Abstract:
:The relation between allergy and risk of cancer was evaluated in a cohort study of 34,198 Seventh-day Adventists in California. Information on prevalence of asthma, hay fever, and reactions to chemicals, medications, bee stings, and poison oak (or ivy) was obtained by questionnaire in 1976. The reported allergies must have been serious enough to require treatment by a physician. The cohort was then followed for 6 years (1977-1982). Both stratified analysis and Cox proportional hazards regression analyses were utilized to evaluate the relation of allergy to cancer after taking into account several potentially confounding variables. For all cancer sites combined in males, there was a 33% increased risk associated with reaction to medications. In contrast, among females, reaction to medications was associated with a 21% decrease in risk. Both results were statistically significant. Prostate and breast cancer risk were elevated in persons who reported any type of allergic history, as was risk of lymphatic or hematopoietic cancers and sarcoma. For each of these types of cancer, risk increased with increasing numbers of allergies. However, ovarian cancer risk was decreased in persons with any allergic history and increasing numbers of allergies was associated with decreasing risk of this form of cancer. These results suggest that the association between allergy and cancer is complex and depends on the specific allergy and the specific organ site under consideration.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Mills PK,Beeson WL,Fraser GE,Phillips RLdoi
10.1093/oxfordjournals.aje.a116494subject
Has Abstractpub_date
1992-08-01 00:00:00pages
287-95issue
3eissn
0002-9262issn
1476-6256journal_volume
136pub_type
杂志文章abstract::Recent studies have suggested that bone mineral density (BMD) is related to risk of breast cancer in elderly women. This study investigated whether the level of breast cancer risk associated with BMD in women with a positive family history of breast cancer is different from that in women without a family history of br...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a009554
更新日期:1998-07-01 00:00:00
abstract::When researching racial disparities in health, residential segregation cannot be ignored. Because of segregation, contextual differences by race are so pronounced that ignoring them may lead to mis-estimating the effect of individual-level factors. However, given the stark racial separation of social contexts, researc...
journal_title:American journal of epidemiology
pub_type: 评论,杂志文章
doi:10.1093/aje/kwn290
更新日期:2008-12-01 00:00:00
abstract::The authors assessed the influence of age, period, and cohort effects on rates of preterm delivery in the United States. Rates of preterm delivery for singleton births (<37 weeks) in seven age groups (15-19, 20-24,., 45-49 years), five periods (1975, 1980, 1985, 1990, 1995), and 11 maternal birth cohorts (1926-1930, 1...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/154.7.657
更新日期:2001-10-01 00:00:00
abstract::The impact of summertime haze episodes on daily variations in symptoms and peak expiratory flow rates (PEFRs) was examined in a study of 108 children living in State College, Pennsylvania, during the summer of 1991. Twice daily, each child recorded symptoms, PEFRs and hours spent outdoors. Environmental measurements i...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a008818
更新日期:1996-04-15 00:00:00
abstract::In this paper, the authors report on the design of a population-based case-control study of family history as a risk factor for coronary heart disease (CHD). They studied the characteristics of subjects who completed a detailed family history questionnaire in 1992-1994 as well as the accuracy of recall of family histo...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a009410
更新日期:1998-06-15 00:00:00
abstract::To assess recall of childhood socioeconomic position for public health research, the authors conducted a cross-sectional study of 352 adult women twin pairs enrolled in Examination II of the Kaiser Permanente Women Twins Study carried out in 1989-1990 in Oakland, California. Among twin pairs, 91% (95% confidence inter...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a009512
更新日期:1998-04-01 00:00:00
abstract::Mean levels of total cholesterol by sex and age were compared between groups of whites in visit 2 of the Lipid Research Clinics Program Prevalence Study and in the second National Health and Nutrition Examination Survey (NHANES II). NHANES II estimates were found to be higher than comparable visit 2 estimates by 3-14 ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115048
更新日期:1988-11-01 00:00:00
abstract::Accumulation of mitochondrial DNA (mtDNA) mutations leads to alterations of mitochondrial biogenesis and function that might produce a decrease in mtDNA content within cells. This implies that mtDNA content might be a potential biomarker associated with oxidative stress and inflammation. However, data on correlates of...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwv175
更新日期:2016-01-15 00:00:00
abstract::Bias due to selective mortality is a potential concern in many studies and is especially relevant in cognitive aging research because cognitive impairment strongly predicts subsequent mortality. Biased estimation of the effect of an exposure on rate of cognitive decline can occur when mortality is a common effect of e...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwv451
更新日期:2016-09-01 00:00:00
abstract::Vaccinating school-aged children against influenza can reduce age-specific and population-level illness attack rates. Using a stochastic simulation model of influenza transmission, the authors assessed strategies for vaccinating children in the United States, varying the vaccine type, coverage level, and reproductive ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwp237
更新日期:2009-09-15 00:00:00
abstract::There is little current understanding of the risk for occurrence of unintentional injury in the home. The authors estimated the incidence of unintentional home injuries for an entire community, adjusting for actual time spent awake in the home and, in addition, analyzed the costs of these injuries. Cases of unintentio...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a008951
更新日期:1996-09-01 00:00:00
abstract::Some studies have suggested that eating patterns, which describe eating frequency, the temporal distribution of eating events across the day, breakfast skipping, and the frequency of eating meals away from home, may be related to obesity. Data from the Seasonal Variation of Blood Cholesterol Study (1994-1998) were use...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwg117
更新日期:2003-07-01 00:00:00
abstract::Previous studies, mainly among populations with high consumption of seafood, have suggested that increased marine n-3 polyunsaturated fatty acid (PUFA) intake during pregnancy promotes longer gestation and higher birth weight. Few studies have isolated the contribution of fetal growth to birth weight. Using data from ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwh282
