Abstract:
:A brain model is proposed which describes its structural organization and the related functions as compartments organized in time and space. On a molecular level the negative feedback loops of clock-controlled genes are interpreted as compartments. This spatio-temporal operational principle may also work on the cellular level as glial-neuronal interactions, wherein glia have a spatio-temporal boundary setting function. The synchronization of the multi-compartmental operations of the brain is compared to the harmonization in a symphony and appears as an integrated behavior of the whole organism, defined as modes of behavior. For explanation of the principle of harmonization, an example from Schubert's Symphony No. 8 has been chosen. While harmonization refers to the synchronization of diverse systems, it seems appropriate to select the brain of a composer and the structure of musical composition as a paradigm towards a glial-neuronal brain theory. Finally, some limitations of experimental brain research are discussed and robotics are proposed as a promising alternative.
journal_name
Brain Cognjournal_title
Brain and cognitionauthors
Mitterauer B,Kopp Kdoi
10.1016/s0278-2626(03)00043-5subject
Has Abstractpub_date
2003-04-01 00:00:00pages
357-67issue
3eissn
0278-2626issn
1090-2147pii
S0278262603000435journal_volume
51pub_type
杂志文章abstract::Previously it has been shown that the left hemisphere, but not the right, of split-brain patients tends to match the frequency of previous occurrences in probability-guessing paradigms (Wolford, Miller, & Gazzaniga, 2000). This phenomenon has been attributed to an "interpreter," a mechanism for making interpretations ...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2004.08.038
更新日期:2005-03-01 00:00:00
abstract::The purpose of the present study is to analyze how the Slow Wave develops in the retention period on a visual Delayed Match-to-Sample task performed by 170 subjects between 6 and 26 years old, divided into 5 age groups. In addition, a neuropsychological test (Working Memory Test Battery for Children) was correlated wi...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2014.04.003
更新日期:2014-07-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1006/brcg.1993.1010
更新日期:1993-03-01 00:00:00
abstract::A longitudinal study of a left hemispherectomized boy (AB) was conducted to document linguistic evolution and maturation and determine the extent to which right hemisphere processes allow development of language. Resection of the left hemisphere occurred at age 5 years 6 months, following intractable epilepsy. Tests o...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract::The present study examines verbal working memory over time in boys with fragile X syndrome (FXS) compared to nonverbal mental-age (NVMA) matched, typically developing (TD) boys. Concomitantly, the relationship between cortisol-a physiological marker for stress-and verbal working memory performance over time is examine...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2015.12.002
更新日期:2016-02-01 00:00:00
abstract::Temporal preparation was assessed in 15 Alzheimer's disease (AD) patients, 20 persons with mild cognitive impairment (MCI) and 28 healthy older adults. Participants completed a simple reaction time task in which the preparatory interval duration varied randomly within two blocks (short versus long temporal window). Re...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2010.08.004
更新日期:2010-12-01 00:00:00
abstract::We studied aspects of clock cognition that might underlie the sensitivity of the CDT in screening for dementia of the Alzheimer type (DAT). Two groups, 15 patients with mild-moderate DAT and 15 controls, were assessed with the CDT and specially designed tests of clock-related cognition. Patients were impaired on the C...
journal_title:Brain and cognition
pub_type: 临床试验,杂志文章
doi:
更新日期:2002-07-01 00:00:00
abstract::The coupling of hand grasping stimuli and the subsequent grasp execution was explored in normal participants. Participants were asked to respond with their right- or left-hand to the accuracy of an observed (dynamic) grasp while they were holding precision or power grasp response devices in their hands (e.g., precisio...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2007.07.004
更新日期:2007-11-01 00:00:00
abstract::Previous research reported a priming effect for voices. However, the type of information primed is still largely unknown. In this study, we examined the influence of speaker's gender and emotional category of the stimulus on priming of non-speech vocalizations in 10 male participants, who performed a gender identifica...
journal_title:Brain and cognition
pub_type: 临床试验,杂志文章
doi:10.1016/j.bandc.2004.02.024
更新日期:2004-07-01 00:00:00
abstract::In order to determine the dissociability of face, voice, and personal name recognition, we studied the performance of 36 brain-lesioned patients and 20 control subjects. Participants performed familiarity decisions for portraits, voice samples, and written names of celebrities and unfamiliar people. In those patients ...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1006/brcg.1999.1196
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVE:Patients with schizophrenia often display deficits on tasks thought to measure "executive" processes. Recently, it has been suggested that reductions in fluid intelligence test performance entirely explain deficits reported for patients with focal frontal lesions on classical executive tasks. For patients wit...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2015.07.009
更新日期:2015-10-01 00:00:00
abstract::A 53-year-old right-handed woman had an extensive lesion in the left hemisphere due to an infarction caused by vasospasm secondary to subarachnoid bleeding. She exhibited persistent expressive-vocal amusia with no symptoms of aphasia. Evaluation of the patient's musical competence using the Montreal Battery for Evalua...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2016.01.003
更新日期:2016-03-01 00:00:00
abstract::The present study used the "tip-of-the-tongue" (TOT) experimental paradigm in a picture-naming task to explore the naming deficits of adolescents with dyslexia. As compared with a control group of typically developing readers, the adolescents with dyslexia had fewer correct responses and more TOT responses. When they ...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/s0278-2626(03)00112-x
更新日期:2003-11-01 00:00:00
abstract::Neural activity associated with self-referential processing of emotional stimuli was investigated using whole brain functional magnetic resonance imaging (fMRI). Fifteen healthy subjects underwent fMRI scanning while making judgments about positive and negative trait words in four conditions (self-reference, other-ref...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2008.07.010
