Influence of Large-Volume Liposuction on Metabolic and Cardiovascular Health: A Systematic Review.

Abstract:

BACKGROUND:Evidence suggesting that adipose tissue is a metabolically active tissue has generated debate on the effects of large-volume liposuction (LVL) on metabolic and cardiovascular health. Given the inconsistency in the literature, the authors performed a systematic review to identify available evidence in order to elucidate the potential impact of LVL on metabolic markers and cardiovascular risk factors. METHODS:A PubMed search using relevant keywords was conducted. Articles were screened using predetermined inclusion and exclusion criteria. Large-volume liposuction was defined as greater than 3.5 L of lipoaspirate. All studies included evaluation of patients' preoperative and postoperative cardiovascular risk factors, inflammatory cytokines, and/or insulin resistance/sensitivity. Relevant studies were evaluated and assigned a level of evidence. RESULTS:A total of 12 studies that met the inclusion criteria were reviewed, of which 1 was a continuation of a previous study. All reports were prospective studies, 2 were randomized control trials, and 3 included a control group. A total of 364 patients were pooled for analysis. The mean volume of lipoaspirate was 7440 ± 1934.9 mL. The mean body mass index at baseline and postliposuction was 30.7 and 28.4, respectively. Seven studies reported a trend toward decrease in total cholesterol levels with an overall mean reduction of 0.21 ± 0.05 mmol/L from 4.6 ± 0.79 mmol/L to 4.4 ± 0.74 mmol/L. After LVL, leptin was reported to significantly decrease in 4 studies, and TNF-α was reported to significantly decrease in 2. Adiponectin was reported to significantly increase in 2 studies. IL-6 decreased significantly in 2 studies. Two studies included participants with type II diabetes mellitus, whereas 10 studies evaluated insulin sensitivity. Of these, 6 studies reported improvement in insulin sensitivity. Six studies represented level IV and 6 represented level II evidence. CONCLUSIONS:Liposuction is among the most common aesthetic procedures performed with advances that make it possible to remove considerable amount of adipose tissue within a short period. Current data, although conflicting, appear to support the notion that LVL can affect cardiovascular risk factors, metabolic balance, and insulin resistance in positive ways. Future research with prospective studies is needed to clarify the role of LVL in improving overall health.

journal_name

Ann Plast Surg

authors

Sailon AM,Wasserburg JR,Kling RR,Pasick CM,Taub PJ

doi

10.1097/SAP.0000000000001195

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

623-630

issue

6

eissn

0148-7043

issn

1536-3708

journal_volume

79

pub_type

杂志文章,评审
  • Medial epicanthoplasty without a vertical scar.

    abstract:BACKGROUND:The epicanthal fold (Mongolian fold) in Asians reduces the aesthetic results of eyelid surgery, and thus, medial epicanthoplasty is commonly performed in combination with a double fold operation or blepharoptosis correction. Epicanthoplasty is one of the most popular cosmetic operations conducted in Asia, bu...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e31826eabbc

    authors: Park DH,Park SU,Lee BK,Lee YB,Do ER,Han DG,Shim JS,Lee YJ

    更新日期:2014-07-01 00:00:00

  • Benign fatty tumors of the peripheral nerves.

    abstract::Fatty tumors of the peripheral nerves, although rare, occur with sufficient frequency to pose problems in diagnosis and treatment. Moreover, the nomenclature of these tumors has suffered from controversy over their morpological description. These factors have contributed to a misunderstanding about the treatment of th...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-197803000-00011

    authors: Terzis JK,Daniel RK,Williams HB,Spencer PS

    更新日期:1978-03-01 00:00:00

  • Preliminary report of in vitro reconstruction of a vascularized tendonlike structure: a novel application for adipose-derived stem cells.

    abstract:INTRODUCTION:A greater supply of tendinous tissue can be obtained through tissue engineering technology with increasing application of adult stem cells. It is well known that adipose-derived stem cells (ADSCs), found in abundance in adipose tissue, have the same differentiating capacity as mesenchymal stem cells yet ha...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e3182583e99

    authors: Vindigni V,Tonello C,Lancerotto L,Abatangelo G,Cortivo R,Zavan B,Bassetto F

    更新日期:2013-12-01 00:00:00

  • The role of external cranial fixation in simplifying scalp composite tissue transfer.

    abstract::The use of external devices for cranial suspension or immobilization may facilitate the transfer of skin grafts or flaps needed for scalp coverage. Skull tongs are readily available in any trauma center. Following composite tissue transfer to the skull, skull tongs can prevent compromise of the microanastomoses or the...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-198901000-00015

    authors: Hallock GG

    更新日期:1989-01-01 00:00:00

  • The superior dermoglandular pedicle approach to breast reduction.

