Epidural clonidine relieves intractable neuropathic itch associated with herpes zoster-related pain.

Abstract:

OBJECTIVE:We present a case of intense herpes zoster-related pain and itching in the ophthalmic division of the trigeminal nerve (V1). Successful pain and itch management was achieved after insertion of a high thoracic epidural catheter with a continuous infusion of bupivacaine and clonidine. CASE REPORT:A 73-year-old woman with metastatic malignant melanoma developed acute herpes zoster-related pain and itching unresponsive to conventional oral medications. The patient described severe and frequent attacks of lancinating pain occurring in the dermatomal distribution of the left ophthalmic division of the trigeminal nerve. She also had a disturbing itch in the same distribution as her pain. The patient had significant reduction in the frequency and intensity of the lancinating attacks after placement of a thoracic epidural catheter with continuous infusion of 1 microg/mL clonidine and 0.05% bupivacaine. The itching resolved completely as well. CONCLUSION:High thoracic epidural infusion of bupivacaine and clonidine was beneficial in relieving neuropathic itch in a patient with acute herpes zoster-related pain in the distribution of the trigeminal nerve.

journal_name

Reg Anesth Pain Med

authors

Elkersh MA,Simopoulos TT,Malik AB,Cho EH,Bajwa ZH

doi

10.1016/s1098-7339(03)00182-2

subject

Has Abstract

pub_date

2003-07-01 00:00:00

pages

344-6

issue

4

eissn

1098-7339

issn

1532-8651

pii

S1098733903001822

journal_volume

28

pub_type

杂志文章
  • Adverse Drug Effects and Preoperative Medication Factors Related to Perioperative Low-Dose Ketamine Infusions.

    abstract::High-dose opioid administration is associated with significant adverse events. Evidence suggests that low-dose ketamine infusions improve perioperative analgesia over conventional opioid management, but usage is highly variable. Ketamine's adverse drug effects (ADEs) are well known, but their prevalence during low-dos...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1097/AAP.0000000000000416

    authors: Schwenk ES,Goldberg SF,Patel RD,Zhou J,Adams DR,Baratta JL,Viscusi ER,Epstein RH

    更新日期:2016-07-01 00:00:00

  • The peripheral analgesic effect of meperidine in reducing propofol injection pain is not naloxone-reversible.

    abstract:BACKGROUND AND OBJECTIVES:Meperidine is frequently used in general anesthesia and perioperative analgesia. In addition to its opioid action, meperidine possesses some local anesthetic properties. A preliminary study using the tourniquet venous retention technique found meperidine to be more effective in reducing propof...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00115550-199823020-00014

    authors: Pang WW,Mok MS,Huang S,Chung YT,Hwang MH

    更新日期:1998-03-01 00:00:00

  • Dexamethasone and dexmedetomidine as adjuvants to local anesthetic mixture in intercostal nerve block for thoracoscopic pneumonectomy: a prospective randomized study.

    abstract:BACKGROUND AND OBJECTIVES:Perineural dexamethasone or dexmedetomidine prolongs the duration of single-injection peripheral nerve block when added to the local anesthetic solution. In a randomized, controlled, double-blinded study in patients undergoing thoracoscopic pneumonectomy, we tested the hypothesis that combined...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1136/rapm-2018-100221

    authors: Zhang P,Liu S,Zhu J,Rao Z,Liu C

    更新日期:2019-08-08 00:00:00

  • Effect of acute versus continuous glycemic control on duration of local anesthetic sciatic nerve block in diabetic rats.

    abstract:BACKGROUND AND OBJECTIVES:The duration of nerve block is longer in streptozotocin (STZ)-induced diabetic rats for all local anesthetics (with and without adjuvants) compared with normal rats. Perioperative glycemic control is currently practiced to reduce adverse events in many at-risk patients, especially in diabetic ...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1097/AAP.0b013e31826742fd

    authors: Kroin JS,Buvanendran A,Tuman KJ,Kerns JM

    更新日期:2012-11-01 00:00:00

  • A Randomized Comparison Between Single- and Triple-Injection Subparaneural Popliteal Sciatic Nerve Block.

