Pulmonary Hypertension in Parenchymal Lung Diseases: Any Future for New Therapies?

abstract：BACKGROUND:Acute myopathy following mechanical ventilation for near-fatal asthma (NFA) has been described recently, and some researchers have suggested that this complication is related to the use of neuromuscular blocking agents (NMBAs) and corticosteroids (CSs). OBJECTIVES:To determine the incidence of acute myopath...

journal_title：Chest

authors： Behbehani NA,Al-Mane F,D'yachkova Y,Paré P,FitzGerald JM

更新日期：1999-06-01 00:00:00

abstract：:This report describes a patient in whom pericardial effusion, two months after coronary bypass surgery, mimicked the presence of a left atrial mass on both echocardiography and cardiac angiography. ...

journal_title：Chest

authors： Steffenino G,Ferrero G,Forni B,Giustetto C,Ottino G,Conte M

更新日期：1989-02-01 00:00:00

abstract：:This type of pulmonary venous infarction has not been previously reported, namely: pulmonary vein obstruction from squamous cell carcinoma. Furthermore, this case is unique in that the characteristic pathologic vascular changes observed with pulmonary venous infarction were contrasted with a noninfarcted upper lobe th...

journal_title：Chest

authors： Williamson WA,Tronic BS,Levitan N,Webb-Johnson DC,Shahian DM,Ellis FH Jr

更新日期：1992-09-01 00:00:00

abstract：:We studied the possibility of predicting PaO2 during exercise of a given oxygen uptake (VO2) from resting pulmonary function tests (PFTs) in patients with chronic obstructive pulmonary disease (COPD). The three-minute incremental treadmill exercise was performed with serial measurements of PaO2 via intra-arterial cath...

journal_title：Chest

authors： Kurihara N,Fujimoto S,Terakawa K,Yamamoto M,Takeda T

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVE:Fractional flow reserve (FFR) is a valid surrogate for hemodynamic significance in stenotic native coronary arteries, but its validity in patients with coronary stent restenosis is unknown. DESIGN:Prospective. SETTING:University hospital. PATIENTS:We studied 42 patients (mean age +/- 1 SD, 62 +/- 10 years)...

journal_title：Chest

authors： Krüger S,Koch KC,Kaumanns I,Merx MW,Hanrath P,Hoffmann R

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify the CT scan features that predict patient outcome after reexpansion procedures in patients with the fibrotic stage of endobronchial TB. METHODS:We retrospectively enrolled 30 patients (four men, 26 women) aged 32 +/- 11 years who had lobar or whole-lung atelectasis ...

journal_title：Chest

authors： Lee JY,Yi CA,Kim TS,Kim H,Kim J,Han J,Kwon OJ,Lee KS,Chung MJ

更新日期：2010-08-01 00:00:00

abstract：:Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) can reliably sample enlarged mediastinal lymph nodes in patients with non-small cell lung cancer (NSCLC), and in practice is mostly used to sample nodes visible on CT or positron emission tomography (PET). Few data are available on the use of...

journal_title：Chest

authors： Herth FJ,Eberhardt R,Krasnik M,Ernst A

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Peak exercise oxygen consumption (peak VO2), which is considered an indicator of prognosis in advanced heart failure, is currently being used as a major criterion in many centers for the selection of candidates for heart transplantation. Available studies suggest that patients with peak VO2 < 14 mL/min/kg ha...

journal_title：Chest

authors： Ramos-Barbón D,Fitchett D,Gibbons WJ,Latter DA,Levy RD

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:To address the major methodological issues of reverse causation and selection bias in epidemiologic studies of antibiotic use in early life and the development of asthma, we undertook a cohort study of this association in a complete population of children. METHODS:Using the health-care and prescription data...

journal_title：Chest

authors： Kozyrskyj AL,Ernst P,Becker AB

更新日期：2007-06-01 00:00:00

abstract：STUDY OBJECTIVE:To assess whether myocardial contrast echocardiography (MCE) using harmonic power Doppler (HPD) in conjunction with the transvenous contrast agent SHU 563A would be useful in detecting stunned but viable myocardium. DESIGN:Acute coronary occlusion (2 to 3 h) followed by 1 h of reperfusion was created i...

journal_title：Chest

authors： Teupe C,Takeuchi M,Yao J,Avelar E,Pandian N

更新日期：2001-08-01 00:00:00

abstract：STUDY OBJECTIVES:The aim of this study was to evaluate the immediate and midterm results of coronary artery bypass grafting with the radial artery (RA) as a conduit. PATIENTS:Two hundred forty-one patients underwent myocardial revascularization using the RA. In 78.5% of patients, three coronary vessels were involved, ...

