Issues in clinical trials with the depressed elderly.

Abstract:

:Despite the fact that there is a high prevalence of depression among the elderly, little research on the efficacy of psychotherapy or pharmacotherapy with the elderly has been reported in the literature. This paper describes a sample of 18 elderly patients who received both psychotherapy and pharmacotherapy for the treatment of depression. Psychotherapy involved weekly 30-50 minutes sessions of interpersonal psychotherapy with a treating psychiatrist. The drug treatment consisted of random assignment, double-blind, to either alprazolam, imipramine, or pill-placebo for six weeks. The focus of therapy was on the attendance, compliance, and symptomatic relief in elderly depressed patients, as well as on the major life problems identified by these patients in psychotherapy. Results indicated that elderly patients respond to community publicity regarding a psychotherapy treatment program. However, the majority are inappropriate referrals for diagnostic reasons. If accepted, elderly patients showed good compliance with drugs, and attendance was comparable to that in younger populations. The elderly patients responded well to treatment, with immediate and marked improvement on the Hamilton and Raskin Depression Scales, which was maintained after treatment. Grief and role transitions specific to life changes were frequent antecedents to depression in this elderly population and thus were the major foci in psychotherapy.

journal_name

J Am Geriatr Soc

authors

Rothblum ED,Sholomskas AJ,Berry C,Prusoff BA

doi

10.1111/j.1532-5415.1982.tb01982.x

subject

Has Abstract

pub_date

1982-11-01 00:00:00

pages

694-9

issue

11

eissn

0002-8614

issn

1532-5415

journal_volume

30

pub_type

临床试验,杂志文章,随机对照试验
  • Evaluating patients' warfarin requirements.

    abstract::Seventy consecutive patients receiving warfarin as an anticoagulant were evaluated for the relationship between the response to the loading dose of warfarin and the response to the maintenance dose. No patients were excluded because of complicating diseases or the concurrent use of other drugs. There was a moderate co...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1980.tb00116.x

    authors: Jones BR,Baran A,Reidenberg MM

    更新日期:1980-01-01 00:00:00

  • Are Alzheimer patients healthier?

    abstract::At an active outpatient geriatric program the gerontological team observed that Alzheimer patients appear to have fewer physical ailments than other elderly patients. To test this hypothesis, we reviewed a sample of 348 clinic patients. One hundred forty-three had a normal mental status; 75 had Alzheimer's disease as ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1988.tb01804.x

    authors: Wolf-Klein GP,Siverstone FA,Brod MS,Levy A,Foley CJ,Termotto V,Breuer J

    更新日期:1988-03-01 00:00:00

  • Effect of physical activity guidelines on physical function in older adults.

    abstract:OBJECTIVES:To determine whether elderly people who meet national guidelines have higher physical function (PF) scores than those who do not and the effect on functional trajectory when physical activity (PA) levels change from above to below this threshold, or vice versa. DESIGN:Pooled data. SETTING:Two 6-month rando...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1532-5415.2008.01937.x

    authors: Morey MC,Sloane R,Pieper CF,Peterson MJ,Pearson MP,Ekelund CC,Crowley GM,Demark-Wahnefried W,Snyder DC,Clipp EC,Cohen HJ

    更新日期:2008-10-01 00:00:00

  • Dementia family caregiver training: affecting beliefs about caregiving and caregiver outcomes.

    abstract:OBJECTIVES:Family caregiving is an integral part of the care system for persons with dementing disorders, such as Alzheimer's disease. This study tested role-training intervention as a way to help family caregivers appreciate and assume a more clinical belief set about caregiving and thereby ameliorate the adverse outc...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1532-5415.2001.49090.x

    authors: Hepburn KW,Tornatore J,Center B,Ostwald SW

    更新日期:2001-04-01 00:00:00

  • Underdiagnosis of Influenza Virus Infection in Hospitalized Older Adults.

    abstract:OBJECTIVES:To describe factors associated with provider-ordered influenza testing in hospitalized older adults. DESIGN:Information on participant demographics, symptoms, and provider-ordered influenza testing were collected by questionnaire and chart review. We conducted prospective laboratory-based surveillance using...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.15298

    authors: Hartman L,Zhu Y,Edwards KM,Griffin MR,Talbot HK

    更新日期:2018-03-01 00:00:00

  • Perspectives of Patients in Identifying Their Values-Based Health Priorities.

