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Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: a structure-activity evaluation study.

Abstract：

:Gram positive (Bacillus cereus, B. subtilis), Gram negative (Pseudomonas aeruginosa, Escherichia coli) bacteria, and Candida albicans as a representative of fungi were used for screening the in vitro antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series bearing different substituents, synthesized by us using the palladium-catalyzed C-N coupling methodology. The minimal inhibitory concentration (MIC) and structure-activity relationships (SARs) were evaluated.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Ferreira IC,Calhelha RC,Estevinho LM,Queiroz MJ

doi

10.1016/j.bmcl.2004.09.038

subject

Has Abstract

pub_date

2004-12-06 00:00:00

pages

5831-3

issue

23

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(04)01150-3

journal_volume

14

pub_type

杂志文章

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