Abstract：
:The factors that affect survival in patients with stage 4 neuroblastoma vary. Several prospective and retrospective studies have provided conflicting conclusions regarding the benefit of combining aggressive chemotherapy with complete surgical resection. We analyzed our experience to evaluate the effect of complete surgical resection of the primary tumor on survival when disseminated disease has been controlled by chemotherapy. We retrospectively reviewed the medical records of 44 consecutive children with neuroblastoma treated between 1990 and 2000. Twenty-six children with stage 4 disease were enrolled. Most were treated with surgical resection combined with chemotherapy. The survival rate was compared based on the timing (primary versus delayed until chemotherapy had been given) and results of surgery (complete tumor resection, microscopic residual disease, and gross residual disease). The mean survival (52.8 months) of children with delayed complete surgical resection (CSR) was statistically superior to that of those with microscopic residual (20.8 months, p = 0.0111) or gross residual tumor (12.2 months, p = 0.0141). In the CSR group, 1-, 2-, 3-, and 5-year survival rates were 88%, 77%, 77%, and 65%, respectively, vs. 80%, 40%, 20%, and 0% in the microscopic residual group. In conclusion, complete resection of the primary tumor with no residual disease was associated with improved survival in children with advanced neuroblastoma whose metastatic disease had been controlled by chemotherapy.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Koh CC,Sheu JC,Liang DC,Chen SH,Liu HCdoi
10.1007/s00383-004-1353-xsubject
Has Abstractpub_date
2005-02-01 00:00:00pages
69-72issue
2eissn
0179-0358issn
1437-9813journal_volume
21pub_type
杂志文章abstract：:The authors report two patients with extrahepatic portal hypertension and repeated massive bleeding from esophageal varices who underwent urgent distal splenorenal shunting (DSRS) after having proved refractory to medical treatment, endoscopic sclerotherapy, and ligation of esophageal varices. Their ages and weights w...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830100014
更新日期：2001-11-01 00:00:00
abstract：PURPOSE:This study's aim was to assess the use of intravesical injection of botulinum neurotoxin type A (BoNT-A) as a treatment of overactive bladder (OAB) in children. METHODS:A 6-year retrospective study of children who received BoNT-A for OAB was performed. Treatment outcome was classified as complete success (CS),...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-011-3039-5
更新日期：2012-03-01 00:00:00
abstract：:A neonate with a constellation of unusual congenital deformities associated with pulmonary agenesis is reported. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050603
更新日期：1999-07-01 00:00:00
abstract：PURPOSE:Congenital lung abnormalities are rare malformations increasingly detected early by prenatal ultrasound. Whether management of these frequently asymptomatic lesions should be surgical or conservative is an unresolved issue. The necessary prospective studies are limited by the absence of a widely accepted practi...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-017-4062-y
更新日期：2017-06-01 00:00:00
abstract：:We present the case of a 10-year-old girl with biliary atresia in whom focal nodular hyperplasia (FNH) of the liver occurred following successful "Kasai" hepatic portoenterostomy at the age of 2 months. Her jaundice completely disappeared a few weeks after the operation. A 4-cm diameter liver tumor in segment IV was f...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-2090-8
更新日期：2008-05-01 00:00:00
abstract：INTRODUCTION:Recent advances in laparoscopic surgery as well as increasing experience with these techniques have led to the selection of laparoscopic surgery for hemi/partial nephroureterectomy in children with a non/poorly functioning moiety in a duplex kidney. There is very little data on the long term follow-up of s...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-011-2883-7
更新日期：2011-07-01 00:00:00
abstract：PURPOSE:Determining the integrity of the pancreatic duct is important in high-grade pancreatic trauma to guide decision making for operative vs non-operative management. Computed tomography (CT) is generally an inadequate study for this purpose, and magnetic resonance cholangiopancreatography (MRCP) is sometimes obtain...