    abstract:OBJECTIVES:Patient Health Priorities Identification (PHPI) is a values-based process in which trained facilitators assist older adults with multiple chronic conditions identify their health priorities. The purpose of this study was to evaluate patients' perceptions of PHPI. DESIGN:Qualitative study using thematic anal...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.15850

    authors: Feder SL,Kiwak E,Costello D,Dindo L,Hernandez-Bigos K,Vo L,Geda M,Blaum C,Tinetti ME,Naik AD

    更新日期:2019-07-01 00:00:00

  • Use of self-report to predict ability to walk 400 meters in mobility-limited older adults.

    abstract:OBJECTIVES:To determine whether the ability to walk 400 m could be predicted from self-reported walking habits and abilities in older adults and to develop an accurate self-report measure appropriate for observational trials of mobility when functional measures are impractical to collect. DESIGN:Cross-sectional. SETT...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2004.52571.x

    authors: Sayers SP,Brach JS,Newman AB,Heeren TC,Guralnik JM,Fielding RA

    更新日期:2004-12-01 00:00:00

  • Lower systolic blood pressure is associated with greater mortality in people aged 85 and older.

    abstract:OBJECTIVES:To investigate the association between blood pressure and mortality in very old people. DESIGN:Population-based cohort study. SETTING:County of Västerbotten, Sweden. PARTICIPANTS:Half of all subjects aged 85 and all of those aged 90 and 95 and older (N=348) in one urban and five rural municipalities in th...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2008.01948.x

    authors: Molander L,Lövheim H,Norman T,Nordström P,Gustafson Y

    更新日期:2008-10-01 00:00:00

  • Thyroid disease in the elderly.

    abstract::Thyroid disease in the aged, both hypothyroidism and hyperthyroidism, may be subtle or may be present with no clinical symptoms and signs, and is therefore difficult to diagnose on the basis of clinical evaluation. The help of the laboratory is essential in making the diagnosis of disease of the thyroid. Therapeutic s...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,评审

    doi:10.1111/j.1532-5415.1993.tb06488.x

    authors: Mokshagundam S,Barzel US

    更新日期:1993-12-01 00:00:00

  • Associations of physical activity with performance-based and self-reported physical functioning in older men: the Honolulu Heart Program.

    abstract:OBJECTIVE:To examine the association of self-reported physical activity with performance-based and self-reported physical functioning measured 3 to 5 years later. DESIGN:A population-based, longitudinal study. SETTING:The island of Oahu, Hawaii. PARTICIPANTS:Subjects were 3640 Japanese-American men older than 70 yea...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1995.tb05525.x

    authors: Young DR,Masaki KH,Curb JD

    更新日期:1995-08-01 00:00:00

  • Falls in the institutionalized elderly.

    abstract::The reports on 72 of 190 accidents occurring among 189 nursing home residents during a 3-month period were drawn at random and reviewed. The majority of the accidents were falls, either major or minor. Personal data on the residents included age, sex, mental status, number of diseases, and number of drugs administered...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1978.tb05391.x

    authors: Kalchthaler T,Bascon RA,Quintos V

    更新日期:1978-09-01 00:00:00

  • Improving the quality of life for the elderly.

    abstract::The United States Senator from Maryland, as speaker at the Awards luncheon of the American Geriatrics Society (Washington meeting), presented his views on priorities in various health programs for the elderly, and asked for the Society's cooperation in making some of the difficult decisions that lie ahead. An importan...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1979.tb01672.x

    authors: Mathias CM Jr

    更新日期:1979-09-01 00:00:00

  • Racial and ethnic differences in the mental health needs and access to care of older adults in california.

    abstract::Little is known about the unmet mental health needs of minority older adults. Racial and ethnic differences in the prevalence rates of psychological distress and reported need and use of mental health services were examined in a population-based sample of older adults using the 2005 California Health Interview Survey....

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2009.02573.x

    authors: Sorkin DH,Pham E,Ngo-Metzger Q

    更新日期:2009-12-01 00:00:00

  • Multimorbidity and Risk of Mild Cognitive Impairment.

    abstract:OBJECTIVES:To determine the association between multiple chronic conditions and risk of incident mild cognitive impairment (MCI) and dementia. DESIGN:Prospective cohort study. SETTING:Olmsted County, Minnesota. PARTICIPANTS:Cognitively normal individuals (N = 2,176) enrolled in the Mayo Clinic Study of Aging (MCSA)....

