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Pilot study on the use of psychotropic medication in persons with mental retardation.

Abstract：

OBJECTIVE:To explore the status of the psychotropic medication in persons with mental retardation 6 years after their deinstitutionalization. METHOD:The authors compared the profiles of psychotropic medication of 60 persons with mental retardation deinstitutionalized (D-sample) from our local mental hospital 6 years ago, to their actual pharmacological profile. Later, we compared our results to the ones of persons with mental retardation on an in-patient (In-sample) unit where existed a concerted team effort to lower the medication when deemed appropriate. RESULTS:Six years post-deinstitutionalization, the authors observed that the same percentage of patients remained on antipsychotic and benzodiazepine medication in our D-sample, and a threefold increase of those using antidepressive medication. However, we observe a general decrease of all types of psychotropic medication in the In-sample with complete withdrawal in a substantial number of patients. CONCLUSIONS:The authors take these pilot data to mean that a concerted team effort at lowering medication in persons with mental retardation makes a significant difference. The possibility of other factors (age, sex, severity of mental retardation, psychiatric diagnosis) explaining the difference in the results is discussed.

journal_name

Prog Neuropsychopharmacol Biol Psychiatry

journal_title

Progress in neuro-psychopharmacology & biological psychiatry

authors

Radouco-Thomas M,Bolduc M,Brisson A,Brassard P,Fortier L,Thivierge J

doi

10.1016/j.pnpbp.2004.05.029

subject

Has Abstract

pub_date

2004-08-01 00:00:00

pages

879-83

issue

5

eissn

0278-5846

issn

1878-4216

pii

S0278-5846(04)00087-9

journal_volume

28

pub_type

临床试验,杂志文章

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