Abstract:
:The scyllo-inositol and myo-inositol concentrations of 24 normal human subjects were measured in vivo using 1H magnetic resonance spectroscopy at 4 T. Single-voxel short-echo (TE = 15 ms) metabolite spectra were collected from the white matter region of the corona radiata. Test-retest studies performed on 10 normal subjects demonstrated coefficient of variation for scyllo-inositol measurement of 37%, compared with 6% for N-acetyl aspartate. Comparisons between old and young subjects showed higher concentration of scyllo-inositol and myo-inositol in older subjects and a trend for a correlation between scyllo-inositol and myo-inositol levels across subjects.
journal_name
NMR Biomedjournal_title
NMR in biomedicineauthors
Kaiser LG,Schuff N,Cashdollar N,Weiner MWdoi
10.1002/nbm.927subject
Has Abstractpub_date
2005-02-01 00:00:00pages
51-5issue
1eissn
0952-3480issn
1099-1492journal_volume
18pub_type
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