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.13612

    authors: Vassilaki M,Aakre JA,Cha RH,Kremers WK,St Sauver JL,Mielke MM,Geda YE,Machulda MM,Knopman DS,Petersen RC,Roberts RO

    更新日期:2015-09-01 00:00:00

  • Disease severity and health-related quality of life across different chronic conditions.

    abstract:OBJECTIVES:Measurements of health-related quality of life (HRQL) are an essential component in overall assessment of health status, particularly in older patients. Nevertheless, how measures of HRQL relate to measures of disease severity is largely unexplored. This study was carried out to explore the relationship betw...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:

    authors: Ferrucci L,Baldasseroni S,Bandinelli S,de Alfieri W,Cartei A,Calvani D,Baldini A,Masotti G,Marchionni N

    更新日期:2000-11-01 00:00:00

  • Leukocyte telomere length is associated with disability in older u.s. Population.

    abstract:OBJECTIVES:To determine whether mean leukocyte telomere length (LTL) serves as a biomarker of disability assessed according to activities of daily living (ADLs) and what factors may modify this relationship. DESIGN:Retrospective cross-sectional study. SETTING:A subset of the National Long Term Care Survey (NTLCS), a ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2010.02948.x

    authors: Risques RA,Arbeev KG,Yashin AI,Ukraintseva SV,Martin GM,Rabinovitch PS,Oshima J

    更新日期:2010-07-01 00:00:00

  • Withholding versus withdrawing life-sustaining treatment: patient factors and documentation associated with dialysis decisions.

    abstract:OBJECTIVE:We evaluated prospectively the use of acute hemodialysis among hospitalized patients to identify demographic and clinical predictors of and chart documentation concerning dialysis withheld and withdrawn. DESIGN:Prospective cohort study. SETTING:Five teaching hospitals. PATIENTS:Five hundred sixty-five seri...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/j.1532-5415.2000.tb03145.x

    authors: Wenger NS,Lynn J,Oye RK,Liu H,Teno JM,Phillips RS,Desbiens NA,Sehgal A,Kussin P,Taub H,Harrell F,Knaus W

    更新日期:2000-05-01 00:00:00

  • Hallucinations of widowhood.

    abstract::Widowed residents of two nursing homes who were oriented to person, time, and place were interviewed to determine the extent to which they had hallucinatory experiences of their deceased spouse. Fifty-two interviews were completed with 46 widows and six widowers. Results are reported for the widows. Twenty-eight (61%)...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1985.tb04619.x

    authors: Olson PR,Suddeth JA,Peterson PJ,Egelhoff C

    更新日期:1985-08-01 00:00:00

  • Screening for cognitive impairment in an elderly veteran population: acceptability and results using different versions of the Mini-Cog.

    abstract:OBJECTIVES:To assess the feasibility of cognitive screening in older veterans presenting for routine primary care. DESIGN:Quality improvement initiative. SETTING:Seven Veterans Affairs Medical Centers. PARTICIPANTS:Veterans aged 70 and older without a prior diagnosis of cognitive impairment. MEASUREMENTS:Scores fro...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1532-5415.2010.03249.x

    authors: McCarten JR,Anderson P,Kuskowski MA,McPherson SE,Borson S

    更新日期:2011-02-01 00:00:00

  • Circumstances and contributing causes of fall deaths among persons aged 65 and older: United States, 2010.

    abstract:OBJECTIVES:To determine whether the increasing fall death rate among people aged 65 and older is due in part to temporal changes in recording the underlying cause of death. DESIGN:Analyses of multiple cause of death data using the online Centers for Disease Control and Prevention Wide-ranging ON-line Data for Epidemio...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.12702

    authors: Stevens JA,Rudd RA

    更新日期:2014-03-01 00:00:00

  • Lower body functioning prevalence and correlates in older American Indians in a southeastern tribe: the Native Elder Care Study.

    abstract::The objective of this study was to use performance-based measurements to identify, in a population of community-dwelling American Indians aged 55 and older, the prevalence and correlates of lower body functioning. Data were collected as part of a cross-sectional study of disability from members of a tribe in the south...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2011.03869.x

    authors: Goins RT,Innes K,Dong L

    更新日期:2012-03-01 00:00:00

  • Modeling cognitive trajectories within longitudinal studies: a focus on older adults.

    abstract::The natural history of life span cognitive performance and its late-life determinants have been studied from an array of perspectives. Significant insights come from psychological disciplines, including cognitive, developmental, and neuropsychology, as well as from medical specialties, such as geriatrics, neurology, p...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,评审

    doi:10.1111/j.1532-5415.2010.02982.x

    authors: Steinerman JR,Hall CB,Sliwinski MJ,Lipton RB

    更新日期:2010-10-01 00:00:00

  • Use of urinary collection devices in skilled nursing facilities in five states.

