Abstract：
:The physical basis for electrical stimulation of excitable tissue, as used by electrophysiological researchers and clinicians in functional electrical stimulation, is presented with emphasis on the fundamental mechanisms of charge injection at the electrode/tissue interface. Faradaic and non-Faradaic charge transfer mechanisms are presented and contrasted. An electrical model of the electrode/tissue interface is given. The physical basis for the origin of electrode potentials is given. Various methods of controlling charge delivery during pulsing are presented. Electrochemical reversibility is discussed. Commonly used electrode materials and stimulation protocols are reviewed in terms of stimulation efficacy and safety. Principles of stimulation of excitable tissue are reviewed with emphasis on efficacy and safety. Mechanisms of damage to tissue and the electrode are reviewed.
journal_name
J Neurosci Methodsjournal_title
Journal of neuroscience methodsauthors
Merrill DR,Bikson M,Jefferys JGdoi
10.1016/j.jneumeth.2004.10.020subject
Has Abstractpub_date
2005-02-15 00:00:00pages
171-98issue
2eissn
0165-0270issn
1872-678Xpii
S0165-0270(04)00382-6journal_volume
141pub_type
杂志文章,评审abstract：:The aim of the study was to compare saccadic peak velocity (SPV) values measured with video based Fitness Impairment Tester (FIT) and electro-oculography (EOG) during prolonged wakefulness. We tested different numbers of saccades and two saccade paradigms to improve the EOG measurements for detecting fatigue. The SPVs...
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