The effect of calcineurin inhibitors on endothelial function in renal transplant recipients.

abstract：:This multicenter, randomized trial aimed to compare the safety and efficacy of an early reduction in corticosteroid dose vs. long-term maintenance in Brazilian patients on an immunosuppressive regimen based on tacrolimus and mycophenolate mofetil (MMF). In the control arm, prednisone was progressively reduced from day...

journal_title：Clinical transplantation

authors： Garcia VD,Carvalho DB,Gonçalves RT,Cavalcanti RL,Campos HH,Abbud-Filho M,Lobao-Neto AA

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Elderly patients are the fastest growing population requiring renal replacement therapy. As previous studies have shown a survival benefit of kidney transplantation compared to dialysis for end-stage renal disease, we sought to evaluate if this survival benefit extends to octogenarians. METHODS:This was a s...

journal_title：Clinical transplantation

authors： Ravichandran BR,Sparkes TM,Masters BM,Thomas B,Demehin M,Bromberg JS,Haririan A

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:The therapeutic drug monitoring of mycophenolic acid (MPA) has been investigated for renal and heart transplantations; however, its usefulness in lung transplantation is unclear. METHODS:The MPA area under the plasma concentration-time curve (AUC) was calculated in 59 adult lung transplant recipients. The M...

journal_title：Clinical transplantation

authors： Yabuki H,Matsuda Y,Watanabe T,Eba S,Hoshi F,Hirama T,Oishi H,Sado T,Noda M,Sakurada A,Kikuchi M,Yamaguchi H,Mano N,Okada Y

更新日期：2020-12-01 00:00:00

abstract：:These updated guidelines from the Infectious Diseases Community of Practice of the American Society of Transplantation review the diagnosis, prevention, and management of tuberculosis in the pre- and post-transplant period. The challenges of screening for both latent and active TB in the setting of transplantation are...

journal_title：Clinical transplantation

authors： Subramanian AK,Theodoropoulos NM,Infectious Diseases Community of Practice of the American Society of Transplantation.

更新日期：2019-09-01 00:00:00

abstract：:Auxiliary liver transplantation (ALT) is known to correct liver-based metabolic disorders. However, it remains unclear whether the presence of a native liver influences the long-term prognosis of ALT for metabolic diseases. We reported on a 4-yr-old girl who had undergone living-related auxiliary partial orthotopic li...

journal_title：Clinical transplantation

authors： Komatsu H,Inui A,Fujisawa T,Sogo T,Miyagawa Y,Inui M,Uemoto S,Inomata Y,Tanaka K

更新日期：1999-08-01 00:00:00

abstract：:Haploidentical stem cell transplantation (SCT) is increasingly used to treat pediatric patients with malignant or nonmalignant hematological disorders. The CD34+ dose of bone marrow or peripheral blood stem cells (PBSCs) has been shown to be an important determinant of the transplant outcome in adults under various pr...

journal_title：Clinical transplantation

authors： Chen Y,Xu LP,Liu KY,Chen H,Chen YH,Zhang XH,Wang Y,Wang FR,Han W,Wang JZ,Yan CH,Huang XJ

更新日期：2017-02-01 00:00:00

abstract：:Although steroid avoidance and withdrawal in renal transplant recipients (RTR) are actively being evaluated by physicians, the attitudes of recipients toward steroid use have not been systematically studied in the modern era. We conducted a confidential written survey of single-organ adult RTR pertaining to prednisone...

journal_title：Clinical transplantation

authors： Prasad GV,Nash MM,McFarlane PA,Zaltzman JS

更新日期：2003-04-01 00:00:00

abstract：:Temporary graft dysfunction with gas exchange abnormalities is a common finding during the postoperative course of a lung transplant and is often determined by the post-reimplantation syndrome. Supportive measures including oxygen by mask, inotropes, diuretics, and pulmonary vasodilators are usually effective in non-s...

journal_title：Clinical transplantation

authors： Feltracco P,Serra E,Barbieri S,Persona P,Rea F,Loy M,Ori C

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Pharmacologic stress testing is utilized in preference to exercise stress echocardiography (ESE) for cardiac risk evaluation in potential renal transplant recipients due to the perceived lower feasibility of ESE for achieving adequate workload and target heart rate (THR) in this population. METHODS:Consecut...

journal_title：Clinical transplantation

authors： Nerlekar N,Mulley W,Rehmani H,Ramkumar S,Cheng K,Vasanthakumar SA,Rashid H,Barton T,Nasis A,Meredith IT,Moir S,Mottram PM

更新日期：2016-10-01 00:00:00

abstract：:The main cause of late morbidity and mortality after lung transplantation is bronchiolitis obliterans syndrome (BOS). This study assesses the prevalence of gastroparesis among lung-transplant recipients and its association with BOS. The files of 139 patients who underwent nuclear gastric emptying studies before and/or...