    abstract:BACKGROUND AND OBJECTIVES:This prospective randomized trial compared ultrasound-guided single-injection (SI) and triple-injection (TI) subparaneural popliteal sciatic nerve block. We hypothesized that multiple injections are not required when local anesthetic (LA) is deposited under the paraneurium because the latter e...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/AAP.0000000000000253

    authors: Tiyaprasertkul W,Bernucci F,González AP,Leurcharusmee P,Yazer MS,Techasuk W,Arnuntasupakul V,de la Garza DC,Finlayson RJ,Tran DQ

    更新日期:2015-07-01 00:00:00

  • Intrathecal labor analgesia with bupivacaine and sufentanil: the effect of adding 2.25 microg epinephrine.

    abstract:BACKGROUND AND OBJECTIVES:Epinephrine, 25 microg and 200 microg, has been found to prolong the duration of intrathecal labor analgesia when added to an opioid. In our hospital we use the standard epidural mixture, prepared by the pharmacist, containing epinephrine 1:800,000; i.e., 1.25 microg/mL for both spinal and epi...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1053/rapm.2001.24406

    authors: Vercauteren MP,Jacobs S,Jacquemyn Y,Adriaensen HA

    更新日期:2001-09-01 00:00:00

  • Antinociceptive and motor-blocking action of epidurally administered IQB-9302 and bupivacaine in the dog.

    abstract:BACKGROUND AND OBJECTIVES:The aim of this study was to compare the antinociceptive and motor-blocking effects of epidurally administered IQB-9302 (C18H26N2O.HCl) and bupivacaine in the dog. METHODS:Twelve adult female Beagle dogs were used. Each animal received 3 concentrations (0.25%, 0.50%, and 0.75%) of either IQB-...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:

    authors: Gómez de Segura IA,Vazquez I,De Miguel E

    更新日期:2000-09-01 00:00:00

  • Evaluation of the iPACK block injectate spread: a cadaveric study.

    abstract:BACKGROUND AND OBJECTIVES:Ultrasound-guided infiltration of the interspace between the popliteal artery and capsule of the knee (iPACK) block, a new regional analgesic technique, is believed to relieve posterior knee pain, after total knee arthroplasty, by targeting the articular branches innervating posterior aspect o...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1136/rapm-2018-100355

    authors: Tran J,Giron Arango L,Peng P,Sinha SK,Agur A,Chan V

    更新日期:2019-05-06 00:00:00

  • In vitro antagonism of recombinant ligand-gated ion-channel receptors by stereospecific enantiomers of bupivacaine.

    abstract:BACKGROUND AND OBJECTIVES:Bupivacaine is a racemic mixture of S(-)- and R(+)-enantiomers. Both isomers have similar potency as local anesthetics, but the S(-)-enantiomer produces less central nervous system and cardiovascular toxicity. Local anesthetic-induced convulsion is likely to be associated with not only sodium ...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1016/j.rapm.2005.09.004

    authors: Ueta K,Sugimoto M,Suzuki T,Uchida I,Mashimo T

    更新日期:2006-01-01 00:00:00

  • Electron-microscopic imaging of endothoracic fascia in the thoracic paravertebral space in rats.

    abstract:BACKGROUND AND OBJECTIVES:Anesthesia and analgesia with paravertebral block are reportedly variable. Existence of an endothoracic fascia has been proposed as one of the possible mechanisms leading to variability. We undertook an electron-microscopy imaging study to investigate the endothoracic fascia in the thoracic pa...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1097/AAP.0b013e31824451cb

    authors: Stopar Pintaric T,Veranic P,Hadzic A,Karmakar M,Cvetko E

    更新日期:2012-03-01 00:00:00

  • A Cadaveric Study of Ultrasound-Guided Maxillary Nerve Block Via the Pterygopalatine Fossa: A Novel Technique Using the Lateral Pterygoid Plate Approach.

