Abstract:
OBJECTIVES:To determine the clinical presentation, findings, and outcomes of older adults (> 60) with severe acute respiratory syndrome (SARS) and compare these with a control group of younger patients (< or or =60). DESIGN:Retrospective cohort study. SETTING:A community-based, acute hospital in Hong Kong. PARTICIPANTS:All adult inpatients with a clinical diagnosis of SARS. MEASUREMENTS:Clinical presentations, investigations, treatment, and 30- and 150-day mortality. RESULTS:There were 52 young and 25 older patients with a mean age +/- standard deviation of 39.5+/-11.7 and 72.1+/-7.2, respectively. Fever, chills, and diarrhea were more common in younger patients, whereas decrease in appetite and general condition occurred only in older patients. The prevalence of positive reverse-transcriptase polymerase chain reaction for SARS-associated coronavirus (SARS-CoV) in nasopharyngeal secretions and stool samples was similar in the two groups. The prevalence of positive serological tests for SARS-CoV was significantly lower in older patients (42% vs 92%, P<.001). This was largely due to incomplete testing in elderly patients. Older patients were more likely to develop secondary nosocomial infection, be admitted to an intensive care unit, and require mechanical ventilation. The cumulative 30- and 150-day mortality rates were 3.8% and 7.6%, respectively, in young patients with SARS and 56% and 60%, respectively, in older patients (P<.001). CONCLUSION:Older patients with SARS more often presented with nonspecific symptoms, and the prognosis was poor. Reverse-transcriptase polymerase chain reaction was useful in diagnosing SARS in older patients, but the role of serological tests in individual elderly is limited.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Chan TY,Miu KY,Tsui CK,Yee KS,Chan MHdoi
10.1111/j.1532-5415.2004.52362.xsubject
Has Abstractpub_date
2004-08-01 00:00:00pages
1321-5issue
8eissn
0002-8614issn
1532-5415pii
JGS52362journal_volume
52pub_type
杂志文章abstract::Chief residents (CRs) play a crucial role in training residents and students but may have limited geriatrics training or formal preparation for their CR role. A 2-day off-site chief resident immersion training (CRIT) addressed these challenges. Objectives were to foster collaboration between disciplines in the managem...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2008.01710.x
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVES:To understand the range of symptoms that present to family caregivers of community-dwelling persons with Alzheimer's disease and related dementias (ADRD). DESIGN:Six-month longitudinal prospective study to identify the incidence of new or worsening symptoms and their association with acute care medical serv...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.14672
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVES:To investigate the natural history, cause of death, and end-of-life experiences of individuals diagnosed with dementia with Lewy bodies (DLB). DESIGN:Twenty-question online survey administered through the Lewy Body Dementia Association. SETTING:United States. PARTICIPANTS:Caregivers, family, and friends o...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15608
更新日期:2019-01-01 00:00:00
abstract::As part of a study of long-term institutional care of the elderly, this report presents salient data concerning 193 elderly applicants. Physicians play an important role in decisions to apply for such care. More than half of the applicants and about 80% of their family members approved of the proposed move. The number...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1976.tb04293.x
更新日期:1976-04-01 00:00:00
abstract::The loss of muscle mass during aging has been termed sarcopenia. Sarcopenia results in a decrease in physical strength during aging that results in important consequences for more severely affected individuals in terms of function and as a marker for disability and increased mortality. Despite the clinical importance ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.2004.52320.x
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVES:To systematically review the current literature on the pharmacological treatment of postmeal reductions in blood pressure (BP). DESIGN:A systematic literature search and standardized data collection of randomized controlled trials on the pharmacological prevention of postprandial reductions in BP in adults ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/jgs.12728
更新日期:2014-04-01 00:00:00
abstract::In a 78-year-old woman receiving perhexiline maleate for intractable angina pectoris, a syndrome of parkinsonism and peripheral neuropathy developed. The neuropathy was confirmed by electromyographic and nerve conduction studies. The parkinsonism and peripheral neuropathy disappeared when perhexiline maleate was disco...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1981.tb02188.x
更新日期:1981-06-01 00:00:00
