Analysis of acyl CoA ester intermediates of the mevalonate pathway in Saccharomyces cerevisiae.

abstract：:The 3D structures of Fim H and PapG proteins complexed with the host carbohydrate receptor demonstrate that both utilize binding-pocket asparagines for contact or stabilization with the carbohydrate. Pretreatment of whole bacteria with asparaginase resulted in decreased fimbriae-mediated attachment to urinary epitheli...

journal_title：Applied microbiology and biotechnology

authors： Wehner MR,Koch SR,Kindinger L,Nelson N,Cowan MM

更新日期：2004-11-01 00:00:00

abstract：:Endophytic actinobacteria, which exist in the inner tissues of living plants, have attracted increasing attention among taxonomists, ecologists, agronomists, chemists and evolutionary biologists. Numerous studies have indicated that these prolific actinobacteria appear to have a capacity to produce an impressive array...

journal_title：Applied microbiology and biotechnology

authors： Qin S,Xing K,Jiang JH,Xu LH,Li WJ

更新日期：2011-02-01 00:00:00

abstract：:The aim of this study was to discover new nitrilases with useful activities, especially towards dinitriles that are precursors of high-value cyano acids. Genes coding for putative nitrilases of different origins (fungal, plant, or bacterial) with moderate similarities to known nitrilases were selected by mining the Ge...

journal_title：Applied microbiology and biotechnology

authors： Veselá AB,Rucká L,Kaplan O,Pelantová H,Nešvera J,Pátek M,Martínková L

更新日期：2016-03-01 00:00:00

abstract：:The ability to produce (R)- or (S)-beta-phenylalanine ethyl ester (3-amino-3-phenylpropionic acid ethyl ester, BPAE) from racemic BPAE through stereoselective hydrolysis was screened for in BPAE-assimilating microorganisms. Sphingobacterium sp. 238C5 and Arthrobacter sp. 219D2 were found to be potential catalysts for ...

journal_title：Applied microbiology and biotechnology

authors： Ogawa J,Mano J,Shimizu S

更新日期：2006-05-01 00:00:00

abstract：:Influence of pressure (P) and oxygen partial pressure (PO2) on cultivation of various Streptomyces spp. and Micromonospora purpurea was examined in pressurized air-lift and stirred tank fermenters. The maximum PO2 was 2100 mbar. Growth and product formation of all cultures tested were markedly influenced by PO2 higher...

journal_title：Applied microbiology and biotechnology

authors： Liefke E,Kaiser D,Onken U

更新日期：1990-03-01 00:00:00

abstract：:Two-stage technologies have been developed for anaerobic digestion of waste-activated sludge. In this study, the archaeal and bacterial community structure dynamics and bioprocess performance of a bench-scale two-stage anaerobic digester treating urban sewage sludge have been studied by the means of high-throughput se...

journal_title：Applied microbiology and biotechnology

authors： Gonzalez-Martinez A,Garcia-Ruiz MJ,Rodriguez-Sanchez A,Osorio F,Gonzalez-Lopez J

更新日期：2016-07-01 00:00:00

abstract：:The novel influenza A virus (IAV) defective interfering particle "OP7" inhibits IAV replication in a co-infection and was previously suggested as a promising antiviral agent. Here, we report a batch-mode cell culture-based production process for OP7. In the present study, a seed virus containing standard virus (STV) a...

journal_title：Applied microbiology and biotechnology

authors： Hein MD,Kollmus H,Marichal-Gallardo P,Püttker S,Benndorf D,Genzel Y,Schughart K,Kupke SY,Reichl U

更新日期：2021-01-01 00:00:00

abstract：:Homologous recombination-based recombineering is a widely used DNA cloning and modification technique; recombineering efficiency improvement would be helpful for high-throughput DNA manipulation. Escherichia coli primase DnaG variants, such as DnaG Q576A and DnaG K580A, increase the recombineering efficiency via impai...

journal_title：Applied microbiology and biotechnology

authors： Li J,Sun J,Gao X,Wu Z,Shang G

更新日期：2019-04-01 00:00:00

abstract：:Hemidesmus indicus (L.) R. Br. ex Schult., commonly known as Indian sarsaparilla or Anantamul, is an ethnopharmacologically important medicinal plant from the family Apocynaceae. Biosynthesis of an array of bioactive compounds such as methoxybenzaldehydes and their derivatives has been accountable for its intensive me...

journal_title：Applied microbiology and biotechnology

authors： Nandy S,Singh J,Pandey DK,Dey A

更新日期：2020-10-01 00:00:00

abstract：:The photocatalytic properties of titanium dioxide are well known and have many applications including the removal of organic contaminants and production of self-cleaning glass. There is an increasing interest in the application of the photocatalytic properties of TiO(2) for disinfection of surfaces, air and water. Rev...

