Abstract：
OBJECTIVES:Measurements of health-related quality of life (HRQL) are an essential component in overall assessment of health status, particularly in older patients. Nevertheless, how measures of HRQL relate to measures of disease severity is largely unexplored. This study was carried out to explore the relationship between a measure of HRQL and measures of severity of ischemic stroke, Parkinson's diseases (PD), or chronic coronary heart disease (CHD). DESIGN AND SETTING:Cross-sectional analysis of three groups (54 subjects each) of patients aged > or = 65 years consecutively referred to outpatient clinics for stroke, PD, or CHD, excluding those with cognitive impairment and severe comorbidity. MEASUREMENTS:Severity of stroke, PD, and CHD assessed by Fugl-Meyer Scale (FMS), Webster Rating Scale (WBRS), and total work capacity (TWC, from graded exercise test), respectively. HRQL was determined by the Sickness Impact Profile (SIP). RESULTS:In PD, WBRS correlated linearly with SIP global score, whereas a significant linear relationship between measures of disease severity and SIP score was limited to the least severely diseased stroke (FMS score>160) and the most severely diseased CHD (TWC <700 Kg x m) patients. CONCLUSIONS:In some disease, the relationship between clinical measures of disease severity and HRQL is nonlinear. Thus, depending on initial severity, similar changes in disease severity may have different impacts on HRQL. These findings may help in identifying patients most likely to improve their SIP score substantially, after even small changes in disease severity. However, studies examining the metric properties of SIP across the whole score range are needed to verify whether such improvement really translates into a better HRQL.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Ferrucci L,Baldasseroni S,Bandinelli S,de Alfieri W,Cartei A,Calvani D,Baldini A,Masotti G,Marchionni Nsubject
Has Abstractpub_date
2000-11-01 00:00:00pages
1490-5issue
11eissn
0002-8614issn
1532-5415journal_volume
48pub_type
杂志文章abstract：OBJECTIVES:To identify patient factors that influence physicians' decisions to recommend screening mammograms for older women. DESIGN:A cross-sectional survey including clinical case vignettes. PARTICIPANTS:Random sample of Massachusetts internists, obstetrician/gynecologists, family/general practice physicians, and ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1996.tb01371.x
更新日期：1996-10-01 00:00:00
abstract：:Thirty-two patients entered a simple-blind, cross-over study on the action of tocopherol in osteoarthritis; only 3 did not complete the course. Each patient was randomly assigned either to the tocopherol group (600 mg/day for 10 days) or to the placebo group. After 10 days the groups were transposed. The analgesic and...
journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1532-5415.1978.tb01345.x
更新日期：1978-07-01 00:00:00
abstract：OBJECTIVES:A common assumption is that life-sustaining treatments are much less cost-effective for older patients than for younger patients. We estimated the incremental cost-effectiveness of providing mechanical ventilation and intensive care for patients of various ages who had acute respiratory failure. DESIGN:Retr...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1046/j.1532-5415.2001.49080.x
更新日期：2001-04-01 00:00:00
abstract：OBJECTIVES:To evaluate the association between insulin resistance (IR) and executive dysfunction in a large, population-based study of older persons without diabetes mellitus (DM) or dementia. DESIGN:Cross-sectional study. SETTING:Outpatient clinic in Greve in Chianti and Bagno a Ripoli, Italy. PARTICIPANTS:A total ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2004.52466.x
更新日期：2004-10-01 00:00:00
abstract：OBJECTIVES:To assess the utility of verbal fluency discrepancy scores in predicting progression to Alzheimer's disease (AD) in a cohort of individuals with mild cognitive impairment (MCI). DESIGN:Case control. SETTING:Cases identified from new referrals to a memory clinic and controls identified from The Irish Longit...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15294
更新日期：2018-04-01 00:00:00
abstract：OBJECTIVES:To cross-sectionally quantify the contribution of proxy measures of cognitive reserve reflective of the lifespan, such as education, socioeconomic status (SES), reading ability, and cognitive activities, in explaining late-life cognition. DESIGN:Prospective observational cohort study of aging. SETTING:Reti...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2011.03499.x
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVE:To provide a critical evaluation of studies examining the contribution of changes in language-specific cognitive abilities to the speech perception difficulties of older adults. DESIGN:A review of the literature on aging and speech perception. CONCLUSIONS:The research considered in the present review sugges...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.1997.tb03101.x
