Abstract：
PURPOSE:For 30 years, we have consecutively performed rectal mucosal punch biopsy to diagnose Hirschsprung's disease. The aim of this study was to evaluate the safety of our technique. METHODS:Patients with suspected Hirschsprung's disease who underwent punch biopsy, including our original "K-PUNCH" method using an S-moid forceps and non-specific blood-collecting tube at our department and branch hospital between April 1986 and March 2016 were included in the present study. Our punch biopsy technique is characterized by excellent visibility and a direct grasping sensation. The backgrounds and complications of the patients were retrospectively investigated. RESULTS:During this period, 954 patients (median age 4 months; range 1 day-73 years) underwent punch biopsy. Although there were no cases of severe complications (i.e., rectal perforation, infection or full-thickness biopsy), one (0.1%) of the 954 cases in the early period showed liver dysfunction and required transfusion due to bleeding. In addition, inappropriate specimens were obtained in 37 patients (3.9%). CONCLUSION:Punch biopsy including the "K-PUNCH" method is considered safe and feasible and is associated with a low rate of complications and inappropriate specimen harvesting among patients of all ages. Comorbidities, including the potential for hemorrhage, should always be considered.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Yoshimaru K,Kinoshita Y,Yanagi Y,Obata S,Jimbo T,Iwanaka T,Takahashi Y,Esumi G,Miyata JA,Matsuura T,Izaki T,Taguchi Tdoi
10.1007/s00383-016-4010-2subject
Has Abstractpub_date
2017-02-01 00:00:00pages
173-179issue
2eissn
0179-0358issn
1437-9813pii
10.1007/s00383-016-4010-2journal_volume
33pub_type
杂志文章abstract：PURPOSE:Lgr5+ intestinal epithelial stem cells (ISCs) crucial for intestinal epithelial regeneration are impaired during necrotizing enterocolitis. This study aims to investigate the influence of different stressors on intestinal epithelial injury and regeneration in vitro. METHODS:Intestinal epithelial cells (IEC-18)...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-017-4183-3
更新日期：2018-02-01 00:00:00
abstract：:The morphogenesis of the external genitalia of human fetuses (16-250 mm crown-rump [CR] length, 6-26 weeks of gestation) obtained after medical termination of pregnancy were studied. Differential development (male/female) started after 50 mm CR length (9 weeks). At that time the external genitalia consisted of a cylin...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF01076950
更新日期：1997-07-01 00:00:00
abstract：:The management of a critical airway in infants and toddlers with congenital tracheal stenosis (CTS) continues to be an enormous challenge to the surgeon. Until recently, this condition often proved fatal. Improvements in surgical techniques, anesthetic management, and postoperative critical care have resulted in succe...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s003830050028
更新日期：2000-01-01 00:00:00
abstract：:The introduction of posterior sagittal anorectoplasty (PSARP) by deVries and Peña in the early 80s has impacted to the treatment of patients with anorectal malformations (ARM). It gained great recognition worldwide in a very short time, and since then, surgeons dealing with the treatment of this complex malformation c...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-020-04629-9
更新日期：2020-04-01 00:00:00
abstract：PURPOSE:Partial hepatectomy (PH) can be an inevitable surgical therapy in some conditions, such as hepatic malignancies, trauma or partial liver transplantation. Its capacity for regeneration distinguishes the liver from other essential organs. Regeneration is a complex process involving growth factors, cytokines, tran...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-009-2529-1
更新日期：2010-02-01 00:00:00
abstract：PURPOSE:The goal of this study was to determine the degree of consensus in the management of spinal cord tethering (TC) in patients with anorectal malformation (ARM) in a large cohort of European pediatric centers. METHODS:A survey was sent to pediatric surgeons (one per center) members of the ARM-Net Consortium. RES...