journal_title：Chest

authors： Beghi C,Nicolini F,Budillon AM,Borrello B,Ballore L,Reverberi C,Gherli T

更新日期：2002-12-01 00:00:00

abstract：:We report 4 cases of Churg-Strauss syndrome (CSS) that occurred in patients being treated with corticosteroids for a diagnosis of asthma. One patient had asthma, eosinophilia, and eosinophilic lymphadenopathy that regressed with higher doses of corticosteroids. The second patient had both eosinophilic tissue infiltrat...

journal_title：Chest

authors： Churg A,Brallas M,Cronin SR,Churg J

更新日期：1995-08-01 00:00:00

abstract：:The chest wall is an uncommon localization for hydatid cyst. In this article, six patients were operated on because of chest wall hydatid cysts between the years 1989 to 1991 have been reported. Four of them had previously undergone surgery for pulmonary or hepatic hydatidosis; the chest wall was the primary site in t...

journal_title：Chest

authors： Ozdemir N,Akal M,Kutlay H,Yavuzer S

更新日期：1994-04-01 00:00:00

abstract：STUDY OBJECTIVES:Sialomucin complex (SMC) is a heterodimeric glycoprotein, and is found on the surfaces of the mesothelia of the pleura, pericardium, and peritoneum. Sialomucins play a significant role in adhesion as well as in defense. In this study, we hypothesized that pleural mesothelial cells (PMCs) express SMC an...

journal_title：Chest

authors： Sharma RK,Mohammed KA,Nasreen N,Hardwick J,Van Horn RD,Ramirez-Icaza C,Antony VB

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Whether the localization of nonmassive pulmonary embolism (PE) is associated with the short-term and long-term prognosis of patients remains unknown. Our aim was to characterize associations of nonmassive PE localization with risks of recurrent VTE, major bleeding, and mortality during and after anticoagulat...

journal_title：Chest

authors： Gouin B,Blondon M,Jiménez D,Fernández-Capitán C,Bounameaux H,Soler S,Duce R,Sahuquillo JC,Ruiz-Giménez N,Monreal M,RIETE investigators.

更新日期：2017-04-01 00:00:00

abstract：STUDY OBJECTIVE:We assessed whether transpleural methods for diagnosing peripheral lung cancer, such as needle aspiration or tumor excision, affect relapse and prognosis, because these techniques have potential to spread malignant cells from the tumor. DESIGN:A retrospective study. SETTING:National referral hospital....

journal_title：Chest

authors： Sawabata N,Maeda H,Ohta M,Hayakawa M

更新日期：2001-11-01 00:00:00

abstract：:The aim of this prospective study was to determine the rate of recurrence for spontaneous pneumothorax (SP) after tetracycline pleurodesis (TCP), using that of observation, tube thoracostomy alone, and thoracotomy as references. From 1985 to the end of 1991, 78 patients were treated with tetracycline pleurodesis and 1...

journal_title：Chest

authors： Alfageme I,Moreno L,Huertas C,Vargas A,Hernandez J,Beiztegui A

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Increased expression of the human epididymis protein 4 (HE4) was previously described in lung biopsy samples from patients with cystic fibrosis (CF). It remains unknown, however, whether serum HE4 concentrations are elevated in CF. METHODS:Seventy-seven children with CF from six Hungarian CF centers and 57 ...

journal_title：Chest

authors： Nagy B Jr,Nagy B,Fila L,Clarke LA,Gönczy F,Bede O,Nagy D,Újhelyi R,Szabó Á,Anghelyi A,Major M,Bene Z,Fejes Z,Antal-Szalmás P,Bhattoa HP,Balla G,Kappelmayer J,Amaral MD,Macek M Jr,Balogh I

更新日期：2016-09-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the intraoperative evolution of patients with COPD during lung resection and to test whether exercise testing could be helpful in the prediction of the intraoperative course. DESIGN:Prospective study. SETTING:University teaching hospital. PATIENTS:Forty patients (mean [+/- SD] age, 65 +/...

journal_title：Chest

authors： Ribas J,Jiménez MJ,Barberà JA,Roca J,Gomar C,Canalís E,Rodriguez-Roisin R

更新日期：2001-09-01 00:00:00

abstract：:Eighty-two patients with mitral stenosis underwent cardiac catheterization with coronary angiography. Twenty-one patients (26 percent) had coronary artery disease. Characteristics of the mitral valve area, cardiac output, pulmonary artery pressure, pulmonary vascular resistance, left ventricular end-diastolic pressure...

journal_title：Chest

authors： Chun PK,Gertz E,Davia JE,Cheitlin MD

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:A comprehensive evaluation of temporal trends in the treatment of patients who have DVT may assist with identification of modifiable factors that contribute to short-term outcomes. METHODS:We assessed temporal trends in length of hospital stay and use of pharmacological and interventional therapies among 26...

journal_title：Chest

authors： Morillo R,Jiménez D,Aibar MÁ,Mastroiacovo D,Wells PS,Sampériz Á,Saraiva de Sousa M,Muriel A,Yusen RD,Monreal M,RIETE investigators.

