Abstract:
:A gel including aescin, essential phospholipids (EPL), and heparin (EG) has been used for many years for local treatment of venous, microcirculatory alterations (varicose veins, chronic venous insufficiency). Bruises, swelling, thrombophlebitis, and contusions are effectively treated with this compound. The aim of this study was the evaluation of the efficacy of the effects of an AEPL (aescin+EPL) gel on the microcirculation in subjects with chronic venous insufficiency, venous hypertension (CVH), and venous microangiopathy. Transcutaneous PO(2) was measured at the perimalleolar region. After 2 weeks of treatment, all individual values (100%) were significantly increased (p < 0.05). In all patients, PO(2) increased, indicating a decrease in level of venous microangiopathy. Considering transcutaneous skin PO(2), treatment with AEPL in areas of venous microangiopathy is beneficial in the prevention of ulceration and improves skin healing.
journal_name
Angiologyjournal_title
Angiologyauthors
Cesarone MR,Belcaro G,Ippolito E,Ricci A,Ruffini M,Dugall Mdoi
10.1177/000331970405500602subject
Has Abstractpub_date
2004-05-01 00:00:00pages
S7-10eissn
0003-3197issn
1940-1574journal_volume
55 Suppl 1pub_type
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