Gestational surrogacy.

abstract：:In the male genital tract, reactive oxygen species (ROS) are generated by spermatozoa and leukocytes including neutrophils and macrophages. ROS are involved in the regulation of sperm functions such as capacitation and the acrosome reaction. Infections lead to an excessive ROS production, resulting in an 'oxidative bu...

journal_title：Human reproduction update

authors： Ochsendorf FR

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Androgens, FSH, anti-Müllerian hormone (AMH) and estradiol (E2) are essential in human ovarian folliculogenesis. However, the interactions between these four players is not fully understood. OBJECTIVES AND RATIONALE:The purpose of this review is to highlight the chronological sequence of the appearance and ...

journal_title：Human reproduction update

authors： Dewailly D,Robin G,Peigne M,Decanter C,Pigny P,Catteau-Jonard S

更新日期：2016-11-01 00:00:00

abstract：UNLABELLED:BACKGROUND; Combined oral contraceptives (COCs) reduce levels of androgen, especially testosterone (T), by inhibiting ovarian and adrenal androgen synthesis and by increasing levels of sex hormone-binding globulin (SHBG). Although this suppressive effect has been investigated by numerous studies over many ye...

journal_title：Human reproduction update

authors： Zimmerman Y,Eijkemans MJ,Coelingh Bennink HJ,Blankenstein MA,Fauser BC

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:With the recent development of CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 genome editing technology, the possibility to genetically manipulate the human germline (gametes and embryos) has become a distinct technical possibility. Although many technical challenges still need to be...

journal_title：Human reproduction update

authors： Vassena R,Heindryckx B,Peco R,Pennings G,Raya A,Sermon K,Veiga A

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:First-trimester miscarriage affects up to a quarter of women worldwide. With many competing treatment options available, there is a need for a comprehensive evidence synthesis. OBJECTIVES AND RATIONALE:We conducted a systematic review and network meta-analysis to assess the effectiveness and safety of treat...

journal_title：Human reproduction update

authors： H Al Wattar B,Murugesu N,Tobias A,Zamora J,Khan KS

更新日期：2019-05-01 00:00:00

abstract：:The effects on reproductive tract development in male rats, of neonatal exposure to potent (reference) oestrogens, diethylstilboestrol (DES) and ethinyl oestradiol (EE), with those of two environmental oestrogens, octylphenol and hisphenol A were systematically compared. Other treatments, such as administration of a g...

journal_title：Human reproduction update

authors： Williams K,McKinnell C,Saunders PT,Walker M,Fisher JS,Turner KJ,Atanassova N,Sharpe M

更新日期：2001-05-01 00:00:00

abstract：:At present, the management of non-organ confined prostate cancer, whether it is a recurrence or metastasis, continues to evolve based on prostate cancer detection using prostate-specific antigen and the development of medications as alternatives for the classical orchiectomy, which induced irreversible implications fo...

journal_title：Human reproduction update

authors： d'Ancona FC,Debruyne FM

更新日期：2005-05-01 00:00:00

abstract：:Cryopreservation of testicular tissue might benefit prepubertal boys who must undergo chemotherapy or radiotherapy. Cryopreservation of testicular tissue and testicular cells for intracytoplasmic sperm injection (ICSI) is feasible and widely applied. Testicular tissue from prepubertal boys can also be frozen, by apply...

journal_title：Human reproduction update

authors： Hovatta O

更新日期：2001-07-01 00:00:00

abstract：:During the last decade oocyte donation has been highly successful for treating women previously thought to be hopelessly infertile. The pregnancy rate after oocyte donation is among the highest reported for any fertility-enhancing procedure. Most investigators have noted an increased rate of obstetric complications in...

journal_title：Human reproduction update

authors： Söderström-Anttila V

更新日期：2001-01-01 00:00:00

abstract：:Conservative management of at least part of both the ovary and uterus can be proposed in patients with borderline ovarian tumour, in order to preserve fertility potential. This conservative management could be carried out even in patients with borderline ovarian tumour associated with non-invasive peritoneal implants ...