journal_title：Pediatric surgery international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00383-017-4105-4
更新日期：2017-08-01 00:00:00
abstract：:An infant born in the 34th week of gestation weighing 5,355 g with a massive sacrococcygeal (SC) tumor was delivered by elective cesarean section. An ultrasonographic examination showed solid and cystic components in the tumor. Resection was successfully undertaken with insertion of a Nélaton catheter into the rectum ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830000451
更新日期：2001-03-01 00:00:00
abstract：:Pediatric vascular injuries are increasing in frequency and represent a challenging problem in pediatric surgical practice. Increased survival of low birth weight infants and advances in invasive diagnostic procedures have resulted in a dramatic increase in the number of these injuries. Formation of pseudoaneurysm of ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-004-1238-z
更新日期：2004-08-01 00:00:00
abstract：:It is unknown whether noncomplicated acute appendicitis cause bacterial translocation. In this study, we aimed to test development of the bacterial translocation in the patients who were operated for acute appendicitis. In this prospective study, 10 control patients who underwent elective operations because of other r...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-1899-5
更新日期：2007-06-01 00:00:00
abstract：:Intussusception is the commonest surgical complication of Henoch-Sch onlein purpura (HSP), occurring in 1.3%-13.6% of affected children. Colo-colic intussusception is a rare occurrence in HSP, with only three other reported cases. Intussusception in HSP almost always originates in the ileum (90%) or jejunum (7%), and ...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s003830050478
更新日期：1998-12-01 00:00:00
abstract：:Recent studies of testicular descent suggest not only that the gubernaculum does not initially attach to the scrotum, but also that it must migrate from the groin. Two findings suggest that the gubernaculum may behave like an embryonic limb bud during this phase. First, the active growth centre is at the distal tip of...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-007-1907-9
更新日期：2007-07-01 00:00:00
abstract：:Internal anal sphincter achalasia (IASA) is a condition with a clinical presentation similar to Hirschsprung's disease, but with the presence of ganglion cells on rectal biopsy. The diagnosis of IASA is made on anorectal manometry, which demonstrates the absence of a rectosphincteric reflux on rectal balloon inflation...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050552
更新日期：1999-01-01 00:00:00
abstract：:In children with severe chronic constipation, abnormal distribution of substance P (SP) and vasoactive intestinal peptide (VIP), which represent excitatory and inhibitory nerves, respectively, has been reported. The normal distribution of these neuropeptides, however, is not well known. The aim of this study was to de...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050438
更新日期：1998-11-01 00:00:00
abstract：:Fetal lambs with diaphragmatic herniae (CDH) created surgically at 73 days' gestation were subjected to three different forms of intrauterine correction: silastic patch correction of the diaphragmatic defect plus an abdominal patch at 101 days gestation; an intrathoracic "silo" at 101 days; and a tracheal "plug" obstr...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF00626057
更新日期：1996-10-01 00:00:00
abstract：PURPOSE:We previously showed that meticulous probing and resection of the intrahepatic bile duct stenosis (IHBDS)-causing membrane or septum was effective in preventing hepatolithiasis after choledochal cyst excisions in open surgeries. Then, we introduced this maneuver into laparoscopic choledochal cyst excisions in 2...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4320-7
更新日期：2018-10-01 00:00:00
abstract：:Nitrofen induces in rats diaphragmatic hernia (CDH) with heart and lung hypoplasia by a mechanism involving oxidation. The aim of this study was to examine if prenatal administration of the anti-oxidant agent vitamin E (VitE) prevents to some extent heart and lung hypoplasia. Pregnant rats received on E9.5 either 100 ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-003-1005-6
更新日期：2003-07-01 00:00:00
abstract：:An infant developed massive lower gastrointestinal haemorrhage secondary to necrotising enterocolitis after cardiac surgery. The haemorrhage was only controlled following a colectomy. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050613
更新日期：1999-07-01 00:00:00
abstract：PURPOSE:In 2006, The Japanese Society of Pediatric Endoscopic Surgeons devised a plan to develop a pediatric endoscopic surgical skill qualification (ESSQ) system. This system is controlled by The Japan Society for Endoscopic Surgery. The standard requirement for skills qualification is the ability of each applicant to...
