Abstract：
PURPOSE:This study's aim was to assess the use of intravesical injection of botulinum neurotoxin type A (BoNT-A) as a treatment of overactive bladder (OAB) in children. METHODS:A 6-year retrospective study of children who received BoNT-A for OAB was performed. Treatment outcome was classified as complete success (CS), partial success (PS) or treatment failure (TF). RESULTS:Of the 57 patients who received BoNT-A treatment for OAB, 35 were males. CS occurred in 74.2% of males and 54.5% of females. PS was achieved in 20% of males and 18.2% of females. TF occurred in 2.9% of males and 22.7% of females. Anticholinergics had previously been used and had been effective in 58.6% and 83.3% of males and females. Significant side effects to medications were experienced in 12 (41.4%) males and 4 (22.2%) females. Of these, BoNT-A achieved CS in seven (53.3%) males and two (50%) females and PS in three (25%) males and one (25%) female. BoNT-A was successful in seven (58.3%) males and two (66.7%) females where anticholinergics were ineffective. CONCLUSIONS:BoNT-A has a role in a carefully selected subgroup of children with overactive bladder symptoms including those with medication side effects and treatment compliance issues. It may have a role in patients who do not respond to conventional therapy.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
McDowell DT,Noone D,Tareen F,Waldron M,Quinn Fdoi
10.1007/s00383-011-3039-5subject
Has Abstractpub_date
2012-03-01 00:00:00pages
315-20issue
3eissn
0179-0358issn
1437-9813journal_volume
28pub_type
杂志文章abstract：:In severe vaginal malformations, when the distance between the upper vaginal pouch and perineum is too long (6 cm or more), reconstruction of the vagina can be performed by colonic interposition or by long cutaneous flaps obtained by the tissue expansion technique. Two female adolescents were treated using expanded la...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：:Minimally invasive surgery (MIS) for cancer patients has become widely accepted in general surgery, however, it has not completely replaced the standard open operative procedures in pediatric oncology. The aim of this study was to evaluate the host relationship following MIS in a murine model of retroperitoneal neurob...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050271
更新日期：1998-03-01 00:00:00
abstract：PURPOSE:We evaluated the effectiveness of prophylactic mesenteric lymphatic ligation in preventing iatrogenic chylous fistulae in abdominal neuroblastoma surgery. METHOD:All patients who underwent resection of abdominal neuroblastoma between years 2002 and 2013 were included. A change in surgical strategy commenced fr...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3581-z
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:Bone morphogenetic proteins (BMPs) are a group of growth factors that are implicated in intestinal growth, morphogenesis, differentiation, and homeostasis. The role of the BMP signaling cascade in stimulation of cell proliferation after massive small bowel resection is unknown. The purpose of this study was to ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3829-2
更新日期：2016-02-01 00:00:00
abstract：:Around the 30th week of gestation, patients with gastroschisis (GS) develop chronic inflammatory reactions on the serosal surface of the eventrated loops of intestine that lead to severe hyperfibrinogenemia and hypercoagulability, particularly if they are born prematurely. This result was found on comparison of coagul...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF00183729
更新日期：1996-03-01 00:00:00
abstract：:The aim of this study was to compare the safety and benefits of Soave's and Duhamel's pull-through procedures for the management of Hirschsprung's disease (HD). The patients consisted of 33 boys (85%) and six girls (15%), a ratio of 5.5:1. Their ages ranged from 1 day to 8 years. Rectal biopsy was performed to confirm...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-004-1237-0
更新日期：2004-08-01 00:00:00
abstract：:Our purpose was to clarify factors that influence the level of depression of Japanese children with anorectal malformations (ARM). The subjects comprised 66 children with ARM, aged 0-16 years, and their mothers. Patients were divided into three groups (Group 1: aged 0-5 years, Group 2: 6-11 years, and Group 3: 12-16 y...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-2077-5
更新日期：2008-03-01 00:00:00
abstract：:We reviewed our clinical experience of using a computer-powered right angle linear cutter (CPRALC) for Collis-Nissen fundoplication (CNF) in three children with gastroesophageal reflux (GER) or failed Nissen associated with short esophagus. Case 1 was a 13-month-old female with persistent GER after type-C esophageal a...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-009-2455-2