journal_title：Pediatric surgery international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00383-018-4309-2
更新日期：2018-09-01 00:00:00
abstract：:Children and adolescents affected by ulcerative colitis (UC) frequently require colectomy because of refractory or chronic symptoms. The aim of this paper is to present our experience and 10-year follow-up results of 28 patients who underwent endorectal pull-through (ERPT) as surgical treatment for UC, with special re...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-004-1232-5
更新日期：2004-08-01 00:00:00
abstract：PURPOSE:To investigate the safety and efficacy of mucous fistula refeeding (MFR) in low-birth-weight infants. METHODS:Between December 2006 and December 2018, medical records of low-birth-weight infants who underwent small bowel enterostomy formation in the neonatal period and subsequent stoma closure at our instituti...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-019-04533-x
更新日期：2019-10-01 00:00:00
abstract：:For the assessment of germ-cell maturation of the seminiferous tubules, DNA flowcytometry is a rapid and sensitive method. Phosporus 31P magnetic resonance spectroscopy (MRS) is a non-invasive alternative that demonstrates the metabolic status of the testis, reflecting the type and relative proportion of germ cells in...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830100602
更新日期：2001-05-01 00:00:00
abstract：PURPOSE:To compare open repair (OR) with thoracoscopic repair (TR) for congenital diaphragmatic hernia (CDH) in neonates. METHODS:Twenty-four neonatal CDH cases diagnosed prenatally or within 6 h of birth at our institute from 2002 to 2012 with mild pulmonary hypertension managed without inhaled nitric oxide, were stu...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-013-3382-9
更新日期：2013-11-01 00:00:00
abstract：:Diagnostic evaluation and treatment of blunt liver trauma in children have changed essentially over the last decades. In the period between January 1975 and December 2002, a total of 45 children, 18 girls and 27 boys, between the ages of 1 and 16 years (mean 8.19) were treated for liver rupture following blunt abdomin...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-004-1276-6
更新日期：2004-12-01 00:00:00
abstract：:The presacral cystic teratoma in an infant is reported. The cyst consisted solely of central nervous system tissue. This pathologic finding is extremely rare. A review of the literature reveals no previous report of a teratoma arising in this manner. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-002-0831-2
更新日期：2002-12-01 00:00:00
abstract：:Congenital arteriovenous fistulas are a rare cause of neck mass in children, but should be considered in the differential diagnosis of paediatric patients presenting with pulsatile neck masses even when there is no history of trauma. Balloon embolisation is the treatment of choice because of the high risk of surgical ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-011-2918-0
更新日期：2011-12-01 00:00:00
abstract：:Thyroglossal duct cyst (TGDC) disease, one of the most common developmental neck lesion in the pediatric population, often presents as infected neck mass. The authors reviewed their experience in the management of inflamed TGDC cases, in order to suggest the most efficient approach of these patients regarding the idea...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1562-y
更新日期：2005-12-01 00:00:00
abstract：:We analyzed the causes and diagnoses, the treatment, short and long-term outcome of a consecutive series of 70 pediatric polytrauma patients. From 1989 to 1996, 70 children (aged 10 months to 16 years, mean 7.4 years) presented with multiple trauma. A follow-up investigation was performed 4.2 years (mean) after the ac...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-003-0954-0
更新日期：2003-08-01 00:00:00
abstract：:To determine which laser can be used for a vascular lesion, the different working mechanisms of the individual lasers must first be understood. The localization and diameter of the vessels to be treated define whether a certain laser is appropriate for that lesion. For teleangiectasias and port-wine stains the pulsed-...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF00497797
更新日期：1996-06-01 00:00:00
abstract：:The n-3 and n-6 polyunsaturated fatty acids (PUFAs) are essential dietary constituents. They are important as a source of energy, as structural components of cell membranes, and as signalling molecules. They have been demonstrated to be potent modulators of the immune response, and research has endeavoured to optimise...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-005-1385-x
更新日期：2005-05-01 00:00:00