journal_title：Human reproduction update

authors： Morice P,Camatte S,Wicart-Poque F,Atallah D,Rouzier R,Pautier P,Pomel C,Lhommé C,Duvillard P,Castaigne D

更新日期：2003-03-01 00:00:00

abstract：:After colonization of the gonad, mouse female germ cells enter into the prophase of the first meiotic division as a mid-gestational hallmark of gender. Perinatally, oocytes interact with granulosa cells to form primordial follicles which, with cyclic periodicity, enter into a 3-week growth phase that culminates in mei...

journal_title：Human reproduction update

authors： Amleh A,Dean J

更新日期：2002-09-01 00:00:00

abstract：:This review presents detailed risk estimates from relevant epidemiological and other studies on the comparative safety of second and third generation oral contraceptives (OC). Written with the intention of presenting a repository of the available information, it also discourses briefly into the symptomatology and diag...

journal_title：Human reproduction update

authors： Edwards RG,Cohen J

更新日期：1999-11-01 00:00:00

abstract：:Protamines are the major nuclear sperm proteins. The human sperm nucleus contains two types of protamine: protamine 1 (P1) encoded by a single-copy gene and the family of protamine 2 (P2) proteins (P2, P3 and P4), all also encoded by a single gene that is transcribed and translated into a precursor protein. The protam...

journal_title：Human reproduction update

authors： Oliva R

更新日期：2006-07-01 00:00:00

abstract：:Mammalian oocytes begin meiosis in the fetal ovary, but only complete it when fertilized in the adult reproductive tract. This review examines the cell biology of this protracted process: from entry of primordial germ cells into meiosis to conception. The defining feature of meiosis is two consecutive cell divisions (...

journal_title：Human reproduction update

authors： Jones KT

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The aim of this meta-analysis was to investigate whether any difference exists in success rate of clinical outcomes of assisted reproductive technologies (ART) between women who actively smoke cigarettes at the time of treatment and those who do not. METHODS:An intensive computerized search was conducted on...

journal_title：Human reproduction update

authors： Waylen AL,Metwally M,Jones GL,Wilkinson AJ,Ledger WL

更新日期：2009-01-01 00:00:00

abstract：:The human ovary is a dynamic organ which continually changes in size and activity through life, as an integral part of the changes that the female is going through before during and after her reproductive life. Following the rapid increase in the use of transvaginal scan in recent years, the measurement of ovarian vol...

journal_title：Human reproduction update

authors： Lass A,Brinsden P

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:The use of nuclear transfer (NT) has been proposed as a novel reproductive treatment to overcome the transmission of maternally-inherited mitochondrial DNA (mtDNA) mutations. Pathogenic mutations in mtDNA can cause a wide-spectrum of life-limiting disorders, collectively known as mtDNA disease, for which the...

journal_title：Human reproduction update

authors： Craven L,Tang MX,Gorman GS,De Sutter P,Heindryckx B

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:More than 15 million women, many of reproductive age, were infected with human immunodeficiency virus (HIV) at the end of 2007. As the HIV epidemic evolves, heterosexual intercourse is increasingly risky: the risk of infection in exposed young women is 4- to 7-fold higher than in young men and nearly half a ...

journal_title：Human reproduction update

authors： Heikinheimo O,Lähteenmäki P

更新日期：2009-03-01 00:00:00

abstract：:The signals and mechanisms that synchronize the timing of human parturition remain a mystery and a better understanding of these processes is essential to avert adverse pregnancy outcomes. Although our insights into human labor initiation have been informed by studies in animal models, the timing of parturition relati...

journal_title：Human reproduction update

authors： Menon R,Bonney EA,Condon J,Mesiano S,Taylor RN

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Mild ovarian stimulation has emerged as an alternative to conventional IVF with the advantages of being more patient-friendly and less expensive. Inadequate data on pregnancy outcomes and concerns about the cycle cancellation rate (CCR) have prevented mild, or low-dose, IVF from gaining wide acceptance. OBJ...

