Abstract：
OBJECTIVES:To evaluate survival and causes of death in subjects with idiopathic senile gait disorders. DESIGN:A population-based longitudinal study. SETTING:Survival analysis of the oldest old within the Leiden 85-plus Study. PARTICIPANTS:We distinguished three different groups according to their gait: subjects with a normal gait (n = 25), subjects with senile gait disorders (n = 14), and subjects with gait disorders due to known disease (n = 87). The mean age was 90 years in all groups (range 87 to 97 years). MEASUREMENTS:The risk of all cause mortality and cardiovascular mortality was estimated over 5 years of follow-up in a Cox-proportional hazards model, adjusted for age and sex. RESULTS:Eighty-nine of 126 subjects died during follow-up. Mean survival differed among the three groups (P log-rank = .01). All cause mortality risk was increased in subjects with senile gait disorders compared with subjects with a normal gait (RR = 2.8; 95% CI, 1.1-7.3, P = .03) and was similar to subjects with gait disorders caused by known disease (RR = 1.2; 95% CI: .6-2.5, P = .6). Mortality caused by cardiovascular disease also differed among the three groups (P log-rank = .03). The risk of cardiovascular death in subjects with senile gait disorders was twofold greater than in subjects with a normal gait (RR = 2.1; 95% CI, 0.4-10.3). CONCLUSIONS:Senile gait disorders are related to subclinical, perhaps cardiovascular, disease. Senile gait disorders should not be accepted as an inevitable, benign concomitant of the normal aging process.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Bloem BR,Gussekloo J,Lagaay AM,Remarque EJ,Haan J,Westendorp RGdoi
10.1111/j.1532-5415.2000.tb04786.xsubject
Has Abstractpub_date
2000-09-01 00:00:00pages
1098-101issue
9eissn
0002-8614issn
1532-5415journal_volume
48pub_type
杂志文章abstract：OBJECTIVES:Use of objectively measured physical activity (PA) in older adults to assess relationship between PA and risk of all-causes mortality is scarce. This study evaluated the associations of PA based on accelerometry and a questionnaire with the risk of mortality among older adults from a city in Southern Brazil....
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.16180
更新日期：2020-01-01 00:00:00
abstract：:The field has progressed to the point where a genetic investigation of the aging processes in Drosophila can be viewed as constituting both a serious and a feasible research program. There now exists at least one single gene mutant which yields an accelerated aging phenotype, at least two single gene null mutants affe...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.1989.tb02240.x
更新日期：1989-08-01 00:00:00
abstract：OBJECTIVE:To determine predictors of 2-year post-hospitalization mortality in a cohort of elderly hospitalized patients originally assembled to assess the impact of a Geriatric Consultation Team (GCT). DESIGN:Two-year follow-up of an inception cohort. SETTING:University-affiliated tertiary care VA Medical Center. PA...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1992.tb03648.x
更新日期：1992-12-01 00:00:00
abstract：OBJECTIVES:To determine the association between multiple chronic conditions and risk of incident mild cognitive impairment (MCI) and dementia. DESIGN:Prospective cohort study. SETTING:Olmsted County, Minnesota. PARTICIPANTS:Cognitively normal individuals (N = 2,176) enrolled in the Mayo Clinic Study of Aging (MCSA)....
