Abstract:
OBJECTIVES:Traumatic brain injury (TBI) is an increasingly significant health concern worldwide, compounded by the difficultly in detection and diagnosis. Fortunately, a growing body of research has identified oculomotor behavior, specifically fixations, saccades and smooth pursuit eye movements as a promising endophenotype for neurotrauma. To date, limited research exists using fixation stability in a comparative study to indicate the presence of a mild TBI (mTBI), especially in the pediatric population. METHODS:The present study examined data from 91 individuals clinically diagnosed with mTBI and a further 140 age- and gender-matched controls. They all completed the RightEye fixation stability test using a remote eye tracker. Participants were compared on five fixation metrics: Bivariate Contour Ellipse Area (BCEA), Convergence Point, Depth, Disassociated Phoria, and Targeting Displacement. RESULTS:Results were analyzed using one-way univariate ANOVAs, ROC analysis, and stepwise logistic regression. BCEA results revealed significant differences between groups with the mTBI group showing a larger gaze spread, indicative of less ability to keep the eyes close to the target without deviating. CONCLUSIONS:Fixation stability is detrimentally impacted by mTBI in pediatric patients, and the oculomotor test can be used to differentiate between those with and without an mTBI.
journal_name
Brain Injjournal_title
Brain injuryauthors
Hunfalvay M,Murray NP,Carrick FRdoi
10.1080/02699052.2020.1865566subject
Has Abstractpub_date
2020-12-24 00:00:00pages
1-6eissn
0269-9052issn
1362-301Xpub_type
杂志文章相关文献
BRAIN INJURY文献大全abstract::Traumatic brain injury (TBI) is the leading cause of death and permanent disability in children and adolescents. Although cognitive and behavioural effects have now been reported for all degrees of TBI severity in children, other aspects of functioning which might be related (such as psychosocial adjustment), have bee...
journal_title:Brain injury
pub_type: 临床试验,杂志文章
doi:10.1080/026990598122755
更新日期:1998-02-01 00:00:00
abstract::Background: The Convergence Insufficiency Symptom Survey (CISS) is being utilized as an assessment measure following concussion despite minimal research. This study explored the sensitivity and specificity of the CISS in identifying receded near point of convergence (NPC) post-concussion. Methods: Prospective study of...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699052.2019.1658131
更新日期:2019-01-01 00:00:00
abstract::In a simulated functional task involving comprehension of a spoken passage, the performance of 20 traumatically brain-injured and 14 non-brain-injured control patients was compared under conditions which included the presence and absence of competing vocal stimuli. The subjects heard 10 target paragraphs which were ap...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699058809150937
更新日期:1988-04-01 00:00:00
abstract:OBJECTIVE:To report a case of brain injury following neuroleptic malignant syndrome (NMS) and review the literature for similar documented cases. CASE REPORT:A 30-year old woman presented to the ER with psychotic features and was treated with several anti-psychotics. Subsequently, she developed neurological symptoms a...