journal_title：Human reproduction update

authors： Datta AK,Maheshwari A,Felix N,Campbell S,Nargund G

更新日期：2020-11-04 00:00:00

abstract：:Great progress had been achieved during the last 20 years in the field of ovulation induction in patients with polycystic ovary syndrome (PCOS). Clomiphene citrate remains the first line of treatment for all anovulatory women with PCOS, since in properly selected patients the cumulative pregnancy rate approaches that ...

journal_title：Human reproduction update

authors： Messinis IE,Milingos SD

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Induced abortion is a common procedure. However, there is marked variation in accessibility of services across England. Accessing abortion services may be difficult, particularly for women who live in remote areas, are in the second trimester of pregnancy, have complex pre-existing conditions or have difficu...

journal_title：Human reproduction update

authors： O'Shea LE,Hawkins JE,Lord J,Schmidt-Hansen M,Hasler E,Cameron S,Cameron IT

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Every year 30% of individuals above age 65 fall, and falls are the principal cause of bone fractures. To reduce fracture incidence requires both prevention of falls and maintenance of bone strength. METHODS:PubMed searches were performed, for studies of the epidemiology of fractures, bone physiology, endocr...

journal_title：Human reproduction update

authors： ESHRE Capri Workshop Group.

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Activins are members of the pleiotrophic family of the transforming growth factor-beta (TGF-β) superfamily of cytokines, initially isolated for their capacity to induce the release of FSH from pituitary extracts. Subsequent research has demonstrated that activins are involved in multiple biological functions...

journal_title：Human reproduction update

authors： Wijayarathna R,de Kretser DM

更新日期：2016-04-01 00:00:00

abstract：:The long-term clinical effects of ethinyl estradiol and the impact on environmental safety of the alkylated estrogen components used in combined contraceptive pills remain the subject of debate. The development of improved methods for the use of progestogen-only contraception would represent a viable and desirable opt...

journal_title：Human reproduction update

authors： Collins J,Crosignani PG,ESHRE Capri Workshop Group.

更新日期：2003-07-01 00:00:00

abstract：:During the elongating spermatid stage of spermiogenesis, human sperm chromatin undergoes a complex transition in which histones are extensively replaced by protamines in a carefully regulated transition including histone modifications and intermediate and temporary replacement of the histones by sperm-specific transit...

journal_title：Human reproduction update

authors： Carrell DT,Emery BR,Hammoud S

更新日期：2007-05-01 00:00:00

abstract：:The examination of fetal cells, specifically erythroblasts, and cell-free fetal DNA from the blood of pregnant women is currently the subject of intense research with the aim of developing new risk-free methods for prenatal diagnosis. An unexpected finding made during these studies was that the traffic of fetal erythr...

journal_title：Human reproduction update

authors： Hahn S,Holzgreve W

更新日期：2002-11-01 00:00:00

abstract：:The number of cell divisions during embryonic and fetal life makes the embryo/fetus particularly vulnerable to effects resulting from exposure to an adverse intrauterine environment. Exposure to drugs and irradiation at this stage of development are able to cause congenital malformations and various cancers in later l...

journal_title：Human reproduction update

authors： Petry CJ,Hales CN

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Despite great advances in assisted reproductive technology, poor ovarian response (POR) is still considered as one of the most challenging tasks in reproductive medicine. OBJECTIVE AND RATIONALE:The aim of this systemic review is to evaluate the role of different adjuvant treatment strategies on the probabi...

journal_title：Human reproduction update

authors： Zhang Y,Zhang C,Shu J,Guo J,Chang HM,Leung PCK,Sheng JZ,Huang H

更新日期：2020-02-28 00:00:00

abstract：BACKGROUND:Zika virus (ZIKV) is an arthropod-borne virus of the family Flaviviridae, genus Flavivirus. ZIKV is currently the focus of an ongoing pandemic and worldwide public health emergency. Although originally isolated in 1947, its pathogenesis was poorly known and very few documented infections were published until...

journal_title：Human reproduction update

authors： Epelboin S,Dulioust E,Epelboin L,Benachi A,Merlet F,Patrat C

更新日期：2017-11-01 00:00:00