    abstract:BACKGROUND AND OBJECTIVES:This study aimed to describe and assess the accuracy and feasibility of a novel technique for ultrasound-guided maxillary nerve block using the lateral pterygoid plate (LPP) approach via the pterygopalatine fossa (PPF) in a soft cadaveric model. METHODS:Ten soft cadavers were studied. The cur...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/AAP.0000000000000790

    authors: Kampitak W,Tansatit T,Shibata Y

    更新日期:2018-08-01 00:00:00

  • HTX-011 reduced pain intensity and opioid consumption versus bupivacaine HCl in bunionectomy: phase III results from the randomized EPOCH 1 study.

    abstract:BACKGROUND AND OBJECTIVES:There is a need for local anesthetics that provide consistent analgesia through 72 hours after surgery. This study evaluates the use of HTX-011 (bupivacaine and meloxicam in Biochronomerpolymer technology), an extended-release, dual-acting local anesthetic, in reducing both postoperative pain ...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1136/rapm-2019-100531

    authors: Viscusi E,Gimbel JS,Pollack RA,Hu J,Lee GC

    更新日期:2019-05-21 00:00:00

  • Epidural fentanyl speeds the onset of sensory block during epidural lidocaine anesthesia.

    abstract:BACKGROUND AND OBJECTIVES:Shortening the onset time of sensory block is a practical goal to improve the quality of epidural anesthesia. The addition of fentanyl to a local anesthetic solution is widely used during epidural anesthesia. This randomized double-blind study examined the onset time of sensory block during ep...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1053/rapm.2001.27852

    authors: Cherng CH,Wong CS,Ho ST

    更新日期:2001-11-01 00:00:00

  • Median effective local anesthetic doses of plain bupivacaine and ropivacaine for spinal anesthesia administered via a spinal catheter for brachytherapy of the lower abdomen.

    abstract:BACKGROUND AND OBJECTIVES:Continuous spinal anesthesia via a spinal catheter allows adjusting the duration and extent of anesthesia to surgical needs, maintenance of hemodynamic stability, and good postoperative analgesia. This study was designed to determine the median effective local anesthetic dose of plain ropivaca...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.rapm.2007.06.396

    authors: Michalek-Sauberer A,Kozek-Langenecker SA,Heinzl H,Deusch E,Chiari A

    更新日期:2008-01-01 00:00:00

  • Ganglionic local opioid application (GLOA) for treatment of chronic headache and facial pain.

    abstract:OBJECTIVE:This report describes the effects of ganglionic local opioid application (GLOA) in patients with chronic headache and persistent idiopathic facial pain. CASE REPORT:We present 2 patients with chronic headaches and 1 patient with persistent idiopathic facial pain who were refractory to medical treatment. Thes...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1016/j.rapm.2006.03.011

    authors: Harris CL,Hamid B,Rosenquist RW,Schultz-Stubner SH

    更新日期:2006-09-01 00:00:00

  • Interscalene block with a nerve stimulator: a deltoid motor response is a satisfactory endpoint for successful block.

    abstract:BACKGROUND AND OBJECTIVES:The interscalene brachial plexus block (ISB) is an effective and well-established anesthetic technique for shoulder surgery. Using nerve stimulation as an aid in block placement, a motor response (twitch) in the biceps or a more distal upper limb muscle has been recommended to indicate accurat...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 临床试验,杂志文章

    doi:10.1053/rapm.2000.7597

    authors: Silverstein WB,Saiyed MU,Brown AR

    更新日期:2000-07-01 00:00:00

  • Two-pore domain potassium channels: new sites of local anesthetic action and toxicity.

