Abstract:
PRIMARY OBJECTIVE:The aim of this study was to assess skeletal muscle showing a complete functional recovery after induction of pan-necrotic lesions in the right sensorimotor cortex in rats. RESEARCH DESIGN AND METHODS:A focal lesion of the right sensorimotor cortex was induced photochemically. Rats were divided into three groups; the sham-operated group (CON), Stroke (RB) and Stroke plus severed right sciatic nerve (RBD). MAIN OUTCOMES AND RESULTS:All RB rats showed complete functional recovery in the beam-walking test within 10 days. The score of CON rats was 7 for 21 days. The wet weight of the soleus muscle (SOL) only in the RB and RBD was significantly greater than in the CON. The cross-sectional area of type I fibres was increased in SOL. CONCLUSIONS:It was concluded that the functional recovery was mainly due to increased wet weight and cross-sectional area of type I SOL fibres, which probably reflected the functional reorganization and neuromodulation in the non-damaged contralateral sensorimotor cortex and ipsilateral sensorimotor cortex lateral to the lesion identified in a previous study.
journal_name
Brain Injjournal_title
Brain injuryauthors
Abo M,Miyano S,Eun SS,Yamauchi Hdoi
10.1080/02699050410001672305subject
Has Abstractpub_date
2004-10-01 00:00:00pages
1017-24issue
10eissn
0269-9052issn
1362-301Xpii
PU8MCGYA3PVYNB5Yjournal_volume
18pub_type
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