Abstract：
:Accumulating evidence indicates that individuals with schizophrenia manifest abnormalities in structures (cerebellum and basal ganglia) and neurotransmitter systems (dopamine) linked to internal-timing processes. A single-cue tone delay eyeblink conditioning paradigm comprised of 100 learning and 50 extinction trials was used to examine cerebellar timing circuits in 13 medicated patients with schizophrenia and 13 age- and sex-matched controls. Patients with schizophrenia showed impaired learning of the conditioned response compared to controls and also greater within-subject variability in the timing of their responses. These findings are consistent with models of schizophrenia in which timing deficits underlie information-processing abnormalities and clinical features of the disorder.
journal_name
Brain Cognjournal_title
Brain and cognitionauthors
Brown SM,Kieffaber PD,Carroll CA,Vohs JL,Tracy JA,Shekhar A,O'Donnell BF,Steinmetz JE,Hetrick WPdoi
10.1016/j.bandc.2004.09.011subject
Has Abstractpub_date
2005-06-01 00:00:00pages
94-108issue
1eissn
0278-2626issn
1090-2147pii
S0278-2626(04)00282-9journal_volume
58pub_type
临床试验,杂志文章abstract：:An issue of continued debate in the visuomotor control literature surrounds whether a 2D object serves as a representative proxy for a 3D object in understanding the nature of the visual information supporting grasping control. In an effort to reconcile this issue, we examined the extent to which aperture profiles for...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2013.02.005
更新日期：2013-06-01 00:00:00
abstract：:The present research investigated alternative explanations of heightened interference in AB-AC learning in individuals with memory loss related to medial temporal lobe dysfunction. In Experiment 1, patients with left or right temporal lobectomy and control subjects were administered the standard AB-AC test. Relative t...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1006/brcg.1996.0004
更新日期：1996-02-01 00:00:00
abstract：:There is ample evidence supporting the dissociation between the role of the left and right cerebral hemispheres in processing words and faces, respectively. Nevertheless, research has not yet studied the effect of perceptual asymmetry in memory context effect tasks using words and faces. Thus, the present study resear...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2016.09.005
更新日期：2016-11-01 00:00:00
abstract：:Schizophrenia may be associated with a fundamental disturbance in the temporal coordination of information processing in the brain, leading to classic symptoms of schizophrenia such as thought disorder and disorganized and contextually inappropriate behavior. Although a variety of behavioral studies have provided stro...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2009.06.009
更新日期：2009-12-01 00:00:00
abstract：:Food is essential to our survival. It is also one of the greatest pleasures of life. Over the last decade, our understanding about how the brain responds to food cues and guides food search and intake has greatly increased. This special issue brings together various perspectives and research approaches on food cogniti...
journal_title：Brain and cognition
pub_type： 社论
doi：10.1016/j.bandc.2016.09.007
更新日期：2016-12-01 00:00:00
abstract：:Expectancies about face-structure can be induced by viewing parts of faces, which generates constraints due to two types of knowledge: feature-content and configuration. In a first experiment ERPs were recorded when parts of familiar faces were completed with incongruent features (from another face), as opposed to con...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1006/brcg.1994.1039
更新日期：1994-09-01 00:00:00
abstract：:The visual system has the remarkable ability to generalize across different viewpoints and exemplars to recognize abstract categories of objects, and to discriminate between different viewpoints and exemplars to recognize specific instances of particular objects. Behavioral experiments indicate the critical role of th...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2012.04.009
更新日期：2012-10-01 00:00:00
abstract：UNLABELLED:The present study investigates cortical structures associated with personality dimension of positivity (POS) by using a standardized low-resolution brain electromagnetic tomography (sLORETA), which provides EEG localization measures that are independent of the recording reference. Resting EEG and self-report...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2015.04.003
更新日期：2015-07-01 00:00:00
abstract：:Procedural memory, which is rooted in the basal ganglia, plays an important role in the implicit learning of motor and cognitive skills. Few studies have examined procedural learning in either Tourette syndrome (TS) or Attention Deficit Hyperactivity Disorder (ADHD), despite basal ganglia abnormalities in both of thes...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2017.06.009
更新日期：2017-10-01 00:00:00
abstract：:Previous research has shown that the observation of actions and the execution of actions activate common neural systems. More recently, we have presented data showing that action observation of prehension primes subsequent execution (Castiello, Lusher, Mari, Edwards, & Humphreys, 2002). In the current paper we examine...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/s0278-2626(03)00210-0
更新日期：2003-12-01 00:00:00
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journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2014.10.005
更新日期：2014-12-01 00:00:00
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journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2008.06.006
更新日期：2009-02-01 00:00:00
abstract：:The ability to read emotional expressions from human face and voice is an important skill in our day-to-day interactions with others. How this ability develops may be influenced by atypical experiences early in life. Here, we investigated multimodal processing of fearful and happy face/voice pairs in 9-month-olds pren...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2014.12.001
更新日期：2015-04-01 00:00:00
abstract：:The Stroop color-naming task is one of the most widely studied tasks involving the inhibition of a prepotent response, regarded as an executive function. Several studies have examined performance on versions of the Stroop task under conditions of acute sleep deprivation. Though these studies revealed effects on Stroop...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2011.03.005
更新日期：2011-06-01 00:00:00
abstract：:This study examined whether AD affects the control of pointing movements. Sixteen older adults with probable AD and 10 age-matched healthy adults pointed at targets varying in size (3 and 7 mm in diameter) and located at three positions (at the midline and 33 degrees to the left and right). Results revealed the patien...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：:This study followed the development of four children with right-hemisphere injury on a series of manipulative classification tasks to determine whether and how early brain injury affects the development of spatial and class relations. The children were first tested at about 2 years of age. Their data were compared wit...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/0278-2626(85)90029-6
更新日期：1985-10-01 00:00:00
abstract：:Non-visual gaze patterns (NVGPs) involve saccades and fixations that spontaneously occur in cognitive activities that are not ostensibly visual. While reasons for their appearance remain obscure, convergent empirical evidence suggests that NVGPs change according to processing requirements of tasks. We examined NVPGs i...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2010.07.014
更新日期：2010-12-01 00:00:00
abstract：:In a previous study, the pattern of ear superiority displayed by nonmusicians in a task where dichotically presented target melodies have to be recognized among four probes was found to be correlated with subjects' descriptions of their operating modes: those who reported focusing on critical local differences in pitc...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/0278-2626(87)90121-7
更新日期：1987-04-01 00:00:00
abstract：:Decision-making over time is an important aspect of adaptive social functioning. The main goal of this study was to investigate the development of this ability in young children. A simplified version of the Iowa Gambling Task was given to 69 children at 3 ages (3, 4, and 6 years). Children were also given an awareness...
