Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS).

abstract：AIMS:To investigate the efficacy and outcome of emergency percutaneous coronary interventions (PCI) in patients with stent thrombosis. METHODS AND RESULTS:Between 1995 and 2003, 6058 patients underwent bare-metal stent implantation, of which 95 (1.6%) patients suffered from stent thrombosis. The timing of stent thromb...

journal_title：European heart journal

authors： Wenaweser P,Rey C,Eberli FR,Togni M,Tüller D,Locher S,Remondino A,Seiler C,Hess OM,Meier B,Windecker S

更新日期：2005-06-01 00:00:00

abstract：:The natriuretic peptides are important tools to establish diagnosis and prognosis in heart failure (HF). With application of therapies for HF, changes in both B-type natriuretic peptide (BNP) and its amino terminal cleavage fragment (NT-proBNP) parallel the benefits of the HF therapy applied. This dynamic nature of BN...

journal_title：European heart journal

authors： Troughton R,Michael Felker G,Januzzi JL Jr

更新日期：2014-01-01 00:00:00

abstract：:The effects of flosequinan and enalapril on exercise capacity (bicycle exercise duration), quality-of-life symptomatology (visual analogue scales) and New York Heart Association (NYHA) grading, were compared in 61 patients with chronic heart failure (NYHA, grade III). Bicycle exercise duration improved similarly with ...

journal_title：European heart journal

authors： Silke B,Tennet H,Fischer-Hansen J,Keller N,Heikkila J,Salminen K

更新日期：1992-08-01 00:00:00

abstract：AIMS:Sudden unexplained death syndrome occurs in previously healthy South-east Asian young adults without any structural cause of death. The common electrocardiographic (ECG) change in sudden unexplained death syndrome survivors is right bundle branch block and ST elevations in leads V(1) to V(3), which are similar to ...

journal_title：European heart journal

authors： Sangwatanaroj S,Prechawat S,Sunsaneewitayakul B,Sitthisook S,Tosukhowong P,Tungsanga K

更新日期：2001-12-01 00:00:00

abstract：:The long-term efficacy of transdermal nitrate therapy, in particular the ability of a single patch to provide 24 h prophylaxis against angina, has been questioned. Two mechanisms have been suggested for this loss of effect: the development of pharmacological tolerance, and premature patch exhaustion. This study was de...

journal_title：European heart journal

authors： James MA,Papouchado M,Jones JV

更新日期：1991-12-01 00:00:00

abstract：:Food constituents can either promote cardiovascular health or serve in its demise. In view of the lack of more effective pharmacological interventions in cardiovascular disease (CVDs), attention has focused on the potential protective effects of diet. Food components and their metabolites are emerging as major regulat...

journal_title：European heart journal

authors： Lionetti V,Tuana BS,Casieri V,Parikh M,Pierce GN

更新日期：2019-02-14 00:00:00

abstract：AIMS:The vast majority of acute heart failure (AHF) trials to date have targeted dyspnoea. However, they enrolled patients relatively late and did not standardize their methods of dyspnoea measurement. URGENT Dyspnoea was designed to determine changes in dyspnoea in response to initial, standard therapy in patients pre...

journal_title：European heart journal

authors： Mebazaa A,Pang PS,Tavares M,Collins SP,Storrow AB,Laribi S,Andre S,Mark Courtney D,Hasa J,Spinar J,Masip J,Frank Peacock W,Sliwa K,Gayat E,Filippatos G,Cleland JG,Gheorghiade M

更新日期：2010-04-01 00:00:00

abstract：:Chronic total occlusions (CTOs) are a subset of lesions that present a considerable burden to cardiovascular patients. There exists a strong clinical desire to improve non-surgical options for CTO revascularization. While several techniques, devices, and guide wires have been developed and refined for use in CTOs, the...

journal_title：European heart journal

authors： Courtney BK,Munce NR,Anderson KJ,Thind AS,Leung G,Radau PE,Foster FS,Vitkin IA,Schwartz RS,Dick AJ,Wright GA,Strauss BH

