Reactive thrombocytosis without endothelial damage does not affect the microvascular anastomotic patency.

Abstract:

:There is still controversy about the correlation of thrombocytosis and thrombosis complication. Using a rodent splenectomy-induced thrombocytosis model and a thrombogenic endothelial damage model (inverted suture resulting in an intraluminal thrombogenic adventitia of divided femoral artery), the authors investigated whether reactive thrombocytosis with or without endothelial damage contributes to the patency of microvascular anastomosis. Four experimental groups were evaluated in this study: 1) sham operation without thrombogenic anastomosis after femoral artery division; 2) sham operation with thrombogenic anastomosis; 3) thrombocytosis alone without thrombogenic anastomosis; 4) thrombocytosis with thrombogenic anastomosis (each subgroup n = 10, total N = 40). Vascular patency was assessed after immediate operation and on the seventh day postoperatively. Platelet counts and platelet activation (CD62P) were studied in correlation to microvascular patency. In rats without thrombogenic anastomosis groups, there were no significant differences in CD62P expression on platelets (p = 0.09), the patency rates (p = 0.561), or perfusion units (p = 0.746) before and after arterial reanastomosis between rats with and without thrombocytosis, respectively. However, the thrombogenic anastomosis of femoral artery in thrombocytosis and control groups showed significantly increased CD62P expression (p < 0.05), decreased the perfusion unit (p < 0.05), and patency rate (p < 0.001), compared with rats without thrombogenic anastomosis of femoral artery in both groups. In summary, this study demonstrates that microvascular anastomosis can be performed safely with reactive thrombocytosis alone without thrombogenic anastomosis. Meticulous microvascular anastomosis without triggering platelet activation is the most important factor to prevent thrombosed vessels in microsurgical anastomosis.

journal_name

Ann Plast Surg

authors

Kuo YR,Yang KD,Huang MN,Wei FC,Jeng SF

doi

10.1097/00000637-200301000-00010

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

57-63

issue

1

eissn

0148-7043

issn

1536-3708

pii

00000637-200301000-00010

journal_volume

50

pub_type

杂志文章
  • Periprosthetic breast abscess caused by Streptococcus pyogenes after scarlet fever.

    abstract::We present a case of a 32-year-old white women, affected by breast cancer and treated with mastectomy, who underwent immediate breast reconstruction with a tissue expander. She presented a periprosthetic infection from Streptococcus pyogenes (group A streptococcus, GAS) after scarlet fever. S. pyogenes may be responsi...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e31804636cf

    authors: Persichetti P,Langella M,Marangi GF,Vulcano E,Gherardi G,Dicuonzo G

    更新日期:2008-01-01 00:00:00

  • The axillary tree as a source of musculocutaneous and fasciocutaneous flaps in a fixed-skin porcine model.

    abstract::Our understanding of muscle, fascia, and skin flap physiology is based largely on data obtained from rodent, rabbit, or canine models. The presence of a well-developed panniculus carnosus confounds the extrapolation of data from these animals to humans. This study attempted to define microsurgically applicable musculo...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199805000-00005

    authors: Murphy RX Jr,Sonntag BV

    更新日期:1998-05-01 00:00:00

  • Obstetric brachial plexus injury in subsequent deliveries.

    abstract::It is well known that multiparas who had previously been delivered of newborns with obstetric brachial plexus palsy are at risk of having the same complication in subsequent deliveries. However, none of the studies in the literature have actually attempted to estimate how high is that risk. The aims of the current pap...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199611000-00015

    authors: al-Qattan MM,al-Kharfy TM

    更新日期:1996-11-01 00:00:00

  • Recombinant human epidermal growth factor (EGF) to enhance healing for diabetic foot ulcers.

    abstract::This paper studies the healing effect of recombinant human epidermal growth factor (EGF) on chronic diabetic foot ulcers. A total of 89 patients (65 male and 24 female) aged from 36 to 82 years (average of 54) enrolled for the prospective, open-label trial, crossover study. Predetermined criteria were used for diagnos...

    journal_title:Annals of plastic surgery

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.sap.0000198731.12407.0c

    authors: Hong JP,Jung HD,Kim YW

    更新日期:2006-04-01 00:00:00

  • Lateral-dorsal neurovascular island flaps for pulp reconstruction.

