Abstract:
:Early diagnosis, followed by early initiation and optimal adjustments of aggressive therapies, are acknowledged as essential to optimize long-term clinical and radiological outcome in rheumatoid arthritis (RA). This requires sensitive methods for detection and monitoring of the primary feature of RA--the synovitis. In comparison with conventional methods, magnetic resonance imaging (MRI) offers assessment of the rheumatoid synovium with improved sensitivity to early pathology and to change. Various aspects such as volume, vascularity, and edema can be assessed by different metrological approaches. MRI findings are of prognostic value to the long-term radiological outcome. This article reviews current knowledge on MRI for assessment of the synovium in RA, focusing on the validity of MRI measures of synovitis. Future perspectives and suggested research priorities are described. The rationale is provided for MRI becoming the new gold standard for assessment of RA joints and for MRI assessments of synovitis being reliable and valid measures of rheumatoid disease activity.
journal_name
Semin Musculoskelet Radioljournal_title
Seminars in musculoskeletal radiologyauthors
Ostergaard M,Ejbjerg Bdoi
10.1055/s-2004-861576subject
Has Abstractpub_date
2004-12-01 00:00:00pages
287-99issue
4eissn
1089-7860issn
1098-898Xjournal_volume
8pub_type
杂志文章,评审abstract::Benign bone cysts (aneurysmal and unicameral) often require treatment to prevent pathological fractures. Percutaneous injections are less invasive than surgery. We describe the different percutaneous treatments available: local injection of steroids, calcitonin, or bone marrow in unicameral bone cysts, and Ethibloc(R)...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-2008-1080152
更新日期:1997-01-01 00:00:00
abstract::Disability is a condition or function that is judged to be significantly impairing relative to the usual standard of an individual or group. The spectrum of musculoskeletal disabilities in children is immense and varied. Musculoskeletal disabilities are congenital or acquired; they affect a child partially or generall...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0034-1389269
更新日期:2014-11-01 00:00:00
abstract::The accuracy, pitfalls, and limitations of magnetic resonance (MR) imaging for diagnosing a tear in the nonoperated knee are well known. However, the diagnosis of a recurrent tear can be more difficult in the postoperative meniscus. Resection or meniscal repair results in postoperative changes that can mimic a recurre...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2005-872337
更新日期:2005-06-01 00:00:00
abstract::For the evaluation of soft tissue masses, sonography (US) has proved to be very accurate in confirming the presence or absence of a lesion, with a very high negative predictive value. Many soft tissue masses result from trauma, inflammation, infection, or cystic changes and are not true neoplasms. In the proper clinic...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-2008-1080056
更新日期:1999-01-01 00:00:00
abstract::Awareness of risk factors associated with impending fracture and its radiologic appearance allows early diagnosis, supports prophylactic surgical treatment, and prevents the multiple complications of a pathologic fracture. Because the femur is the most common long bone affected by metastatic bone lesions, we address t...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0038-1675804
更新日期:2019-02-01 00:00:00
abstract::A potential treatment for chronic tendinosis or tendinopathy is percutaneous ultrasound-guided tendon fenestration, also termed dry needling or tenotomy. This procedure involves gently passing a needle through the abnormal tendon multiple times to change a chronic degenerative process into an acute condition that is m...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0033-1333942
更新日期:2013-02-01 00:00:00
abstract::This article reviews the basics of image-guided intervention of musculoskeletal neoplasms. Image-guided procedures are playing an ever-increasing role in the diagnosis, staging, and treatment of musculoskeletal tumors. The successful handling of these lesions necessitates a multidisciplinary approach, with the radiolo...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0033-1343096
更新日期:2013-04-01 00:00:00
abstract::Biostatistics is an essential component in most original research studies in imaging. In this article we discuss five key statistical concepts for study design and analyses in modern imaging research: statistical hypothesis testing, particularly focusing on noninferiority studies; imaging outcomes especially when ther...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0036-1597252
更新日期:2017-02-01 00:00:00
abstract::In patients with hemophilia, hemarthrosis often occurs in one or several joints and may progress to a destructive, disabling arthropathy. Treatment includes continuous or on-demand clotting factor replacement and radionuclide or open synovectomy. The radiographic findings of hemophilic arthropathy depend on the stage ...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2003-41346
更新日期:2003-06-01 00:00:00
abstract::This paper has been written to stimulate the radiologist to consider the various aspects of spinal steroid injections as therapeutic procedures. Special emphasis is placed on needle guidance, asepsis, and possible problems involved. It constitutes a highly practical and variously illustrated and informative guide for ...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-2008-1080142
更新日期:1997-01-01 00:00:00
abstract::The triangular fibrocartilage complex (TFCC) is a crucial structure for both maintaining the stability of the distal radioulnar joint (DRUJ) and acting as a cushion for axial loading of the ulnocarpal joint. Injury to the TFCC can lead to early degeneration of the DRUJ and ulnocarpal joint, with resultant chronic wris...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0039-1688715
更新日期:2019-08-01 00:00:00
abstract::Fractures and dislocations of the elbow usually occur secondary to indirect trauma. In the adult, fractures of the distal humerus almost always involve the condyles. Fractures of the radial head and neck may be subtle, and the appearance of secondary signs, such as the elevated fat pads from an elbow joint effusion, m...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2000-13011
更新日期:2000-01-01 00:00:00
abstract::Muscle edema is commonly encountered in patients following extremity trauma. This article presents an overview of differential considerations in patients presenting with muscle edema, and while focusing on trauma outlines causes on the basis of mechanism, vasogenic, congestive, traumatic, and tumorigenic edema. ...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-971997
更新日期:2006-12-01 00:00:00
