Abstract:
BACKGROUND:C-Reactive protein (CRP) has been shown to be a strong predictor of coronary heart disease (CHD) and is being considered in cardiovascular disease risk assessment. The number of normolipidemic individuals who are eligible for evaluation of CRP in overall CHD risk assessment is not known. METHODS:We analyzed data from the National Health and Nutrition Examination Survey 1999-2000 and computed the prevalence of high CRP (>3 mg/L) among normolipidemic adults. We also computed the prevalence among individuals free of CHD and diabetes. In addition, we examined the prevalence stratified by body mass index. RESULTS:The prevalence of high CRP among those with lipid concentrations within recommended values ranged from 28.8% to 35.3%, depending on the lipid fraction examined. Exclusion of individuals with CHD or diabetes and those with CRP concentrations >10 mg/L reduced the prevalence range (23.1-27.1%). Prevalence increased with increasing body mass index. CONCLUSIONS:In 2000, approximately 12 million adults in the United States considered normolipidemic had high CRP concentrations. Additional studies to explore the role of CRP in cardiovascular disease risk assessment are needed.
journal_name
Clin Chemjournal_title
Clinical chemistryauthors
Ajani UA,Ford ES,Mokdad AHdoi
10.1373/clinchem.2004.036004subject
Has Abstractpub_date
2004-09-01 00:00:00pages
1618-22issue
9eissn
0009-9147issn
1530-8561pii
clinchem.2004.036004journal_volume
50pub_type
杂志文章abstract:BACKGROUND:The analytical and clinical performance of homogeneous LDL-cholesterol assays has been reported, but their reactions with subfractions of LDL and VLDL have not been described in detail. METHODS:We evaluated reaction selectivity of two homogeneous LDL-cholesterol assays, LDLk (Kyowa Medex) and LDLd (Daiichi ...
journal_title:Clinical chemistry
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journal_title:Clinical chemistry
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journal_title:Clinical chemistry
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journal_title:Clinical chemistry
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journal_title:Clinical chemistry
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doi:
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doi:
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journal_title:Clinical chemistry
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doi:
更新日期:1975-01-01 00:00:00
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doi:
更新日期:1975-06-01 00:00:00
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doi:
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doi:
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journal_title:Clinical chemistry
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doi:
更新日期:1979-07-01 00:00:00
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journal_title:Clinical chemistry
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doi:
更新日期:1985-07-01 00:00:00
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journal_title:Clinical chemistry
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doi:
更新日期:1976-09-01 00:00:00
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