Abstract:
:The size, sign, and profile of induced circular dichroism (CD) features in the Soret region are reliable indicators of the binding modes of porphyrins and metalloporphyrins to DNA. Porphyrins shown (using such CD criteria) to be intercalators in monodispersed DNA duplexes prove extremely useful for the detection and characterization of organized, condensed forms of nucleic acids (psi-condensates). In addition, certain select porphyrin derivatives can form extended assemblies on nonaggregated DNA templates. A combination of CD and resonance light scattering (RLS) measurements allows for sensitive detection and characterization of these porphyrin arrays.
journal_name
Chiralityjournal_title
Chiralityauthors
Pasternack RFdoi
10.1002/chir.10206subject
Has Abstractpub_date
2003-05-05 00:00:00pages
329-32issue
4eissn
0899-0042issn
1520-636Xjournal_volume
15pub_type
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