更新日期：1997-05-01 00:00:00
abstract：:A study was made of 50 patients drawn at random from a Skilled Nursing Facility (SNF) attended by seven physicians. For 59 percent of these patients, polypharmacy was practiced but no substantiating diagnoses were recorded. Approximately half of the drugs were administered pro re nata. More drugs were prescribed in po...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1979.tb04139.x
更新日期：1979-03-01 00:00:00
abstract：OBJECTIVES:Gastrointestinal (GI) complications are the most-common serious adverse reactions associated with nonsteroidal anti-inflammatory drugs (NSAIDs). We quantified the effect of specific NSAIDs on the rate of GI hospitalizations among older people living in long-term care. DESIGN:Retrospective cohort study. SET...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1046/j.1532-5415.2001.49117.x
更新日期：2001-05-01 00:00:00
abstract：OBJECTIVES:To clarify the association between cholesterol and noncardiovascular mortality and to evaluate how this association varies across age groups. DESIGN:Prospective population-based cohort study. SETTING:Rotterdam, the Netherlands. PARTICIPANTS:Adults aged 55 to 99 (N = 5,750). MEASUREMENTS:Participants were...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2011.03593.x
更新日期：2011-10-01 00:00:00
abstract：:As nursing homes become increasingly important sites for biomedical and behavioral research, researchers must address the ethical problems of increased vulnerability and the high prevalence of mental and physical disorders in the nursing home population. Obtaining valid informed consent is but one of the many difficul...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.1993.tb07470.x
更新日期：1993-07-01 00:00:00
abstract：OBJECTIVES:To determine whether elderly people who meet national guidelines have higher physical function (PF) scores than those who do not and the effect on functional trajectory when physical activity (PA) levels change from above to below this threshold, or vice versa. DESIGN:Pooled data. SETTING:Two 6-month rando...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1532-5415.2008.01937.x
更新日期：2008-10-01 00:00:00
abstract：:The effect of do-not-resuscitate (DNR) orders on physicians' decisions to provide life-prolonging treatments other than cardiopulmonary resuscitation (CPR) for patients near the end of life was explored using a cross-sectional mailed survey. Each survey presented three patient scenarios followed by 10 treatment decisi...
journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1046/j.1532-5415.2002.50620.x
更新日期：2002-12-01 00:00:00
abstract：OBJECTIVES:To examine the combined influence of alcohol use and comorbidity on 20-year mortality in older adults (average age 66 at the time of the baseline survey). DESIGN:Longitudinal analysis of a national probability sample-based cohort study. SETTING:Data sources were the National Health and Nutrition Examinatio...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2006.00728.x
更新日期：2006-05-01 00:00:00
abstract：:In this paper, we present the consensus statement from a national conference on research priorities and methodologies for studying geriatric evaluation and management (GEM) programs. These conclusions, discussion points, and recommendations resulted from discussions of plenary papers, working group deliberations, and ...
journal_title：Journal of the American Geriatrics Society
pub_type： 共识发展会议,杂志文章,评审
doi：10.1111/j.1532-5415.1991.tb05936.x
更新日期：1991-09-01 00:00:00
abstract：OBJECTIVES:To map the extent, range, and nature of research on the effectiveness, level of use, and perceptions about electronic medication administration records (eMARs) in long-term care facilities (LTCFs) and identify gaps in current knowledge and priority areas for future research. DESIGN:Scoping review of quantit...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/jgs.15384
更新日期：2018-07-01 00:00:00
abstract：:Investigations of the natural history of blood pressure have generally evaluated mean systolic and diastolic pressure changes. While information, this information is not directly applicable to clinical practice settings, in which patients are usually classified as normotensive or hypertensive. We measured the actual i...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1989.tb02267.x
更新日期：1989-09-01 00:00:00
abstract：:To better understand declining autopsy rates, data have been gathered prospectively on 1080 consecutive deaths over six years among patients admitted to a medical intensive care/coronary care unit. Overall autopsy rate was 36%. Autopsy rates declined sharply with age from 60% for those aged 16 to 34 years to 23% for t...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1986.tb07260.x
更新日期：1986-12-01 00:00:00