    abstract::The superior dermoglandular pedicle technique of breast reduction and its results in 193 reductions are presented. This technique offers aesthetically pleasing results, sensate nipple/areola complex, and safety. The natural shape obtained results from preservation of the superior portion of the breast tissue (where ti...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199209000-00004

    authors: Robbins LB,Hoffman DK

    更新日期:1992-09-01 00:00:00

  • An alternative approach for correction of Stahl's ear.

    abstract::A technique of correction of Stahl's ear is presented and is compared with other techniques reported in the literature. ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.SAP.0000067728.84041.96

    authors: Al-Qattan MM,Hashem FK

    更新日期:2004-01-01 00:00:00

  • Accelerated diabetic wound healing using cultured dermal fibroblasts retrovirally transduced with the platelet-derived growth factor B gene.

    abstract::The treatment of diabetic wounds is a considerable clinical challenge. In this study, mouse dermal fibroblasts retrovirally transduced with the human platelet-derived growth factor B (PDGF-B) gene were used to treat diabetic mouse wounds. The PDGF-B gene was obtained from human umbilical vein endothelial cells, cloned...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.SAP.0000084461.83554.71

    authors: Breitbart AS,Laser J,Parrett B,Porti D,Grant RT,Grande DA,Mason JM

    更新日期:2003-10-01 00:00:00

  • Anthropometric optical surface imaging system repeatability, precision, and validation.

    abstract::Disciplines using human body surface dimensions require accurate, repeatable measurements. This study presents a design for the analysis of repeatability, precision, and validation of a new anthropometric device. This model enables estimation of the proportion of the total variation attributable to each level of data ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199504000-00004

    authors: Kohn LA,Cheverud JM,Bhatia G,Commean P,Smith K,Vannier MW

    更新日期:1995-04-01 00:00:00

  • Craniosynostotic variations in syndromic, identical twins.

    abstract::Despite intense research, etiologies underlying syndromic craniosynostosis remain poorly understood. While syndrome-related genetic factors have garnered much attention, external forces likely play a large role as well. In contrast to well-defined genetic abnormalities that may be precisely identified and statisticall...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e31815d5c14

    authors: Sher S,Cole P,Kaufman Y,Hatef DA,Hollier L

    更新日期:2008-09-01 00:00:00

  • Preferences for the white female nasal supratip break.

    abstract:BACKGROUND:The debate on how to create ideal facial proportions--once the remit of artists and sculptors--has been reignited during the past 5 decades, with the emergence of aesthetic facial surgery. Classic ideals exist, but few individuals actually satisfy these criteria. Aesthetic ideals are culturally and temporall...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e31823f3ca1

    authors: McArdle A,Young R,Kelly MH

    更新日期:2012-04-01 00:00:00

  • Atypical Mycobacterial Infections After Plastic Surgery Procedures Abroad: A Multidisciplinary Algorithm for Diagnosis and Treatment.

    abstract:BACKGROUND:The recent rise in medical tourism, especially for cosmetic procedures, has been mirrored by an increase in the incidence of infections with Mycobacterium abscessus, which is an atypical mycobacterium that is ubiquitous in aquatic environments. M. abscessus soft tissue infections arise from the use of improp...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000002061

    authors: Leto Barone AA,Grzelak MJ,Frost C,Ngaage LM,Ge S,Kolegraff K,Chopra K,Tornheim JA,Caffrey J,Lifchez SD,Rasko Y

    更新日期:2020-03-01 00:00:00

  • One-stage arterialized nasolabial island flap for floor of mouth reconstruction.

    abstract::A one-stage nasolabial island flap isolated on the facial artery and vein is described for floor of mouth reconstruction. The donor site is closed primarily. The advantages of the procedure are that the one-stage procedure obviates the need for division and inset of a distant flap, the arterialized flap brings its own...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-198101000-00012

    authors: Rose EH

    更新日期:1981-01-01 00:00:00

  • Managing Vascular Anomalies in the Era of Genetics and Precision Medicine: An Opportunity or a Challenge?

    abstract:ABSTRACT:The era of genetics and precision medicine has been reforming this world. How will plastic surgeons in the field of vascular anomalies conform to the trend? This article systematically reviews the identification of serum biomarkers, risk factors, specific mutations in the angiogenesis-related genes such as GNA...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000002723

    authors: Gu H,Liu H,Cai R,Chen H,Lin X

    更新日期:2021-01-19 00:00:00

  • Upper lateral cartilage fold-in flap: a combined spreader and/or splay graft effect without cartilage grafts.

