Abstract:
:Chronic musculoskeletal diseases such as arthritis, malignancy, chronic injury/ inflammation, and chronic musculoskeletal pain often pose challenges for current clinical imaging modalities. There is hope that a growing field, referred to as "molecular imaging," will shed new light on these chronic phenomenon as it aims to noninvasively detect special molecular and physiologic effects such as metabolism rate, specific proteins, cell death, and particular gene-related events. Molecular imaging represents recent advances in imaging technology, engineering, chemistry, molecular biology, and genetics that have coalesced into a multidisciplinary and multimodality effort. Molecular probes are currently being developed not only in radionuclide-based techniques but also in magnetic resonance imaging, magnetic resonance spectroscopy, ultrasound, and the emerging field of optical imaging. Furthermore, molecular imagers are fueling the development of novel molecular therapies and gene therapy, as tracking these efforts in living subjects is now possible with molecular imaging protocols.
journal_name
Semin Musculoskelet Radioljournal_title
Seminars in musculoskeletal radiologyauthors
Biswal Sdoi
10.1055/s-2004-815679subject
Has Abstractpub_date
2003-12-01 00:00:00pages
317-50issue
4eissn
1089-7860issn
1098-898Xjournal_volume
7pub_type
杂志文章,评审abstract::This article reviews the basics of image-guided intervention of musculoskeletal neoplasms. Image-guided procedures are playing an ever-increasing role in the diagnosis, staging, and treatment of musculoskeletal tumors. The successful handling of these lesions necessitates a multidisciplinary approach, with the radiolo...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0033-1343096
更新日期:2013-04-01 00:00:00
abstract::In rheumatoid arthritis (RA), due to its superior contrast resolution and tomographic nature, magnetic resonance (MR) imaging can depict soft tissue and joint involvement better than plain radiography. Active synovitis and pannus are shown by a wide variety of contrast on T1- and T2-weighted images. They are markedly ...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-2001-15674
更新日期:2001-06-01 00:00:00
abstract::Disorders of ligaments and tendons at the midfoot are less common than those around the ankle and at the hindfoot. Nevertheless, disorders of the distal portions of the anterior and posterior tibialis tendons (ATT and PTT) and the spring ligament complex have an important clinical impact and can be treated with surger...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2005-921939
更新日期:2005-09-01 00:00:00
abstract::Fractures are common in children with some requiring surgical reduction and fixation to maintain anatomical alignment. Although various surgical techniques and principles are shared between children and adults, certain unique considerations in children can influence the surgical approach and device selection. In parti...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0037-1609013
更新日期:2018-02-01 00:00:00
abstract::Body composition entails the measurement of muscle and fat mass in the body and has been shown to impact clinical outcomes in various aspects of human health. As a result, the need is growing for reliable and efficient noninvasive tools to measure body composition. Traditional methods of estimating body composition, a...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0039-3400267
更新日期:2020-02-01 00:00:00
abstract::The triangular fibrocartilage complex (TFCC) is a crucial structure for both maintaining the stability of the distal radioulnar joint (DRUJ) and acting as a cushion for axial loading of the ulnocarpal joint. Injury to the TFCC can lead to early degeneration of the DRUJ and ulnocarpal joint, with resultant chronic wris...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0039-1688715
更新日期:2019-08-01 00:00:00
abstract::Benign bone cysts (aneurysmal and unicameral) often require treatment to prevent pathological fractures. Percutaneous injections are less invasive than surgery. We describe the different percutaneous treatments available: local injection of steroids, calcitonin, or bone marrow in unicameral bone cysts, and Ethibloc(R)...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-2008-1080152
更新日期:1997-01-01 00:00:00
abstract::For the evaluation of soft tissue masses, sonography (US) has proved to be very accurate in confirming the presence or absence of a lesion, with a very high negative predictive value. Many soft tissue masses result from trauma, inflammation, infection, or cystic changes and are not true neoplasms. In the proper clinic...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-2008-1080056
更新日期:1999-01-01 00:00:00
abstract::Computed tomography (CT) is a modality of choice for the study of the musculoskeletal system for various indications including the study of bone, calcifications, internal derangements of joints (with CT arthrography), as well as periprosthetic complications. However, CT remains intrinsically limited by the fact that i...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0035-1569254
更新日期:2015-12-01 00:00:00
abstract::Magnetic resonance (MR) imaging technique and findings in the setting of athletic pubalgia, including injury at the rectus abdominis/adductor aponeurosis, are becoming widely recognized. A subset of these patients is treated with various pelvic floor repairs, mesh reinforcements, and tendon releases. Most of these pat...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0031-1286017
更新日期:2011-09-01 00:00:00
abstract::Awareness of risk factors associated with impending fracture and its radiologic appearance allows early diagnosis, supports prophylactic surgical treatment, and prevents the multiple complications of a pathologic fracture. Because the femur is the most common long bone affected by metastatic bone lesions, we address t...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0038-1675804
更新日期:2019-02-01 00:00:00
abstract::This history page in the series "Leaders in MSK radiology" is dedicated to the memory and achievements of the Norwegian physician Christian Magnus Falsen Sinding-Larsen who's name is connected to the medical eponym Sinding-Larsen-Johansson disease. ...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-0040-1701497
更新日期:2020-06-01 00:00:00
abstract::Foot pain and disability may curtail the performance of simple routine tasks, work-related duties, and athletic activities. Disorders of the plantar fascia are commonly encountered in the diagnostic evaluation of subcalcaneal heel pain. The approach to imaging the ankle and foot has undergone significant amendment wit...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-2002-32357
更新日期:2002-06-01 00:00:00
