Abstract:
STUDY OBJECTIVE:Our objective was to determine if the hemosiderin content of BAL macrophages allows us to draw any differential diagnostic conclusions in a variety of lung diseases. PATIENTS AND STUDY DESIGN:One hundred one patients who underwent BAL for different diagnostic reasons were studied prospectively. MAIN RESULTS:The highest values for the hemosiderin score (HS) were found in patients with active alveolar hemorrhage and patients who had undergone heart transplantation for congestive heart failure. Compared to a control population, patients with Pneumocystis carinii pneumonia or invasive aspergillosis had a higher HS than patients with bacterial pneumonia or mycobacterial lung infection. High or intermediate values for HS were more often found in patients with a low than in those with a normal platelet count. CONCLUSIONS:The differential diagnostic conclusions which can be based on an HS are limited.
journal_name
Chestjournal_title
Chestauthors
Grebski E,Hess T,Hold G,Speich R,Russi Edoi
10.1378/chest.102.6.1794subject
Has Abstractpub_date
1992-12-01 00:00:00pages
1794-9issue
6eissn
0012-3692issn
1931-3543pii
S0012-3692(16)40860-3journal_volume
102pub_type
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