Abstract:
:Temporal preparation was assessed in 15 Alzheimer's disease (AD) patients, 20 persons with mild cognitive impairment (MCI) and 28 healthy older adults. Participants completed a simple reaction time task in which the preparatory interval duration varied randomly within two blocks (short versus long temporal window). Results indicated that AD and MCI patients had difficulty preparing for the shortest preparatory interval of the short temporal window. AD and MCI patients also had difficulty maintaining an optimal level of preparation up to 5 s within the short temporal window. These results suggest that AD and MCI patients might show difficulty preparing for rapidly occurring events and maintaining preparation over time. This phenomenon should be considered when using reaction time measures with such patients.
journal_name
Brain Cognjournal_title
Brain and cognitionauthors
Sylvain-Roy S,Bherer L,Belleville Sdoi
10.1016/j.bandc.2010.08.004subject
Has Abstractpub_date
2010-12-01 00:00:00pages
255-61issue
3eissn
0278-2626issn
1090-2147pii
S0278-2626(10)00112-0journal_volume
74pub_type
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