journal_title：Applied microbiology and biotechnology

authors： Foster HA,Ditta IB,Varghese S,Steele A

更新日期：2011-06-01 00:00:00

abstract：:Neuritin (also known as candidate plasticity gene 15 (cpg15)) is a neurotrophic factor that was recently discovered in a screen aimed at identifying genes involved in activity-dependent synaptic plasticity. Neuritin plays multiple roles in both neural development (Chen et al. Zhonghua Yan Ke Za Zhi 46:978-983 2010; Co...

journal_title：Applied microbiology and biotechnology

authors： Zhang Y,Zhang S,Xian L,Tang J,Zhu J,Cui L,Li S,Yang L,Huang J

更新日期：2015-10-01 00:00:00

abstract：:Porcine circovirus type 3 (PCV3) is an emerging swine pathogen associated with acute porcine dermatitis and nephropathy syndrome (PDNS)-like clinical signs, reproductive failure, and multisystemic inflammation. Current evidence shows that PCV3 is spread worldwide, and its high incidence may pose a threat to the global...

journal_title：Applied microbiology and biotechnology

authors： Jiang M,Guo J,Zhang G,Jin Q,Liu Y,Jia R,Wang A

更新日期：2020-07-01 00:00:00

abstract：:Bacteria that grow on p-xylene, p-toluic acid, and terephthalic acid (TPA) were isolated from a wastewater bioreactor that is used to treat a waste stream that contains all three of these compounds. Although previously described aerobic bacteria degrade p-xylene by initially oxidizing a single methyl group to form p-t...

journal_title：Applied microbiology and biotechnology

authors： Bramucci MG,McCutchen CM,Singh M,Thomas SM,Larsen BS,Buckholz J,Nagarajan V

更新日期：2002-02-01 00:00:00

abstract：:The internal loop photobiodegradation reactor (ILPBR) was evaluated for the degradation of the pharmaceutical sulfamethoxazole (SMX) using batch experiments following three protocols: photolysis alone (P), biodegradation alone (B), and intimately coupled photolysis and biodegradation (P&B). SMX was removed more rapidl...

journal_title：Applied microbiology and biotechnology

authors： Yan N,Xia S,Xu L,Zhu J,Zhang Y,Rittmann BE

更新日期：2012-04-01 00:00:00

abstract：:Streptomyces coelicolor A3(2) is a rubber-degrading actinomycete that harbors one gene coding for a latex clearing protein (lcpA3(2)). Within the genome of S. coelicolor A3(2), we identified a gene coding for a novel protein of the TetR family (LcpRBA3(2)) downstream of lcpA3(2) and demonstrated its binding upstream o...

journal_title：Applied microbiology and biotechnology

authors： Coenen A,Oetermann S,Steinbüchel A

更新日期：2019-07-01 00:00:00

abstract：:Potentiometric biosensors for the determination of organophosphorus (OP) insecticides were developed by applying either immobilized whole cells or cytoplasmic membrane fractions of wild-type Flavobacterium sp. on the surface of a glass pH electrode. The ability of Flavobacterium sp. to degrade OP compounds as sole car...

journal_title：Applied microbiology and biotechnology

authors： Gäberlein S,Spener F,Zaborosch C

更新日期：2000-11-01 00:00:00

abstract：:Despite current remediation efforts, arsenic contamination in water sources is still a major health problem, highlighting the need for new approaches. In this work, strains of the nonpathogenic and highly arsenic-resistant bacterium Corynebacterium glutamicum were used as inexpensive tools to accumulate inorganic arse...

journal_title：Applied microbiology and biotechnology

authors： Villadangos AF,Ordóñez E,Pedre B,Messens J,Gil JA,Mateos LM

更新日期：2014-12-01 00:00:00

abstract：:Cultures of Microcoleus consortia polluted with two different types of crude oil, one with high content in aliphatic hydrocarbons (Casablanca) and the other rich in sulphur and aromatic compounds (Maya), were grown for 50 days and studied for changes in oil composition. No toxic effects from these oils were observed o...

journal_title：Applied microbiology and biotechnology

authors： De Oteyza TG,Grimalt JO,Diestra E,Solé A,Esteve I

更新日期：2004-12-01 00:00:00

abstract：:The process of nitrification has the potential for the in situ bioremediation of halogenated compounds provided a number of challenges can be overcome. In nitrification, the microbial process where ammonia is oxidized to nitrate, ammonia-oxidizing bacteria (AOB) are key players and are capable of carrying out the biod...

journal_title：Applied microbiology and biotechnology

authors： Sayavedra-Soto LA,Gvakharia B,Bottomley PJ,Arp DJ,Dolan ME

更新日期：2010-03-01 00:00:00

abstract：:Agrobacterium tumefaciens has been widely used as a tool for transgenesis in plants. The availability of its genome sequence should facilitate the directed engineering of improved properties; however, the current genome engineering options are laborious. Here, we investigated whether the lambda Red operon can be appli...

journal_title：Applied microbiology and biotechnology

authors： Hu S,Fu J,Huang F,Ding X,Stewart AF,Xia L,Zhang Y

更新日期：2014-03-01 00:00:00

abstract：:Genetic engineering of transcription factors is an efficient strategy to improve lignocellulolytic enzyme production in fungi. In this study, the xylanase transcriptional regulators of Trichoderma reesei (Xyr1) and Neurospora crassa (XLR-1), as well as their constitutively active mutants (Xyr1A824V and XLR-1A828V), we...