journal_title：Clinical transplantation

authors： Raviv Y,D'Ovidio F,Pierre A,Chaparro C,Freeman M,Keshavjee S,Singer LG

更新日期：2012-01-01 00:00:00

abstract：:Accurate prognostic indicators are lacking for livers with early marginal graft function, making the decision to re-transplant a difficult one. Therefore, we studied 99mTc-labeled DISIDA scanning as a predictor of recovery of marginal grafts. Records of 28 liver transplant recipients with prolonged periods of marginal...

journal_title：Clinical transplantation

authors： Karademir S,Csete ME,Jurim O,Finstad T,Hawkins R,Bussuttil RW,Shaked A

更新日期：1994-02-01 00:00:00

abstract：:The progression of HCV-related disease is particularly aggressive in the post-transplantation setting. Recipients with recurrent HCV infection undergo repeated liver biopsies in order to estimate disease progression. A strong association was found between serum immunoglobulins levels and hepatic fibrosis in non-transp...

journal_title：Clinical transplantation

authors： Schmilovitz-Weiss H,Cohen M,Pappo O,Sulkes J,Braun M,Tur-Kaspa R,Ben-Ari Z

更新日期：2007-05-01 00:00:00

abstract：INTRODUCTION:Recent immunosuppression with tacrolimus and mycophenolate mofetil has improved the results of renal transplantation. In this study, we analyzed the effect and safety of basiliximab as an induction therapy. MATERIAL AND METHODS:Forty-nine kidney recipients were given tacrolimus, mycophenolate mofetil and ...

journal_title：Clinical transplantation

authors： Miura M,Harada H,Fukuzawa N,Iwami D,Taniguchi A,Seki T,Togashi M,Ogawa Y,Satoh H,Hirano T

更新日期：2005-01-01 00:00:00

abstract：:Calcineurin inhibitors (CNI) are the mainstay of immunosuppression after liver transplantation (LT), but CNIs are associated with significant nephrotoxicity. Recently, mTOR inhibitors such as sirolimus and everolimus (EVR) have been used with or without CNIs in LT recipients for their renal-sparing effect. We conducte...

journal_title：Clinical transplantation

authors： Lin M,Mittal S,Sahebjam F,Rana A,Sood GK

更新日期：2017-02-01 00:00:00

abstract：:We investigated tolerability and efficacy of ezetimibe treatment (10 mg/d) in 25 heart allograft recipients already on stable statin therapy. Total cholesterol (TC), low-density cholesterol (LDL-C), high-density cholesterol (HDL-C), triglycerides (TG), immunosuppressant drug levels, laboratory and clinical parameters ...

journal_title：Clinical transplantation

authors： Konstandin MH,Blessing E,Doesch A,Ammon K,Koch A,Wabnitz GH,Gleissner CA,Remppis A,Katus HA,Dengler TJ

更新日期：2008-09-01 00:00:00

abstract：:The purpose of this study was to compare CsA dose monitoring with trough levels (T0) vs. levels obtained 6 h after the morning dose of CsA (T6), with respect to the incidence of acute rejection and renal dysfunction, and the cumulative dose, as well as the cost of CsA after heart transplantation. Twenty consecutive ad...

journal_title：Clinical transplantation

authors： Cantarovich M,Besner JG,Fitchett DH,Latter DA

更新日期：1997-10-01 00:00:00

abstract：:Cutaneous cryptococcosis is an uncommon manifestation of disseminated cryptococcal disease. We report a liver transplant recipient presenting with onset over 3 days of progressive pain and swelling of the lower extremity and foot with erythema and heat. Cryptococcal cellulitis was documented, but in retrospect the cli...

journal_title：Clinical transplantation

authors： Singh N,Rihs JD,Gayowski T,Yu VL

更新日期：1994-08-01 00:00:00

abstract：:ABO-incompatibility is a major obstacle to expanding exiguous donor pools in adult liver transplantation, especially in countries where grafts from deceased donors are uncommon. We present our preliminary results of ABO-incompatible (ABO-I) adult living donor liver transplantation (LDLT) using a new, simple protocol. ...

journal_title：Clinical transplantation

authors： Soejima Y,Muto J,Matono R,Ninomiya M,Ikeda T,Yoshizumi T,Uchiyama H,Ikegami T,Shirabe K,Maehara Y

更新日期：2013-03-01 00:00:00

abstract：INTRODUCTION:Conversion from calcineurin inhibitor (CI)-based maintenance immunosuppression to sirolimus (SRL)-based immunosuppression may be beneficial in selected renal transplant recipients. The purpose of this study was to evaluate the safety and efficacy of a daclizumab (DAC) bridge protocol in patients converted ...

journal_title：Clinical transplantation

authors： Sundberg AK,Rohr MS,Hartmann EL,Adams PL,Stratta RJ

更新日期：2004-01-01 00:00:00

abstract：:Early steroid discontinuation (ESD) has been associated with a lower incidence of post-transplant diabetes mellitus (PTDM). We retrospectively reviewed the incidence of PTDM in relation to racial groups in kidney transplant recipients treated with ESD. Between January 2002 and September 2003, 125 consecutive primary a...