    abstract:OBJECTIVES:To assess use of urinary collection devices (external, intermittent, and indwelling catheters; pads or briefs) and examine predictors of indwelling catheters in skilled nursing facilities (SNFs). DESIGN:Retrospective cohort study. SETTING:SNFs in California, Florida, Michigan, New York, and Texas. PARTICI...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2008.01675.x

    authors: Rogers MA,Mody L,Kaufman SR,Fries BE,McMahon LF Jr,Saint S

    更新日期:2008-05-01 00:00:00

  • An analysis of the use of the telephone in the management of patients in skilled nursing facilities.

    abstract:OBJECTIVE:To characterize the nature of telephone communication in the care of patients in skilled nursing facilities, noting numbers of calls, reasons for communication, and the outcomes of the interactions, and to implement a voice mail system to manage the burden of communication more effectively and describe the im...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1997.tb00980.x

    authors: Fowkes W,Christenson D,McKay D

    更新日期:1997-01-01 00:00:00

  • Pyrazolopyridine derivative acts as a novel cyclooxygenase inhibitor: antiplatelet effect in aged patients with ischemic stroke.

    abstract:OBJECTIVE:To examine the antiplatelet effect of a novel pyrazolopyridine derivative (KC-764) in geriatric patients with ischemic stroke. DESIGN:Randomized clinical trial of three graded dose levels. SETTING:A geriatric clinic attached to a nursing home. PATIENTS:Fifteen patients with a history of cerebral infarction...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1532-5415.1994.tb06863.x

    authors: Satoh K,Yoshida H,Imaizumi TA,Koyama M,Hiramoto M,Takamatsu S

    更新日期:1994-06-01 00:00:00

  • Permanent cardiac pacemakers in the elderly.

    abstract:OBJECTIVE:To review (1) Changes in cardiac impulse generation, conduction, and ventricular filling in normal aging and disease; (2) Pacemaker technology and nomenclature; (3) Expert guidelines about pacemaker use; (4) Studies of pacemaker effectiveness and utilization. DESIGN:Articles were identified through a Medline...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,评审

    doi:10.1111/j.1532-5415.1994.tb01760.x

    authors: Bush DE,Finucane TE

    更新日期:1994-03-01 00:00:00

  • Factors noted to affect breast cancer treatment decisions of women aged 80 and older.

    abstract:OBJECTIVES:To identify factors that influence the breast cancer treatment decisions of women aged 80 and older. DESIGN:Medical record review. SETTING:One academic primary care clinic and two community health centers in Boston. PARTICIPANTS:Sixty-five women aged 80 and older diagnosed with breast cancer between 1994 ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2011.03820.x

    authors: Schonberg MA,Silliman RA,McCarthy EP,Marcantonio ER

    更新日期:2012-03-01 00:00:00

  • Influenza outbreak detection and control measures in nursing homes in the United States.

    abstract:OBJECTIVE:To evaluate the use of influenza vaccine, rapid influenza testing, and influenza antiviral medication in nursing homes in the US to prevent and control outbreaks. METHODS:Survey questionnaires were sent to 1017 randomly selected nursing homes in nine states. Information was collected on influenza prevention,...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2000.tb02606.x

    authors: Zadeh MM,Buxton Bridges C,Thompson WW,Arden NH,Fukuda K

    更新日期:2000-10-01 00:00:00

  • Diagnosis and management of urinary tract infection in hospitalized older people.

    abstract:OBJECTIVES:To compare the diagnosis and management of urinary tract infection (UTI) in hospitalized older people with clinical criteria and therapeutic guidelines. DESIGN:A retrospective case series of emergency hospital admissions collected over an 18-month period. SETTING:An acute general hospital in northwest Engl...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2008.02073.x

    authors: Woodford HJ,George J

    更新日期:2009-01-01 00:00:00

  • No old man ever forgot where he buried his treasure: concepts of cognitive impairment in old age circa 1700.

    abstract::Cognitive impairment in old age is one of the most important topics in modern geriatrics. This article discusses the historical dimensions of this phenomenon. To this end, a number of primary sources ranging from antiquity to the modern era are evaluated. Although a physiology and pathology of old age were conceptuali...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 历史文章,杂志文章

    doi:10.1111/j.1532-5415.2005.53558.x

    authors: Schäfer D

    更新日期:2005-11-01 00:00:00