Abstract:
:The synthesis of novel C6-aryl substituted derivatives of 3-(dimethylamino)chroman is described. The novel derivatives display 5-HT(7) receptor affinities that varies from nM to muM, indicating that this small set of derivatives constitute a novel and interesting starting point for further structure-serotonin 5-HT(7) activity relationship (SAR) studies.
journal_name
Bioorg Med Chem Lettjournal_title
Bioorganic & medicinal chemistry lettersauthors
Holmberg P,Tedenborg L,Rosqvist S,Johansson AMdoi
10.1016/j.bmcl.2004.11.013subject
Has Abstractpub_date
2005-02-01 00:00:00pages
747-50issue
3eissn
0960-894Xissn
1464-3405pii
S0960-894X(04)01349-6journal_volume
15pub_type
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