abstract:OBJECTIVE:To determine whether low serum B12 levels are associated with an increased incidence of dementing illness. DESIGN:Longitudinal cohort study, 5-year follow-up. PARTICIPANTS:Volunteer cohort of 410 nondemented ambulatory subjects aged 75 to 85 years. MEASUREMENTS:Annual serum B12 determinations and neuropsyc...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1994.tb06583.x
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVES:To identify differences in cognitive function between elderly adults with sleep apnea syndrome (SAS) and healthy controls. DESIGN:Cross-sectional. SETTING:Sleep laboratory at Seoul National University Bundang Hospital. PARTICIPANTS:Sixty-three elderly adults (26 female; mean age 68.2 ± 4.8) without cognit...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2012.03961.x
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVES:To examine the combined influence of alcohol use and comorbidity on 20-year mortality in older adults (average age 66 at the time of the baseline survey). DESIGN:Longitudinal analysis of a national probability sample-based cohort study. SETTING:Data sources were the National Health and Nutrition Examinatio...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2006.00728.x
更新日期:2006-05-01 00:00:00
abstract::The effect of do-not-resuscitate (DNR) orders on physicians' decisions to provide life-prolonging treatments other than cardiopulmonary resuscitation (CPR) for patients near the end of life was explored using a cross-sectional mailed survey. Each survey presented three patient scenarios followed by 10 treatment decisi...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1532-5415.2002.50620.x
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVES:To estimate the independent effect of hospitalization for ischemic stroke on change in functional status, subsequent hospitalization, and mortality. DESIGN:Secondary analysis of the nationally representative Longitudinal Study on Aging. Baseline (1984) interview data were linked to Medicare hospitalization ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1998.tb01073.x
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVES:To determine whether severe obesity in older people is independently associated with diminished lower extremity physical performance (LEP) in a random sample of homebound older adults that were considered ambulatory. DESIGN:Prospective cohort with 1 year of follow-up (2000-02). SETTING:In-home assessments ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2006.00842.x
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVES:To test the utility of a memory-encoding strategy for improving prospective memory (PM), the ability to remember to execute future goals (e.g., remembering to take medications), which plays an important role in independent living in healthy older adults and those with very mild Alzheimer's disease (AD). DES...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/jgs.14134
更新日期:2016-06-01 00:00:00
abstract::There is accumulating evidence that interactions between beta-amyloid and copper, iron, and zinc are associated with the pathophysiology of Alzheimer's disease (AD). A significant dyshomeostasis of copper, iron, and zinc has been detected, and the mismanagement of these metals induces beta-amyloid precipitation and ne...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1046/j.1532-5415.2003.51368.x
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:To determine the effects of prompted voiding on fecal continence in nursing home residents. DESIGN:Prospective, uncontrolled trial of prompted voiding for urinary incontinence. PARTICIPANTS:One hundred sixty-five nursing home residents who completed a 9 to 10-week trial. MEASUREMENTS:Trained research aides...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章
doi:10.1111/j.1532-5415.1996.tb06415.x
更新日期:1996-04-01 00:00:00
abstract:OBJECTIVES:To understand characteristics of older at-risk drinkers and reasons why they decide to change or maintain their alcohol consumption. DESIGN:Secondary analysis of data from a randomized controlled trial to reduce drinking in at-risk drinkers. SETTING:Three primary care sites in southern California. PARTICI...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/jgs.12394
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:To describe the medical decisions confronting healthcare proxies (HCPs) of nursing home (NH) residents with advanced dementia and to identify factors associated with greater decision-making satisfaction. DESIGN:Prospective cohort study. SETTING:Twenty-two Boston-area NHs. PARTICIPANTS:Three hundred twenty...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2009.02304.x
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVES:To determine to what extent demographic, social support, socioeconomic, geographic, medical, and End-of-Life (EOL) planning factors explain racial and ethnic variation in Medicare spending during the last 6 months of life. DESIGN:Retrospective cohort study. SETTING:Health and Retirement Study (HRS). PARTI...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.14263