    abstract::Finger pulp loss is often observed in daily practice. When the lateral and dorsal surfaces of the injured digit remain intact, a neurovascular island flap can be designed and raised from that part of the finger for pulp reconstruction. Two types of homodigital lateral-dorsal neurovascular island flaps were used in 17 ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200045060-00008

    authors: Chen CT,Wei FC

    更新日期:2000-12-01 00:00:00

  • Postauricular Approach for Mandibular Angle Ostectomy: An Alternative for Shortening the Recovery Time.

    abstract::Many surgical procedures to improve mandibular contour have been introduced in East Asia. Despite consensus regarding mandible contouring surgery, surgery which includes angle ostectomy and lateral cortex excision, some patients require only mandibular angle ostectomy. The intraoral approach is a widely used method, b...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000000216

    authors: Lim H,Kang M

    更新日期:2016-01-01 00:00:00

  • The use of validated body image indices following panniculectomy.

    abstract::Limited data of body image and quality of life are available after panniculectomy. Although it is generally considered a medically necessary procedure, we believe that the benefits of this procedure are many. The Short Form of The Situational Inventory of Body Image Dysphoria Short Form and the Multidimensional Body S...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e31820b3af6

    authors: Singh KA,Losken A

    更新日期:2011-05-01 00:00:00

  • Cytokines: a primer for plastic surgeons.

    abstract::Cytokines are peptide mediators of inflammation that are being extensively studied in several aspects of disease. I provide an introduction to the general features of cytokine biology. Cytokines may be considered as either proinflammatory or anti-inflammatory compounds, and they also have potent hematopoietic effects....

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章,评审

    doi:10.1097/00000637-199511000-00021

    authors: Remick DG

    更新日期:1995-11-01 00:00:00

  • Adjustable Fat Repositioning With Intraoral Anchoring: A New Technique in Transconjunctival Blepharoplasty.

    abstract:BACKGROUND:Prominent tear trough deformity and midfacial depression are the first priority in periorbital rejuvenation. To achieve harmonious lower eyelid improvement, we developed a novel approach to reposition infraorbital fat using intraoral anchoring in transconjunctival lower eyelid blepharoplasty. METHODS:Fourte...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000002089

    authors: Gao W,Qiao C,Lin X

    更新日期:2019-10-01 00:00:00

  • Massive Localized Lymphedema: Analysis of Intraoperative Care.

    abstract::Massive localized lymphedema (MLL) is rare, but as the prevalence of obesity in adults rises, it can be foreseen that cases will increase in prevalence. These patients are unable to ambulate and have uncontrollable rash and skin breakdown. Operative management for MLL is offered when nonsurgical measures are ineffecti...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000001475

    authors: Moore E,Vasconez H,Wong L

    更新日期:2018-07-01 00:00:00

  • Relationship of the temporofrontal rami of the facial nerve to the fascial layers of the temporal region.

    abstract:BACKGROUND:Historically, dissection of the temporoparietal fascia immediately above the zygomatic arch has been avoided due to the risk of transection of the temporofrontal rami of the facial nerve. METHODS:A total of 8 fresh cadaveric hemi-faces have been dissected to investigate the relationship of the temporofronta...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e318221b563

    authors: O'Brien JX,Ashton MW

    更新日期:2012-06-01 00:00:00

  • Preferences for the white female nasal supratip break.

    abstract:BACKGROUND:The debate on how to create ideal facial proportions--once the remit of artists and sculptors--has been reignited during the past 5 decades, with the emergence of aesthetic facial surgery. Classic ideals exist, but few individuals actually satisfy these criteria. Aesthetic ideals are culturally and temporall...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e31823f3ca1

    authors: McArdle A,Young R,Kelly MH

    更新日期:2012-04-01 00:00:00

  • Crossover innervation after digital nerve injury: myth or reality?

    abstract::Several clinical studies promulgate the concept that some degree of crossover innervation occurs after digital nerve injuries are sustained and that the intact digital nerve might even substitute for the loss of nerve function on the injured side. Other studies strongly dispute the existence of this phenomenon. An exc...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200045050-00007

    authors: Weinzweig N

    更新日期:2000-11-01 00:00:00

  • One-stage immediate breast reconstruction with implant following skin-sparing mastectomy in Asian patients.