abstract::Bisphosphonates have been widely used in the treatment of osteoporosis with well-documented long-term efficacy and safety, particularly in postmenopausal patients. But over the past decade, low-energy atypical subtrochanteric and proximal diaphyseal femoral fractures have emerged as an unexpected complication of prolo...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0036-1593766
更新日期:2016-09-01 00:00:00
abstract::In recent years significant advances have been made in imaging techniques. Dual-energy computed tomography has revolutionized the ability to detect and quantify gout. The key ultrasound features of gout have been defined. Magnetic resonance imaging is an excellent modality for demonstrating the extent and severity of ...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0038-1639484
更新日期:2018-04-01 00:00:00
abstract::31Phosphorus (31P) magnetic resonance spectroscopy (MRS) is well suited for gathering data on skeletal muscle energetics in vivo. The technique has evolved to the point where it has become an important tool in the study of the pathophysiology both of rare primary disorders of muscle such as the mitochondrial myopathie...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2000-13172
更新日期:2000-01-01 00:00:00
abstract::There is a broad spectrum of benign soft tissue tumors in children, including, among others, vascular, fibroblastic/myofibroblastic, and adipocytic lesions as well as pseudotumors. The diagnosis of superficial soft tissue tumors is in many instances made clinically, whereas those with more equivocal presentation and t...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0029-1237689
更新日期:2009-09-01 00:00:00
abstract::The vast majority of soft tissue masses are benign. Benign lesions such as superficial lipomas and ganglia are by far the most common soft tissue masses and can be readily identified and excluded on ultrasound (US). US is an ideal triaging tool for superficial soft tissue masses. Compared with magnetic resonance imagi...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-0039-3402060
更新日期:2020-04-01 00:00:00
abstract::Congenital upper limb malformations represent complex pathologies because of their varied clinical presentations, imaging features, and etiologies. They can be divided into (1) failure of formation with transverse, intercalary, and longitudinal (preaxial, postaxial, and mesoaxial) deficiencies, (2) failure of differen...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0032-1311766
更新日期:2012-04-01 00:00:00
abstract::Fortunately, serious injuries to the cervical spine in athletes are rare. Most injuries are self-limited and related to sprains and strains. Although radiographs may be used to screen for fractures, potentially serious soft-tissue injuries require additional diagnostic techniques. In these cases, advanced imaging with...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2004-823017
更新日期:2004-03-01 00:00:00
abstract::Musculoskeletal (MSK) radiology plays a crucial role in the diagnosis and management of MSK disorders and has rapidly expanded in tandem with advances in technology and improved access to imaging. Although anatomical imaging remains the mainstay of MSK radiology, significant progress has been made in functional and mo...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-0038-1673623
更新日期:2018-11-01 00:00:00
abstract::Early diagnosis, followed by early initiation and optimal adjustments of aggressive therapies, are acknowledged as essential to optimize long-term clinical and radiological outcome in rheumatoid arthritis (RA). This requires sensitive methods for detection and monitoring of the primary feature of RA--the synovitis. In...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2004-861576
更新日期:2004-12-01 00:00:00
abstract::Tuberculosis (TB) is no longer a disease limited to developing nations and is still a major cause of significant morbidity and mortality worldwide. The indolent clinical presentation, emergence of multidrug-resistant mycobacteria, and association with human immunodeficiency virus infection poses obstacles for early di...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0031-1293491
更新日期:2011-11-01 00:00:00
abstract::Over the last 2 decades, the definition of pathomechanical concepts that link osseous deformities to chondrolabral damage and expose young and active patients to the risk of early osteoarthritis has led to a tremendous increase in the number of joint-preserving surgeries performed. The rise in arthroscopic procedures ...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0039-1678729
更新日期:2019-06-01 00:00:00
abstract::Ultrasound (US) and MR imaging have been shown able to detect in-depth features of brachial plexus anatomy and to localize pathological lesions in disorders where electrophysiology and physical findings are nonspecific or nonlocalizing. High-end gradient technology, phased array coils, and selection of an appropriate ...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0030-1268072
更新日期:2010-11-01 00:00:00
abstract::A potential treatment for chronic tendinosis or tendinopathy is percutaneous ultrasound-guided tendon fenestration, also termed dry needling or tenotomy. This procedure involves gently passing a needle through the abnormal tendon multiple times to change a chronic degenerative process into an acute condition that is m...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0033-1333942
更新日期:2013-02-01 00:00:00
abstract::Osteoarthritis (OA) is the most common joint disease in the United States. The prevalence of OA is rising due to an aging population and increasing rates of obesity. Magnetic resonance imaging (MRI) allows an incomparable noninvasive assessment of all joint structures. Irreversible and progressive degradation of the a...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0039-1695720
更新日期:2019-10-01 00:00:00
abstract::Ultrasound is a nonionizing, low-cost, portable imaging technique for the evaluation of tendons, muscles, joints, soft tissue masses, and cysts, especially in patients unable to tolerate computed tomography or magnetic resonance imaging. These advantages make ultrasound an ideal modality for guiding musculoskeletal in...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-1001883
更新日期:2007-06-01 00:00:00
abstract::Shoulder ultrasound is a commonly performed imaging study that can accurately determine the presence of rotator cuff tendinosis and tears, as well as subacromial-subdeltoid bursal and long head of biceps tendon pathology. High accuracy depends on an awareness of imaging pitfalls that can be encountered and lead to ove...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0039-1693488
更新日期:2019-08-01 00:00:00
abstract::Synovial membranes line the diarthrodial (movable) joints, bursae, and tendon sheaths of the body. The primary function of this specialized, vascular tissue is to serve as a filter system that lubricates and nourishes the articular structures as well as serving as a shock-absorber. The synovium is affected by a variet...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0029-1242186
更新日期:2009-12-01 00:00:00