Abstract:
BACKGROUND:We assessed the prevalence of mood disturbance among women with prospectively documented polycystic ovary syndrome (PCOS). METHODS:Thirty-two women with PCOS completed the Center for Epidemiological Studies-Depression Rating Scale (CES-D). Clinical and biochemical characteristics were assessed. RESULTS:Sixteen women had CES-D scores indicative of depression. Depression was associated with greater insulin resistance (P=0.02) and higher body mass index (P=0.05). Women receiving oral contraceptives for the treatment of PCOS were less depressed than patients not receiving treatment (P=0.03). LIMITATIONS:Possible selection bias, use of a screening tool alone without further diagnostic evaluation of depression, small samples size and lack of direct comparison with an age matched control group, should be considered in interpretation of these results. CONCLUSION:Findings suggest a high prevalence of depression among women with PCOS, and an association between depression and PCOS markers.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Rasgon NL,Rao RC,Hwang S,Altshuler LL,Elman S,Zuckerbrow-Miller J,Korenman SGdoi
10.1016/s0165-0327(02)00117-9subject
Has Abstractpub_date
2003-05-01 00:00:00pages
299-304issue
3eissn
0165-0327issn
1573-2517pii
S0165032702001179journal_volume
74pub_type
杂志文章abstract:BACKGROUND:Depression often co-occurs in late-life in the context of declining cognitive functions, but it is not clear whether specific depression symptom dimensions are differentially associated with cognitive abilities. METHODS:The study sample comprised 3107 community-dwelling older adults from the Longitudinal Ag...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2016.05.027
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Delayed diagnosis in bipolar disorder (BD) due to misdiagnosis as major depressive disorder (MDD) is a significant public health concern. Thus, identification of relevant diagnostic biomarkers is a critical unmet need, particularly early in the course of illness. The anterior cingulate cortex (ACC) is though...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.05.051
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Social anxiety disorder is fairly prevalent among alcohol abusing/dependent subjects. The objective of the present study was to investigate: (a) the incidence of social anxiety symptoms in inpatient alcoholics, (b) the effect of alcohol detoxification on these symptoms, and (c) whether a combined psychothera...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-0327(02)00094-0
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:Little is known about the duration of subsequent depressive episodes and periods of recovery, and much is based on potentially biased retrospective data. We therefore prospectively assessed whether duration of depressive episodes and recoveries is correlated within subjects and across episodes, and whether d...
journal_title:Journal of affective disorders
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jad.2009.12.013
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:According to published reports, the prevalence rates of major depressive disorder (MDD) in East-Asian countries are lower than in the West, but the reasons for this difference have not been fully investigated. METHODS:This study compared the Korean Epidemiologic Catchment Area study (KECAS) sample with the ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2007.07.023
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:Variations in circadian genes can impact biological rhythms. Given the rhythm disturbances that characterize bipolar disorder (BD), genes encoding components of molecular clocks are good candidate genes for the illness. METHODS:A family based association analysis of circadian gene single nucleotide polymorp...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.07.014
更新日期:2015-11-01 00:00:00
abstract:INTRODUCTION:Comprehensive understanding of the association between depression and neuropsychological functioning over the course of adolescence requires developmentally sensitive assessment through longitudinal data. The aim of current study is to examine the concurrent and subsequent effects of depressive symptoms on...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.11.060
更新日期:2018-03-15 00:00:00
abstract:BACKGROUND:The influence of seasons on mood disorders is controversial. OBJECTIVE:To examine monthly variations in admissions for mania and depressions including variations with sex and age and correlations with frequencies of suicides. METHODS:All admissions for mania or depression (N=4341) in a population of 1,800,...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00373-6
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:There have been few systematic studies of the treatment of bipolar II depression. While divalproex sodium (DVPX) is effective in acute mania, there are few data on the antidepressant effects of DVPX. Similarly, little is known regarding the use of DVPX administered in a single daily dose. METHOD:We performe...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章
doi:10.1016/s0165-0327(01)00434-7
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:Euthymic bipolar disorder (BD) patients often demonstrate better clinical outcomes than remitted patients with unipolar illness (UP). Reasons for this are uncertain, however, personality and coping styles are each likely to play a key role. This study examined differences between euthymic BD and UP patients ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.07.012
更新日期:2013-02-15 00:00:00
abstract:BACKGROUND:Altered emotional memory is one of the core cognitive functions that causes and maintains depression. Although many studies have investigated the relationship between hippocampal volume, depression and treatment response, no studies have investigated the relationship for hippocampal activity. Additionally, f...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.07.021
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Sleep spindles are believed to mediate several sleep-related functions including maintaining disconnection from the external environment during sleep, cortical development, and sleep-dependent memory consolidation. Prior studies that have examined sleep spindles in major depressive disorder (MDD) have not de...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.06.016
更新日期:2013-03-20 00:00:00
abstract:BACKGROUND:Various studies showed that personality traits and resilience might have impacts on depressive symptoms, separately. However, the relationships among personality traits, resilience and depressive symptoms are still undefined. Thus, this study tried to explore the potential effect of resilience on the associa...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.11.102
更新日期:2020-03-15 00:00:00