    abstract::The Asian breast reconstruction patient is usually of lower mean age, lower body mass index (BMI), and has relatively small breasts. This study aimed to investigate the outcome of 1-stage immediate breast reconstruction using saline-filled implants in the Asian patients.Between April 2002 and July 2005, 30 patients un...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e318063ef70

    authors: Wang HY,Ali RS,Chen SC,Chao TC,Cheng MH

    更新日期:2008-04-01 00:00:00

  • Methods of vascular pedicle coverage.

    abstract::Based on our clinical experience, various methods of donor or recipient vascular pedicle coverage for an arterialized or free flap are reported. The vascular pedicle may be placed in the subcutaneous space either by incising the skin along the full length of the vascular route or by passing it through a subcutaneous t...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-197910000-00003

    authors: Ohtsuka H,Hwang HY,Torigai K,Shioya N

    更新日期:1979-10-01 00:00:00

  • The medial sural MEDIAL GASTROCNEMIUS perforator free flap: an 'ideal' prone position skin flap.

    abstract::The medial sural MEDIAL GASTROCNEMIUS perforator flap is a potentially large, thin cutaneous flap that encompasses the calf skin territory. Its medial sural vascular pedicle has a long leash of large caliber that simplifies microanastomoses when used as a free flap. Because the identification of the requisite perforat...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.sap.0000095438.33962.31

    authors: Hallock GG,Sano K

    更新日期:2004-02-01 00:00:00

  • Repair of chronic mallet finger deformity using Mitek micro arc bone anchor.

    abstract::Surgical correction of chronic mallet finger caused by terminal tendon disruption was carried out in 22 patients. The distal stump of the tendon was fixed to the base of the distal phalanx with a Mitek micro arc bone anchor. In all patients the mallet finger deformity was corrected. There were 15 patients with excelle...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.sap.0000151464.03967.a2

    authors: Ulkür E,Açikel C,Ergun O,Celiköz B

    更新日期:2005-04-01 00:00:00

  • An unusual vascular pedicle in a deltopectoral free flap.

    abstract::An unusual vascular pedicle of a deltopectoral flap is reported and the case is discussed. We suggest noting any anomalies in the flap's vascularization during its dissection. ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-198002000-00017

    authors: Marconi F,Poppi V,Farese P

    更新日期:1980-02-01 00:00:00

  • Effect of recombinant human growth hormone on random pattern flaps in rats.

    abstract::Recombinant human growth hormone, a very potent anabolic hormone, plays a significant role in growth regulation, bone metabolism, and wound healing. This study evaluates its effect on random flap survival. Rats were randomly divided into 2 groups. A dorsal random flap, cephalically based, was used. One group received ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e318193498c

    authors: Shalom A,Hollander L,Westreich M

    更新日期:2009-11-01 00:00:00

  • Extended fasciocutaneous flaps for autologous augmentation mastopexy with upper body lift after massive weight loss: an early experience.

    abstract:INTRODUCTION:Common upper body findings after massive weight loss (MWL) include breast ptosis, projection loss, flattening, inframammary fold descent, and back rolls. Although implants address volume loss, manifestations of circumferential excess (ie, back rolls) are ignored. We review our experience with extended late...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000000413

    authors: Patel NB,Wong MS

    更新日期:2015-05-01 00:00:00

  • Combined laser therapy for difficult dermal pigmentation: resurfacing and selective photothermolysis.

    abstract::Treating pigmented lesions of the skin, especially deep dermal pigmentations, are difficult to achieve satisfactory results without complications. To treat dermal pigmentations, such as nevus of Ota and congenital nevus, the combined therapy of a resurfacing laser (CO2) and a selective photothermolytic laser (the Q-Sw...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200107000-00006

    authors: Park SH,Koo SH,Choi EO

    更新日期:2001-07-01 00:00:00

  • Computed tomography versus standard radiography in the assessment of fractures of the mandible.

    abstract::Twenty-nine fractures of the mandible were studied by standard radiographs and axial computed tomographic scans (hard copy). Independent reviewers analyzed each study in a blinded, non-paired fashion. When radiographic diagnostic sensitivities were compared on the basis of known surgical findings, the plain films were...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199208000-00002

    authors: Creasman CN,Markowitz BL,Kawamoto HK Jr,Cohen S,Kioumehr F,Hanafee WN,Shaw WW