更新日期：2016-08-01 00:00:00

abstract：:An international, multicenter, prospective survey has been conducted to determine the hospital survival rates of patients with potentially reversible acute respiratory failure (ARF) who are managed in sophisticated intensive care units by leading critical care specialists, using current (1991 to 1992) support and trea...

journal_title：Chest

authors： Vasilyev S,Schaap RN,Mortensen JD

更新日期：1995-04-01 00:00:00

abstract：:Acute elevation of the ST segment in several ECG leads was observed in seven patients with bacterial shock during the course of therapy. Six patients had bacterial pneumonia, one had acute cholecystitis, and none had a previous history of heart disease. At the onset of the ST elevation, all patients were receiving dop...

journal_title：Chest

authors： Terradellas JB,Bellot JF,Sarís AB,Gil CL,Torrallardona AT,Garriga JR

更新日期：1982-04-01 00:00:00

abstract：STUDY OBJECTIVE:To assess the utility of urinary uric acid excretion as a marker of nocturnal hypoxia in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) before and after the institution of nasal continuous positive airway pressure (CPAP). DESIGN:Prospective, open. SETTING:Sleep Disorders Laboratory, V...

journal_title：Chest

authors： Sahebjani H

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:To assess whether severe gastroesophageal reflux (GER) is associated with abnormalities in lung function including measures of lung volume and gas diffusion. METHODS:Data from 147 patients with obesity (body mass index [BMI] range, 31.7 to 70 kg/m(2)) who presented for obesity surgery was analyzed retrospect...

journal_title：Chest

authors： Schachter LM,Dixon J,Pierce RJ,O'Brien P

更新日期：2003-06-01 00:00:00

abstract：:Rupture of the left ventricular free wall after acute myocardial infarction (AMI) has been regarded as uniformly fatal unless emergency surgical repair is performed. Among 2,862 patients admitted with AMI to our ICU during the last 8 years, 107 patients developed rupture of the left ventricular free wall. Twenty-nine ...

journal_title：Chest

authors： Blinc A,Noc M,Pohar B,Cernic N,Horvat M

更新日期：1996-02-01 00:00:00

abstract：:In 14 consecutive patients with varying myocardial function, evaluation of the Valsalva maneuver was performed using aortic pulse pressure decay to investigate a possible quantitative relationship between the pattern of response and the degree of myocardial dysfunction. The aortic pulse pressure response during strain...

journal_title：Chest

authors： Bernardi L,Saviolo R,Spodick DH

更新日期：1989-05-01 00:00:00

abstract：:Gastrointestinal complications requiring surgical correction following cardiopulmonary bypass most frequently involve the upper gastrointestinal tract. Surgical diseases of the colon are quite unusual in this setting. We recently performed cardiac surgery on three patients who developed acute diverticulitis requiring ...

journal_title：Chest

authors： Burton NA,Albus RA,Graeber GM,Lough FC

更新日期：1986-05-01 00:00:00

abstract：STUDY OBJECTIVE:Immune and inflammatory mechanisms could play a significant role in pulmonary arterial hypertension (PAH) genesis or progression, especially in patients with connective tissue diseases. Immunosuppressive therapy should be better evaluated in this setting. STUDY DESIGN:Monocentric retrospective study. ...

journal_title：Chest

authors： Sanchez O,Sitbon O,Jaïs X,Simonneau G,Humbert M

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:COPD is characterized by chronic inflammation. In vitro and ex vivo observations suggest that this inflammatory response is partially resistant to the effect of corticosteroids and that low-dose theophylline can restore this response via enhancement of histone deacetylase (HDAC) activity. Whether this occurs...

journal_title：Chest

authors： Cosío BG,Shafiek H,Iglesias A,Yanez A,Córdova R,Palou A,Rodriguez-Roisin R,Peces-Barba G,Pascual S,Gea J,Sibila O,Barnes PJ,Agusti A

更新日期：2016-07-01 00:00:00