journal_title:Brain injury
pub_type: 杂志文章,评审
doi:10.1080/02699050600663022
更新日期:2006-06-01 00:00:00
abstract::Aim: To investigate the association of periodontitis to orofacial health-related systemic impairment in patients with acquired brain injury (ABI). Methods: Ninety individuals with ABI were included. Full mouth periodontal examination was performed. Orofacial health-related 'motor' and 'cognitive' scores, dysphagia and...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699052.2020.1858497
更新日期:2020-12-14 00:00:00
abstract:OBJECTIVE:Traumatic brain injury (TBI) is the leading cause of death and permanent disability in developmental age. Neurobehavioural symptoms are not uncommon in these patients. The aim of this study was to identify the main neuropsychiatric sequelae of TBI at different ages and study the possible correlations with cli...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/0269905031000088612
更新日期:2003-10-01 00:00:00
abstract::Introduction: Blood-based biomarkers can provide valuable information on the effects of repetitive head impacts in sports. This study investigated if repetitive headers or accidental head impacts in soccer could cause structural brain injury, detected as an increase in serum neurofilament light (NfL) or tau.Methods: N...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699052.2020.1725129
更新日期:2020-04-15 00:00:00
abstract::This study reports the improvement of verbal interaction skills in a 27-year-old severely head-injured male who presented with an inappropriate attention-seeking circumlocutory conversational style. The patient was baselined on verbal response to three differing question forms, and then treated using combined cognitiv...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699058809150933
更新日期:1988-01-01 00:00:00
abstract:PRIMARY OBJECTIVE:To explore whether baseline diffusion tensor imaging (DTI) metrics are predictive of cognitive functioning 6 months post-injury in patients with mild traumatic brain injury (MTBI). RESEARCH DESIGN:Seventeen patients with MTBI and 29 sex- and age-matched healthy controls were studied. METHODS AND PRO...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699050801888816
更新日期:2008-02-01 00:00:00
abstract:AIM:The present study aimed to examine the nature of attention distinctions among sub-tests of the Test of Everyday Attention (TEA) underlying the performance of patients with traumatic brain injury (TBI). METHOD:Confirmatory factor analysis was performed among a group of 92 patients with TBI experiencing chronic post...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699050600676974
更新日期:2006-06-01 00:00:00
abstract::This study compared the psychophysiological parameters involved in the processing of bisensory memory tasks and their recall in a group of 30 adult patients with closed head injury and a group of 29 normal controls. Utilizing an automated on-line computerized system, continuous recording of heart rate, galvanic skin r...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699058709034455
更新日期:1987-10-01 00:00:00
abstract::Objective: To investigate differences in frequent pain or headaches and associated neurobehavioral symptoms among men, women, and transgender individuals with and without a history of traumatic brain injury (TBI). Setting: Community Participants: English and Spanish-speaking adults (n = 2,862) with and without self-re...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699052.2020.1857438
更新日期:2021-01-04 00:00:00
abstract::Shorter inpatient stays for traumatically brain injured patients frequently allow less time for comprehensive education of families and caretakers. What is needed to compensate for the shortened duration of brain injury rehabilitation in many settings is a family educational programme that (1) satisfies the family's a...
journal_title:Brain injury
pub_type:
doi:10.1080/026990598121918
更新日期:1998-12-01 00:00:00
abstract::Early rehabilitation has been shown to minimize complications and optimize functional outcomes in head-injured patients. Although cognitive, behavioural and vocational issues continue for years after injury, many investigations maintain that physical improvement is limited after 6 months. At 12 months after injury, ex...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699059209034951
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:Introduced in the 1980s, the neurofunctional approach (NFA) is one of the few interventions designed primarily for clients with severe deficits following traumatic brain injury (TBI). Specifically the NFA was intended for those individuals who were limited in their ability to solve novel problems or generali...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699052.2014.946449
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:Validation of a new screening tool, viz., the Brain Injury Alert (BI Alert) for identification of cognitive and emotional problems after traumatic brain injury (TBI) in children. METHODS:Parents and teachers of children with TBI as well as controls were interviewed using the BI Alert. Validity was determined u...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699052.2011.580311
更新日期:2011-01-01 00:00:00
abstract::We report a patient who exhibited Gerstmann's syndrome in association with a chronic subdural haematoma. A 71-year-old right-handed woman presented with mild right arm and leg weakness that began 2 weeks prior to admission. Neurological examination on admission revealed a mild right hemiparesis. Neuropsychological exa...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/026990598122250
更新日期:1998-08-01 00:00:00
abstract::Objective: The goal is to evaluate longitudinally with diffusion tensor imaging (DTI) the integrity of cerebral white matter in patients with moderate and severe DAI and to correlate the DTI findings with cognitive deficits. Methods: Patients with DAI (n = 20) were scanned at three timepoints (2, 6 and 12 months) afte...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699052.2020.1859615
更新日期:2021-01-28 00:00:00
abstract:BACKGROUND:The apolipoprotein E gene (APOE) has emerged as a candidate for prognosticating traumatic brain injury (TBI) recovery, with APOEε4 identified as a susceptibility marker for poor outcome, despite large discrepancy in its reported influence post-TBI. METHODS:A systematic review was conducted, including all pr...