abstract：:Mortality rates in neonatal surgery have dropped markedly, illustrating the enormous progress made. Yet, new questions have arisen. To mention one, health care budgets have tightened. It follows that the effects of medical interventions should be weighted against their costs. As evidence was particularly sparse, we se...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-007-2045-0
更新日期：2008-02-01 00:00:00
abstract：PURPOSE:For 30 years, we have consecutively performed rectal mucosal punch biopsy to diagnose Hirschsprung's disease. The aim of this study was to evaluate the safety of our technique. METHODS:Patients with suspected Hirschsprung's disease who underwent punch biopsy, including our original "K-PUNCH" method using an S-...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-016-4010-2
更新日期：2017-02-01 00:00:00
abstract：:Polyps in gastrointestinal tract are mostly benign and result from hamartomas or lymphoid hyperplasia of submucosa. They usually occur as isolated lesions in children and are referred to as juvenile polyps. Multiple polyps with inherited origin are called polyposis and can be seen as a part of the syndrome. The polyps...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-020-04621-3
更新日期：2020-04-01 00:00:00
abstract：:Endoscopic holmium:yttrium-aluminum-garnet (Ho:YAG) laser incision is a new method applied in pediatric urology recent years. To evaluate its therapeutic efficacy on treating the pediatric patients with urethral strictures and urethral atresias, a retrospective study was performed from June 2001 to July 2005 in a tota...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-006-1692-x
更新日期：2006-06-01 00:00:00
abstract：:A new instrument for suction rectal biopsy in infants suspected of having Hirschsprung's disease is described that can be completely dismantled, physically cleaned, lubricated, and heat-sterilised. These attributes are new and are absolutely critical today. The instrument has been used in 60 patients (ca. 180 biopsies...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF01194812
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:The optimal treatment for pediatric Graves' disease (GD) is controversial. Antithyroid drugs are often used initially, but they are associated with a high failure rate. Therefore alternative therapies have become important. In the present study, we analyze our institution's experience regarding the safety and e...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-012-3095-5
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Pediatric burn injuries are one of the leading causes of preventable morbidity and mortality in Sub-Saharan Africa. Research on the complex system of social, economic and cultural factors contributing to burn injuries in this setting is much needed. METHODS:We conducted a prospective questionnaire-based ana...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3761-5
更新日期：2015-11-01 00:00:00
abstract：PURPOSE:The purpose of this study was to evaluate the applicability of the National Institute for Health and Clinical Excellence (NICE) guidelines for imaging studies in children under the age of three with first urinary tract infection (UTI). METHODS:In our cohort of 112 patients, we gathered data regarding the occur...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-012-3257-5
更新日期：2013-03-01 00:00:00
abstract：:Renal and perinephric abscess in children are uncommon. Three basic pathophysiologic mechanisms are involved, namely, hematogenous spread, ascending infection and contamination by proximity to an infected area. Six pediatric patients diagnosed with renal abscess were treated at our institution from 1990-2000. Five pat...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-002-0888-y
更新日期：2003-04-01 00:00:00
abstract：:Endoscopic management is the accepted form of treatment for posterior urethral valves (PUV). The Nd:YAG laser has been in clinical use for many decades, but has been used only sporadically for ablating PUV. In this study, PUV were diagnosed by micturating cystourethrogram (MCU). In the 9-month period beginning March 1...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050018
更新日期：2000-01-01 00:00:00
abstract：PURPOSE:To report the authors' experience in the management of perforated choledochal cyst with bile peritonitis (PCC) in children. METHODS:Medical records of all children undergoing surgery for PCC at our hospital from May, 2005 to January, 2013 were reviewed. RESULTS:Twenty seven patients were identified, with a me...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3461-6
更新日期：2014-03-01 00:00:00
abstract：INTRODUCTION:Management of oesophageal atresia (OA) and trachea-oesophageal fistula (TOF) in babies of low birth weight is challenging especially when associated with other anomalies. Birth weight of <1500 g has previously formed part of a classification system designed to predict outcome, alongside the cardiac status ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3851-4
更新日期：2016-06-01 00:00:00