abstract::The evaluation of muscle diseases has traditionally integrated clinical with biochemical findings, occasionally resorting to muscle biopsy. This article reviews the role and imaging appearances of muscle diseases at MRI, specifically emphasising the role of WBMRI in global assessment of muscle abnormality, and in part...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0030-1248704
更新日期:2010-03-01 00:00:00
abstract::Healthy cartilage is essential for normal joint function, and osteoarthritis is the end result of cartilage injury. Hip osteoarthritis was once believed to be a disease of old age; however, younger individuals with femoroacetabular impingement have been found to have premature cartilage injury due to potentially treat...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0033-1348092
更新日期:2013-07-01 00:00:00
abstract::31Phosphorus (31P) magnetic resonance spectroscopy (MRS) is well suited for gathering data on skeletal muscle energetics in vivo. The technique has evolved to the point where it has become an important tool in the study of the pathophysiology both of rare primary disorders of muscle such as the mitochondrial myopathie...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2000-13172
更新日期:2000-01-01 00:00:00
abstract::This article provides a brief review of the normal osseous, ligamentous, muscular, and neurovascular imaging anatomy of the elbow. Special attention is paid to the normal structures that may simulate pathology, as well as anatomical variants that may lead to pathology. This review will help clarify distinctions betwee...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0030-1263254
更新日期:2010-09-01 00:00:00
abstract::There is a broad spectrum of benign soft tissue tumors in children, including, among others, vascular, fibroblastic/myofibroblastic, and adipocytic lesions as well as pseudotumors. The diagnosis of superficial soft tissue tumors is in many instances made clinically, whereas those with more equivocal presentation and t...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0029-1237689
更新日期:2009-09-01 00:00:00
abstract::Examination of the brachial plexus with ultrasound is efficient because it allows many parts of the brachial plexus as well as the surrounding soft tissues to be assessed with high spatial resolution. The key to performing good ultrasound of the brachial plexus is being familiar with the anatomy and the common variant...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0038-1645862
更新日期:2018-07-01 00:00:00
abstract::MRI of the peripheral nerves continues to grow technologically and in clinical use. This article reviews the technological aspects and basic interpretation of high-resolution MR imaging of the upper extremity nerves. These techniques work with 1.5-, or preferably 3-T, scanners regardless of vendors. The article also i...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0035-1545078
更新日期:2015-04-01 00:00:00
abstract::The treatment of articular cartilage injuries remains a challenge because cartilage has a limited capacity for spontaneous repair. Over the past decade, a number of surgical interventions have been developed to produce a durable repair. This article reviews the available treatment options, including their indications,...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2001-19044
更新日期:2001-12-01 00:00:00
abstract::The acromioclavicular joint is an important component of the shoulder girdle experiencing significant loading during normal activities of daily living. The joint is frequently subjected to trauma and as a synovial articulation can become involved in rheumatoid arthritis and the seronegative arthropathies. ...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-0035-1549323
更新日期:2015-07-01 00:00:00
abstract::Ligamentous injuries of the elbow are common in sports. The diagnosis is usually based on a combination of the assessment of the mechanism of injury during the sporting activity and physical examination. Imaging with radiographs and MR imaging has an important diagnostic role, particularly when the clinical presentati...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0033-1360666
更新日期:2013-11-01 00:00:00
abstract::Ultrasound is a nonionizing, low-cost, portable imaging technique for the evaluation of tendons, muscles, joints, soft tissue masses, and cysts, especially in patients unable to tolerate computed tomography or magnetic resonance imaging. These advantages make ultrasound an ideal modality for guiding musculoskeletal in...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-1001883
更新日期:2007-06-01 00:00:00
abstract::Over the last 2 decades, the definition of pathomechanical concepts that link osseous deformities to chondrolabral damage and expose young and active patients to the risk of early osteoarthritis has led to a tremendous increase in the number of joint-preserving surgeries performed. The rise in arthroscopic procedures ...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0039-1678729
更新日期:2019-06-01 00:00:00
abstract::Fractures are common in children with some requiring surgical reduction and fixation to maintain anatomical alignment. Although various surgical techniques and principles are shared between children and adults, certain unique considerations in children can influence the surgical approach and device selection. In parti...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0037-1609013
更新日期:2018-02-01 00:00:00
abstract::Radiographic interpretation of pediatric elbow trauma presents a daunting task for both the radiologist and treating orthopaedic surgeon. Proper radiographic diagnosis and appropriate intervention requires a thorough understanding and appreciation of developmental anatomy. As the pediatric elbow matures, it transition...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-2007-984412
更新日期:2007-03-01 00:00:00
abstract::Painful total knee arthroplasty (TKA) represents a diagnostic challenge for the clinician and radiologist, as there is a wide variety of potential etiologies, with a broad range of clinical presentations, and the abnormalities on imaging studies are often subtle, absent, or nonspecific. Imaging findings of normal TKA ...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2006-934216
更新日期:2006-03-01 00:00:00
abstract::Rheumatoid arthritis (RA) has historically been a disabling and life-threatening disease. Features include joint pain, stiffness and swelling, joint damage, fatigue, loss of function, and loss of employment. Recent advances in treatment, particularly the use of conventional disease-modifying therapies earlier and in c...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-0032-1329878
更新日期:2012-11-01 00:00:00
abstract::High field magnetic resonance imaging at 3.0 T is rapidly gaining clinical acceptance as the preferred platform for magnetic resonance (MR) imaging. This is spurred in part because advances in the manufacture of magnet technology have brought the cost of 3.0-T magnets into the range of previous 1.5-T machines, as well...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0028-1083103
更新日期:2008-09-01 00:00:00