更新日期：2009-11-01 00:00:00
abstract：:Rhabdoid tumour of the kidney is not common. Presentation of such a lethal tumour along with blunt abdominal trauma is even rarer. We report such a case of Rhabdoid tumour of kidney which presented as renal trauma, and discuss the diagnostic difficulties and rapidly fatal outcome. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003839900290
更新日期：2000-01-01 00:00:00
abstract：:The functional outcome and factors influencing improvement after pyeloplasty for ureteropelvic junction (UPJ) obstruction are still debated. This retrospective study was aimed at evaluating the factors associated with functional improvement in symptomatic unilateral hydronephrosis (HDN). Patients (n = 68) who underwen...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830100604
更新日期：2001-09-01 00:00:00
abstract：:Hirschsprung disease is the result of aganglionosis of a variable length of the terminal bowel, which arises from the incomplete colonisation of the embryonic gut by vagal neural crest-derived cells (NCC) that migrate caudally from the pharyngeal gut to the rectum. We have previously shown that a very small group of N...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-002-0868-2
更新日期：2002-10-01 00:00:00
abstract：PURPOSE:Reactive oxygen species (ROS) are thought to contribute to the pathogenesis of necrotizing enterocolitis (NEC). Mitochondria as a major source of intracellular ROS and apoptotic signaling during oxidative stress in NEC have not been investigated. We sought to determine: (1) the effects of oxidative stress on in...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-011-2880-x
更新日期：2011-08-01 00:00:00
abstract：PURPOSE:Gastrostomy tube placement is one of the most commonly performed pediatric surgical procedures and discharge is possible as early as the first postoperative day with early initiation of feeds postoperatively. We examined a national database to determine hospital length of stay (LOS) after elective laparoscopic ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-019-04472-7
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Pediatric burn injuries are one of the leading causes of preventable morbidity and mortality in Sub-Saharan Africa. Research on the complex system of social, economic and cultural factors contributing to burn injuries in this setting is much needed. METHODS:We conducted a prospective questionnaire-based ana...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3761-5
更新日期：2015-11-01 00:00:00
abstract：:To categorize variant persistent müllerian-duct derivatives (MDD) in males and determine their related clinical presentations for further management, five male patients with retained MDDs from abnormal müllerian remnants were studied. They comprised one patient with persistent müllerian-duct syndrome, one with transve...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-002-0718-2
更新日期：2002-09-01 00:00:00
abstract：INTRODUCTION:Applicants in the NRMP for pediatric surgery have little objective data available regarding factors predicting successful matching. We analyzed data from applicants at our institution to attempt to identify parameters correlated with three outcomes: successfully matching, or attaining either a top ten or t...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-011-2912-6
更新日期：2011-11-01 00:00:00
abstract：:Pediatric osteomyelitis commonly occurs in the long bones and has rarely been reported in small bones such as the vertebrae and ribs. Rib osteomyelitis occurs in approximately 1% or less of all cases of hematogenous osteomyelitis, and is usually caused by Staphylococcus aureus. We present a case of acute osteomyelitis...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-006-1725-5
更新日期：2006-10-01 00:00:00
abstract：PURPOSE:Sacrococcygeal teratoma (SCT) is the most common congenital neoplasm in neonates. We wished to assess the long-term functional outcome of children undergoing SCT resection. METHODS:Records of neonates diagnosed with SCT from two surgeons' practices, and operated on between 1970 and 2006, were retrospectively r...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-009-2322-1
更新日期：2009-03-01 00:00:00
abstract：:A review of 100 consecutive cases of congenital diaphragmatic hernia (CDH) treated at our institute focusing on the efficacy of protocolized management (PM) was conducted. Of the 100 cases, 14 who became symptomatic more than 24 h after birth, and seven with fatal anomalies (four cardiac and three chromosomal) were ex...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-006-1759-8