journal_title：Applied microbiology and biotechnology

authors： Xia C,Li Z,Xu Y,Yang P,Gao L,Yan Q,Li S,Wang Y,Qu Y,Song X

更新日期：2019-03-01 00:00:00

abstract：:Quorum sensing (QS) regulates virulence and biofilm formation in Pseudomonas aeruginosa and other medically relevant bacteria. Human paraoxonases (hPONs) are a family of closely related enzymes with multiple functions, including inactivation of the QS signal molecule in P. aeruginosa. However, there is no direct evide...

journal_title：Applied microbiology and biotechnology

authors： Ma F,Wang Y,Zhang Y,Xiong N,Yang B,Chen S

更新日期：2009-05-01 00:00:00

abstract：:Yeast is widely used in the baking, biocontrol, brewing, and bio manufacturing industries. In the baking industry alone, around two million tons of yeast are consumed worldwide every year. While yeast brings delicious and healthy lives to humans, we find that stress resistance of yeast is essential for the development...

journal_title：Applied microbiology and biotechnology

authors： Qiu X,Zhang J,Zhou J,Fang Z,Zhu Z,Li J,Du G

更新日期：2019-08-01 00:00:00

abstract：:Seven fractions rich in endoglucanase activity were separated from the extracellular cellulase system of the anaerobic rumen fungus Neocallimastix frontalis. The fractions (ES1, ES3, ES2U1, ES2U2, ES2U4, ES2U3C1 and ES2U3C2) were separated from each other and from a fraction that could solubilize crystalline cellulose...

journal_title：Applied microbiology and biotechnology

authors： Wood TM,Wilson CA,McCrae SI

更新日期：1995-12-01 00:00:00

abstract：:Bacillus cereus 905, one of the plant growth-promoting rhizobacteria (PGPRs), is capable of colonizing wheat roots in a large population size. From previous studies, we learned that the sodA2-encoding manganese-containing superoxide dismutase (MnSOD2) is important for B. cereus 905 to survive in wheat rhizosphere. In ...

journal_title：Applied microbiology and biotechnology

authors： Gao T,Ding M,Wang Q

更新日期：2020-11-01 00:00:00

abstract：:The recent use of photosynthetic organisms such as Chlamydomonas reinhardtii in biomedical applications has demonstrated their potential for the treatment of acute and chronic tissue hypoxia. Moreover, transgenic microalgae have been suggested as an alternative in situ drug delivery system. In this study, we set out t...

journal_title：Applied microbiology and biotechnology

authors： Jarquín-Cordero M,Chávez MN,Centeno-Cerdas C,Bohne AV,Hopfner U,Machens HG,Egaña JT,Nickelsen J

更新日期：2020-01-01 00:00:00

abstract：:Microbial genome sequencing has left a legacy of annotated yet uncharacterized genes or open reading frames, activities that may have useful applications in health and/or the environment. We are interested in the discovery and characterization of potentially new pectinolytic activities for the enzymatic retting of nat...

journal_title：Applied microbiology and biotechnology

authors： Xiao Z,Boyd J,Grosse S,Beauchemin M,Coupe E,Lau PC

更新日期：2008-04-01 00:00:00

abstract：:Penicillin G acylase from Achromobacter sp. (NPGA) was studied in the enzymatic synthesis of β-lactam antibiotics by kinetically controlled N-acylation. When compared with penicillin acylase of Escherichia coli (PGA), the NPGA was significantly more efficient at syntheses of ampicillin and amoxicillin (higher S/H rati...

journal_title：Applied microbiology and biotechnology

authors： Bečka S,Štěpánek V,Vyasarayani RW,Grulich M,Maršálek J,Plháčková K,Dobišová M,Marešová H,Plačková M,Valešová R,Palyzová A,Datla A,Ashar TK,Kyslík P

更新日期：2014-02-01 00:00:00

abstract：:Fungal interspecific interactions enhance biosynthesis of phenylpropanoid metabolites (PM), and production of nitric oxide (NO) is known to be involved in this process. However, it remains unknown which signaling pathway(s) or regulator(s) mediate fungal PM biosynthesis. In this study, we cocultured two white-rot fung...

journal_title：Applied microbiology and biotechnology

authors： Zhao Y,Xi Q,Xu Q,He M,Ding J,Dai Y,Keller NP,Zheng W

更新日期：2015-05-01 00:00:00

abstract：:Trichothecenes are toxic secondary metabolites produced by filamentous fungi mainly belonging to the Fusarium genus. Production of these mycotoxins occurs during infection of crops and is a threat to human and animal health. Although the pathway for biosynthesis of trichothecenes is well established, the regulation of...

journal_title：Applied microbiology and biotechnology

authors： Merhej J,Richard-Forget F,Barreau C

更新日期：2011-08-01 00:00:00