Long-term effects of hormone replacement therapy on Doppler-derived parameters of aortic flow in postmenopausal women.

Abstract:

:Eighteen postmenopausal women were examined by Doppler echocardiography before initiation of HRT (T1), then after ten weeks (T2) and one year (T3). This study group was compared with another in which HRT was not used. Flow velocity integral, which correlates with SV, and MA, an indicator of cardiac contractility, were calculated. In the study group, PFV was 107 +/- 18 cm/s at T1 and increased significantly at T2 and T3. Ejection time, which was prolonged at T2 compared to T1, returned to its basal value at T3. Flow velocity integral increased at T2, but this change was only partially sustained at T3. Mean acceleration maintained its increase throughout T2 to T3. None of the Doppler parameters showed a significant change in the controls from T1 to T3. Our results suggest that the peripheral hemodynamic effects of HRT, such as vasodilatation, are transient, whereas the central effects (increased inotropism) are long-lasting.

journal_name

Chest

journal_title

Chest

authors

Pines A,Fisman EZ,Ayalon D,Drory Y,Averbuch M,Levo Y

doi

10.1378/chest.102.5.1496

subject

Has Abstract

pub_date

1992-11-01 00:00:00

pages

1496-8

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)59079-5

journal_volume

102

pub_type

杂志文章

相关文献

CHEST文献大全
  • Evaluation of respiratory inductive plethysmography in the measurement of breathing pattern and PEEP-induced changes in lung volume.

    abstract:STUDY OBJECTIVE:To assess the accuracy of the respiratory inductive plethysmography in the measurement of PEEP-induced changes in end-expiratory lung volume during mechanical ventilation and its accuracy and stability in the measurement of ventilation during controlled mechanical ventilation and spontaneous breathing. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.1.234

    authors: Valta P,Takala J,Foster R,Weissman C,Kinney JM

    更新日期:1992-07-01 00:00:00

  • Experimental orthotopic heart and bilateral lung transplantation completed without cardiopulmonary bypass.

    abstract:INTRODUCTION:Most experimental studies of orthotopic heart and lung graft failure are complicated by an inability to eliminate the rejection-specific inflammatory mediator from the cardiopulmonary bypass. METHODS:The following model was developed in our laboratory to investigate the feasibility of performing an orthot...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.116.5.1360

    authors: Otaki M,Inoue T,Matsumoto T,Kitayama H,Oku H

    更新日期:1999-11-01 00:00:00

  • Controlled trial of a continuous irrigation suction catheter vs conventional intermittent suction catheter in clearing bronchial secretions from ventilated patients.

    abstract::Continuous irrigation-suction catheter (Irri-cath) is a double-lumen device that allows for simultaneous saline solution infusion and aspiration. This system may theoretically be more effective than conventional dry intermittent suction due to its vortex principle. To test this hypothesis, we performed 200 suction man...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.103.4.1227

    authors: Isea JO,Poyant D,O'Donnell C,Faling LJ,Karlinsky J,Celli BR

    更新日期:1993-04-01 00:00:00

  • Factors predictive of survival among 337 patients with mesothelioma treated between 1984 and 1994 by the Cancer and Leukemia Group B.

    abstract:PURPOSE:To examine the individual and joint effect of various pretreatment clinical characteristics on the survival of patients with mesothelioma treated by the Cancer and Leukemia Group B (CALGB). PATIENTS AND METHODS:Between June 1984 and September 1994, 337 patients with malignant mesothelioma and no prior chemothe...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.113.3.723

    authors: Herndon JE,Green MR,Chahinian AP,Corson JM,Suzuki Y,Vogelzang NJ

    更新日期:1998-03-01 00:00:00

  • Fluid balance during pulmonary edema. Is fluid gain a marker or a cause of poor outcome?

    abstract:STUDY OBJECTIVE:To evaluate the importance of fluid balance and changes in extravascular lung water (EVLW) on survival in the ICU and short-term outcome in patients with pulmonary edema. DESIGN:Retrospective analysis of data (sorting by survival and "treatment received") from a recent randomized controlled trial of fl...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.100.4.1068

    authors: Schuller D,Mitchell JP,Calandrino FS,Schuster DP

    更新日期:1991-10-01 00:00:00

  • Multimodality therapy for stage IIIA (N2) lung cancer. An overview.