abstract:BACKGROUND:Little is known specifically about the association between generalized anxiety symptoms or panic and health care costs in older age. The aim of this study was to examine the association between generalized anxiety symptoms, panic and health care costs in people aged 65 and over. METHODS:Cross-sectional data...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.11.087
更新日期:2019-02-15 00:00:00
abstract:OBJECTIVE:To examine whether vitamin D deficiency or insufficiency is associated with depression and whether vitamin D supplementation is an effective treatment for depression. METHOD:Empirical papers published in recent years were identified using three search engines and online databases - PubMed, Google Scholar and...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2016.08.082
更新日期:2017-01-15 00:00:00
abstract:BACKGROUND:Borderline personality disorder (BPD) show different course and treatment compared to major depressive disorder (MDD). Early life stress may increase BPD onset; however, resilience may play a protective role against the development of psychopathology. The goal of this study was to compare the early life stre...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.04.119
更新日期:2018-08-15 00:00:00
abstract:BACKGROUND:Alcohol misuse and depression represent two major social and health problems globally. These conditions commonly co-occur and both are associated with significant cognitive impairment. Despite this, few studies have examined the impact on cognitive functioning of co-occurring alcohol misuse and depression. T...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2015.03.024
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:High levels of public spending, rising costs of treatments and scarcity of mental health resources have intensified the need for information on the cost-effectiveness of interventions for depression. There have been few reviews that consider the cost-effectiveness of all treatments for depression together. ...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jad.2004.10.003
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Depression treatment by General Practitioners (GPs) and patient outcomes improved significantly after a comprehensive 20-h training program of GPs. This study examines whether the effects on patient outcomes are caused by the improvements in the process of care. METHODS:Seventeen GPs participated in the tra...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/S0165-0327(03)00074-0
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:The Patient Health Questionnaire (PHQ-9) and Hospital Anxiety and Depression Scale (HADS) are commonly used measures in clinical practice and research. It is important that such scales measure the trait they purport to measure and that the impact of other measurement artefacts is minimal. Differential item f...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.11.015
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:To assess psychometric proprieties of the short version of TEMPS-M in an Italian clinical sample of patients with bipolar disorder type I (BDI), type II (BDI) or cyclothymic disorder (CYC). METHODS:All participants were recruited in two Italian university sites. They were asked to complete the Italian versi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.09.034
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The relationship between major depressive disorder (MDD) and dysthymia, a form of chronic depression, is complex. The two conditions are highly comorbid and it is unclear whether they are two separate disease entities. We investigated the extent to which patients with dysthymia superimposed on major depressi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.06.051
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Cross sectional research suggests that negative religious coping (e.g., anger at God and religious disengagement) strongly correlates with depression and anxiety. However, causality is difficult to establish as negative coping can accompany, cause, or result from distress. Among Orthodox Jews, some studies h...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.03.015
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:The association between cannabis use and mood disorders is well documented, yet evidence regarding causality is conflicting. This study explored the association between cannabis use, major depressive disorder (MDD) and bipolar disorder (BPD) in a 3-year prospective study. METHODS:Data was drawn from waves 1...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.10.006
更新日期:2015-02-01 00:00:00
abstract::Thyrotropin secreting hormone (TSH) levels were recorded in baseline conditions and 20 and 60 min after thyrotropin releasing hormone (TRH) administration (200 micrograms i.v.) in 60 depressed females categorized according to DSM-III. Basal TSH (TSHB) and peak TSH responses (TSHP) were measured using ultrasensitive RI...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(89)90075-x
更新日期:1989-03-01 00:00:00
abstract::To compare mortality in bipolar and unipolar manic-depressive patients, 2168 manic-depressive first admissions reported to the Danish Psychiatric Central Register were divided into a bipolar group (19%), i.e., patients with at least one admission for mania during an average observation period of six years, and a unipo...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(86)90074-1
更新日期:1986-11-01 00:00:00
abstract::Tricyclic antidepressants with clinically significant amounts of anticholinergic activity can adversely affect memory and cognitive functioning. The study evaluated the effect of two non-anticholinergic antidepressants, fluoxetine and trazodone, on immediate and short-term memory in clinically depressed outpatients. T...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0165-0327(90)90079-n
更新日期:1990-04-01 00:00:00
abstract:BACKGROUND:Stress-induced failed resilience of brain plasticity can contribute to the onset and recurrence of depression. Chronic stress has been reported to open windows of epigenetic plasticity in hippocampus. However, how hippocampal plasticity underlies depression-like behaviors and how it adapts in response to str...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.10.019
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:In the new global socioeconomic development, suicidal deaths have increased which is progressively gaining more attention in the field of psychiatry, social work, psychology, and public health research. The present study aimed at examining the evidence for the attitudes towards suicide and risk factors for s...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2020.03.135
更新日期:2020-07-01 00:00:00
abstract::In August 1939, at the 3rd International Neurological Congress in Copenhagen, Professor Lucio Bini reported on the first use of electricity to induce a seizure for therapeutic purposes in psychotic patients. At that time, the discovery of ECT amounted to a therapeutic revolution, helping millions of mentally ill patie...
journal_title:Journal of affective disorders
pub_type: 传,历史文章,杂志文章
doi:10.1016/j.jad.2009.01.023
更新日期:2010-01-01 00:00:00