更新日期：2008-03-01 00:00:00

abstract：:In the present study 27 post-myocardial infarction patients were treated with Persantin capsules (Depot-Kapseln, sustained release form), containing 200 mg dipyridamole, b.i.d. over a period of 3 weeks. Baseline levels for plasma beta-thromboglobulin (BTG), platelet factor 4 (PF4), and serum thromboxane B2 (TXB2) were...

journal_title：European heart journal

authors： Safai-Kutti S,Kutti J,Vedin A,Wilhelmsson C

更新日期：1985-06-01 00:00:00

abstract：AIMS:Non-vitamin K antagonist oral anticoagulants (NOACs) require dose reductions according to patient or clinical factors for patients with atrial fibrillation (AF). In this meta-analysis, we aimed to assess outcomes with reduced-dose NOACs when given as pre-specified in pivotal trials. METHODS AND RESULTS:Aggregated...

journal_title：European heart journal

authors： Wang KL,Lopes RD,Patel MR,Büller HR,Tan DS,Chiang CE,Giugliano RP

更新日期：2019-05-14 00:00:00

abstract：AIMS:Periconceptional folate supplementation prevents neural tube defects and possibly congenital heart defects (CHD) as well. The search for candidate genes involved in the folate metabolism includes the methylenetetrahydrofolate reductase (MTHFR) 677C > T polymorphism. We studied the association between MTHFR 677C > ...

journal_title：European heart journal

authors： van Beynum IM,Kapusta L,den Heijer M,Vermeulen SH,Kouwenberg M,Daniëls O,Blom HJ

更新日期：2006-04-01 00:00:00

abstract：:Out of 84,609 Europeans in the ERICA sample (EHJ 9, Suppl I) 18,931 had adequate 6-year follow-up data so that coronary heart disease (CHD) mortality could be assessed in relation to five risk factors (age, cholesterol, systolic blood pressure, body mass index and cigarette smoking) measured at baseline. In view of kn...

journal_title：European heart journal

authors：

更新日期：1991-03-01 00:00:00

abstract：AIMS:Our objective was to create a simple prognostic risk score for patients with systolic heart failure and mild symptoms. We then assessed the efficacy of eplerenone across different categories of risk. METHODS AND RESULTS:The Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure trial (EMP...

journal_title：European heart journal

authors： Collier TJ,Pocock SJ,McMurray JJ,Zannad F,Krum H,van Veldhuisen DJ,Swedberg K,Shi H,Vincent J,Pitt B

更新日期：2013-09-01 00:00:00

abstract：:In 103 hearts with various forms of cardiac muscle hypertrophy the following parameters were estimated: diameter, length, volume, density and number of myocytes, and density of myocyte nuclei. The values of all histometric parameters correlated well with left ventricular (LV) weight up to 350 g. In heavier hearts thes...

journal_title：European heart journal

authors： Grajek S,Lesiak M,Pyda M,Zajac M,Paradowski S,Kaczmarek E

更新日期：1993-01-01 00:00:00

abstract：:The role of ventricular rate-adaptive pacing (VVIR) in the elderly was investigated in 12 patients with a mean age of 85 +/- 2 years (range 75-95 years) with implanted activity-initiated VVIR pacemakers. Although four patients had significant extracardiac diseases, all were capable of independent walking and self care...

journal_title：European heart journal

authors： Lau CP,Wong CK,Tai YT,Fong PC,Li JP,Chung FL

更新日期：1992-07-01 00:00:00

abstract：AIMS:Recent randomized clinical trials have reported a reduction in restenosis with intracoronary stents and have suggested that this restenosis reduction is a result of the higher immediate luminal gain, in comparison to conventional percutaneous transluminal coronary angioplasty (PTCA). The hypothesis of this study i...

journal_title：European heart journal

authors： Haase KK,Athanasiadis A,Mahrholdt H,Treusch A,Wullen B,Jaramillo C,Baumbach A,Voelker W,Meisner C,Karsch KR

