Abstract:
:Mortality rates in neonatal surgery have dropped markedly, illustrating the enormous progress made. Yet, new questions have arisen. To mention one, health care budgets have tightened. It follows that the effects of medical interventions should be weighted against their costs. As evidence was particularly sparse, we set out to analyse cost-effectiveness of neonatal surgery. The purpose of this article is to summarise our findings and to review recent studies. Moreover, this article explains the relevance of cost-effectiveness analysis and explores how cost-effectiveness interacts with other determinants of health care priority setting. Our research revealed that treatments for two common diagnostic categories in neonatal surgery (congenital anorectal malformations and congenital diaphragmatic hernia) produce good cost-effectiveness. Other groups also published cost-effectiveness studies in the field of neonatal surgery, although their number is still small. Contemporaneously, the economic aspects of health care have captured the interest of policy makers. Importantly, this is not to say that there are no other factors playing a role in priority setting, foremost among which are ethical questions and arguments of equity. This article concludes that, according to present evidence, neonatal surgery yields good value for money and contributes to equity in health.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Poley MJ,Brouwer WB,Busschbach JJ,Hazebroek FW,Tibboel D,Rutten FF,Molenaar JCdoi
10.1007/s00383-007-2045-0subject
Has Abstractpub_date
2008-02-01 00:00:00pages
119-27issue
2eissn
0179-0358issn
1437-9813journal_volume
24pub_type
杂志文章,评审abstract:PURPOSE:Primary spontaneous pneumothorax (PSP) is managed in accordance with the adult British Thoracic Society (BTS) guidelines due to lack of paediatric evidence and consensus. We aim to highlight the differences and provide a best practice surgical management strategy for PSP based on experience of two major paediat...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3787-8
更新日期:2015-12-01 00:00:00
abstract::An experimental study was conducted to determine the end-results of two different defects on the anterior abdominal wall: an abdominal wall defect (AWD) versus an umbilical cord defect (UCD) using chick embryos. The AWD was created by leaving an intact skin bridge between the defect and the umbilical cord in group 1; ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF01371904
更新日期:1997-01-01 00:00:00
abstract:PURPOSE:Bone morphogenetic proteins (BMPs) are a group of growth factors that are implicated in intestinal growth, morphogenesis, differentiation, and homeostasis. The role of the BMP signaling cascade in stimulation of cell proliferation after massive small bowel resection is unknown. The purpose of this study was to ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3829-2
更新日期:2016-02-01 00:00:00
abstract::Pyloric atresia (PA) is an uncommon anomaly that may be associated with many other congenital anomalies, the commonest of which is junctional epidermolysis bullosa (JEB). Most of the cases of PA associated with JEB (Herlitz syndrome) reported have been fatal. A case of PA associated with JEB, malrotation, and a high a...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050572
更新日期:1999-01-01 00:00:00
abstract::Hirschsprung's disease is characterized by the absence of ganglion cells in the distal bowel and extends proximally for varying distances. In recent years, the purinergic P2Y receptors have begun to receive much attention as they have been recognised as major ATP receptors in many regions of the body, including the in...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-2044-1
更新日期:2008-01-01 00:00:00
abstract::The aim of this study is to evaluate the safety and efficacy of the redo transanal endorectal pull-through (TEPT) for patients with persistent symptoms after pull-through for Hirschsprung's disease (HD). Seven children were included in the study, their ages ranged from 2.5 to 6 years (four males and three females). Th...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1837-y
更新日期:2007-02-01 00:00:00
abstract::The purpose of this study is to evaluate the efficacy of intraoperative radiation therapy (IORT) and the problem of securing the IORT field in advanced pediatric neuroblastoma. Between 1996 and 2005, 12 children received IORT for advanced pediatric neuroblastoma patients. Electron beam energies ranged from 10 to 12 Me...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-2065-9
更新日期:2007-12-01 00:00:00
abstract:PURPOSE:Eosinophilic gastrointestinal disorders are rare in children and present with a broad spectrum of non-specific symptoms. To date, no guidelines for diagnosis, therapy and follow-up are validated. Aim of our study is to focus on eosinophilic colitis (EC), to determine a possible correlation between associated di...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-020-04832-8
更新日期:2021-01-07 00:00:00
abstract::Cystic teratoma of the pancreas is an extremely rare entity: only 11 cases have been described so far in the world literature. We report the 12th case, in a 4-month-old girl. ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF00183759
更新日期:1996-03-01 00:00:00
abstract:PURPOSE:This study's aim was to assess the use of intravesical injection of botulinum neurotoxin type A (BoNT-A) as a treatment of overactive bladder (OAB) in children. METHODS:A 6-year retrospective study of children who received BoNT-A for OAB was performed. Treatment outcome was classified as complete success (CS),...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-011-3039-5
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:Although the precise pathogenesis of ventral body wall (VBW) defects is not clearly understood, it has recently postulated that disruption of somite development during early embryogenesis may cause failure of proper VBW formation. The administration of cadmium (Cd) after 60 h of incubation induces omphalocele s...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-011-2994-1
更新日期:2012-02-01 00:00:00
abstract::Retrocaval ureter is a relatively rare anomaly that usually manifests in the third or fourth decades. Symptoms are due to ureteric obstruction, either extrinsic by the abnormal inferior vena cava (IVC), or intrinsic ureteric hypoplasia. Surgery is needed for symptomatic cases and involves transection and relocation of...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-003-1038-x
更新日期:2004-02-01 00:00:00
abstract::Our purpose was to clarify factors that influence the level of depression of Japanese children with anorectal malformations (ARM). The subjects comprised 66 children with ARM, aged 0-16 years, and their mothers. Patients were divided into three groups (Group 1: aged 0-5 years, Group 2: 6-11 years, and Group 3: 12-16 y...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-2077-5