    abstract::Disappointing results of surgery and postoperative adjuvant chemotherapy or chemoradiotherapy in stage IIIA (N2) lung cancer have led to a number of phase II trials of induction (neoadjuvant) chemotherapy given prior to surgery. Preliminary results of 2 such studies indicate that mitomycin, vinca alkaloid, and platinu...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.103.4_supplement.356s

    authors: Ginsberg RJ

    更新日期:1993-04-01 00:00:00

  • The hypotensive effect of L-arginine is associated with increased expired nitric oxide in humans.

    abstract::Endothelial metabolism of L-arginine to L-citrulline and the potent vasodilator, nitric oxide (NO), is important in the regulation of vascular tone and resting BP. L-arginine improves abnormal endothelium-dependent vasodilation in the setting of hypercholesterolemia and has a vasodilatory effect in normal vessels, eff...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.109.6.1550

    authors: Mehta S,Stewart DJ,Levy RD

    更新日期:1996-06-01 00:00:00

  • Focus on Idiopathic Pulmonary Fibrosis: Advancing Approaches to Diagnosis, Prognosis, and Treatment.

    abstract::As seen in this CME online activity (available at http://courses.elseviercme.com/694), idiopathic pulmonary fibrosis (IPF) is a specific form of chronic, progressive, fibrotic lung disease of unknown cause that is associated with substantial health-care utilization and high rates of mortality. The clinical symptoms of...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2018.08.1021

    authors: Martinez FJ,Lederer DJ

    更新日期:2018-10-01 00:00:00

  • Treatment of Tracheobronchial Injuries: A Contemporary Review.

    abstract::Tracheobronchial injury is a rare but a potentially high-impact event with significant morbidity and mortality. Common etiologies include blunt or penetrating trauma and iatrogenic injury that might occur during surgery, endotracheal intubation, or bronchoscopy. Early recognition of clinical signs and symptoms can hel...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1016/j.chest.2018.07.018

    authors: Grewal HS,Dangayach NS,Ahmad U,Ghosh S,Gildea T,Mehta AC

    更新日期:2019-03-01 00:00:00

  • Do radiographic criteria for emphysema predict physiologic impairment?

    abstract:OBJECTIVE:The functional consequences of pulmonary emphysema have been estimated from autopsy studies. This antemortem study correlates structure as assessed by criteria applied to chest radiographs and function in earlier disease. SUBJECTS AND METHODS:Four thousand one hundred seven male shipyard and construction wor...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.107.5.1225

    authors: Kilburn KH,Warshaw RH,Thornton JC

    更新日期:1995-05-01 00:00:00

  • Treatment of diffuse tracheomalacia secondary to relapsing polychondritis with continuous positive airway pressure.

    abstract::Relapsing polychondritis (RP) is a rare disease characterized by recurrent inflammation and destruction of the cartilaginous structures. Tracheobronchial chondritis is a dreaded complication of RP. We wish to report a case of RP of the trachea and bronchi which was treated with nasal continuous positive airway pressur...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.112.6.1701

    authors: Adliff M,Ngato D,Keshavjee S,Brenaman S,Granton JT

    更新日期:1997-12-01 00:00:00

  • Contribution of craniofacial risk factors in increasing apneic activity among obese and nonobese habitual snorers.

    abstract:STUDY OBJECTIVE:To determine the role of craniofacial risk factors in increasing apneic activity between nonobese and obese habitual snorers. DESIGN:Cross-sectional. SETTING:Care-seeking volunteers identified through advertisements, and referral-based volunteers from two sleep centers serving the greater Cleveland ar...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.111.1.154

    authors: Nelson S,Hans M

    更新日期:1997-01-01 00:00:00

  • Serum KL-6 for the evaluation of active pneumonitis in pulmonary sarcoidosis.

    abstract::KL-6, a mucinous high-molecular weight glycoprotein, expressed on type II pneumonocytes, is elevated in the serum of patients with active interstitial pneumonia. Forty-seven patients with histologically confirmed sarcoidosis were analyzed by chest radiography, CT, 67Ga scintigraphy, BAL fluid (BALF), and serum KL-6. S...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.109.5.1276

    authors: Kobayashi J,Kitamura S

    更新日期:1996-05-01 00:00:00

  • Left atrial bacterial mural endocarditis.

    abstract::An unusual case of Staphylococcus aureus endocarditis confined to the mural left atrium is presented. Echocardiographic studies revealed a 1.5 x 2.0-cm vegetation mimicking a myxoma situated in the path of a mitral regurgitant jet on a color Doppler test. Emboli to upper and lower extremities and brain complicated the...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.99.3.757

    authors: Bierbrier GS,Novick RJ,Guiraudon C,Wisenberg G,Boughner D

    更新日期:1991-03-01 00:00:00

  • Subclinical cardiac dysfunction in sarcoidosis.