    abstract::Potassium (K+) channels form the largest family of ion channels with more than 70 such genes identified in the human genome. They are organized in 3 superfamilies according to their predicted membrane topology: (1) subunits with 6 membrane-spanning segments and 1-pore domain, (2) subunits with 2 membrane-spanning segm...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.rapm.2004.12.001

    authors: Kindler CH,Yost CS

    更新日期:2005-05-01 00:00:00

  • Analgesia and anesthesia using the pericapsular nerve group block in hip surgery and hip fracture: a scoping review.

    abstract:INTRODUCTION:Pericapsular nerve group (PENG) block is a novel regional analgesia technique to reduce pain after hip surgery and hip fractures. This review was conducted to summarize current literature. METHODS:A scoping review was carried out using the Joanna Briggs Institute framework. All articles describing the use...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,评审

    doi:10.1136/rapm-2020-101826

    authors: Morrison C,Brown B,Lin DY,Jaarsma R,Kroon H

    更新日期:2021-02-01 00:00:00

  • Influence of spinal anesthesia on corrected QT interval.

    abstract:BACKGROUND AND OBJECTIVES:Prolongation of the QT interval may result in grave cardiac arrhythmias, polymorphic ventricular tachycardia ("torsades de pointes"), and ventricular fibrillation. We assessed the influence of spinal anesthesia on the QTc interval and the potential arrhythmogenicity of this method of anesthesi...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1016/j.rapm.2005.06.005

    authors: Owczuk R,Sawicka W,Wujtewicz MA,Kawecka A,Lasek J,Wujtewicz M

    更新日期:2005-11-01 00:00:00

  • Perioperative research fellowship: planning, implementation, experience.

    abstract::Perioperative outcomes research has gained widespread interest and is viewed as increasingly important among different specialties, including anesthesiology. Outcomes research studies serve to help in the adjustment of risk, allocation of resources, and formulation of hypotheses to guide future research. Pursuing high...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,评审

    doi:10.1097/AAP.0000000000000110

    authors: Memtsoudis SG,Mazumdar M,Stundner O,Hargett MJ

    更新日期:2014-09-01 00:00:00

  • Spread of Quadratus Lumborum Block to the Paravertebral Space Via Intramuscular Injection: A Volunteer Study.

    abstract:BACKGROUND AND OBJECTIVES:Several types of quadratus lumborum block (QLB) are used for postoperative analgesia and are believed to be effective against both somatic and visceral pain via a local anesthetic (LA) effect in the paravertebral space (PVS). However, it remains unclear whether all QLB techniques result in LA ...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1097/AAP.0000000000000735

    authors: Tamura T,Kitamura K,Yokota S,Ito S,Shibata Y,Nishiwaki K

    更新日期:2018-05-01 00:00:00

  • Neurologic Evaluation and Management of Perioperative Nerve Injury.

    abstract:UNLABELLED:Neurologic injury after regional anesthesia or pain medicine procedures is rare. Postprocedural neurologic deficits may create high levels of anxiety for the patient and practitioner, although most deficits are limited in severity and can be expected to fully resolve with time. Postoperative anesthesia-relat...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,评审

    doi:10.1097/AAP.0000000000000185

    authors: Watson JC,Huntoon MA

    更新日期:2015-09-01 00:00:00

  • Dislocation of a femur fracture after femoral nerve block.

    abstract:OBJECTIVE:Femoral nerve block (FNB) is increasingly used as an analgesic modality in patients with femoral fracture both in the emergency department and preoperatively. We describe an occurrence of unexpected dislocation of the fracture after FNB. CASE REPORT:An FNB was administered to treat pain in a 48-year-old pati...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1097/AAP.0000000000000049

    authors: Marić S,Robinson A,Vandepitte C,Hadzic A

    更新日期:2014-03-01 00:00:00

  • Effects of diluent volume of a single dose of epidural bupivacaine in parturients during the first stage of labor.