更新日期：1998-02-01 00:00:00

abstract：AIMS:Genome-wide association studies have previously identified INSIG2 as a candidate gene for plasma low-density lipoprotein cholesterol (LDL-c). However, we suspect a role for CCDC93 in the same locus because of its involvement in the recycling of the LDL-receptor (LDLR). METHODS AND RESULTS:Characterization of the ...

journal_title：European heart journal

authors： Rimbert A,Dalila N,Wolters JC,Huijkman N,Smit M,Kloosterhuis N,Riemsma M,van der Veen Y,Singla A,van Dijk F,Biobank-Based Integrative Omics Studies Consortium.,Frikke-Schmidt R,Burstein E,Tybjærg-Hansen A,van de Sluis B,Kui

更新日期：2020-03-01 00:00:00

abstract：AIMS:To assess safety, feasibility and short term outcome of pulmonary vein (PV) isolation in paroxysmal atrial fibrillation (AF) with a cryoballoon. METHODS:We consecutively treated 57 patients with a double lumen 23 or 28 mm cryoballoon. The acute results, complications and follow-up over the first three months were...

journal_title：European heart journal

authors： Van Belle Y,Janse P,Rivero-Ayerza MJ,Thornton AS,Jessurun ER,Theuns D,Jordaens L

更新日期：2007-09-01 00:00:00

abstract：AIMS:To investigate whether Atorvastatin (Ator) treatment improves the cardiac micro-environment that facilitates survival and differentiation of bone-marrow-derived mesenchymal stem cells (MSCs) implanted in the post-infarct myocardium. METHODS AND RESULTS:Myocardial infarction was created by coronary ligation and im...

journal_title：European heart journal

authors： Yang YJ,Qian HY,Huang J,Geng YJ,Gao RL,Dou KF,Yang GS,Li JJ,Shen R,He ZX,Lu MJ,Zhao SH

更新日期：2008-06-01 00:00:00

abstract：AIMS:Anecdotal observations suggest that sub-clinical electrophysiological manifestations of arrhythmogenic right ventricular cardiomyopathy (ARVC) develop before detectable structural changes ensue on cardiac imaging. To test this hypothesis, we investigated a murine model with conditional cardiac genetic deletion of ...

journal_title：European heart journal

authors： Gomes J,Finlay M,Ahmed AK,Ciaccio EJ,Asimaki A,Saffitz JE,Quarta G,Nobles M,Syrris P,Chaubey S,McKenna WJ,Tinker A,Lambiase PD

更新日期：2012-08-01 00:00:00

abstract：:In the blood-vessel wall, the endothelium plays a key functional role by generating several substances that modulate vascular smooth muscle tone, as well as growth, and platelet function. This review focuses on the role of the endothelial L-arginine/nitric oxide signal transduction pathway in the maintenance of vascul...

journal_title：European heart journal

authors： Cosentino F,Lüscher TF

更新日期：1995-11-01 00:00:00

abstract：:During a 3-year period 2500 asymptomatic male aviators were screened routinely for coronary artery disease by maximal bicycle exercise testing. In 55 cases (2.1%) the exercise ECG was abnormal (40 subjects exhibited ST depression, 14 ventricular ectopic activity and in one subject both abnormalities were observed). Fu...

journal_title：European heart journal

authors： Pedersen F,Sandøe E,Laerkeborg A

更新日期：1991-07-01 00:00:00

abstract：:Coronary heart disease (CHD) is the leading cause of death and disability in Europe. For patients presenting with an acute ST-segment elevation myocardial infarction (STEMI), timely myocardial reperfusion using either thrombolytic therapy or primary percutaneous coronary intervention (PPCI) is the most effective thera...

journal_title：European heart journal

authors： Fröhlich GM,Meier P,White SK,Yellon DM,Hausenloy DJ

更新日期：2013-06-01 00:00:00

abstract：:Atrial fibrillation (AF) and chronic heart failure (CHF) are two major and even growing cardiovascular conditions that often coexist. However, few data are available to guide treatment of AF in patients with CHF. This review summarizes current literature concerning the following topics: (i) prognostic relevance of AF ...