    abstract::Clinically apparent myocardial disease is infrequent in sarcoidosis. However, autopsy data show myocardial involvement in up to 30 percent of patients. Unexplained exertional symptomatology is a common complaint in patients with sarcoidosis. In this study, we investigated whether abnormal cardiac function might limit ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.100.1.44

    authors: Gibbons WJ,Levy RD,Nava S,Malcolm I,Marin JM,Tardif C,Magder S,Lisbona R,Cosio MG

    更新日期:1991-07-01 00:00:00

  • Myopathy following mechanical ventilation for acute severe asthma: the role of muscle relaxants and corticosteroids.

    abstract:BACKGROUND:Acute myopathy following mechanical ventilation for near-fatal asthma (NFA) has been described recently, and some researchers have suggested that this complication is related to the use of neuromuscular blocking agents (NMBAs) and corticosteroids (CSs). OBJECTIVES:To determine the incidence of acute myopath...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1378/chest.115.6.1627

    authors: Behbehani NA,Al-Mane F,D'yachkova Y,Paré P,FitzGerald JM

    更新日期:1999-06-01 00:00:00

  • Biopsy excision through a fiberoptic bronchoscope in the palliative management of airway obstruction.

    abstract::Simple biopsy resection through the rigid bronchoscope has been described in the past. We successfully performed such resection through a flexible bronchoscope in six patients with symptomatic and relatively less vascular lesions without complications. In selected patients simple biopsy resection of endobronchial lesi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.91.5.774

    authors: Mehta AC,Livingston DR

    更新日期:1987-05-01 00:00:00

  • D-dimer in acute aortic dissection.

    abstract:STUDY OBJECTIVE:Laboratory testing plays a minor role in the assessment of aortic dissection. Its main value is in the exclusion of other diseases. Following an incidental observation, we systematically investigated the relationship between elevated d-dimer levels and acute aortic dissection. DESIGN:We prospectively t...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.123.5.1375

    authors: Weber T,Högler S,Auer J,Berent R,Lassnig E,Kvas E,Eber B

    更新日期:2003-05-01 00:00:00

  • Antimicrobial therapy against Staphylococcus aureus, Pseudomonas aeruginosa, and Pseudomonas cepacia.

    abstract::The aims of antimicrobial therapy extend beyond short-term bacterial killing to long-term maintenance of weight and lung function. A review of antimicrobial drug trials shows that empiricism is still ahead of science and more studies are needed both to justify current practice and to make future changes logical. ...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.94.2_supplement.140s

    authors: Geddes DM

    更新日期:1988-08-01 00:00:00

  • The endocrinometabolic effects of beclomethasone dipropionate in asthmatic patients.

    abstract::The endocrinometabolic effects of the aerosol administration of beclomethasone dipropionate (100 microng four times daily) were evaluated in 20 asthmatic patients (11 corticodependent and nine noncorticodependent) during one month. In the noncorticodependent group, aerosol administration of beclomethasone had no stati...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.71.6.698

    authors: Yernault JC,Leclercq R,Schandevyl W,Virasoro E,De Coster A,Copinschi G

    更新日期:1977-06-01 00:00:00

  • Early detection of COPD in a high-risk population using spirometric screening.

    abstract:STUDY OBJECTIVES:To evaluate the efficacy of mass spirometry use for the detection of airflow obstruction in a high-risk population. DESIGN:Free spirometry was offered to smokers who were > 39 years of age with a smoking history of > 10 pack-years. Action was preceded by the dissemination of information on the causes ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.119.3.731

    authors: Zieliñski J,Bednarek M,Know the Age of Your Lung Study Group.

    更新日期:2001-03-01 00:00:00

  • Effect of Procalcitonin Testing on Health-care Utilization and Costs in Critically Ill Patients in the United States.

    abstract:BACKGROUND:There is a growing use of procalcitonin (PCT) to facilitate the diagnosis and management of severe sepsis. We investigated the impact of one to two PCT determinations on ICU day 1 on health-care utilization and cost in a large research database. METHODS:A retrospective, propensity score-matched multivariabl...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2016.06.046

    authors: Balk RA,Kadri SS,Cao Z,Robinson SB,Lipkin C,Bozzette SA

    更新日期:2017-01-01 00:00:00

  • Air leaks after lobectomy increase the risk of empyema but not of cardiopulmonary complications: a case-matched analysis.

