Diagnostic value of hemosiderin-containing macrophages in bronchoalveolar lavage.

Abstract:

STUDY OBJECTIVE:Our objective was to determine if the hemosiderin content of BAL macrophages allows us to draw any differential diagnostic conclusions in a variety of lung diseases. PATIENTS AND STUDY DESIGN:One hundred one patients who underwent BAL for different diagnostic reasons were studied prospectively. MAIN RESULTS:The highest values for the hemosiderin score (HS) were found in patients with active alveolar hemorrhage and patients who had undergone heart transplantation for congestive heart failure. Compared to a control population, patients with Pneumocystis carinii pneumonia or invasive aspergillosis had a higher HS than patients with bacterial pneumonia or mycobacterial lung infection. High or intermediate values for HS were more often found in patients with a low than in those with a normal platelet count. CONCLUSIONS:The differential diagnostic conclusions which can be based on an HS are limited.

journal_name

Chest

journal_title

Chest

authors

Grebski E,Hess T,Hold G,Speich R,Russi E

doi

10.1378/chest.102.6.1794

subject

Has Abstract

pub_date

1992-12-01 00:00:00

pages

1794-9

issue

6

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)40860-3

journal_volume

102

pub_type

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