    abstract:BACKGROUND AND OBJECTIVES:0.1% bupivacaine for obstetric epidural analgesia is given by infusion, using a loading dose of a higher concentration alone or in combination with opioid analgesics. A single dose of 0.1% without any additive for relief of first-stage labor pain has not yet been documented. METHODS:Fifty-eig...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/00115550-199823020-00004

    authors: Christiaens F,Verborgh C,Dierick A,Camu F

    更新日期:1998-03-01 00:00:00

  • Objective assessment of manual skills and proficiency in performing epidural anesthesia--video-assisted validation.

    abstract:BACKGROUND AND OBJECTIVES:Demand is growing for objective assessment of manual skills and competencies of invasive procedures. The aim of this study was to validate an objective tool for assessing residents' skill in performing epidural anesthesia by use of a global assessment scale and a 3-scale, 27-stage checklist. W...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1016/j.rapm.2006.04.006

    authors: Friedman Z,Katznelson R,Devito I,Siddiqui M,Chan V

    更新日期:2006-07-01 00:00:00

  • Femoral block provides superior analgesia compared with intra-articular ropivacaine after anterior cruciate ligament reconstruction.

    abstract:BACKGROUND AND OBJECTIVES:Arthroscopic anterior cruciate ligament (ACL) reconstruction of the knee is a painful procedure requiring intensive postoperative pain management. This prospective study investigates analgesic quality after a femoral block as compared with intra-articular injection of local anesthetic. METHOD...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1053/rapm.2003.50019

    authors: Iskandar H,Benard A,Ruel-Raymond J,Cochard G,Manaud B

    更新日期:2003-01-01 00:00:00

  • Clinical trial methodology of pain treatment studies: selection and measurement of self-report primary outcomes for efficacy.

    abstract::The past century has seen immense progress in the advancement of methodology to evaluate efficacy of treatment interventions for acute and chronic pain. Continuing challenges revolve around how to best select and measure primary efficacy outcomes for a given analgesic trial. Recognizing the complex, multidimensional, ...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,评审

    doi:10.1097/AAP.0b013e318217a635

    authors: Gilron I,Jensen MP

    更新日期:2011-07-01 00:00:00

  • Intrathecal mepivacaine and prilocaine are less neurotoxic than lidocaine in a rat intrathecal model.

    abstract:BACKGROUND AND OBJECTIVES:Histologic evidence of the comparative neurotoxicity of lidocaine, mepivacaine, and prilocaine is incomplete. We compared the intrathecal neurotoxicity in rats among these 3 drugs based on morphologic and neurofunctional findings. METHODS:Rats (n=169) randomly received 0.12 microL/g of 0%, 2%...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1016/j.rapm.2004.06.013

    authors: Takenami T,Yagishita S,Nara Y,Hoka S

    更新日期:2004-09-01 00:00:00

  • Effects of head-up tilt after stellate ganglion block on QT interval and QT dispersion.

    abstract:BACKGROUND AND OBJECTIVES:The aim of this study is to examine the effects of head-up tilt (70 degrees ) 30 minutes after right or left stellate ganglion block (SGB) on RR interval, QT interval, the rate-corrected QT (QTc) interval, QT dispersion (QTD), and the rate-corrected QT dispersion (QTcD) using computerized meas...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1016/j.rapm.2004.03.009

    authors: Fujii K,Yamaguchi S,Egawa H,Hamaguchi S,Kitajima T,Minami J

    更新日期:2004-07-01 00:00:00

  • Epidural catheter placement in neonates: sonoanatomy and feasibility of ultrasonographic guidance in term and preterm neonates.

    abstract:BACKGROUND:We report the first prospective sonoanatomic study in neonates with the aim to perform ultrasonographic-guided epidural catheter placement in this age group. METHOD:One hundred forty-five neonates with a body weight < or =4 kg (0.53-4 kg) were included in this prospective study. The study was divided into 3...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1016/j.rapm.2006.10.008

    authors: Willschke H,Bosenberg A,Marhofer P,Willschke J,Schwindt J,Weintraud M,Kapral S,Kettner S

    更新日期:2007-01-01 00:00:00