    abstract:PURPOSE:To assess whether the presence and duration of air leaks after lobectomy are associated with an increased incidence of cardiopulmonary complications. METHODS:Propensity score analysis was used on 726 patients undergoing pulmonary lobectomy from 1995 through 2004 to form three well-matched pairs of patients: pa...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.130.4.1150

    authors: Brunelli A,Xiume F,Al Refai M,Salati M,Marasco R,Sabbatini A

    更新日期:2006-10-01 00:00:00

  • High-intensity physical training in adults with asthma. A 10-week rehabilitation program.

    abstract::Twenty-six adults (23 to 58 years) with mild to moderate asthma underwent a 10-week supervised rehabilitation program, with emphasis on physical training. In the first 2 weeks, they exercised daily in an indoor swimming pool (33 degrees C) and received education about asthma, medication, and principles of physical tra...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.109.2.323

    authors: Emtner M,Herala M,Stålenheim G

    更新日期:1996-02-01 00:00:00

  • Dynamic hyperinflation during bronchoconstriction in asthma: implications for symptom perception.

    abstract:OBJECTIVE:The objective of this study was to examine the relationship between respiratory symptom intensity and quality and dynamic lung hyperinflation (DH) during induced bronchoconstriction in asthma. PATIENTS AND METHODS:Subjects with asthma (n = 116) underwent baseline spirometry and lung volume measurement follow...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.130.4.1072

    authors: Lougheed MD,Fisher T,O'Donnell DE

    更新日期:2006-10-01 00:00:00

  • Frequency of pleural effusions in patients with pulmonary arterial hypertension associated with connective tissue diseases.

    abstract:BACKGROUND:Pleural effusions frequently accumulate in patients with left-sided heart failure. However, our recent study in patients with idiopathic and heritable pulmonary arterial hypertension (PAH) demonstrated that pleural effusions frequently occur in patients with isolated right-sided heart failure (RHF). The obje...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.10-0227

    authors: Luo YF,Robbins IM,Karatas M,Brixey AG,Rice TW,Light RW

    更新日期:2011-07-01 00:00:00

  • Pulmonary Hypertension in Parenchymal Lung Diseases: Any Future for New Therapies?

    abstract::Pulmonary hypertension (PH) due to chronic lung disease is associated with a poor prognosis, regardless of the underlying respiratory condition. Updated PH guidelines recommend optimal treatment of the underlying lung disease, including long-term oxygen therapy, in patients with chronic hypoxemia despite the lack of r...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1016/j.chest.2017.06.008

    authors: Harari S,Elia D,Humbert M

    更新日期:2018-01-01 00:00:00

  • Intrapleural recombinant IL-2 in passive immunotherapy for malignant pleural effusion.

    abstract::The purpose of this phase 1 study was to determine the toxicity and effectiveness of recombinant interleukin-2 (RU 49637 Roussel Uclaf-France) administered by continuous pleural infusion for 5 days to patients with different histologic subtypes of pleural cancer. Incremental doses of rIL-2 from 3 x 10(6) to 24 x 10(6)...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.103.1.209

    authors: Astoul P,Viallat JR,Laurent JC,Brandely M,Boutin C

    更新日期:1993-01-01 00:00:00

  • Safety of long-term treatment with HFA albuterol.

    abstract:BACKGROUND:Chlorofluorocarbons (CFCs) used as propellants in metered-dose inhalers deplete stratospheric ozone, which results in serious public health concerns. Albuterol has been reformulated in the non-ozone-depleting propellant, hydrofluoroalkane-134a (HFA albuterol). OBJECTIVES:The primary objective was to compare...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.115.4.945

    authors: Ramsdell JW,Klinger NM,Ekholm BP,Colice GL

    更新日期:1999-04-01 00:00:00

  • Histologic assessment of tumor-associated CD45(+) cell numbers is an independent predictor of prognosis in small cell lung cancer.

    abstract:BACKGROUND:Small cell lung carcinoma (SCLC) continues to have a poor prognosis, with a 2-year survival of < 20%. Studies have suggested that SCLC may affect the immune system to allow it to evade immunologic responses. We hypothesized that any such effect would be characterized by a decrease in the lymphoid cells assoc...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.12-0681

    authors: Wang W,Hodkinson P,McLaren F,Mackean MJ,Williams L,Howie SEM,Wallace WAH,Sethi T

    更新日期:2013-01-01 00:00:00