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.13612
更新日期：2015-09-01 00:00:00
abstract：:The aim of this study was to evaluate the usefulness of Silver's Cerebral Function Test in predicting the management and placement of patients admitted to a psychogeriatric hospital. Overall, 205 consecutively admitted patients and 54 age-matched controls living in the community were examined, thereby greatly extendin...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1977.tb00409.x
更新日期：1977-06-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:To optimize health and well-being for all older people, we must collectively develop leaders to pioneer models of care, educate the healthcare workforce, advance research, and engage the community. METHODS:The Emerging Leaders in Aging (ELIA) program was created to train a multiprofessional cadre...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15702
更新日期：2019-03-01 00:00:00
abstract：:From this discussion, several conclusions can be drawn. First, with advancing age there is a decrease in cardiovascular responsiveness and, more specifically, there is a decrease in catecholamine-stimulated chronotropic and inotropic responses. This decreased function has its biochemical correlate in the observation t...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.1985.tb04890.x
更新日期：1985-03-01 00:00:00
abstract：OBJECTIVES:To explore changes in care goals and treatment orders around the occurrence of pneumonia and intake problems, and whether hospitalization is in line with earlier agreed-upon do-not-hospitalize orders. DESIGN:Data were collected as part of the Dutch End of Life in Dementia study (2007-2011), a longitudinal o...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.14667
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVES:To describe the prevalence of diabetes mellitus (DM) in centenarians. DESIGN:Cross-sectional, population-based. SETTING:Forty-four counties in northern Georgia. PARTICIPANTS:Two hundred forty-four centenarians (aged 98-108, 15.8% male, 20.5% African American, 38.0% community dwelling) from the Georgia Cen...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2011.03836.x
更新日期：2012-03-01 00:00:00
abstract：OBJECTIVE:To determine the association between kyphosis (degree of forward curvature of the thoracic spine) and measures of spinal osteoporosis (height loss and vertebral fractures) and chronic back pain and disability in older women. DESIGN:A cross-sectional study. SETTING:Eleven clinical centers in the United State...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1997.tb01470.x
更新日期：1997-06-01 00:00:00
abstract：:Serial creatinine clearances (5 to 14 studies) were obtained for 446 normal volunteers in the Baltimore Longitudinal Study of Aging followed between 1958 and 1981. When those subjects with possible renal or urinary tract disease and subjects on diuretics and antihypertensives were removed from the study, leaving a gro...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1985.tb07117.x
更新日期：1985-04-01 00:00:00
abstract：:Differing concepts of aging, i.e., a normative versus a pathologic process, are presented in historical perspective and are traced through selected writings from ancient China, India, Egypt, and Greece into more modern times. These is no consistent shift across epochs from one to the other perspective, and mixed persp...
journal_title：Journal of the American Geriatrics Society
pub_type： 历史文章,杂志文章
doi：10.1111/j.1532-5415.1982.tb07104.x
更新日期：1982-04-01 00:00:00
abstract：:The reported prevalence of depressive symptomatology among the elderly ranges from 5 to 65 percent in hospital and community populations. Depression is considered the most common emotional disorder of advanced age. One of the chief diagnostic problems has been the lack of differentiation between disorders manifested b...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1980.tb00205.x
更新日期：1980-02-01 00:00:00
abstract：OBJECTIVES:To examine recent trends in discharge disposition after hospitalization for hip fracture. DESIGN:Retrospective observational study using data from the 5% random sample of Medicare claims data from 2001 to 2005 that the Centers for Medicare and Medicaid Services makes available for research purposes. SETTIN...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2008.01688.x
更新日期：2008-06-01 00:00:00
abstract：OBJECTIVES:To determine whether body mass index (BMI) is independently associated with cognitive function in postmenopausal women and the relationship between body fat distribution as estimated by waist-hip ratio (WHR). DESIGN:Cross-sectional data analysis. SETTING:Baseline data from the Women's Health Initiative (WH...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2010.02969.x
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVES:To analyze experience of endoscopic retrograde cholangiopancreatography (ERCP) in patients with of different age cohorts and discuss the risk factors of early mortality after ERCP. DESIGN:Retrospective study. SETTING:Tertiary care medical center. PARTICIPANTS:Two hundred sixty-four patients with pancreato...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2009.02477.x
更新日期：2009-10-01 00:00:00
abstract：OBJECTIVES:To determine whether offspring of centenarians acquired protection from age-related diseases. DESIGN:Case-control study. SETTING:The study was part of the Longevity Genes Project at Albert Einstein College of Medicine. PARTICIPANTS:Centenarians (n=145), offspring of centenarians (n=180), and spouses of th...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2004.52068.x
更新日期：2004-02-01 00:00:00
abstract：OBJECTIVES:To review the epidemiology, pathophysiology, and etiology of congestive heart failure (CHF) in older adults. METHODS:Published reports relevant to the epidemiology, pathophysiology, and etiology of CHF were systematically reviewed. Studies involving older adults and more recent studies were emphasized. RES...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.1997.tb02968.x
更新日期：1997-08-01 00:00:00
abstract：OBJECTIVE:The Health Care Surrogate Act (HCSA) in Illinois has been proposed as a model for state laws naming surrogate medical decision-makers for those without advance directives (ADs). Our objective was to determine if the HCSA identifies the same surrogate as older persons would choose for themselves. If not, is th...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1996.tb02437.x
更新日期：1996-02-01 00:00:00
abstract：OBJECTIVES:Older black patients are at risk for underutilization of preventive services. Our objectives were to assess the delivery of five preventive services in Title 330-funded health centers in low income neighborhoods in Cleveland, Ohio, and to determine the association of health system factors and health status w...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2000.tb03902.x
更新日期：2000-02-01 00:00:00
abstract：:One hundred seventy-one patients, 60 years of age or older with isolated systolic hypertension, were randomly assigned to receive chlorthalidone 12.5, 25.0, or 50.0 mg or placebo once daily for 12 weeks. The majority of the patients receiving chlorthalidone 12.5 mg achieved therapeutic success with no clinically signi...
journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1532-5415.1986.tb04203.x
更新日期：1986-03-01 00:00:00
abstract：OBJECTIVES:To evaluate national trends in electrocardiogram (EKG) monitoring in Veterans Affairs (VA) beneficiaries prescribed high-dose citalopram before and after the 2011-12 Food and Drug Administration (FDA) safety warnings. DESIGN:Interrupted time-series analyses. SETTING:National VA healthcare system data linke...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15420
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVES:To determine the effect of new oral anticoagulants (NOACs) on prescribing practices in older adults with atrial fibrillation (AF). DESIGN:Retrospective observational cohort study. SETTING:Academic medical center in St. Louis, Missouri. PARTICIPANTS:Individuals aged 75 and older with AF admitted to the hos...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15058
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVES:To examine the effects of dehydroepiandrosterone (DHEA) supplementation on cognitive function and quality of life in healthy older adults. DESIGN:Double-blind, randomized, controlled clinical trial. SETTING:Clinical research facility. PARTICIPANTS:One hundred ten men and 115 women aged 55 to 85 (mean +/- ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1532-5415.2008.01768.x
更新日期：2008-07-01 00:00:00
abstract：:The authors compared the demographic and clinical characteristics and treatment recommendations for elderly (greater than or equal to 60 years) and younger patients (17 to 59 years) seen for an emergency psychiatric consultation in a teaching general hospital. Findings revealed 11 distinctive characteristics that diff...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1986.tb05474.x
更新日期：1986-02-01 00:00:00
abstract：OBJECTIVES:To develop and validate a comprehensive quality assessment tool for emergency department (ED) geriatric care. DESIGN:Four-step study: (1) Content development of tool by a multidisciplinary panel, (2) survey of ED lead physicians and nurses, (3) development of subscales using principal component analysis and...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15137
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVES:To investigate whether proton pump inhibitor (PPI) therapy reduces the frequency of common colds and exacerbations in patients with chronic obstructive pulmonary disease (COPD). DESIGN:Twelve-month, randomized, observer-blind, controlled trial. SETTING:A university hospital and three city hospitals in Miya...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/j.1532-5415.2009.02349.x
更新日期：2009-08-01 00:00:00
abstract：:The hypochondriacal attitudes of 53 aged community residents were studied. No significant correlations were found with situational stress, sex, or ethnicity (English-speaking vs Spanish-speaking). The levels of hypochondriasis appeared to be inversely related to self-evaluation of memory ability. There was no indicati...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1981.tb02392.x
更新日期：1981-01-01 00:00:00
abstract：:The contribution of frailty to human morbidity and mortality is immense. Yet it lacks a conceptual framework. By borrowing from the hypotheses provided by the thermophysicists, frailty can be understood in a way that both interrelates the relationship between form and function and provides medical science with an oper...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：
更新日期：1993-09-01 00:00:00
abstract：:An operational definition of frailty is important for clinical care, research, and policy planning. The literature on the clinical definitions, screening tools, and severity measures of frailty were systematically reviewed as part of the Canadian Initiative on Frailty and Aging. Searches of MEDLINE from 1997 to 2009 w...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.2011.03597.x
更新日期：2011-11-01 00:00:00
