Abstract:
OBJECTIVES:To determine whether patient age is associated with differences in flexible bronchoscopy technique and tolerance. DESIGN:Prospective cohort study. SETTING:University hospital system. PARTICIPANTS:One thousand three hundred fifty-eight adults, including 219 (16.1%) aged 70 and older, undergoing bronchoscopy. MEASUREMENTS:Indications, sampling procedures, medication doses, patient reports of pain, willingness to return, and adverse events associated with bronchoscopy. RESULTS:Indications for bronchoscopy varied with age, with solitary pulmonary nodule (P <.001), mass (P <.001), or lymphadenopathy (P <.001) being more common in older patients. Invasive sampling methods were used more often with increasing age, but variation in disease processes between age groups accounted for the difference in sampling method performed. Mean doses of midazolam and fentanyl given for sedation decreased with increasing age (P <.001). There was no significant difference between older and younger patients in reported very good to excellent pain control (50% of patients >/=70 vs 64% of patients <40; P =.56) or in willingness to return for repeat bronchoscopy (98% vs 92%, respectively; P =.324). Overall risk for an adverse event increased with increasing patient age (P <.01), but adverse events were uncommon and generally not severe. Hypotension and pneumothorax were rare but occurred more often in older persons (1.9% and 3.4% in patients >/=70 vs 0.5% and 0.7% in patients <40, respectively). CONCLUSION:Despite more-invasive sampling methods and less sedation during bronchoscopy, elderly patients tolerate bronchoscopy as well as younger patients. There is increased risk for adverse events with increasing age, but the absolute frequency is low, suggesting that chronological age should not be a contraindication for bronchoscopy in older persons.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Hehn BT,Haponik E,Rubin HR,Lechtzin N,Diette GBdoi
10.1046/j.1365-2389.2003.51303.xsubject
Has Abstractpub_date
2003-07-01 00:00:00pages
917-22issue
7eissn
0002-8614issn
1532-5415journal_volume
51pub_type
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journal_title:Journal of the American Geriatrics Society
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doi:10.1111/j.1532-5415.1990.tb03539.x
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abstract::Recurrent Clostridium difficile infection (CDI) is a common nosocomial infection that has a large effect on morbidity and quality of life in older adults in hospitals and long-term care facilities. Because antibiotics are often unsuccessful in curing this disease, fecal transplantation has emerged as a second-line the...
journal_title:Journal of the American Geriatrics Society
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15702
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1992.tb03648.x
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
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更新日期:2011-11-01 00:00:00
abstract::Absorption of folates, vitamin B6, pantothenate, and riboflavin from a natural food source (yeast) and from synthetic folylmonoglutamate was studied in 24 elderly subjects (age range, 73 to 101 years) and in 12 healthy younger subjects (age range, 24 to 42 years). All subjects absorbed riboflavin, vitamin B6, and pant...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
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abstract:OBJECTIVES:To investigate the association between blood pressure and mortality in very old people. DESIGN:Population-based cohort study. SETTING:County of Västerbotten, Sweden. PARTICIPANTS:Half of all subjects aged 85 and all of those aged 90 and 95 and older (N=348) in one urban and five rural municipalities in th...
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doi:10.1111/j.1532-5415.2008.01948.x
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,meta分析,评审
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2003.51556.x
更新日期:2003-12-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/jgs.13922
更新日期:2016-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/jgs.16343
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journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章
doi:10.1046/j.1532-5415.2001.49117.x
更新日期:2001-05-01 00:00:00
abstract:OBJECTIVES:To assess the relative independent contribution of changes in executive control function (ECF) and memory to changes in functional status. DESIGN:Three-year longitudinal cohort study. SETTING:A comprehensive care retirement community. PARTICIPANTS:Five hundred forty-seven noninstitutionalized people aged ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2005.53004.x
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Mammographic screening for breast cancer is of uncertain clinical benefit for women 75 years of age and older. Some have argued against instituting routine screening in this age group, noting that disability and shorter life expectancy may diminish the desirability and cost-effectiveness of sc...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1998.tb02746.x
更新日期:1998-08-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1977.tb00665.x
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journal_title:Journal of the American Geriatrics Society
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doi:10.1111/j.1532-5415.1976.tb03314.x
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15931
更新日期:2019-07-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16452
更新日期:2020-08-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1996.tb03729.x
更新日期:1996-07-01 00:00:00
abstract:OBJECTIVES:To evaluate the effectiveness of pelvic floor muscle (PFM) and fitness exercises in reducing urine leakage in elderly women with stress urinary incontinence (UI). DESIGN:Randomized, crossover, follow-up trial. SETTING:Urban community in Japan. PARTICIPANTS:Seventy women aged 70 and older who reported urin...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2007.01447.x
更新日期:2007-12-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2004.52352.x
更新日期:2004-08-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03576.x
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVES:To explore associations between serum 25-hydroxyvitamin D (25(OH)D) levels and a wide range of health conditions, physical performance measures, disability, and mortality in a large epidemiological study to identify an optimum range for 25(OH)D concentrations. DESIGN:Cross-sectional study, with additional p...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12693
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVES:To identify specific care management activities within a dementia care management intervention that are associated with 18-month change in caregiver mastery and relationship strain. DESIGN:Exploratory analysis, using secondary data (care management processes and caregiver outcomes) from the intervention arm...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1532-5415.2008.01643.x
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVES:To examine the relationship between baseline hypertension, blood pressure, and the development of cognitive decline in participants in the Women's Health Initiative Memory Study (WHIMS). DESIGN:Prospective analyses. SETTING:Thirty-nine centers. PARTICIPANTS:Seven thousand one hundred forty-nine women aged...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1532-5415.2008.01806.x
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVES:To evaluate the association between insulin resistance (IR) and executive dysfunction in a large, population-based study of older persons without diabetes mellitus (DM) or dementia. DESIGN:Cross-sectional study. SETTING:Outpatient clinic in Greve in Chianti and Bagno a Ripoli, Italy. PARTICIPANTS:A total ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2004.52466.x
更新日期:2004-10-01 00:00:00