journal_title：European heart journal

authors： Neuberger HR,Mewis C,van Veldhuisen DJ,Schotten U,van Gelder IC,Allessie MA,Böhm M

更新日期：2007-11-01 00:00:00

abstract：:The haemodynamic effects of intravenous frusemide (1 mg/kg) were studied in 22 male patients with left ventricular failure following acute myocardial infarction. Radiographic pulmonary oedema was present in all patients and their average left heart filling pressure was 20 mmHg. Bolus injection of the drug was followed...

journal_title：European heart journal

authors： Nelson GI,Ahuja RC,Silke B,Okoli RC,Hussain M,Taylor SH

更新日期：1983-10-01 00:00:00

abstract：AIMS:Here, we aimed to determine the therapeutic effect of longevity-associated variant (LAV)-BPIFB4 gene therapy on atherosclerosis. METHODS AND RESULTS:ApoE knockout mice (ApoE-/-) fed a high-fat diet were randomly allocated to receive LAV-BPIFB4, wild-type (WT)-BPIFB4, or empty vector via adeno-associated viral vec...

journal_title：European heart journal

authors： Puca AA,Carrizzo A,Spinelli C,Damato A,Ambrosio M,Villa F,Ferrario A,Maciag A,Fornai F,Lenzi P,Valenti V,di Nonno F,Accarino G,Madonna M,Forte M,Calì G,Baragetti A,Norata GD,Catapano AL,Cattaneo M,Izzo R,Trimarc

更新日期：2020-07-07 00:00:00

abstract：BACKGROUND:Stent thrombosis (ST) is a rare but serious complication following percutaneous coronary intervention. Analysis of thrombus composition from patients undergoing catheter thrombectomy may provide important insights into the pathological processes leading to thrombus formation. We performed a large-scale multi...

journal_title：European heart journal

authors： Riegger J,Byrne RA,Joner M,Chandraratne S,Gershlick AH,Ten Berg JM,Adriaenssens T,Guagliumi G,Godschalk TC,Neumann FJ,Trenk D,Feldman LJ,Steg PG,Desmet W,Alfonso F,Goodall AH,Wojdyla R,Dudek D,Philippi V,Opinaldo S

更新日期：2016-05-14 00:00:00

abstract：AIM:Ventricular fibrillation (VF), the main cause of sudden cardiac death (SCD), occurs most frequently in the acute phase of myocardial infarction: a certain fraction of VF, however, develops in an apparently healthy heart, referred as idiopathic VF. The contribution of perturbation in the fast conduction system in th...

journal_title：European heart journal

authors： Koizumi A,Sasano T,Kimura W,Miyamoto Y,Aiba T,Ishikawa T,Nogami A,Fukamizu S,Sakurada H,Takahashi Y,Nakamura H,Ishikura T,Koseki H,Arimura T,Kimura A,Hirao K,Isobe M,Shimizu W,Miura N,Furukawa T

更新日期：2016-05-07 00:00:00

abstract：BACKGROUND:Oral dipyridamole induces accumulation of endogenous adenosine, which in a hypoxic milieu exerts experimentally an angiogenic effect on coronary collateral circulation. A meta-analysis of 13 randomized placebo-controlled trials published between 1960 and 1992 showed evidence of benefit for dipyridamole in th...

journal_title：European heart journal

authors： Picano E,PISA (Persantin In Stable Angina) study group.

更新日期：2001-10-01 00:00:00

abstract：:To evaluate gender-related differences in left ventricular (LV) structure and function in aortic stenosis, LV biplane cineangiography, micromanometry and endomyocardial biopsies were carried out in 56 patients with aortic stenosis and normal coronary arteries. Patients were divided into males (M: n = 35), and females ...

journal_title：European heart journal

authors： Villari B,Campbell SE,Schneider J,Vassalli G,Chiariello M,Hess OM

更新日期：1995-10-01 00:00:00