32.1.60
更新日期:2003-01-01 00:00:00
abstract:AIM:to examine the degree of medical treatment wanted by nursing home residents, their relatives and staff members should the resident develop a serious and life-threatening disease and to analyse the degree of agreement between the wishes of these parties. DESIGN:an epidemiological, descriptive cross-sectional study....
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/26.2.133
更新日期:1997-03-01 00:00:00
abstract::Data on National Health Service (NHS) dental care utilization by the elderly are analysed to consider the distribution of dental care according to the charge status of the patient. Considerable and significant differences are observed in the type and amount of dental care provided to elderly patients exempt and not ex...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/18.2.136
更新日期:1989-03-01 00:00:00
abstract::Faecal incontinence occurring at least once weekly was found in 10.3% of residents in 30 residential homes for the elderly. Fifty-two randomly-selected incontinent residents were prescribed treatment and the outcome was compared with 30 incontinent residents acting as controls. The vast majority of all incontinent res...
journal_title:Age and ageing
pub_type: 临床试验,杂志文章
doi:10.1093/ageing/15.1.41
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:The reason why elderly human hips tend to break in one of two anatomical regions is uncertain. Nutritional factors may affect the site of fracture. OBJECTIVE:To assess possible nutritional differences in patients with proximal femoral fractures. DESIGN:Prospective observational cohort study. SETTING:Unive...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/28.5.458
更新日期:1999-09-01 00:00:00