journal_title:Brain injury
pub_type: 杂志文章,评审
doi:10.3109/02699052.2015.1005131
更新日期:2015-01-01 00:00:00
abstract::While movement disorders are frequently encountered after brain injuries, and may create a host of complicated problems for the clinician, only a few cases of Parkinsonism associated with hydrocephalus have ever been described in the literature. Parkinsonism-like syndrome complicating hydrocephalus is a rare disorder,...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/026990597123043
更新日期:1997-11-01 00:00:00
abstract:PRIMARY OBJECTIVE:The purpose of this study was to assess the relationship between sex and traumatic brain injury (TBI) mortality. METHODS AND PROCEDURES:A total of 20,465 persons with TBI were identified from a Colorado population-based surveillance system for 1994-1998. Case fatality ratios were calculated to identi...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699050500488058
更新日期:2006-03-01 00:00:00
abstract::Astrocytic subtypes in different cortical regions of injured human cerebral cortex of 22 patients with brain trauma, vascular anomalies and brain tumours have been examined by means of light microscopy and conventional transmission electron microscopy. The cortical biopsies of frontal, parietal and temporal cortex wer...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/026990599121665
更新日期:1999-04-01 00:00:00
abstract:PRIMARY OBJECTIVE:To determine the utility of the CAGE, the Brief Michigan Alcohol Screening Test (BMAST) and the Substance Abuse Subtle Screening Inventory (SASSI-3) with individuals with traumatic brain injury (TBI), two studies were conducted examining the accuracy, sensitivity and specificity of these instruments. ...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/0269905031000149506
更新日期:2004-02-01 00:00:00
abstract::A case is described of repetitive familiar activities apparently accompanied by a hallucinated physical environment in an older brain-injured man with an amputation of the left temporal lobe. A parallel is drawn to the 'experiential hallucinations' described in psychomotor seizures and direct stimulation of the cortex...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699059509004576
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To longitudinally examine objective and self-reported outcomes for recovery of cognition, communication, mood and participation in adults with traumatic brain injury (TBI) and co-morbid post-traumatic sleep/wake disorders. DESIGN:Prospective, longitudinal, single blind outcome study. SETTING:Community-based...
journal_title:Brain injury
pub_type: 临床试验,杂志文章
doi:10.3109/02699052.2013.823663
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of donepezil on cognitive ability in patients who have sustained a traumatic brain injury (TBI). We hypothesized that donepezil, an acetylcholinesterase inhibitor, would enhance cognitive recovery beyond that of usual care in an acute rehabilitation facility. METHODS:This retrospect...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699052.2018.1468574
更新日期:2018-01-01 00:00:00
abstract::Impairments in judging and responding to consequences that follow behaviour are often attributed to changes in various cognitive processes. An alternative conceptualization is that impairments may produce a reduction in sensitivity to reinforcement contingencies. The present investigation employed a methodology common...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/026990500120475
更新日期:2000-06-01 00:00:00
abstract::It has been shown in a previous study that head injured patients appear to have a circadian rhythm of their body functions. This needed to be confirmed using additional data, better collection methods and analysis. Additional goals were to develop a method of detrending of physiological time series in order to improve...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699050010007515
更新日期:2001-06-01 00:00:00
abstract::This paper describes the psychological dynamics among family members of patients with prolonged coma. We discuss the conflicts these families meet and how they affect their interpersonal relationships. Special focus is placed on overt and covert aggression towards the attending staff, an issue that has not received mu...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699058809150951
更新日期:1988-07-01 00:00:00
abstract::Animal models have been used to simulate the effects of human head trauma. Some of these models have been further utilized to explore how trauma affects specific mechanisms of synaptic plasticity, a cellular model for memory consolidation. Unfortunately, these studies have been more limited in number in spite of their...
journal_title:Brain injury
pub_type: 杂志文章,评审
doi:10.1080/0269905031000107142
更新日期:2003-08-01 00:00:00