Abstract:
BACKGROUND AND OBJECTIVES:This prospective randomized trial compared ultrasound-guided single-injection (SI) and triple-injection (TI) subparaneural popliteal sciatic nerve block. We hypothesized that multiple injections are not required when local anesthetic (LA) is deposited under the paraneurium because the latter entraps LA molecules, ensuring circumferential spread around the nerve. Therefore, in addition to comparable success rates, we also expected similar total anesthesia-related times (sum of performance and onset times) and designed this study as an equivalency trial. METHODS:Ultrasound-guided subparaneural posterior popliteal sciatic nerve block was carried out in 100 patients. In the SI group, LA was deposited at a single location between the tibial and peroneal nerves. In the TI group, LA was injected between the tibial and peroneal divisions, medial to the tibial nerve, and lateral to the common peroneal nerve. The total LA volume (15 mL) and mixture (lidocaine 1%-bupivacaine 0.25%-epinephrine 5 μg/mL) were identical in all subjects. The performance time, number of needle passes, and adverse events (paresthesia, neural edema) were recorded by the (nonblinded) investigator supervising the block. A blinded observer evaluated the success rate (sensorimotor composite score ≥6/8 points at 30 minutes) as well as the onset time and contacted patients 7 days after the surgery to inquire about persistent numbness or motor deficit. RESULTS:Both techniques provided comparable success rates (92%) and total anesthesia-related times (17.1-19.7 minutes). Expectedly, the SI group required fewer needle passes (1 vs 3; P < 0.001) and a shorter needling time (3.0 ± 2.3 minutes vs 4.0 ± 2.3 minutes; P = 0.025). The TI group displayed a shorter onset time (12.5 ± 7.9 minutes vs 15.8 ± 7.9 minutes; P = 0.027). The performance time, procedural discomfort, and incidence of paresthesia (14%-20%) were similar between the 2 groups. Sonographic neural swelling was detected in 2 subjects in the SI group. In both cases, the needle was carefully withdrawn and the injection was completed uneventfully. Follow-up of the 100 subjects 1 week after surgery revealed no residual numbness or motor deficit. CONCLUSIONS:Ultrasound-guided SI and TI subparaneural popliteal sciatic nerve blocks result in comparable success rates and total anesthesia-related times. Expectedly, the SI technique requires fewer needle passes.
journal_name
Reg Anesth Pain Medjournal_title
Regional anesthesia and pain medicineauthors
Tiyaprasertkul W,Bernucci F,González AP,Leurcharusmee P,Yazer MS,Techasuk W,Arnuntasupakul V,de la Garza DC,Finlayson RJ,Tran DQdoi
10.1097/AAP.0000000000000253subject
Has Abstractpub_date
2015-07-01 00:00:00pages
315-20issue
4eissn
1098-7339issn
1532-8651journal_volume
40pub_type
杂志文章,多中心研究,随机对照试验abstract:BACKGROUND AND OBJECTIVES:A variety of brachial plexus block techniques via the interscalene approach have been proposed. We describe here a new middle interscalene perivascular approach to the brachial plexus. To verify its effectiveness, we studied 719 patients scheduled for shoulder arthroscopy. Furthermore, to veri...
journal_title:Regional anesthesia and pain medicine
pub_type: 临床试验,杂志文章
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更新日期:2006-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Practitioners mix faster-onset, intermediate-duration local anesthetics (LAs) with slower-onset, long-duration LAs to get fast peripheral nerve block (PNB) onset and long duration. We hypothesized that 1.5% mepivacaine (with epinephrine) (mepivacaine) or 1.5% mepivacaine (with epinephrine) mix...
journal_title:Regional anesthesia and pain medicine
pub_type: 杂志文章,随机对照试验
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journal_title:Regional anesthesia and pain medicine
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Regional anesthesia and pain medicine
pub_type: 杂志文章,meta分析
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journal_title:Regional anesthesia and pain medicine
pub_type: 杂志文章,随机对照试验
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journal_title:Regional anesthesia and pain medicine
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Regional anesthesia and pain medicine
pub_type: 临床试验,杂志文章
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journal_title:Regional anesthesia and pain medicine
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journal_title:Regional anesthesia and pain medicine
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journal_title:Regional anesthesia and pain medicine
pub_type: 杂志文章
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journal_title:Regional anesthesia and pain medicine
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2000-11-01 00:00:00
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journal_title:Regional anesthesia and pain medicine
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journal_title:Regional anesthesia and pain medicine
pub_type: 杂志文章
doi:10.1016/j.rapm.2005.09.004
更新日期:2006-01-01 00:00:00
abstract::Potassium (K+) channels form the largest family of ion channels with more than 70 such genes identified in the human genome. They are organized in 3 superfamilies according to their predicted membrane topology: (1) subunits with 6 membrane-spanning segments and 1-pore domain, (2) subunits with 2 membrane-spanning segm...
journal_title:Regional anesthesia and pain medicine
pub_type: 杂志文章,评审
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journal_title:Regional anesthesia and pain medicine
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Regional anesthesia and pain medicine
pub_type: 杂志文章
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pub_type: 杂志文章,多中心研究
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journal_title:Regional anesthesia and pain medicine
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Regional anesthesia and pain medicine
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journal_title:Regional anesthesia and pain medicine
pub_type: 杂志文章,评审
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更新日期:2018-01-01 00:00:00
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journal_title:Regional anesthesia and pain medicine
pub_type: 杂志文章
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更新日期:2008-11-01 00:00:00
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journal_title:Regional anesthesia and pain medicine
pub_type: 杂志文章
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更新日期:2015-11-01 00:00:00
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journal_title:Regional anesthesia and pain medicine
pub_type: 杂志文章,实务指引
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更新日期:2015-05-01 00:00:00
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journal_title:Regional anesthesia and pain medicine
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journal_title:Regional anesthesia and pain medicine
pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
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