更新日期:2008-03-01 00:00:00
abstract:INTRODUCTION:Bladder Bowel Dysfunction (BBD) has been described in patients with Down's Syndrome (DS). Our aim was to report the incidence, demographics, presentation, complications and management of the bladder in DS patients with BBD. METHODS:A systematic review was performed using PRISMA guidelines and search terms...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-020-04682-4
更新日期:2020-07-01 00:00:00
abstract::A simple, quick, painless, and versatile dressing that fulfills most of the criteria of an ideal hypospadias dressing is described. ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1206-7
更新日期:2004-05-01 00:00:00
abstract::When presentation is delayed, intussusceptions may be difficult to reduce using standard enema regimens. Our endeavour to minimize the need for surgery in an environment where failed reductions are common has led to the development of an aggressive, non-operative method of reducing intussusceptions. One hundred and si...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-003-1099-x
更新日期:2004-03-01 00:00:00
abstract:PURPOSE:Perianal fistulous disease is present in 10-15% of children with Crohn's disease (CD) and is frequently complex and refractory to treatment, with one-third of patients having recurrent lesions. We conducted a systematic review of the literature to examine the best surgical strategy or strategies for pediatric c...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-017-4067-6
更新日期:2017-05-01 00:00:00
abstract::Obstruction of the ureterovesical junction is an uncommon but well-recognized complication of ureteral reimplantation that traditionally has been treated by surgical correction [1, 5-9]. We report our experience with antegrade balloon dilation (ABD) of these strictures in two children. Obstruction was confirmed by diu...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF00626067
更新日期:1996-10-01 00:00:00
abstract::Repair of recurrent tracheoesophageal fistula (TEF) after repair of congenital esophageal atresia continues to be a difficult problem. The most common re-operation for a recurrent TEF involves repair via a right thoracotomy and use of a flap as interposed tissue between the closure sites. Although several materials ha...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-012-3255-7
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:Recognition of physical child abuse is imperative for ensuring children's safety. Screening tools (ST) may increase identification of physical abuse; however, the extent of their use is unknown. This study assessed use of STs for physical abuse in children's hospitals and determined attitudes regarding STs. ME...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-016-3916-z
更新日期:2016-08-01 00:00:00
abstract::Our case report details the clinical course and management of a neonate with acute life-threatening respiratory distress presenting soon after birth. She needed intubation and ventilation. A pericardial cyst was diagnosed after a CT scan and 2D echo investigation. As a temporizing procedure the fluid was tapped and th...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-003-0970-0
更新日期:2003-11-01 00:00:00
abstract::Gastroschisis is traditionally managed by primary closure (PC) or delayed closure after surgical silo placement. Bedside insertion of preformed silos (PFS) and delayed closure has become more widespread, although its benefits remain unclear. To identify differences in outcome of infants managed with PFS compared with ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-2004-9
更新日期:2007-11-01 00:00:00
abstract::To categorize variant persistent müllerian-duct derivatives (MDD) in males and determine their related clinical presentations for further management, five male patients with retained MDDs from abnormal müllerian remnants were studied. They comprised one patient with persistent müllerian-duct syndrome, one with transve...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-002-0718-2
更新日期:2002-09-01 00:00:00
abstract::With widespread use of antenatal ultrasound, an increasing number of urinary-tract lesions are being detected, and the clinician is called upon to make management decisions. Parenchymal lesions of the kidney pose a special challenge because of the associated risk of the occurrence of malignancy. A case of an antenatal...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-002-0833-0
更新日期:2003-04-01 00:00:00
abstract::A newborn case with cardiac rhabdomyoma is presented to discuss the differential diagnosis of mediastinal tumors around the heart in children. The diagnosis of rhabdomyoma can be suggested by modern visualization methods such as computerized tomography, magnetic resonance imaging and echocardiography. However, surgery...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-1875-0
更新日期:2007-08-01 00:00:00
abstract::An unrecognised right aortic arch (RAA) found at thoracotomy may complicate the repair of oesophageal atresia (OA) and tracheo-oesophageal fistula (TOF). This paper analyses the patient characteristics, peri-operative management, and outcome of 16 infants with a RAA, and proposes management guidelines. Between 1948 an...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050505
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:Experience with male cloaca (MC), a single opening in perineum for passage of urine and meconeum is described. METHODS:Cases of MC were ambispectively studied, prospectively from July 2007 to April 2015 and retrospectively for last three decades. RESULTS:Seven cases of MC were identified, between the ages of ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3738-4
更新日期:2015-08-01 00:00:00
abstract::A congenital diaphragmatic hernia (CDH) model was induced in pregnant rats following administration of 100 mg nitrofen. The fetuses were stored and fixed in Bouin's solution for 24 h after caesarean section at term. After fixation, the lungs were dissected out. Immunostaining of the CDH lungs and controls with rabbit ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF00180080
更新日期:1996-08-01 00:00:00
abstract::Esophageal hiatal hernias (EHH) are probably caused by congenital, traumatic, or iatrogenic factors, although the etiology remains unknown. EHHs may develop after abdominal wall closure for omphalocele or gastroschisis due to the increased intra-abdominal pressure, however, there have been few reports in the literatur...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050352
更新日期:1998-07-01 00:00:00
abstract::Surgical extirpation is the treatment of choice for symptomatic mullerian duct remnants (prostatic utricle, PU), and several surgical approaches have been described for the treatment of this pathology. A group of 11 patients with symptomatic PU were observed and treated. Associated anomalies included proximal or penos...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:
更新日期:1997-03-21 00:00:00