更新日期：2006-11-01 00:00:00
abstract：PURPOSE:Evaluate the management of hydrocephalus in pediatric patients in the Eastern Democratic Republic of Congo by a general surgeon. METHODS:Retrospective review of a single institution in the province of North Kivu. Patient charts and surgical notes were reviewed from 2003 to 2016. RESULTS:116 procedures were pe...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4238-0
更新日期：2018-04-01 00:00:00
abstract：:A case of extrahepatic biliary atresia (EBA) associated with trisomy 18 is presented. A 1-month-old boy was suspected to have Alagille syndrome with obstructive jaundice, a systolic heart murmur, growth retardation, and a small, pointed chin. However, surgery and chromosomal analysis revealed EBA associated with triso...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050536
更新日期：1999-01-01 00:00:00
abstract：:In contrast to adults, calcium carbonate gallstones are relatively common in children. Their pathogenesis is poorly understood. Cystic duct obstruction promotes calcium carbonate formation in bile and increases gallbladder mucin production. We tested the hypothesis that mucin producing epithelial cells would be increa...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-006-1867-5
更新日期：2007-03-01 00:00:00
abstract：PURPOSE:Experience with male cloaca (MC), a single opening in perineum for passage of urine and meconeum is described. METHODS:Cases of MC were ambispectively studied, prospectively from July 2007 to April 2015 and retrospectively for last three decades. RESULTS:Seven cases of MC were identified, between the ages of ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3738-4
更新日期：2015-08-01 00:00:00
abstract：:The management of Hirschsprung's disease (HD) has made dramatic strides over the last 20 years. Research into the embryological development and migration of ganglion cell has enabled a greater understanding of the pathogenesis of the disease. Coupled with new techniques in surgery, such as laparoscopy-assisted pull-th...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-005-1551-1
更新日期：2005-10-01 00:00:00
abstract：AIM OF STUDY:The objective of this study is to determine the diagnostic value of the 24-h delayed film for Hirschsprung's disease (HD). Other features of the barium enema were also examined, in particular the correlation between the radiological transition zone (TZ) and the final pathology. METHODS:All patients with s...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3632-5
更新日期：2015-01-01 00:00:00
abstract：PURPOSE:Historically, the majority of patients with colonic atresia have been managed by ostomy creation at the time of initial operation; conversely, we have tended to treat the atresia with resection and anastomosis. The purpose of this study is to determine the rate of concomitant Hirschsprung's disease and to ident...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-009-2401-3
更新日期：2009-07-01 00:00:00
abstract：AIM:Prepubertal testicular tumors are rare in children. We aim to present clinical and histological features of prepubertal testicular tumors through the analysis of the long-term experiences of a single medical center of China. MATERIALS AND METHODS:A total of 67 children (≤ 14 years) treated for testicular tumor at ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4366-6
更新日期：2018-12-01 00:00:00
abstract：:The confluence of the right and left hepatic ducts at the hepatic hilum frequently shows normal anatomic variations. Choledochal cysts (CC) are also accompanied by similar variations, and devices for free drainage of bile are occasionally required in biliary reconstruction. We present a CC that had an aberrant posteri...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF01371914
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:We aim to evaluate the diagnostic performance and relationship between clinical characteristics, imaging findings, and final diagnosis for the neonatal contrast enema (CE). METHODS:Retrospective 10-year review of all neonatal CEs including imaging findings, clinical information, indication, and final diagnosis...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-020-04701-4
更新日期：2020-09-01 00:00:00
abstract：:There are few publications about urolithiasis of the new born baby and infant (UNI). The UNI represents 20% of the pediatric urolithiasis. The etiologies in this age group are chiefly dominated by the urinary-tract infections and metabolic abnormalities. The purpose of this paper was to investigate the epidemiological...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-007-1889-7
更新日期：2007-04-01 00:00:00