更新日期:2009-02-01 00:00:00
abstract::When we learn to make one motor response to one visual stimulus and a different motor response to another, representations of these stimulus-response associations must be maintained to efficiently transduce perception into action. When an irrelevant distractor is presented adjacent to a target stimulus, interference i...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1006/brcg.1998.1008
更新日期:1998-08-01 00:00:00
abstract::Cognitive functioning was assessed in 69 left-handed males and females with a positive family history of left-handedness and in 77 left-handed and 55 right-handed males and females without familial left-handedness. Compared to females, males performed better on numerical reasoning and on two visuospatial tasks involvi...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1006/brcg.1995.1014
更新日期:1995-03-01 00:00:00
abstract::Observers indicated whether a stimulus presented to one visual field or the other consisted of two sine-wave gratings (the baseline stimulus) or those same two gratings with the addition of a 2 cycle per degree (cpd) component. When the absolute spatial frequencies of the baseline stimulus were low (0.5 and 1.0 cpd), ...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/0278-2626(91)90085-m
更新日期:1991-05-01 00:00:00
abstract::Valence-specific laterality effects have been frequently obtained in facial emotion perception but not in vocal emotion perception. We report a dichotic listening study further examining whether valence-specific laterality effects generalise to vocal emotions. Based on previous literature, we tested whether valence-sp...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2012.03.001
更新日期:2012-07-01 00:00:00
abstract::The existence of handedness differences in the retrieval of episodic memories is well-documented, but virtually all have been obtained under conditions of intentional learning. Two experiments are reported that extend the presence of such handedness differences to memory retrieval under conditions of incidental learni...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2011.07.003
更新日期:2011-10-01 00:00:00
abstract::The purpose of the current investigation was to examine the age-related changes in the performance of the two hands on the Annett pegboard (Annett, 1970). The current study was part of a large-scale study investigating the development of unimanual and bimanual performance. Three hundred and two right-handed individual...
journal_title:Brain and cognition
pub_type: 临床试验,杂志文章
doi:10.1016/j.bandc.2004.08.016
更新日期:2005-02-01 00:00:00
abstract::Research across domains has suggested that agents, the doers of actions, have a processing advantage over patients, the receivers of actions. We hypothesized that agents as "event builders" for discrete actions (e.g., throwing a ball, punching) build on cues embedded in their preparatory postures (e.g., reaching back ...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2017.09.001
更新日期:2017-12-01 00:00:00
abstract::Procedural memory, which is rooted in the basal ganglia, plays an important role in the implicit learning of motor and cognitive skills. Few studies have examined procedural learning in either Tourette syndrome (TS) or Attention Deficit Hyperactivity Disorder (ADHD), despite basal ganglia abnormalities in both of thes...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2017.06.009
更新日期:2017-10-01 00:00:00
abstract::Bilateral eye movements (EMs) have been associated with enhancements in episodic memory and creativity. We explored the influence of EMs on behavior and event related potential (ERP) responses during the Attention Network Test (ANT). Participants completed ANT trials after bilateral EMs or a center-fixation control ma...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2019.03.001
更新日期:2019-06-01 00:00:00
abstract::On each trial, after three squares of different sizes (inducing display) were sequentially presented at central fixation, a target square was briefly lateralized to the right or left hemisphere (RH or LH) of 24 normal right-handed males. Subjects determined whether or not the target differed in size from the third ind...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1006/brcg.1993.1031
更新日期:1993-07-01 00:00:00
abstract::The purpose of this study was to compare the validity of two models which contrast with each other in the manner in which they integrate neuropsychological tests into distinct prefrontal constructs. The first prefrontal model consists of five distinct functional constructs drawn from human clinical neuropsychology. Th...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/0278-2626(92)90037-m
更新日期:1992-05-01 00:00:00
abstract::Neuroimaging in pediatrics is accompanied by all the ethical dilemmas associated with neuroimaging in adults, magnified significantly. The defining characteristics of childhood make working ethically with the population particularly problematic. Children have not developed the rational capabilities necessary to make i...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/s0278-2626(02)00521-3
更新日期:2002-12-01 00:00:00
abstract::Sentence comprehension requires the assignment of thematic relations between the verb and its noun arguments in order to determine who is doing what to whom. In some languages, such as English, word order is the primary syntactic cue. In other languages, such as German, case-marking is additionally used to assign them...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2018.09.003
更新日期:2019-08-01 00:00:00
abstract::We find a spatially asymmetric allocation of attention in patients with traumatic brain injury (TBI) despite the lack of obvious asymmetry in neurological indicators. Identification performance was measured for simple spatial patterns presented briefly to a locus 5 degrees into the left or right hemifield, after precu...
journal_title:Brain and cognition
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.bandc.2006.10.003
更新日期:2007-06-01 00:00:00
abstract::The performance of 18 frontal lobe lesion (FL) and 10 frontal lobe dementia (FLD) patients on an associative memory test was compared with the performance of their matched normal controls. The FL group was severely impaired on cued and free recall and was moderately impaired on a recognition condition. Left FL patient...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1006/brcg.1999.1121
更新日期:1999-11-01 00:00:00
abstract::The study investigates the cortical representation of the visual and kinesthetic image of a rotated position of the head in highly (highs) and low hypnotizable individuals (lows) of both gender. Participants were invited to imagine maintaining their head rotated toward one side by seeing their chin aligned with their ...
journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2018.03.007
更新日期:2018-06-01 00:00:00