journal_title：Pediatric surgery international
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00383-011-2871-y
更新日期：2011-07-01 00:00:00
abstract：:This report describes three children, age range 7 weeks to 5 months, who presented with obstructive jaundice secondary to gallstones. Previous Escherichia coli septicaemia and frusemide therapy were predisposing risk factors in two of the patients. All three were successfully treated with cholecystectomy and explorati...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：PURPOSE:The surgical treatment of children with H-fistula is one of the understudied problems of the present day, especially regarding its high rates of complications. The surgical technique of bringing down the anterior wall of rectum in clinical practice allows us in reducing the rate of H-fistula recurrences. The re...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-008-2234-5
更新日期：2008-11-01 00:00:00
abstract：:Endoscopic management is the accepted form of treatment for posterior urethral valves (PUV). The Nd:YAG laser has been in clinical use for many decades, but has been used only sporadically for ablating PUV. In this study, PUV were diagnosed by micturating cystourethrogram (MCU). In the 9-month period beginning March 1...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050018
更新日期：2000-01-01 00:00:00
abstract：:Intestinal ischemia-reperfusion (IIR) is a complex phenomenon causing local and remote tissue destruction, and even multiple-organ failure. To examine the hypothesis that IIR affects renal function, 21-day-old male Sprague-Dawley rats underwent 45 min superior mesenteric artery occlusion and control rats were subjecte...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-002-0834-z
更新日期：2002-09-01 00:00:00
abstract：:Gastroschisis closure is performed either primarily or after staged reduction of the prolapsed bowel. A technique for surgical closure of the abdominal wall defect is described which allows for an almost scarless appearance of the abdominal surface with preservation of a midline umbilicus. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-008-2215-8
更新日期：2008-09-01 00:00:00
abstract：PURPOSE:This study aimed to evaluate the mid-term outcomes of single-stage modified anterior sagittal anorectoplasty (ASARP) for anorectal malformation with vestibular fistula. METHOD:Twenty-six patients with congenital imperforate anus and vestibular fistula underwent single-stage modified sphincter-saving ASARP betw...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3749-1
更新日期：2015-09-01 00:00:00
abstract：AIM:Prepubertal testicular tumors are rare in children. We aim to present clinical and histological features of prepubertal testicular tumors through the analysis of the long-term experiences of a single medical center of China. MATERIALS AND METHODS:A total of 67 children (≤ 14 years) treated for testicular tumor at ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4366-6
更新日期：2018-12-01 00:00:00
abstract：:Necrotizing fasciitis (NF) is a potentially life-threatening infection of soft tissues. It is characterized by rapid spread of inflammation and infection with widespread necrosis of fascia, subcutaneous tissues, and overlying skin. NF is usually reported in adults with preexisting medical conditions or compromised imm...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1481-y
更新日期：2005-08-01 00:00:00
abstract：PURPOSE:Intestinal perforation (IP) is a fatal complication in extremely low birth weight infants (ELBWI). We started administrating enteral miconazole (MCZ) to ELBWI in 2002. Since then, the incidence of IP has significantly decreased. The aim of this study was to elucidate the prophylactic effect of MCZ for the treat...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-016-3946-6
更新日期：2016-10-01 00:00:00
abstract：:The issues of sexual function and fertility are becoming relevant in patients with posterior urethral valves (PUV), as more of them reach adulthood. To evaluate the semen of post-pubertal patients with PUV as a determinant of future fertility, all such patients (age >16 years) attending the follow-up urology clinic of...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830100679
更新日期：2002-03-01 00:00:00
abstract：:Various options are available for the surgical treatment of meconium ileus (MI). This paper examines the use of resection and primary anastomosis as the favoured option for the treatment of complicated meconium ileus. This was a retrospective study. All patients (13 children) with MI treated with primary resection and...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-2020-9
更新日期：2007-11-01 00:00:00
abstract：INTRODUCTION:Though the lifetime risk of colorectal carcinoma (CRC) in general population is 5-6 %, it is uncommon in pediatric age group. Here, we are reporting our experience of CRC in the first decade of life. METHODS:From January 2010 to December 2013, seven patients with histopathologically confirmed colorectal c...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3537-3
更新日期：2014-08-01 00:00:00