journal_title：Clinical transplantation

authors： Walczak DA,Calvert D,Jarzembowski TM,Testa G,Sankary HN,Thielke J,Oberholzer J,Benedetti E

更新日期：2005-08-01 00:00:00

abstract：:Unresponsive pulmonary hypertension (PH) implies poor posttransplant outcomes. Data on late adaptation of the right ventricle (RV) are still few. This study evaluated three-yr RV function and remodeling, exercise capacity, and hemodynamic data in a selected group of patients initially disqualified because of PH. Betwe...

journal_title：Clinical transplantation

authors： De Santo LS,Buonocore M,Agrusta F,Bancone C,Galdieri N,Romano G,Maiello C,Amarelli C

更新日期：2014-07-01 00:00:00

abstract：:This study investigated the association between religious beliefs and opinions on xenotransplantation among students from three different countries. A lower proportion of religious students accepted xenotransplantation than did non-religious students. A higher proportion of Protestant students seemed to accept xenotra...

journal_title：Clinical transplantation

authors： Hagelin J,Hau J,Schapiro SJ,Suleman MA,Carlsson HE

更新日期：2001-12-01 00:00:00

abstract：:Granulomatous interstitial nephritis (GIN) is a rare histologic diagnosis in renal allografts. We report three cases with GIN. Case 1: a 37-yr-old woman received a kidney from her mother. On follow-up 15 months later, serum creatinine was increased and a graft biopsy showed epithelioid granuloma in the center of massi...

journal_title：Clinical transplantation

authors： Hotta K,Fukasawa Y,Sasaki H,Seki T,Togashi M,Harada H

更新日期：2012-07-01 00:00:00

abstract：:Organ donor availability is the major limiting factor in pediatric liver transplantation, and many children succumb from their liver disease before a suitable donor can be found. In an attempt to overcome this shortage, reduced-size liver transplantation, split liver transplantation, and living-donor liver transplanta...

journal_title：Clinical transplantation

authors： Emond JC,Whitington PF,Broelsch CE

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Progressive familial intrahepatic cholestasis (PFIC) results in liver cirrhosis. Therefore, some PFIC patients require liver transplantation (LT). Although three types of PFIC have been identified, their etiologies include unknown mechanisms. PATIENTS:A total of 717 recipients who underwent living-donor LT ...

journal_title：Clinical transplantation

authors： Hori T,Egawa H,Takada Y,Ueda M,Oike F,Ogura Y,Sakamoto S,Kasahara M,Ogawa K,Miyagawa-Hayashino A,Yonekawa Y,Yorifuji T,Watanabe K,Doi H,Nguyen JH,Chen F,Baine AM,Gardner LB,Uemoto S

更新日期：2011-09-01 00:00:00

abstract：:Micafungin has been approved for the prophylaxis of Candida infections in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Here, we report a single-center experience of three different dose levels regarding efficacy, toxicity, and colonization with Candida ssp. in clinical practice. ...

journal_title：Clinical transplantation

authors： Langebrake C,Rohde H,Lellek H,Wolschke C,Kröger NM

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Despite a survival benefit from transplantation and acceptable outcomes, patients with human immunodeficiency virus (HIV+) face barriers to kidney transplantation. Little is known about the acceptance or decline of organ offers on their behalf because waitlist registry data do not include HIV serostatus. ME...

journal_title：Clinical transplantation

authors： Cohen JB,Locke JE,Shelton B,Reed RD,Mustian M,MacLennan P,Forde KA,Reese PP,Sawinski D

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:A long-term prospective randomized trial evaluating alemtuzumab, a humanized anti-CD52 monoclonal antibody, in a predominantly non-Caucasian population has yet to be reported. METHODS:Ninety deceased donor (DD) first renal transplant recipients were randomized into three different antibody induction group...

journal_title：Clinical transplantation

authors： Ciancio G,Burke GW,Gaynor JJ,Roth D,Kupin W,Rosen A,Cordovilla T,Tueros L,Herrada E,Miller J

更新日期：2008-03-01 00:00:00

abstract：:In recent years, several researchers have unraveled the previously unrecognized effects of granulocyte colony-stimulating factor (G-CSF) on hematopoiesis and the immune cell functions of bone marrow in healthy donors. In human leukocyte antigen-matched or haploidentical transplant settings, available data have establi...

journal_title：Clinical transplantation

authors： Chang YJ,Huang XJ

更新日期：2011-01-01 00:00:00

abstract：:Research with human transplant recipients has shown that mycophenolate mofetil (MMF) is a powerful and selective immunosuppressant for maintenance therapy following renal transplantation. An additional body of work suggests that it might also be a valuable tool for arresting ongoing rejection episodes. One randomized,...

journal_title：Clinical transplantation

authors：

更新日期：1996-02-01 00:00:00