    更新日期:1992-08-01 00:00:00

  • A distally based median plantar flap.

    abstract::The first metatarsophalangeal joint area is a very difficult one to reconstruct, needing skin that is thick, sensitive, and resistant to friction. Although the medial plantar island flap was initially described to resurface heel defects, we have used this flap as a cross-foot flap to recover the first metatarsophalang...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-198805000-00012

    authors: Amarante J,Martins A,Reis J

    更新日期:1988-05-01 00:00:00

  • Aesthetic Refinement in the Creation of the Clitoris, Its Preputial Hood, and Labia Minora in Male-to-Female Transsexual Patients.

    abstract:BACKGROUND:In male-to-female genital sex reassignment surgery, the clitoris, its prepuce, and the labia minora remain among the most difficult structures to construct. We describe the authors' clitoroplasty and vulvoplasty technique. METHODS:All patients who underwent male-to-female sex reassignment surgery at a singl...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000001532

    authors: Mañero Vazquez I,García-Senosiain O,Labanca T,Gómez Gil E

    更新日期:2018-10-01 00:00:00

  • Splitting advancement genioplasty: a new genioplasty technique.

    abstract::A new genioplasty technique has been described and performed on 16 patients since 1995. The technique has been developed to avoid some undesired results of the current osseous genioplasty techniques and to achieve a more natural appearance in advancement genioplasty. According to the authors' technique, a rectangular ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:

    authors: Celik M,Tuncer S,Büyükçayir I

    更新日期:1999-08-01 00:00:00

  • Silicon tissue assay: are there intracapsular variations?

    abstract::In previous studies, we were able to demonstrate baseline non-augmented cadaveric silicon tissue values as well as silicone-augmented breast capsular tissue silicon levels from various geographic locations in the United States. One of the limitations of these previous studies was the potential for intracapsular variat...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199612000-00004

    authors: Evans GR,Baldwin BJ

    更新日期:1996-12-01 00:00:00

  • Comparison of donor site dressings.

    abstract::A comparison study of donor site care using 5 common modalities was undertaken. A total of 210 treated donor areas were examined for healing differences, comfort, complications, and cost. At the conclusion of the study we were able to recommend certain treatment methods depending on the nature of the donor wound. ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-198009000-00013

    authors: Brady SC,Snelling CF,Chow G

    更新日期:1980-09-01 00:00:00

  • Clinical experience with the hatchet-shaped gluteus maximus musculocutaneous flap.

    abstract::One of the most frequently used flaps for the coverage of sacral skin and soft-tissue defects (primarily decubiti) is the gluteus maximus musculocutaneous flap. The authors have developed a new, hatchet-shaped incision direction for the flap and have been using it for 6 years in the surgical treatment of various pelvi...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.sap.0000171147.73420.25

    authors: Jósvay J,Sashegyi M,Kelemen P,Donáth A

    更新日期:2005-08-01 00:00:00

  • Immediate evaluation of neovascularization in a grafted bilayered artificial dermis using laser Doppler imaging.

    abstract:BACKGROUND:A bilayered artificial dermis is widely applied for skin defects. Its collagen sponge is biodegraded and replaced with dermis-like tissue after application. There is no reliable method for quantitatively evaluating the blood flow of artificial dermis. In this study, we used laser Doppler imaging to evaluate ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e3182590948

    authors: Morimoto N,Takemoto S,Kawai K,Aya R,Ishisaka T,Suzuki S

    更新日期:2014-01-01 00:00:00

  • The Biointegration of a Porcine Acellular Dermal Matrix in a Novel Radiated Breast Reconstruction Model.

    abstract:BACKGROUND:Ideal acellular dermal matrices (ADM) for breast reconstruction exhibit native extracellular matrix (ECM) structure to allow rapid biointegration and appropriate mechanical properties for desired clinical outcomes. In a novel in vivo model of irradiated breast reconstruction, we describe the cellular and vas...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000002277

    authors: Cottler PS,Sun N,Thuman JM,Bielak KMH,Salopek LS,Piñeros-Fernandez A,Hu S,Campbell CA

    更新日期:2020-06-01 00:00:00