Percutaneous angioscopic evaluation of luminal changes induced by excimer laser angioplasty.

Abstract:

:Angioscopy has been shown to provide more detailed information on lesion morphology before and after interventional procedures than angiography. Therefore to evaluate the effects of laser angioplasty, angioscopy was performed in five patients with peripheral or coronary vascular disease who underwent excimer laser angioplasty. The excimer laser was operated at 308 nm, 135 nsec, 25 Hz, and 40 to 60 mjoules/mm2 and was coupled into multifiber wire-guided catheters of 1.4 to 2.0 mm diameter for coronary lesions and into catheters of 2.2 mm diameter for peripheral lesions. There were three coronary (one left anterior descending, one circumflex, one right coronary artery) and two peripheral (one common iliac artery, one superficial femoral artery) lesions. Angioscopy was successfully performed before and after laser ablation without any complications in all five lesions. The characteristics of angioscopic findings after excimer laser angioplasty consisted of flaps, fractures of plaques, and abundant tissue remnants. There was no apparent thermal injury. Recanalized channels were small and irregular. These results indicate that (1) angioscopy is effective and safe for evaluation of lesion morphology after laser angioplasty; (2) laser ablation does not result in thermal injury; and (3) irregular channels after recanalization and abundant tissue remnants may explain the suboptimal results after laser angioplasty.

journal_name

Am Heart J

journal_title

American heart journal

authors

Nakamura F,Kvasnicka J,Uchida Y,Geschwind HJ

doi

10.1016/0002-8703(92)90058-4

subject

Has Abstract

pub_date

1992-12-01 00:00:00

pages

1467-72

issue

6

eissn

0002-8703

issn

1097-6744

pii

0002-8703(92)90058-4

journal_volume

124

pub_type

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