journal_title：Brain and cognition
pub_type： 临床试验,杂志文章
doi：10.1016/S0278-2626(03)00272-0
更新日期：2004-06-01 00:00:00
abstract：:Alzheimer's disease (AD) subjects, healthy elderly, and young adults interpreted a series of novel noun-noun expressions composed of familiar object words. Subjects interpreted each item by selecting one of three possible definitions: a definition in which the referents of each noun were associated together in a parti...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2004.08.049
更新日期：2005-12-01 00:00:00
abstract：:Fragile X syndrome is the world's most common hereditary cause of developmental delay in males and is now well characterized at the biological, brain and cognitive levels. The disorder is caused by the silencing of a single gene on the X chromosome, the FMR1 gene. The premutation (carrier) status, however, is less wel...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2008.11.006
更新日期：2009-04-01 00:00:00
abstract：:Previous literature suggests that Parkinson's disease is marked by deficits in timed behaviour. However, the majority of studies of central timing mechanisms in patients with Parkinson's disease have used timing tasks with a motor component. Since the motor abnormalities are a defining feature of the condition, the st...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2008.01.010
更新日期：2008-08-01 00:00:00
abstract：:The relation between hemispheric asymmetry and perceptual characteristics in general, and the spatial frequency content of input in particular, are discussed in reference to Peterzell's (1991) reply to a literature review by Christman (1989a). Three main points are presented: (1) there is evidence that spatial frequen...
journal_title：Brain and cognition
pub_type： 评论,杂志文章
doi：10.1006/brcg.1993.1009
更新日期：1993-01-01 00:00:00
abstract：:In this review of neuropsychological case studies, a number of dissociations are shown between different visual abilities including low-level motion perception, static form perception, form-from-motion perception and biological motion perception. These dissociations reveal counter-intuitive results. Specifically, high...
journal_title：Brain and cognition
pub_type： 杂志文章,评审
doi：10.1016/j.bandc.2010.07.009
更新日期：2010-11-01 00:00:00
abstract：:Due to its fast temporal evolution and its representation and integration among complex and widespread neural networks, the emotion perception process should preferably be examined by means of multimethodological approach. Indeed the indubitable vantage of acquiring both the autonomic (arousal-related) and the central...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2015.02.001
更新日期：2015-04-01 00:00:00
abstract：:We studied the influence of five variables on picture naming latencies in French adult subjects: frequency, age of acquisition and length of words, name agreement in oral naming, and visual complexity of pictures. 140 pictures were presented to 56 subjects with control of individual factors (age, educational level, ge...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：:Recently several event-related potential attention studies have described a prefrontal positivity at about the same latency as the posterior N2 (approximately 200-300 ms), variously termed the frontal selection positivity (FSP), the anterior P2 (P2a), or the frontal P3 (P3f). These components have a similar spatio-tem...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2004.03.006
更新日期：2004-10-01 00:00:00
abstract：:Older adults, like patients with dorsolateral frontal lobe lesions, have been shown to be progressively susceptible to errors of perseveration in the Wisconsin Card Sorting Test (WCST). This deficit may result from several types of endogenous adaptive control abilities. First, to enable behavioral modifications in res...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1006/brcg.2001.1506
更新日期：2002-08-01 00:00:00
abstract：:Transcranial direct current stimulation (tDCS) has been shown to enhance the efficacy and generalisation of working memory (WM) training, but there has been little systematic investigation into how coupling task-specific WM training with stimulation impacts more specifically on transfer to untrained tasks. This random...
journal_title：Brain and cognition
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.bandc.2020.105552
更新日期：2020-06-01 00:00:00
abstract：:Visual narratives like comics and films often shift between showing full scenes and close, zoomed-in viewpoints. These zooms are similar to the "spotlight of attention" cast across a visual scene in perception. We here measured ERPs to visual narratives (comic strips) that used zoomed-in and full-scene panels either t...
journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/j.bandc.2020.105634
更新日期：2020-12-01 00:00:00
