Abstract:
:Seroma formation is a common postoperative complication in plastic surgery, resulting in notable patient morbidity and expense. In this study the authors investigated the efficacy of a synthetic glutaraldehyde-based tissue adhesive (BioGlue; Cryolife, Inc., Kennesaw, GA) in seroma prevention in the rat mastectomy seroma model. This tissue adhesive is composed of purified bovine serum albumin (45%) and glutaraldehyde (10%). Twenty-two Sprague-Dawley rats received mastectomies along with axillary lymphadenectomy and disruption of subcutaneous lymphatics. The control group (N = 11) received 2.5 ml saline into the wound before closure. In the experimental group (N = 11), 2.5 ml BioGlue was injected into the wound. On postoperative day 7, the resultant seromas were quantified and adjacent tissues were harvested for histological examination. The rats in the control group had a mean seroma volume of 5.19 ml (standard deviation, +/- 3.65 ml; N = 11), whereas the rats treated with BioGlue had a mean seroma volume of 0.25 +/- 0.43 ml (N = 11). Histology revealed an inflammatory response consistent with postoperative changes as well as a mild foreign body reaction. This study demonstrates that BioGlue can be used as a tissue adhesive that reduces seroma formation significantly in the rat mastectomy model (p = 0.0008). Further studies are warranted to investigate the long-term effect of BioGlue on surrounding tissue.
journal_name
Ann Plast Surgjournal_title
Annals of plastic surgeryauthors
Menon NG,Downing S,Goldberg NH,Silverman RPdoi
10.1097/01.SAP.0000054182.47311.17subject
Has Abstractpub_date
2003-06-01 00:00:00pages
639-43issue
6eissn
0148-7043issn
1536-3708journal_volume
50pub_type
杂志文章abstract::Mastectomy has traditionally been performed using a transverse elliptical incision. The disadvantages of this approach are a potentially visible scar medially and poor subincisional soft-tissue coverage of implants laterally. A more natural and aesthetic result is obtained with an oblique incision running parallel to ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000119
更新日期:2014-01-01 00:00:00
abstract::Ectopic bone formation or "heterotopic ossification" can follow surgery, trauma, or neurologic injury, but the process is usually self-limited, localized to the site of injury, and responds to surgical treatment when necessary. Aggressive, systemic forms of heterotopic ossification exist that generate lesions that oft...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000099624.04554.63
更新日期:2004-03-01 00:00:00
abstract::The sural artery flap is a distally based fasciocutaneous flap. It is based on a reverse flow through anastomoses between the peroneal artery and the communicating vascular network of the medial sural nerve. In the difficult area of defects in the lower leg and the ankle and heel region, it has a wide variety of indic...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199807000-00011
更新日期:1998-07-01 00:00:00
abstract::In cases of severe macromastia, the free nipple graft technique has been the traditional alternative to pedicle transposition. Distress over nipple survival in large reduction mammaplasty and long pedicle transposition is largely responsible for this.A retrospective investigation of the records of 142 reduction mammap...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000174363.04135.b9
更新日期:2005-09-01 00:00:00
abstract::A new pair of forceps incorporating two skin hooks and needle driver tips on an Adson forceps frame is described. Its use, advantages, and disadvantages are outlined. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199106000-00019
更新日期:1991-06-01 00:00:00
abstract::A total of 97 cases of metastatic basal cell carcinoma have been reported in the literature, 22 of which were metastatic to bone. To date there has been no survival following bone metastasis. A case report of significant long-term survival--over three times the expected--is presented. The treatment described is perhap...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-197912000-00010
更新日期:1979-12-01 00:00:00
abstract:BACKGROUND:Facial contour deformities usually result from congenital abnormalities, trauma, and the aging process. All depressions in the face, including glabella wrinkles and mild retrogression of chins, fall in this category. Local injection of autogenous fat parcels has been introduced for correction of these facial...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000248110.59452.49
更新日期:2007-06-01 00:00:00
abstract::Several perforator-based flaps have been developed recently and, although preoperative evaluation of perforator vessels is important, the conventional method using the Doppler flowmeter is still being used. The authors tried to identify perforator vessels in the abdominal region using scanning laser Doppler imaging an...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200206000-00008
更新日期:2002-06-01 00:00:00
abstract::The vascularized whole femur transplantation model is one of the commonly used vascularized bone marrow transplant models. It involves technical complexity and morbidities. To optimize this model, we took 2/3 femur as the carrier of bone marrow cells, and developed a vascularized partial femur model. Four experimental...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000114
更新日期:2014-12-01 00:00:00
abstract::Biologic prostheses have emerged to address the limitations of synthetic materials for ventral hernia repairs; however, they lack experimental comparative data. Fifteen swine were randomly assigned to 1 of 3 bioprosthetic groups (DermaMatrix, AlloDerm, and Permacol) after creation of a full thickness ventral fascial d...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181e051ed
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Lymphedema, a chronic disfiguring condition resulting from lymphatic dysfunction or disruption, can be difficult to accurately diagnose and manage. Of particular challenge is identifying the presence of clinically significant limb swelling through simple and noninvasive methods. Many historical and currently...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000244977.84130.cf
更新日期:2007-05-01 00:00:00
abstract::There is still controversy about the correlation of thrombocytosis and thrombosis complication. Using a rodent splenectomy-induced thrombocytosis model and a thrombogenic endothelial damage model (inverted suture resulting in an intraluminal thrombogenic adventitia of divided femoral artery), the authors investigated ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200301000-00010
更新日期:2003-01-01 00:00:00
abstract::Transverse facial clefts (macrostomia) are rare disorders that result when the embryonic mandibular and maxillary processes of the first branchial arch fail to fuse properly to form the corners of the mouth. Macrostomia may be seen alone or in association with other anomalies. It may be unilateral, extending along a l...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181e6cfc1
更新日期:2011-04-01 00:00:00