更新日期:2004-10-15 00:00:00
abstract::A prevalence study was designed to evaluate host and seasonal risk factors associated with three systemic mycoses in dogs: blastomycosis, coccidioidomycosis, and histoplasmosis. Histoplasmosis was the most commonly diagnosed of the three diseases. All three of the mycoses occurred more frequently in male than female d...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113077
更新日期:1981-02-01 00:00:00
abstract::To understand whether neighborhood contexts contribute to the onset or maintenance of mental health problems independently of individual characteristics requires the use of multilevel study designs and analytical strategies. This study used a multilevel analytical framework to examine the relation between neighborhood...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwi185
更新日期:2005-08-01 00:00:00
abstract::A number of prospective cohort studies have examined the relations of individual dietary variables to risk of colorectal cancer. Few studies have addressed the broader eating patterns that reflect many dietary exposures working together. Using data from a prospective study of 61,463 women, with an average follow-up pe...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/154.12.1143
更新日期:2001-12-15 00:00:00
abstract::The authors assessed the association between cognitive function and incidence and maintenance of overweight in preschool children. A population-based birth cohort was established in Menorca, Spain, between 1997 and 1999 (n = 482). Body mass index (weight (kg)/height (m)(2)) was measured at ages 4 years and 6 years (n ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwp140
更新日期:2009-08-15 00:00:00
abstract::The relationship of the risk of cancer and death to total serum cholesterol was studied in a random population sample from two counties of Eastern Finland. Data on total serum cholesterol were recorded between February and April 1972 for 3745 men and 4221 women aged 30 to 59 years who had no history of cancer, diabete...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113445
更新日期:1982-10-01 00:00:00
abstract::There is growing interest in understanding how food environments affect diet, but characterizing the food environment is challenging. The authors investigated the relation between global diet measures (an empirically derived "fats and processed meats" (FPM) dietary pattern and the Alternate Healthy Eating Index (AHEI)...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwm394
更新日期:2008-04-15 00:00:00
abstract::The safety and immunogenicity of a plasma-derived heat-inactivated hepatitis B vaccine (CLB) were evaluated in 471 healthy human volunteers, who, both in their occupations and in their private lives, had been at minimal risk of being infected with hepatitis B virus. The first 202 individuals received three 3-microgram...
journal_title:American journal of epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/oxfordjournals.aje.a113936
更新日期:1984-11-01 00:00:00
abstract::A comparison between prescriber records and patient-reported oral contraceptive histories obtained during a case-control study of thromboembolism and oral contraceptive use served as the basis for evaluating the extent of agreement between these two sources of information. Agreement between oral contraceptive user and...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a112529
更新日期:1978-03-01 00:00:00
abstract::This study examines the impact of military service on 13 categories of self-reported physical health problems by using a sample of 2,260 American male-male monozygotic twin pairs who served on active duty during the Vietnam War. Data were collected in 1987 by using mail and/or telephone interviews. Twins who served in...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115992
更新日期:1991-07-01 00:00:00
abstract::Studies from the United States have shown increasing incidence of autism spectrum disorder (ASD) with increasing socioeconomic status (SES), whereas in Scandinavian countries, no such relation was identified. We investigated how ASD risk in offspring varied according to parental SES in Taiwan, where we have universal ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwaa241
更新日期:2020-10-31 00:00:00
abstract::The Baltimore-Washington Infant Study, a case-control study of congenital heart defects in liveborn infants conducted in 1981--1989, interviewed parents about a wide range of environmental exposures that occurred during and before the pregnancy. In the period 1987--1989, the questionnaire was expanded to include a det...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/153.6.529
更新日期:2001-03-15 00:00:00
abstract::The case-only design, which requires only diseased subjects, allows for estimation of multiplicative interactions between factors known to be independent in the study population. The design is being used as an alternative to the case-control design to study gene-environment interactions. Estimates of gene-environment ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/154.8.687
更新日期:2001-10-15 00:00:00
abstract::The link between blood pressure measured at juvenile ages (3-18 years) and subsequent adult ages (30 and 50 years) was investigated in a community-based longitudinal study conducted in the San Francisco Bay Area from 1928 to the present. The original sample of 550 persons decreased 61 percent by age 50 years, leaving ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a116543
更新日期:1992-09-15 00:00:00
abstract::A prospective panel cohort design was used to investigate whether mental disorders common in the general population increase the likelihood of increased cigarette smoking at 12 months follow-up. By 1995, the last year for which data were available, a random sample of 12,057 persons aged 16-75 years residing in private...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/152.7.651
更新日期:2000-10-01 00:00:00
abstract::Infectious transmission of streptococci in families has been demonstrated to follow Greenwood's chain-binomial model in its simplest form which did not need beta transformation to correct for differences in susceptibility between families. Following the application of this model, an estimate of the risk of acquisition...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a112677
更新日期:1979-02-01 00:00:00
abstract::Daily temperatures and snowfall were related to coronary and stroke deaths in selected standard metropolitan statistical areas for the 5-year period 1962-1966. Typically an inverse approximately linear pattern of coronary heart disease (CHD) and of stroke mortality with temperature was seen over the greater part of th...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a112261
更新日期:1976-06-01 00:00:00
abstract::The authors present results from a novel approach to understanding recent secular trends in overweight in terms of changes in underlying component distributions. On the basis of an examination of two large overlapping samples of Danish young men (ns = 16,557 and 21,747) spanning birth cohorts 1939-1958, the authors fo...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115917
更新日期:1991-03-01 00:00:00