abstract：:Previous studies have identified postprandial systolic blood pressure reductions in old, frail institutionalized subjects, which do not occur in healthy, young subjects, after a morning meal. To evaluate the relative contributions of state of health and time of day to this potentially dangerous abnormality in cardiova...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1986.tb04222.x
更新日期：1986-04-01 00:00:00
abstract：:The restructuring of The Medical Service at the Weill/Cornell campus of the New York Presbyterian Hospital, coupled with funding from the Donald W. Reynolds Foundation to strengthen physicians' training in geriatrics, enabled the creation of a geriatrics inpatient team and a 17-bed Acute Care for Elders unit. It has a...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2005.53122.x
更新日期：2005-02-01 00:00:00
abstract：OBJECTIVES:To investigate whether plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) remains a specific marker of cardiac illness in very old age and can be used to identify very elderly people at high risk for death independent of the presence of known cardiac diagnoses. DESIGN:Prospective, observational, po...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2009.02218.x
更新日期：2009-05-01 00:00:00
abstract：OBJECTIVE:To investigate whether a marked decrease in postprandial systolic blood pressure correlates with a higher incidence of falls, syncope, new coronary events, new stroke, and total mortality at long-term follow-up in older nursing home residents. DESIGN:In a prospective study of 499 nursing home residents aged ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1997.tb05965.x
更新日期：1997-09-01 00:00:00
abstract：OBJECTIVES:To compare the longitudinal changes in maximal aerobic capacity (VO2max) in healthy middle aged and older athletes and sedentary men. DESIGN:A cohort study with mean follow-up of 8.7 years (range 4.0-12.8). SETTING:Outpatient research at a tertiary hospital. PARTICIPANTS:Forty-two healthy, middle aged, an...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1046/j.1532-5415.2001.t01-1-49276.x
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVES:To assess what screening practices agencies use in hiring caregivers and how caregiver competency is measured before assigning responsibilities in caring for older adults. DESIGN:One-to-one phone interviews in which interviewers posed as prospective clients seeking a caregiver for an older adult relative. ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1532-5415.2012.04047.x
更新日期：2012-07-01 00:00:00
abstract：OBJECTIVE:To determine if family members perceive that hospice improves the care of dying nursing home residents during the last 3 months of life. DESIGN:Mailed survey. PARTICIPANTS:Family members for all nursing home hospice enrollees in North Carolina during a 6-month period. MEASUREMENTS:After residents' deaths, ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2000.tb06883.x
更新日期：2000-08-01 00:00:00
abstract：:A survey of 977 community subjects aged 65 or older identified 719 of them as not impaired in physical health. Of these, 104 (14 percent) perceived their physical status to be poor, whereas 615 (86 percent) accurately perceived it to be unimpaired. There were no significant differences between the two groups with rega...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1979.tb06051.x
更新日期：1979-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the use of newer psychotropic agents in nursing home residents in the era of new Health Care Financing Administration (HCFA) guidelines. DESIGN:Retrospective chart review of referrals to an on-site geriatric psychiatry service in seven Eastern Massachusetts facilities during 1995-1996. SUBJECTS:...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1998.tb02540.x
更新日期：1998-02-01 00:00:00
abstract：OBJECTIVES:To investigate the relationship between insomnia and 6-year survival among older, community-dwelling, white women. DESIGN:Longitudinal study. SETTING:The sample was selected randomly from a 20-census tract area of Baltimore, Maryland. PARTICIPANTS:In 1984, 778 women aged 65 years and older participated in...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1998.tb04544.x
更新日期：1998-10-01 00:00:00
abstract：OBJECTIVE:To assess how dietary change affects gain in strength and muscle mass during heavy resistance training of elderly men. DESIGN:Randomized controlled trial. INTERVENTION:During 12 weeks of resistance training of knee extensors and flexors, a daily supplement of 560 +/- 16 kcal/day (17% energy from protein, 43...
journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1532-5415.1992.tb01937.x
更新日期：1992-02-01 00:00:00
abstract：OBJECTIVES:To understand characteristics of older at-risk drinkers and reasons why they decide to change or maintain their alcohol consumption. DESIGN:Secondary analysis of data from a randomized controlled trial to reduce drinking in at-risk drinkers. SETTING:Three primary care sites in southern California. PARTICI...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/jgs.12394
更新日期：2013-08-01 00:00:00