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVES:To evaluate survival and causes of death in subjects with idiopathic senile gait disorders. DESIGN:A population-based longitudinal study. SETTING:Survival analysis of the oldest old within the Leiden 85-plus Study. PARTICIPANTS:We distinguished three different groups according to their gait: subjects with...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2000.tb04786.x
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:To identify age-related differences in the treatment of patients with acute myocardial infarction. DESIGN:Retrospective cohort study. SETTING:Two university-affiliated medical centers with integrated clinical programs. PATIENTS:329 patients admitted with acute myocardial infarction in 1988-1990 for whom co...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1532-5415.1994.tb06553.x
更新日期:1994-08-01 00:00:00
abstract::The Acute Care for Elders (ACE) model of care is a multicomponent intervention that improves outcomes for older patients hospitalized for acute medical illnesses. Likewise, stroke units improve outcomes for patients with acute stroke, yet the descriptions of their structure and approach to stroke management are hetero...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1046/j.1532-5415.2003.51521.x
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVES:To provide descriptive epidemiological information on identified depression in nursing home residents. DESIGN:Survey of the 1996 Medical Expenditure Panel Survey-Nursing Home Component (MEPS-NHC). SETTING:Nine hundred fifty-one nursing facilities. PARTICIPANTS:Three thousand seven hundred ten noncomatose ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2003.51458.x
更新日期:2003-10-01 00:00:00
abstract::Investigations of the natural history of blood pressure have generally evaluated mean systolic and diastolic pressure changes. While information, this information is not directly applicable to clinical practice settings, in which patients are usually classified as normotensive or hypertensive. We measured the actual i...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1989.tb02267.x
更新日期:1989-09-01 00:00:00
abstract:OBJECTIVES:To identify factors associated with functional change in an older population and investigate interactions among selected potential risk factors. DESIGN:A population-based prospective cohort study. SETTING:A random sample was selected from the Group Health Cooperative members in the Seattle area from 1994 t...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1532-5415.2002.50408.x
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVES:To understand the potential roles of various patient and provider factors in the underuse of pneumococcal vaccination in Medicare-eligible older African Americans. DESIGN:The Cardiovascular Health Study. SETTING:Four U.S. states. PARTICIPANTS:Seven hundred ninety-five pairs of community-dwelling Medicare-...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1532-5415.2010.03181.x
更新日期:2010-12-01 00:00:00
abstract::Falls are a leading cause of fatal and nonfatal injuries among the elderly in the United States. Despite the importance of fall injuries, epidemiological studies of falls among the elderly have identified neither their causes nor the methods to prevent them. Therefore, we established a community-based surveillance sys...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1988.tb04371.x
更新日期:1988-11-01 00:00:00
abstract:OBJECTIVES:To examine prevalence and resident- and site-level factors associated with potential underuse, overuse, and inappropriate use of antidepressants in older Veterans Affairs (VA) Community Living Center (CLC) residents. DESIGN:Longitudinal study. SETTING:One hundred thirty-three VA CLCs. PARTICIPANTS:Three t...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03522.x
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVES:To examine relationships between race and psychotropic drug use (antidepressant, antianxiety, sedative/hypnotic agents) in informal caregivers with symptoms of depression who provide care for elderly relatives with progressive dementia. Whether racial differences in medication use relate to racial difference...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2005.53155.x
更新日期:2005-03-01 00:00:00
abstract::The literature has identified significant successes in cardiac resuscitation with the use of automated external defibrillators (AEDs) in public areas. As of September 2004, the Food and Drug Administration has authorized the purchase of these devices by the general public without a prescription. For the practicing ger...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.2005.00569.x
更新日期:2006-01-01 00:00:00