    abstract::Dorsal hump reduction almost always breaks the internal nasal valve and nasal obstruction is likely to occur postoperatively, unless reconstructed. One hundred eighty patients were operated using both open and closed rhinoplasty approaches. Upper lateral cartilages were meticulously separated from their junction with ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e31816dd359

    authors: Ozmen S,Ayhan S,Findikcioglu K,Kandal S,Atabay K

    更新日期:2008-11-01 00:00:00

  • Direct-To-Implant and 2-Stage Breast Reconstruction After Nipple Sparing Mastectomy: Results of a Retrospective Comparison.

    abstract::Breast reconstruction after nipple sparing mastectomy (NSM) plays, nowadays, a fundamental role in breast cancer management. There is no consensus on the best implant-based reconstruction technique, considering 2 stages (expander-prosthesis) or direct-to-implant (DTI). A retrospective review of consecutive adult femal...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000001893

    authors: Pallara T,Cagli B,Fortunato L,Altomare V,Loreti A,Grasso A,Manna E,Persichetti P

    更新日期:2019-10-01 00:00:00

  • Construction of penis with two free flaps.

    abstract::A case of penis construction using two free flaps is presented. The urethra is constructed with an ulnar forearm flap and external coverage is provided with deltoid flap. The biggest disadvantage with radial forearm flap, which is considered to be the most ideal donor flap for penile construction, is its large and uns...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200209000-00011

    authors: Harashina T,Inoue Y,Takamatsu A,Wakamatsu K,Takeshita A,Miura H

    更新日期:2002-09-01 00:00:00

  • Saphenous neurocutaneous island flap model in the rat: evaluation of vascular supply.

    abstract::Neurocutaneous flaps are utilized routinely in reconstructive surgery and even more so during the past decade. In this study, the vascular supply of the neurocutaneous flap in the rat model is presented and evaluated. Thirty-six flaps (3.5x3 cm2) were dissected on the medial aspect of the leg based on a pedicle of the...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199910000-00012

    authors: Dogan T,Zhang F,Komorowska-Timek E,Shi DY,Lineaweaver WC,Buncke HJ

    更新日期:1999-10-01 00:00:00

  • Microsurgical ear replantation without venous repair: failure of development of venous channels despite patency of arterial anastomosis for 14 days.

    abstract::The authors describe a case of microvascular ear replantation with repair of the artery only and medicinal leech therapy that survived for 14 days but ultimately failed as a result of the absence of development of venous channels between the replant and the recipient bed. A 35-year-old man presented with complete avul...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200104000-00016

    authors: Akyürek M,Safak T,Keçik A

    更新日期:2001-04-01 00:00:00

  • Traumatic hemipelvectomy.

    abstract::Traumatic hemipelvectomy is an uncommon and devastating injury with few patients alive when they reach the hospital. There are only 19 reported survivors of this injury. This group includes 17 males and 2 females. All had severe, associated injuries. The mechanism of injury involved motorcycle, automobile, pedestrian/...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章,评审

    doi:10.1097/00000637-199108000-00011

    authors: Klingman RR,Smith P,Stromberg B,Valentine J,Goebel M

    更新日期:1991-08-01 00:00:00

  • Cerebriform fibrous proliferation vs. proteus syndrome.

    abstract::Proteus syndrome is a rare, congenital hamartomatous syndrome that presents with a wide range of abnormalities. Regardless of different manifestations found in different patients, there exists three mandatory criteria for the diagnosis of this syndrome: a mosaic distribution of the lesions, a progressive course, and s...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200112000-00016

    authors: Yavuzer R,Uluoğlu O,Sari A,Boyacioğlu M,Sarigüney Y,Latifoğlu O,Celebi MC

    更新日期:2001-12-01 00:00:00

  • Plastic Surgery and the COVID-19 Pandemic: A Review of Clinical Guidelines.

    abstract:BACKGROUND:A novel coronavirus disease (COVID-19) was first reported in December 2019 in China and was soon declared a pandemic by the World Health Organization. Many elective and nonessential surgeries were postponed worldwide in an effort to minimize spread of disease, as well as to conserve resources. Our goal with ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000002443

    authors: Ozturk CN,Kuruoglu D,Ozturk C,Rampazzo A,Gurunian Gurunluoglu R

    更新日期:2020-08-01 00:00:00

  • Long-term follow-up of a modified Anton-Hartrampf nipple reconstruction.