abstract::Cranioplasty using a synthetic material is less than ideal, especially if there is a history of infection at the defect site. Split-rib cranioplasty is a practical approach even in patients with a positive history of infection at or around the defect. We briefly review the historical background of split-rib cranioplas...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198111000-00001
更新日期:1981-11-01 00:00:00
abstract::Traditional gastrocnemius flap harvest requires a long skin incision, starting from the popliteal fossa to the mid leg. The authors designed three instruments to facilitate harvest of this flap through a small incision without the help of an endoscope in 10 patients. All 10 gastrocnemius muscle flaps survived with a 1...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200108000-00005
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:Evidence suggesting that adipose tissue is a metabolically active tissue has generated debate on the effects of large-volume liposuction (LVL) on metabolic and cardiovascular health. Given the inconsistency in the literature, the authors performed a systematic review to identify available evidence in order t...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/SAP.0000000000001195
更新日期:2017-12-01 00:00:00
abstract::Dupuytren's contracture, a benign condition characterized by fibrosis of the palmar and digital fascia, may be a debilitating condition that limits daily function. Several techniques exist for managing symptomatic contractures of the hand related to Dupuytren's. These techniques include the more invasive open fascioto...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/SAP.0000000000001607
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:Patients with necrotizing fasciitis are managed with multiple prompt, radical surgical debridements and critical care support. Debridement and reconstruction are often provided by different surgical teams. Anecdotally, single-specialty management seemed to be a more efficient management strategy. This study aim...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000173
更新日期:2014-05-01 00:00:00
abstract::Disciplines using human body surface dimensions require accurate, repeatable measurements. This study presents a design for the analysis of repeatability, precision, and validation of a new anthropometric device. This model enables estimation of the proportion of the total variation attributable to each level of data ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199504000-00004
更新日期:1995-04-01 00:00:00
abstract:BACKGROUND:This study sought to examine the feasibility and effectiveness of the use of ultrasound (US) as a clinical adjunct in the delivery of botulinum toxin for the treatment of Raynaud disease of the hand. METHODS:One cadaver hand was injected with a colored simulation material using the current traditional surfa...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002303
更新日期:2020-06-01 00:00:00
abstract::The authors describe a case of microvascular ear replantation with repair of the artery only and medicinal leech therapy that survived for 14 days but ultimately failed as a result of the absence of development of venous channels between the replant and the recipient bed. A 35-year-old man presented with complete avul...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200104000-00016
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND:According to the American Society of Plastic Surgeons (2007), the number of cosmetic procedures has increased to over 10 million in 2006, representing a 48% increase from 2000. This increase in cosmetic surgery prevalence is paralleled by a surge in reality cosmetic surgery television programming. METHODS:T...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31817e2cb8
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:This study aims to understand the degree to which ptosis is recognizable to a layperson. METHODS:Fifteen color drawings of a gender-neutral human face were created. Six faces exhibited right-sided ptosis (decreased margin reflex distance 1 and lengthened tarsal platform show) of 0.5 mm, 1 mm, 1.5 mm, 2 mm, 2.5...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001524
更新日期:2018-09-01 00:00:00
abstract::A new surgical technique for upper lip augmentation is presented. In this technique, 2 vertically parallel V-shaped incisions placed in a "V in V" fashion are used. Remarkable augmentation of the lip is provided by V-to-Y closure of the incisions. Over 7 years, this new technique, namely, V-Y in V-Y procedure, was use...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000205774.40210.58
更新日期:2006-06-01 00:00:00
abstract:BACKGROUNDS:The aims of the present study were to determine the exact level of separation of the upper lateral cartilage from the septal cartilage, and to classify the patterns of connection between the upper lateral cartilage and the lower lateral cartilage. METHODS:We dissected and photographed 60 sides of noses; 18...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31826cb00e
更新日期:2014-07-01 00:00:00
abstract::The authors report a method of reconstruction of a full-thickness lower eyelid defect using a blepharoplasty technique utilizing excess skin of the lower eyelid with a hard palate mucosal graft. In all patients the hard palate mucosa took well, and good functional and aesthetic results were obtained. The most suitable...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199906000-00019
更新日期:1999-06-01 00:00:00
abstract::With a rise in tissue expander-based breast reconstructions (TEBRs) using acellular dermal matrix (ADM), we have seen an increase in ADM-specific complications. In this study, we aimed to evaluate clinically significant seroma (CSS) formation-defined by the need for a drainage procedure-to determine if there was a dif...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3182923dc9
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Measurement of extremity volume is the most commonly used method for evaluation of lymphedema. However, volumetry would be inappropriate for comparing patients with different physiques, because body-type significantly affects extremity volume. Thus, we cannot evaluate using absolute values. To overcome this ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002505
更新日期:2021-01-01 00:00:00
abstract::To evaluate the management and outcome of acute facial powder burns, 10 patients admitted to a burn center (1980-1985) were reviewed. Facial burns resulted from black gun-powder in 7 and fireworks in 3 patients. Most burns occurred in teenage boys (6) and all but 1 were the result of carelessness on the part of the bu...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198708000-00009
更新日期:1987-08-01 00:00:00
abstract::The totem pole rib bone graft for nasal reconstruction is presented as an effective way to prepare the donor bone for the correction of saddle-nose deformity. The article's title emanates from the fact that when the sculpturing of the rib is completed it has the appearance of a totem pole before the separate parts are...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198310000-00003
更新日期:1983-10-01 00:00:00