    abstract::This study was performed to determine the degree of shrinkage over time in nipple projection after reconstruction. Nipple-areolar reconstruction was performed using the modified Anton-Hartrampf technique, and pigmentation was achieved with tattooing. This study looked at 28 consecutive patients with nipple reconstruct...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199911000-00001

    authors: Banducci DR,Le TK,Hughes KC

    更新日期:1999-11-01 00:00:00

  • Outcome of the Modified Meek Technique in the Management of Major Pediatric Burns.

    abstract:INTRODUCTION:The modified Meek micrografting technique has been used in the treatment of severely burned patients and a number of articles have examined the use of the modified Meek technique in adults and in mixed-age groups. However, there is a paucity of research pertaining to the outcome in the pediatric age group....

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000001565

    authors: Lee SZ,Halim AS,Wan Sulaiman WA,Mat Saad AZ

    更新日期:2018-09-01 00:00:00

  • Nodal metastatic melanoma in the neck of a 4-year-old girl after diagnosis of Spitz nevus of the cheek.

    abstract::A 4-year-old girl was referred to the plastic surgery unit with metastatic malignant melanoma diagnosed in a cervical lymph node. She had previously undergone excision of a Spitz nevus of the cheek at age 18 months. The management of this patient is discussed along with a review of the literature relating to Spitz nev...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.SAP.0000037277.03962.4F

    authors: Reynolds N,Ali-Khan AS,Rigby H,Orlando A

    更新日期:2003-05-01 00:00:00

  • A new technique for closure of infraorbital defects.

    abstract:BACKGROUND:The infraorbital region is a unique facial subunit surrounded with several important structures, such as the lower eyelids, oral commissure, ala nasi, and the sideburns. The potential for distortion of these neighboring anatomic landmarks and the absence of natural creases where incisional scars can be camou...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e31820d6830

    authors: Mutaf M,Günal E,Temel M

    更新日期:2011-12-01 00:00:00

  • Honey-medicated dressing: transformation of an ancient remedy into modern therapy.

    abstract::Honey has been applied for medicinal purposes since ancient times. Its antibacterial effects have been established during the past few decades. Still, modern medical practitioners hesitate to apply honey for local treatment of wounds. This may be explained by the expected messiness of such local application. Moreover,...

    journal_title:Annals of plastic surgery

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.SAP.0000032306.44107.C1

    authors: Ahmed AK,Hoekstra MJ,Hage JJ,Karim RB

    更新日期:2003-02-01 00:00:00

  • Medical canthoplasty with the Mitek Anchor System.

    abstract::A variety of surgical techniques have been described for medial canthal tendon reattachment. They generally require technical skill and prolonged operating time. We have applied a new device, the Mitek Anchor System, in reattaching the medial canthal tendon to the medial orbital wall in 3 patients, and got excellent t...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199702000-00005

    authors: Okazaki M,Akizuki T,Ohmori K

    更新日期:1997-02-01 00:00:00

  • Toward an understanding of nonsyndromic craniosynostosis: altered patterns of TGF-beta receptor and FGF receptor expression induced by intrauterine head constraint.

    abstract::Although the etiology of nonsyndromic forms of craniosynostosis remains uncertain, recent experiments from our laboratory have demonstrated that fetal head constraint induces cranial suture fusion in mice through a process associated with altered patterns of transforming growth factor beta (TGF-beta) isoform expressio...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200105000-00015

    authors: Hunenko O,Karmacharya J,Ong G,Kirschner RE

    更新日期:2001-05-01 00:00:00

  • Early psychological stress after forearm nerve injuries: a predictor for long-term functional outcome and return to productivity.

    abstract::Forearm and wrist injuries can result in a nonfunctional hand caused by loss of motor and sensory functions. Psychological stress is known to accompany traumatic hand injuries and may therefore affect functional outcome. The authors conducted a retrospective study of 107 patients diagnosed with a median, ulnar, or com...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200207000-00013

    authors: Jaquet JB,Kalmijn S,Kuypers PD,Hofman A,Passchier J,Hovius SE

    更新日期:2002-07-01 00:00:00

  • Giant keratoacanthomas.

    abstract::A patient with multiple keratoacanthomas association with a well-differentiated squamous cell carcinoma is presented. Incomplete excision of a keratoacanthoma deprives the pathologist of his main criteria in differentiating this lesion from a squamous cell carcinoma. Wide excision appears to be the treatment of choic...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-197908000-00015

    authors: Pickrell K,Villarreal-Rios A,Neale H

    更新日期:1979-08-01 00:00:00